840 results match your criteria iranian isolates

Molecular and biological characterization of a new mulberry idaeovirus.

Virus Res 2021 Apr 3;298:198411. Epub 2021 Apr 3.

Mustafa Kemal University, Plant Protection Department, Hatay, 31034, Turkey.

A virus-like disease with symptoms including mosaic structure, deformation, vein clearing and necrosis on the leaves and deformation, crumbling, and scab on the fruits was detected in black mulberry trees (Morus nigra L.) in Kayseri province of Turkey. A novel positive single-stranded RNA virus with a bipartite genome and the mulberry badnavirus 1 (MBV-1) were detected in the black mulberry trees by high throughput sequencing and bioinformatic analyses. Read More

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Detection and Phylogenetic Study of Peste des Petits Ruminants in Iran, 2019: Updated Data.

Arch Razi Inst 2021 Mar 1;76(1):161-166. Epub 2021 Mar 1.

Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Peste des Petits Ruminants (PPR) is caused by a morbillivirus from the Paramyxoviridae family and the infected animals, especially goats, that show clinical signs of necrotic stomatitis, enteritis, and pneumonia. The PPR virus has four lineages closely related to the geographical regions. Sufficient awareness of the lineage of the virus helps monitor the disease in different regions of a country. Read More

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Molecular Identification of Mycoplasma agalactiae in Iran Based on P30 Gene.

Arch Razi Inst 2021 Mar 1;76(1):61-68. Epub 2021 Mar 1.

Mycoplasma Reference Laboratory, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.

Mycoplasma agalactiae (M. agalactiae) is known as the main etiological agent of contagious agalactia (CA). The CA is a disease affecting dairy sheep and goats, the main characteristics of which include keratoconjunctivitis, arthritis, and mastitis. Read More

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Hemagglutinin-neuraminidase Sequence and Phylogenetic Analysis of Two Newcastle Disease Virus Isolated from Chickens in Iran.

Arch Razi Inst 2021 Mar 1;76(1):31-39. Epub 2021 Mar 1.

Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Newcastle disease is a highly contagious viral infection affecting many species of birds that can spread fast between poultry houses and cause a heavy economic burden on the poultry industry all around the world. Fusion and hemagglutinin-neuraminidase (HN) protein are important in the pathogenesis of the Newcastle disease virus (NDV). The HN protein is a critical viral protein with multiple functions and plays a key role in the formation of the virulence of NDV. Read More

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Effect of Type b Vaccination on Nasopharyngeal Carriage Rate in Children, Tehran, 2019.

Biomed Res Int 2021 15;2021:4923852. Epub 2021 Mar 15.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: () strains, which commonly reside as commensals within the human pharynx and can remain as an asymptomatic carrier, but become invasive leading to pneumonia, septic arthritis, or meningitis. The Pentavac (pentavalent vaccine, manufactured by India, SII (DTwP-HepB-Hib)) was introduced to the Iranian National Immunization Plan in November 2014. The aim of this study is to investigate type b () carrier rate among children under 6 years old in Tehran. Read More

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Molecular identification and antifungal susceptibility profiles of Candida dubliniensis and Candida africana isolated from vulvovaginal candidiasis: A single-center experience in Iran.

Mycoses 2021 Apr 3. Epub 2021 Apr 3.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.

Background: Vulvovaginal candidiasis (VVC) is a common and debilitating long-term illness affecting million women worldwide. This disease is caused mainly by Candida albicans and a lesser extent by other species, including the two phylogenetically closely related pathogens Candida africana and Candida dubliniensis.

Objectives: In this study, we report detailed molecular epidemiological data about the occurrence of these two pathogenic yeasts in Iranian patients affected by VVC, or its chronic recurrent form (RVVC), and provide, for the first time, data on the antifungal activity of two new drugs, efinaconazole (EFN) and luliconazole (LUL). Read More

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Molecular Epidemiology of Novirhabdoviruses Emerging in Iranian Trout Farms.

Viruses 2021 Mar 10;13(3). Epub 2021 Mar 10.

Institute of Microbiology and Virology, Medical School Brandenburg Theodor Fontane, 01968 Senftenberg, Germany.

Novirhabdoviruses cause large epizootics and economic losses of farmed trout. In this study, we surveyed Viral hemorrhagic septicemia virus and Infectious hematopoietic and necrosis virus (VHSV and IHNV) through both monitoring and investigation of clinical outbreaks reported by farmers in the regions with major rainbow trout production in Iran from 2015 to 2019. RT-PCR assays of the kidney samples and cell culture (EPC/FHM cells) samples confirmed the presence of the viruses, with 9 VHSV and 4 IHNV isolates, in both endemic and new areas of Iran. Read More

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Molecular, Morphological, and Spatial Study of (Pulmonata, Lymnaeidae) from Southeastern Iran.

