2,353 results match your criteria ipsilateral lung

Horner's syndrome secondary to heart surgery in a pediatric patient.

Saudi J Ophthalmol 2020 Oct-Dec;34(4):303-305. Epub 2021 Jul 29.

Department of Ophthalmology, Sütcü Imam University, Faculty of Medicine KSU Faculty of Medical, Kahramanmaraş, Turkey.

Horner's Syndrome (HS) is a disease characterized by miosis, ptosis, and ipsilateral lack of sweating. It can occur with any injury at the level of the ocular sympathetic system neurons from the hypothalamus to the cervical postganglionic fibers. We present here a case of HS that developed after heart surgery in a 9-year-old boy. Read More

View Article and Full-Text PDF

Right lung complete atelectasis: an endotracheal tube displacement complication.

Oxf Med Case Reports 2021 Sep 13;2021(9):omab085. Epub 2021 Sep 13.

Department of Cardiology, University Hospital of Larissa, Larissa, Greece.

A 78-year-old, overweight woman with a severe individual history of the cardiovascular system was admitted in the intensive care unit with acute pulmonary edema. Despite appropriate emergency treatment, the patient did not show any clinical improvement and emergency intubation was decided. Post-intubation physical examination revealed dullness to percussion, absent breath sounds and reduced chest excursion of the right hemithorax combined with a gradual drop in blood pressure and oxygen saturation. Read More

View Article and Full-Text PDF
September 2021

Comparing of two dimensional and three dimensional fully convolutional networks for radiotherapy dose prediction in left-sided breast cancer.

Sci Prog 2021 Jul-Sep;104(3):368504211038162

Department of Radiation Physics, 89680Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), China.

Fully convolutional networks were developed for predicting optimal dose distributions for patients with left-sided breast cancer and compared the prediction accuracy between two-dimensional and three-dimensional networks. Sixty cases treated with volumetric modulated arc radiotherapy were analyzed. Among them, 50 cases were randomly chosen to conform the training set, and the remaining 10 were to construct the test set. Read More

View Article and Full-Text PDF
September 2021

Benefit of Deep Inspiratory Breath Hold for Right Breast Cancer When Regional Lymph Nodes Are Irradiated.

Pract Radiat Oncol 2021 Sep 8. Epub 2021 Sep 8.

Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT. Electronic address:

Background: While DIBH is routinely utilized for left-sided breast cancers, its benefits for right-sided breast cancer (rBC) have yet to be established. We compared free-breathing (FB) and DIBH treatment plans for a cohort of rBC undergoing RNI to determine its potential benefits.

Methods: rBC patients considered for RNI (IMNs, supraclavicular field, +/- axilla) from 10/2017-5/2020 were included in this analysis. Read More

View Article and Full-Text PDF
September 2021

Tuberculosis presenting as metastatic lung cancer.

Int J Mycobacteriol 2021 Jul-Sep;10(3):327-329

Department of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Mycobacterium tuberculosis infection (TB) masquerading as lung tumor is well reported, but its mimicry as metastatic thoracic cancer is rare. We report the case of a young male who presented with clinical and radiological picture of lung cancer but investigations confirmed it as TB. A 35-year-old male, with 18-pack year of smoking history, presented with dry cough, anorexia, weight loss, and lower back and left hip pain. Read More

View Article and Full-Text PDF
September 2021

A dosimetric and radiobiological evaluation of VMAT following mastectomy for patients with left-sided breast cancer.

Radiat Oncol 2021 Sep 6;16(1):171. Epub 2021 Sep 6.

Department of Radiation Oncology, Jiangxi Cancer Hospital of Nanchang University, Nanchang, Jiangxi, 330029, People's Republic of China.

Background: To compare the dosimetric, normal tissue complication probability (NTCP), secondary cancer complication probabilities (SCCP), and excess absolute risk (EAR) differences of volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) for left-sided breast cancer after mastectomy.

Methods And Materials: Thirty patients with left-sided breast cancer treated with post-mastectomy radiation therapy (PMRT) were randomly enrolled in this study. Both IMRT and VMAT treatment plans were created for each patient. Read More

View Article and Full-Text PDF
September 2021

Mediastinales Staging.

