134 results match your criteria intrarenal reflux


Contrast-enhanced voiding urosonography for the diagnosis of vesicoureteral reflux and intrarenal reflux: a comparison of diagnostic performance with fluoroscopic voiding cystourethrography.

Ultrasonography 2021 Feb 10. Epub 2021 Feb 10.

Department of Radiology, Seoul National University Hospital, Seoul, Korea.

Purpose: This study evaluated the diagnostic performance of contrast-enhanced voiding urosonography (ce-VUS) using a second-generation ultrasound contrast agent for the diagnosis of vesicoureteral reflux (VUR) and intrarenal reflux (IRR), and compared it with that of standard fluoroscopic voiding cystourethrography (VCUG).

Methods: Thirty-two consecutive children from April to September 2019 were included in this study. ce-VUS and VCUG were performed simultaneously by two operators with intravesical infusion of a mixture of ultrasound contrast medium, iodinated contrast medium and water. Read More

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February 2021

Intrarenal Reflux in the Light of Contrast-Enhanced Voiding Urosonography.

Front Pediatr 2021 2;9:642077. Epub 2021 Mar 2.

University Hospital Split, Split, Croatia.

The aim of this study was to analyze the incidence of intrarenal reflux (IRR) among vesicoureteral refluxes (VURs), diagnosed by contrast-enhanced voiding urosonography (ceVUS), to define VURs which are positive to IRR and their locations in the kidney. Seventy patients with VURs, including 103 uretero-renal units (URUs) with VURs of grades II-V (37 URUs were excluded because of renal anomalies or absence of VUR) were examined with ceVUS due to recurrent febrile UTI or first febrile UTI accompanied by abnormalities on renal ultrasonography. Patients were examined on GE Logiq S8 ultrasound machine, using second generation of ultrasound contrast agent. Read More

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Contrast-enhanced voiding urosonography in the diagnosis of intrarenal reflux.

J Ultrasound 2021 Feb 26. Epub 2021 Feb 26.

Children's Hospital Zagreb, Ul. Vjekoslava Klaića 16, 10000, Zagreb, Croatia.

Purpose: Although contrast-enhanced urosonography (ceVUS) has shown capable diagnostic accuracy for the diagnosis of vesicoureteral reflux (VUR) in children, the ability of ceVUS to detect intrarenal reflux (IRR) is considered limited. The purpose of our study is to assess the ability of ceVUS to detect IRR as well as its association with age, gender, and the grade of VUR.

Methods: This study included 5153 children who were referred to our clinic for ceVUS. Read More

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February 2021

[Role of pressure and temperature in ureterorenoscopy and percutaneous nephrolitholapaxy : Pressure and temperature changes during stone treatment].

Urologe A 2019 Nov;58(11):1289-1297

UroClinic München an der Oper, Residenzstraße 18, München, Deutschland.

Ureterorenoscopy and percutaneous nephrolitholapaxy are minimally invasive procedures and are the standard procedures for the treatment of kidney stones and ureteral calculi. To achieve an adequate view, in both methods an optimal and sufficient irrigation flow is necessary. The intrarenal pressure is influenced by the irrigation pressure and irrigation volume and has to be controlled. Read More

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November 2019

Large Hepatic Subcapsular Hematoma Secondary to Double-J Stent Placement.

J Endourol Case Rep 2019 30;5(3):85-87. Epub 2019 Aug 30.

Hospital Alemán de Buenos Aires, Buenos Aires, Argentina.

Urinary diversion with the endoscopic Double-J stent is a frequent procedure; complications can include irritation, suprapubic or flank pain, vesicoureteral reflux, hematuria, or urinary infection. We report a case of hepatic subcapsular hematoma secondary to Double-J stent placement. A 28-year-old woman presented with a history of Sjögren's disease, nephrocalcinosis, and chronic kidney disease (CKD). Read More

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Urinary Ascites and Transient Intestinal Obstruction in a Preterm Infant: An Interesting Case of Posterior Urethral Valve.

