Gynecol Obstet Fertil Senol 2021 Apr 2. Epub 2021 Apr 2.
Centre de Référence sur les Agents Tératogènes (CRAT), DMU ESPRIT (Épidémiologie et biostatistique, Santé publique, Pharmacie, Pharmacologie, Recherche, Information médicale, Thérapeutique et médicaments), GHU APHP Sorbonne Université, Site Trousseau 26 av Dr Netter, 75571, Paris cedex 12, France. Electronic address:
Despite the widespread use of triptans in the treatment of migraine during pregnancy, questions relating to their vasoconstrictive properties have been raised following recent reports of rare fetal deaths and intrauterine growth restrictions. However, to date, analysis of these data does not allow to conclude to a direct effect of triptans, which remain a second line treatment of migraine attacks during pregnancy at any term and under normal conditions of use. Read More