Zentralbl Chir 2021 Aug 6;146(S 01):S33-S47. Epub 2021 Sep 6.

Klinik für Thoraxchirurgie, Thoraxzentrum Ruhrgebiet, Herne-Eickel, Deutschland.

Thorough mediastinal staging is pivotal for prognostic assessment and treatment planning in patients with non-small-cell lung cancer (NSCLC) without distant metastasis. It aims to answer the question of whether a technically and functionally feasible operation also makes sense from an oncological point of view. In case of a nodal-free mediastinum, primary surgical therapy can be considered. Read More

View Article and Full-Text PDF

Five-Fraction Prone Accelerated Partial Breast Irradiation: Long-Term Oncologic, Dosimetric, and Cosmetic Outcome.

Pract Radiat Oncol 2021 Aug 30. Epub 2021 Aug 30.

Department of Radiation Oncology, NYU Langone Health, New York, NY. Electronic address:

Purpose/objective(s): Randomized data support accelerated partial breast irradiation (APBI) for early-stage breast cancer with variable techniques and cosmesis outcomes. We have treated patients with 5-fraction prone external beam APBI for over a decade and herein report acute and late outcomes.

Materials/methods: Patients receiving APBI 600cGy x 5 between 2010-2019 were included. Read More

View Article and Full-Text PDF

Oxidized Regenerated Cellulose Sheets in Postoperative Intrathoracic Adhesions.

Ann Thorac Cardiovasc Surg 2021 Aug 25. Epub 2021 Aug 25.

Division of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.

Adhesiolysis is often necessary in intrathoracic adhesion during ipsilateral repeat lung resection. This procedure has a risk of surgical complications, including unintentional intraoperative damage of the pulmonary vessels or lung parenchyma. We used an oxidized regenerated cellulose (ORC) sheet to prevent intrathoracic adhesion after lung resection in 55 patients. Read More

View Article and Full-Text PDF

Comparison of whole breast dosimetry techniques - From 3DCRT to VMAT and the impact on heart and surrounding tissues.

J Med Radiat Sci 2021 Aug 25. Epub 2021 Aug 25.

Radiation Oncology Department, Princess Alexandra Hospital, Cancer Services, Brisbane, Queensland, Australia.

Introduction: Various techniques for whole breast radiation therapy (WBRT) have been reported to increase dose to contralateral tissues. Heart dose is of critical importance as there is no apparent dose threshold below which there is no risk. The aim of this study was to compare planning techniques for WBRT that achieves the best target dosimetry and lowest organ at risk (OAR) dose. Read More

View Article and Full-Text PDF

Breast metastases from primary lung cancer: a retrospective case series on clinical, ultrasonographic, and immunohistochemical features.

Transl Lung Cancer Res 2021 Jul;10(7):3226-3235

Department of Ultrasound, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.

Background: Lung cancer metastases to the breast are less common and consequently have received much less attention in clinical practice. The purpose of this study was to provide a better understanding of clinical, ultrasonographic, and immunohistochemical features of breast metastases from primary lung cancer.

Methods: This retrospective case series included patients with breast metastases from primary lung cancer between January 2012 and December 2020. Read More

View Article and Full-Text PDF

Dosimetric Comparison Between Helical Tomotherapy and Volumetric Modulated Arc Therapy in Patients With Malignant Pleural Mesothelioma.

Clin Oncol (R Coll Radiol) 2021 Aug 21. Epub 2021 Aug 21.

Department of Radiation Oncology, University Hospital Bonn, University of Bonn, Bonn, Germany.

Aims: To carry out a dosimetric comparison and constraints feasibility proof of adjuvant radiotherapy through helical tomotherapy or volumetric modulated arc therapy (VMAT) for malignant pleural mesothelioma patients after pleurectomy/decortication.

Materials And Methods: Retrospective calculations were carried out on previously acquired simulations. A whole-pleura volume with 50. Read More

View Article and Full-Text PDF

Incidental paratracheal air cyst in papillary thyroid cancer patient: a case report.