AJP Rep 2019 Jul 10;9(3):e209-e212. Epub 2019 Jul 10.

Division of Neonatology/Nephrology, Department of Pediatrics, Brookdale Hospital Medical Center, New York, New York.

Posterior urethral valve (PUV) is the most common congenital cause of bladder outflow obstruction in male neonates. We report a preterm neonate with PUV who presented as nonimmune fetal hydrops with intestinal obstruction in the antenatal period. The mother of our patient is a 33-year-old woman who started her prenatal care at our hospital at 30 weeks' gestation. Read More

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Intrarenal reflux, an overlooked entity - retrospective analysis of 1,166 voiding cysturethrographies in children.

Pediatr Radiol 2019 05 25;49(5):617-625. Epub 2019 Jan 25.

Department of Pediatric Radiology, Klinikum der Universität München, Lindwurmstr. 4, 80337, Munich, Germany.

Background: The significance of intrarenal reflux as a risk factor for renal scarring and hypertension has been discussed. Fluoroscopic detection of intrarenal reflux depends on the equipment, the training of the radiologists and the timing of spot film acquisition.

Objective: To evaluate the prevalence of intrarenal reflux and its association with age, gender, grade of vesico-uretero-renal reflux and the renal segments affected. Read More

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Retrograde intrarenal surgery using ureteral access sheaths is a safe and effective treatment for renal stones in children weighing <20 kg.

J Pediatr Urol 2018 02 11;14(1):59.e1-59.e6. Epub 2017 Nov 11.

U.O.C. Urologia Pediatrica, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Introduction: Surgical treatment of pediatric kidney stones has changed dramatically in recent years because of the miniaturization of surgical instruments and the availability of intracorporeal lithotripters. The retrograde intrarenal surgery (RIRS) technique is nowadays considered an effective and safe procedure but studies in very young children are lacking and use of a ureteral access sheath (UAS) has also been debated.

Objective: To assess safety and efficacy of RIRS using UAS in children weighing < 20 kg. Read More

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February 2018

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis.

J Vis Exp 2017 07 18(125). Epub 2017 Jul 18.

Department of Radiology, Case Western Reserve University; Department of Pediatrics, Case Western Reserve University; Department of Biomedical Engineering, Case Western Reserve University;

Pyelonephritis is a bacterial infection of the kidney and is most commonly caused by Escherichia coli. Recurrent infections can cause significant renal inflammation and fibrosis ultimately resulting in declining kidney function. Before improved clinical management and prevention of pyelonephritis can be instituted, a reliable animal model must be established in order to study the mechanisms of progression, recurrence, and therapeutic efficacy. Read More

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Flexible ureteroscopic lithotripsy for the treatment of upper urinary tract calculi in infants.

Exp Biol Med (Maywood) 2017 01 4;242(2):153-159. Epub 2016 Oct 4.

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

We evaluated the clinical value of flexible ureteroscopic lithotripsy for the treatment of upper urinary tract calculi in infants. Fifty-five infants with upper urinary tract calculi were included in this study: 41 males and 14 females. Retrograde intrarenal surgery was performed by an 8 Fr/30 cm flexible ureterorenoscope (POLY®) combined with a holmium laser. Read More

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January 2017

A Preliminary Study Into the Significance of Intrarenal Reflux in BK Virus Nephropathy After Kidney Transplantation.

Transplant Direct 2016 Feb 15;2(2):e64. Epub 2016 Jan 15.

Department of Surgical Pathology, Tokyo Women's Medical University, Tokyo, Japan.

Background: The BK virus typically colonizes the lower urinary tract and is the causative agent in BK virus nephropathy (BKVN), which can progress to allograft dysfunction and graft loss. Urinary reflux in kidney allografts is induced by vesicoureteral reflux or disturbances in intrarenal reflux (IRR), believed to be associated with BKVN. This study was designed to elucidate the relationship between BKVN and IRR. Read More

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February 2016

Intrarenal Reflux: Diagnosis at Contrast-Enhanced Voiding Urosonography.