Iran J Parasitol 2021 Jan-Mar;16(1):52-63

Research Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.

Background: Snails of the genus are the intermediate hosts of species the etiological agents of liver fluke disease, fascioliasis. A genetically different but morphologically very similar species in the genus, is sympatrically distributed with in some regions of the world. We aimed to investigate the occurrence of in Kerman province, Iran and to characterize genetically specimens from southeast Iran. Read More

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Infection rate and genetic diversity of assemblage C in Iranian stray dogs, targeting the gene.

Vet World 2021 Feb 16;14(2):419-425. Epub 2021 Feb 16.

School of Allied Health Sciences, Research Excellence Center for Innovation and Health Products, Walailak University, Nakhon Si Thammarat, Thailand.

Background And Aim: is one of the most common enteric protozoan parasites in vertebrates, such as humans, domestic and wild animals, causing giardiasis. To the best of our knowledge, little is known about the genetic diversity of assemblages. This study aimed to identify genetic diversity of assemblages in Iranian stray dogs. Read More

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February 2021

Growth optimization and identification of an ω-transaminase by a novel native PAGE activity staining method in a Bacillus sp. strain BaH isolated from Iranian soil.

AMB Express 2021 Mar 23;11(1):46. Epub 2021 Mar 23.

Karlsruhe Institute of Technology (KIT), BLT 2 Technical Biology, Fritz-Haber-Weg 4, Karlsruhe, Germany.

ω-Transaminases' (ω-TAs) importance for synthesizing chiral amines led to the development of different methods to quickly identify and characterize new sources of these enzymes. Here we describe the optimization of growth and induction of such an enzyme in a wild type strain of Bacillus sp. strain BaH (IBRC-M 11337) isolated from Iranian soil in shaking flasks by the response surface methodology (RSM). Read More

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SARS-CoV-2 Genome from the Khyber Pakhtunkhwa Province of Pakistan.

ACS Omega 2021 Mar 3;6(10):6588-6599. Epub 2021 Mar 3.

State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint International Research Laboratory of Metabolic & Developmental Sciences and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, P. R. China.

Among viral outbreaks, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest ones, and it has triggered the global COVID-19 pandemic. In Pakistan, until 5th September 2020, a total of 6342 deaths have been reported, of which 1255 were from the Khyber Pakhtunkhwa (KPK) province. To understand the disease progression and control and also to produce vaccines and therapeutic efforts, whole genome sequence analysis is important. Read More

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First report of Babesia occultans in two symptomatic cows in Iran.

Parasitol Res 2021 Mar 19. Epub 2021 Mar 19.

Department of Pathobiology, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, 6517658978, Iran.

This study reports the identification and first molecular characterization of Babesia occultans from naturally infected cows in Iran. Microscopic examination showed pyriform trophozoites, and ring-shaped merozoites (>2.5 μm) in Giemsa-stained blood smears obtained from two symptomatic cows in West-Azarbaijan province, Iran. Read More

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Characteristics of Clostridioides difficile colonization in Ilamian children.

Ann Ig 2021 May-Jun;33(3):209-219

Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.

Background: The increasing colonization with Clostridioides difficile in paediatric hospitalized population is a well known event; however, its prevalence in Iranian children has not effectively been identified yet.

Objective: The objective of this study was to determine the intestinal-carriage rates of C. difficile and molecular characterization of C. Read More

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First Evidence for Colonizing of Acanthamoeba T4 Genotype in Urinary Tracts of Patients with Recurrent Urinary Tract Infections.

Acta Parasitol 2021 Mar 13. Epub 2021 Mar 13.

Pulmonary and Critical Care Division, Toxoplasmosis Research Center, Iranian National Registry Center for Lophomoniasis and Toxoplasmosis, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Limited evidence about the presence of Acanthamoeba spp. in urine specimens collected from urinary catheters of the patients in the intensive care units persuaded our study. No evidence has been found about colonizing of Acanthamoeba spp. Read More

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Genetic diversity and antifungal susceptibility of Candida albicans isolates from Iranian HIV-infected patients with oral candidiasis.

BMC Res Notes 2021 Mar 10;14(1):93. Epub 2021 Mar 10.

Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, P.O. Box: 14155-6453, Tehran, Iran.

Objective: The objectives of this study were to investigate the antifungal susceptibility and genetic diversity of Candida albicans isolated from HIV patients with oropharyngeal candidiasis. A total of 50 C. albicans isolates were cultured on Sabouraud glucose agar containing chloramophenicol. Read More

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Stage-Specific Differential Gene Expression of Glutathione Peroxidase in and .

Rep Biochem Mol Biol 2020 Oct;9(3):324-330

Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: and are the etiological agents of cutaneous leishmaniosis. Leishmania species cause a board spectrum of phenotypes. A small number of genes are differentially expressed between them that have likely an important role in the disease phenotype. Read More

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October 2020

prediction of linear B-cell epitopes for S1 protein of two Iranian 793/B isolates and their changes after 90 serial passaging.

Vet Res Forum 2020 15;11(4):365-370. Epub 2020 Dec 15.

Department of Poultry Disease Research and Diagnosis, Razi Vaccine and Serum Research Institute, Karaj, Iran.

Neutralizing, serotype-specific, and hemagglutination-inhibiting antibodies against infectious bronchitis virus (IBV) are induced by epitopes in the S1 protein. Most changes in the virus genome due to mutation and recombination during serial passaging in embryonated chicken eggs occur in the S1 gene. In the current study, we tried to predict the potential linear B-cell epitopes of the S1 subunit of two Iranian 793/B isolates and then we analyzed their changes at passage level 90 due to mutations at this passage level. Read More

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December 2020

Molecular Characterization and Phylogeny of Taenia hydatigena and Echinococcus granulosus from Iranian Sheep and Cattle Based on COX1 Gene.

Curr Microbiol 2021 Apr 23;78(4):1202-1207. Epub 2021 Feb 23.

Diagnostic and Research Unit of Parasitic Diseases (DRUP), Department of Medical Parasitology, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt.

Hydatid cyst, the larval stage of Echinococcus granulosus, and Cysticercus tenuicollis, the larval stage of Taenia hydatigena, are prevalent in domestic, livestock, and wild ruminants. The main goal of this research was to identify the isolates of E. granulosus and C. Read More

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Clonal spread of multi-resistant Gallibacterium anatis isolates among Iranian broilers and layers.

Vet Res 2021 Feb 17;52(1):27. Epub 2021 Feb 17.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Gallibacterium anatis is a common cause of reproductive tract infection in chickens, which leads to reduced egg production and increased mortality. This study was undertaken to investigate prevalence of G. anatis in 12 poultry flocks originating from Iranian provinces with leading chicken production and to determine genetic diversity, antimicrobial resistance, and the presence of major antigens of the isolates investigated. Read More

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February 2021

Anti-mycobacterial activity of 22 Iranian endemic or rare plant extracts against multi-drug and extensively drug resistant Mycobacterium tuberculosis.

Comb Chem High Throughput Screen 2021 Feb 14. Epub 2021 Feb 14.

Tuberculosis Reference Laboratory, Shariati hospital, Mashhad University of Medical Sciences, Mashhad. Iran.

Background: Due to side-effects and lost efficacy of common drugs on new resistance strains of Mycobacterium tuberculosis (Mtb), investigation on novel drugs and natural compounds from rich source of endemic plants is required. Thus, in the present study, the anti-mycobacterial effect of 22 Iranian endemic or rare plant extracts on multi-drug resistance (MDR) and extensively-drug resistance (XDR) Mtb isolates was evaluated.

Methods: 22 Iranian endemic and rare plant species from 9 families were collected and extracted by methanol. Read More

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February 2021

Molecular epidemiology and carbapenem resistance of isolated from patients with burns.

J Wound Care 2021 Feb;30(2):135-141

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Objective: The aim of this study was to investigate the molecular epidemiology and carbapenem resistance mechanisms of isolated from patients with burns in Azerbaijan, Iran.

Method: was isolated from 38 patients with burns. Disk diffusion and agar dilution methods were used to determine antibiotic susceptibility patterns. Read More

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February 2021

Complete Sequence-Based Genotyping of mgc2/pvpA Genes in Chicken-Derived Mycoplasma gallisepticum Isolates of Iran.

Avian Dis 2020 12;64(4):507-516

Department of Avian Disease Research and Diagnostic, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj 3197619751, Iran.