Gland Surg 2021 Jul;10(7):2334-2339

Department of Surgery, CHA Ilsan Medical Center, Cha University School of Medicine, Goyang-si, Gyeonggi-do, South Korea.

Paratracheal air cyst (PTAC) is a collection of air in the right posterior side of the trachea with an uncertain etiology. We report a papillary thyroid cancer patient with a PTAC that was removed during thyroid cancer surgery. A 68-year-old woman was diagnosed with right papillary thyroid cancer with suspicion of central lymph node metastasis. Read More

View Article and Full-Text PDF

Clinicopathological and molecular characterizations of pulmonary NUT midline carcinoma.

Cancer Med 2021 Sep 19;10(17):5757-5764. Epub 2021 Aug 19.

Department of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Beijing, China.

Introduction: Pulmonary nuclear protein of the testis (NUT) midline carcinoma (NMC) is a aggressive cancer with t (15, 19) translocation. Here we present the clinicopathological characteristics and molecular genetics alterations of primary pulmonary NMC.

Methods: Fluorescence in situ hybridization (FISH) assay was performed to evaluate NUT translocation. Read More

View Article and Full-Text PDF
September 2021

Pulmonary dose tolerance in hemithorax radiotherapy for Ewing sarcoma of the chest wall: Are we overestimating the risk of radiation pneumonitis?

Pediatr Blood Cancer 2021 Aug 16:e29287. Epub 2021 Aug 16.

Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.

Background: Children with chest wall Ewing sarcoma with malignant pulmonary effusion or pleural stranding require hemithorax radiation, often with plans that exceed lung constraints. We investigated disease control and pneumonitis in children requiring hemithorax radiation.

Procedure: Eleven children (median age 13 years) received hemithorax radiotherapy. Read More

View Article and Full-Text PDF

Comprehensive nodal breast VMAT: solving the low-dose wash dilemma using an iterative knowledge-based radiotherapy planning solution.

J Med Radiat Sci 2021 Aug 12. Epub 2021 Aug 12.

Radiation Oncology Department, Northern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Introduction: Aimed to develop a simple and robust volumetric modulated arc radiotherapy (VMAT) solution for comprehensive lymph node (CLN) breast cancer without increase in low-dose wash.

Methods: Forty CLN-breast patient data sets were utilised to develop a knowledge-based planning (KBP) VMAT model, which limits low-dose wash using iterative learning and base-tangential methods as benchmark. Another twenty data sets were employed to validate the model comparing KBP-generated ipsilateral VMAT (ipsi-VMAT) plans against the benchmarked hybrid (h)-VMAT (departmental standard) and bowtie-VMAT (published best practice) methods. Read More

View Article and Full-Text PDF

Stem cells from human exfoliated deciduous teeth relieve pain via downregulation of c-Jun in a rat model of trigeminal neuralgia.

J Oral Rehabil 2021 Aug 12. Epub 2021 Aug 12.

Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.

Background: Stem cells from human exfoliated deciduous teeth (SHED) have excellent immunomodulatory and neuroprotective abilities. It is possible that systemic SHED transplantation could ameliorate trigeminal neuralgia. The phosphorylation of c-Jun contributes to the development of hyperalgesia and allodynia. Read More

View Article and Full-Text PDF

Geometric and Dosimetric Changes in Tumor and Lung Tissue During Radiotherapy for Lung Cancer With Atelectasis.

Front Oncol 2021 22;11:690278. Epub 2021 Jul 22.

Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.

Background And Purpose: This article retrospectively characterized the geometric and dosimetric changes in target and normal tissues during radiotherapy for lung cancer patients with atelectasis.

Materials And Methods: A total of 270 cone beam computed tomography (CBCT) scans of 18 lung patients with atelectasis were collected. The degree and time of resolution or expansion of the atelectasis were recorded. Read More

View Article and Full-Text PDF

Postoperative complications and perioperative management of lung resection in patients with a history of oesophagectomy for oesophageal carcinoma.

Interact Cardiovasc Thorac Surg 2021 Aug;33(3):418-425

Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.


Objectives: Advances in chemoradiation have improved the long-term prognosis of oesophageal cancer, although perioperative management for lung resection postoesophagectomy is unknown. The purpose of this study was to investigate postoperative complications and perioperative management for lung resection postoesophagectomy.

Methods: Between 2002 and 2017, a total of 4694 patients underwent lung resections; of these, 79 were performed postoesophagectomy. Read More

View Article and Full-Text PDF

Evaluation of Auto-Planning for Left-Side Breast Cancer After Breast-Conserving Surgery Based on Geometrical Relationship.

Technol Cancer Res Treat 2021 Jan-Dec;20:15330338211033050

Department of Radiation Oncology, Yunnan Cancer Hospital, the Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.

Purpose: This study aimed to evaluate (1) the performance of the Auto-Planning module embedded in the Pinnacle treatment planning system (TPS) with 30 left-side breast cancer plans and (2) the dose-distance correlations between dose-based patients and overlap volume histogram-based (OVH) patients.

Method: A total of 30 patients with left-side breast cancer after breast-conserving surgery were enrolled in this study. The clinical manual-planning (MP) and the Auto-Planning (AP) plans were generated by Monaco and by the Auto-Planning module in Pinnacle respectively. Read More

View Article and Full-Text PDF

Comparison of volumetric modulated arc therapy and intensity-modulated radiotherapy for left-sided whole-breast irradiation using automated planning.

Strahlenther Onkol 2021 Aug 5. Epub 2021 Aug 5.

Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

Background: Published treatment technique comparisons for postoperative left-sided whole breast irradiation (WBI) with deep-inspiration breath-hold (DIBH) are scarce, small, and inconclusive. In this study, fully automated multi-criterial plan optimization, generating a single high-quality, Pareto-optimal plan per patient and treatment technique, was used to compare for a large patient cohort 1) intensity modulated radiotherapy (IMRT) with two tangential fields and 2) volumetric modulated arc therapy (VMAT) with two small tangential subarcs.

Materials And Methods: Forty-eight randomly selected patients recently treated with DIBH and 16 × 2. Read More

View Article and Full-Text PDF

New horizons in non-small-cell lung cancer patients with ipsilateral pleural dissemination (M1a): review of the literature.

Ann Transl Med 2021 Jun;9(11):959

Department of Thoracic Surgery, Centre of Thoracic Minimally Invasive Surgery, Peking University People's Hospital, Beijing, China.

Non-small cell lung cancer (NSCLC) with ipsilateral pleural dissemination (pM1a) is generally contraindicated for surgery owing to the extremely poor survival. However, some studies have demonstrated that primary tumor resection (PTR) may prolong the survival of these patients. Besides, with the development of systemic therapy, it is still hard to decide the best therapy model for pM1a patients. Read More

View Article and Full-Text PDF

Development and External Validation of a Nomogram for Predicting Cancer-Specific Survival of Non-Small Cell Lung Cancer Patients With Ipsilateral Pleural Dissemination.

Front Oncol 2021 19;11:645486. Epub 2021 Jul 19.

Department of Thoracic Surgery, Centre of Thoracic Minimally Invasive Surgery, Peking University People's Hospital, Beijing, China.

Background: Non-small-cell lung cancer (NSCLC) patients with ipsilateral pleural dissemination are defined as M1a in the eighth of American Joint Committee on Cancer (AJCC) TNM staging. We aimed to build a nomogram to predict lung cancer specific survival (LCSS) of NSCLC patients with ipsilateral pleural dissemination and to compare the impact of primary tumor resection (PTR) on LCSS among patients with different features.

Methods: A total of 3,918 NSCLC patients with ipsilateral pleural dissemination were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Read More

View Article and Full-Text PDF

Magnetic Resonance Imaging Assessment of Pulmonary Vascularity in Infants with Congenital Diaphragmatic Hernia: A Novel Tool for Direct Assessment of Severity of Pulmonary Hypertension and Hypoplasia.

J Pediatr 2021 Jul 30. Epub 2021 Jul 30.

The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Center for Pulmonary Imaging Research, Division of Pulmonary Medicine and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Fetal Care Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Electronic address:

Objectives: To assess the feasibility of magnetic resonance imaging (MRI) for postnatal assessment of pulmonary vascularity in infants with congenital diaphragmatic hernia (CDH).