Mycoplasma gallisepticum (MG) is a major pathogen of the poultry industry throughout the world. MG causes chronic respiratory disease in chickens and infectious sinusitis in turkeys. Despite constant improvements in the biosecurity of the poultry industry in Iran, MG infection still occurs and causes significant economic issues. Read More

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December 2020

Expression of RND efflux pumps mediated antibiotic resistance in Pseudomonas aeruginosa clinical strains.

Microb Pathog 2021 Apr 6;153:104789. Epub 2021 Feb 6.

Infectious Diseases Research Center, AJA University of Medical Sciences, Tehran, Iran. Electronic address:

Resistance-Nodulation-Division (RND) efflux pumps are responsible for multidrug resistance in Pseudomonas aeruginosa. The present study aimed to evaluate the overexpression of RND efflux pumps and its role in the antibiotic resistance of P. aeruginosa clinical isolates. Read More

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DNA barcoding of Iranian radicine freshwater snails begins to untangle the taxonomy and phylogeography of intermediate hosts of schistosomiasis and fasciolosis from the Middle East and across Central Asia.

Infect Genet Evol 2021 Apr 23;89:104728. Epub 2021 Jan 23.

Epidemiology Research Unit (ERU) Department of Veterinary and Animal Sciences, Northern Faculty, Scotland's Rural College (SRUC), An Lòchran, 10 Inverness Campus, Inverness, IV2 5NA, United Kingdom. Electronic address:

In the Middle East radicine snails are of considerable medical and veterinary importance acting as vectors of trematodes. In Iran, such snails are responsible for the transmission of the zoonotic trematodes Schistosoma turkestanicum and Fasciola gigantica. Historically, Radix gedrosiana has been incriminated as an important intermediate host for both trematodes, however, controversy remains over the snail's true taxonomic status. Read More

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LC-MS based identification of stylosin and tschimgine from fungal endophytes associated with .

Iran J Basic Med Sci 2020 Dec;23(12):1565-1570

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Objectives: is an Iranian medicinal plant. Tschimgine and stylosin are two of its major monoterpene derivatives. In this study, we proceeded to investigate some fungal endophytes from that can produce plant secondary metabolites. Read More

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December 2020

A Nuclear Magnetic Resonance-Based Metabolomic Study to Identify Metabolite Differences between Iranian Isolates of major and .

Iran J Med Sci 2021 Jan;46(1):43-51

Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Cutaneous leishmaniasis caused by species () is one of the most important parasitic diseases in humans. To gain information on the metabolite variations and biochemical pathways between , we used the comparative metabolome of metacyclic promastigotes in the Iranian isolates of and by proton nuclear magnetic resonance (H-NMR).

Methods: and were collected from three areas of Iran, namely Gonbad, Mashhad, and Bam, between 2017 and 2018, and were cultured. Read More

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January 2021

High prevalence of Campylobacter jejuni CC21 and CC257 clonal complexes in children with gastroenteritis in Tehran, Iran.

BMC Infect Dis 2021 Jan 23;21(1):108. Epub 2021 Jan 23.

Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Jalal-Ale-Ahmad Ave, Tehran, 14117-13116, Iran.

Background: Campylobacter jejuni (C. jejuni) is a leading cause of acute gastroenteritis in human worldwide. The aim of study was to assess the distribution of sialylated lipooligosaccharide (LOS) classes and capsular genotypes in C. Read More

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January 2021

Production and characterization of poly 3-hydroxybutyrate-co-3-hydroxyvalerate in wheat starch wastewater and its potential for nanoparticle synthesis.

Braz J Microbiol 2021 Jan 18. Epub 2021 Jan 18.

Department of Biotechnology, Iranian Research Organization for Science and Technology, Tehran, Iran.

Polyhydroxyalkanoates (PHAs) are polymers with biodegradable and biocompatible properties accumulated in a wide variety of bacterial strains. In the present study, active sludge, wheat starch wastewater (WSW), and oil wastewater were used for the isolation and screening of PHA-accumulating bacteria. WSW was then implemented as a cheap and economical culture medium for the production of PHAs by the selected isolate. Read More

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January 2021

Genotypic diversity and antifungal susceptibility pattern of Candida albicans species isolated from hospitalized paediatric patients with urinary tract infection in Iran.

J Appl Microbiol 2021 Jan 18. Epub 2021 Jan 18.

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Aims: The present study aimed to determine the microsatellite length polymorphism (MLP) genotypic patterns and antifungal susceptibility profiles of Candida albicans isolated from patients with candiduria.

Methods And Results: DNA of 50 C. albicans isolates was used for molecular identification based on the ITS -5. Read More

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January 2021