Study Design: Infants with prenatally diagnosed CDH (n = 24) received postnatal pulmonary MRI. Infants with nonpulmonary birth defects served as controls (n = 5). Read More

View Article and Full-Text PDF

NeoAPACHE II. Relationship Between Radiographic Pulmonary Area and Pulmonary Hypertension, Mortality, and Hernia Recurrence in Newborns With CDH.

Front Pediatr 2021 12;9:692210. Epub 2021 Jul 12.

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Congenital diaphragmatic hernia is a rare disease with high mortality and morbidity due to pulmonary hypoplasia and pulmonary hypertension. The aim of the study is to investigate the relationship between radiographic lung area and systolic pulmonary artery pressure (sPAP) on the first day of life, mortality, and hernia recurrence during the first year of life in infants with a congenital diaphragmatic hernia (CDH). A retrospective data collection was performed on 77 CDH newborns. Read More

View Article and Full-Text PDF

Lung cancer metastasis mimicking fingertip osteomyelitis: An F-fluorodeoxyglucose positron emission tomography-computed tomography study.

World J Nucl Med 2021 Apr-Jun;20(2):185-187. Epub 2020 Oct 23.

Department of Nuclear Medicine, "Ospedali Riuniti" Hospital, Ancona, Italy.

Lung cancer commonly metastasizes to ipsilateral and contralateral lungs, to mediastinal lymph nodes, to skeletal level, to brain, and to adrenal gland. It is indeed very rare to find skeletal metastases at the extremities, especially at the onset of the disease. We share the case of a 53-year-old man with dyspnea and pain at the level of the first finger of the left hand under antibiotic treatment for suspected osteomyelitis. Read More

View Article and Full-Text PDF
October 2020

Target coverage and cardiopulmonary sparing with the updated ESTRO-ACROP contouring guidelines for postmastectomy radiation therapy after breast reconstruction: a treatment planning study using VMAT and proton PBS techniques.

Acta Oncol 2021 Jul 27:1-12. Epub 2021 Jul 27.

Harvard Radiation Oncology Program, Boston, MA, USA.

Background: The European Society for Therapeutic Radiology and Oncology Advisory Committee in Radiation Oncology Practice (ESTRO-ACROP) recently released new contouring guidelines for postmastectomy radiation therapy (PMRT) after implant-based reconstruction (IBR). As compared to prior ESTRO guidelines, the new guidelines primarily redefined the chest wall (CW) target to exclude the breast prosthesis. In this study, we assessed the impact of these changes on treatment planning and dosimetric outcomes using volumetric-modulated arc therapy (VMAT) and proton pencil-beam scanning (PBS) therapy. Read More

View Article and Full-Text PDF

Comparison of the dosimetric accuracy of proton breast treatment plans delivered with SGRT and CBCT setups.

J Appl Clin Med Phys 2021 Sep 20;22(9):153-158. Epub 2021 Jul 20.

Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

Purpose: To compare the dosimetric accuracy of surface-guided radiation therapy (SGRT) and cone-beam computed tomography (CBCT) setups in proton breast treatment plans.

Methods: Data from 30 patients were retrospectively analyzed in this IRB-approved study. Patients were prescribed 4256-5040 cGy in 16-28 fractions. Read More

View Article and Full-Text PDF
September 2021

Dosimetric Comparison of Whole Breast Radiotherapy Using Field-in-Field and Volumetric Modulated Arc Therapy Techniques in Left-Sided Breast Cancer Patients.

Cureus 2021 Jun 18;13(6):e15732. Epub 2021 Jun 18.

Department of Clinical and Radiation Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

Introduction The radiotherapy of left-sided breast cancers is challenging because of neighboring critical organs, posing an increased risk of complications. Various radiation delivery techniques have been used to deliver the desired dose of radiation to the target area while keeping the doses to nearby structures within constraints. The main aim of this study is to quantify doses delivered to the organs at risk (OARs) including heart, left lung, spinal cord, and contralateral breast, and to the planning target volume (PTV) using Field-in-Field (FIF) and Volumetric Modulated Arc Therapy (VMAT). Read More

View Article and Full-Text PDF