J Ultrasound Med 2016 Aug 1;35(8):1811-9. Epub 2016 Jul 1.

Department of Radiology, Boston Children's Hospital, and Harvard Medical School, Boston, Massachusetts USA.

Vesicoureteral reflux (VUR) is a childhood condition that is usually diagnosed by fluoroscopic voiding cystourethrography (VCUG). Intrarenal reflux (IRR) of infected urine is believed to play an important role in the pathogenesis of reflux-associated pyelonephritis and subsequent parenchymal scarring and is traditionally depicted by fluoroscopic VCUG. This case series describes the phenomenon of IRR occurring in association with VUR in 4 children as depicted by contrast-enhanced voiding urosonography. Read More

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Clinical Scenarios in Chronic Kidney Disease: Chronic Tubulointerstitial Diseases.

Contrib Nephrol 2016 12;188:108-19. Epub 2016 May 12.

Chronic tubulointerstitial diseases are a common final pathway toward chronic renal failure regardless the primary damage (glomerular, vascular or directly the tubulointerstitium). Chronic tubulointerstitial nephritis (CTN) is characterized by interstitial scarring, fibrosis and tubule atrophy, resulting in progressive chronic kidney disease. Most frequent causes of CTN are drugs, heavy metals, obstructive uropathy, nephrolithiasis, reflux disease, immunologic diseases, neoplasia, ischemia, metabolic diseases, genetics and miscellaneous. Read More

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December 2017

Double Coaxial Microcatheter Technique for Glue Embolization of Renal Arteriovenous Malformations.

Cardiovasc Intervent Radiol 2015 Oct 8;38(5):1277-83. Epub 2015 Aug 8.

Department of Radiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

Purpose: To demonstrate the technical benefit of the double coaxial microcatheter technique for embolization of renal arteriovenous malformations (AVMs) with n-butyl cyanoacrylate and iodized oil (glue).

Materials And Methods: Six consecutive patients (1 man and 5 women; mean age 61 years; range 44-77 years) with renal AVMs were included. Five patients had hematuria, and one had a risk of heart failure due to a large intrarenal arteriovenous shunt. Read More

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October 2015

Endoluminal pharmacologic stimulation of the upper urinary tract.

Dan Med J 2013 May;60(5):B4642

Department of Urology, University Hospital of Southern Denmark, Sdr. Boulevard 29, 5000 Odense C, Denmark.

The experiments performed in this PhD thesis were conducted at the Institute of Experimental Surgery, Skejby Hospital, Aarhus, Denmark and at the Laboratory of Animal Science, Odense University Hospital, Denmark. The thesis is based on 3 peer review articles published in international journals and a review. Diagnostic or therapeutic endoscopic upper urinary tract procedures are usually characterised as minimal invasive procedures and associated with a low complication rate. Read More

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Intrarenal reflux in primary vesicoureteral reflux.

Int J Urol 2013 Jun 27;20(6):631-6. Epub 2012 Nov 27.

Department of Urology, Aichi Children's Health and Medical Center, Obu, Aichi, Japan.

Objectives: To elucidate the significance of intrarenal reflux.

Methods: We retrospectively analyzed 276 patients (age <5 years) with grade III to V vesicoureteral reflux. They were divided into two groups: 55 patients with intrarenal reflux and 221 patients without intrarenal reflux (control group). Read More

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Vesicoureteral reflux and bladder dysfunction.

Transl Androl Urol 2012 Sep;1(3):153-9

Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.

The relationship between vesicoureteral reflux and bladder dysfunction is inseparable and has long been emphasized. However, the primary concern of all physicians treating patients with vesicoureteral reflux is the prevention of renal scarring and eventual deterioration of renal function. Bladder dysfunction, urinary tract infection and vesicoureteral reflux are the three important factors which are closely related to each other and contribute to the formation of renal scar. Read More

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September 2012

Outcomes of intrarenal Bacillus Calmette-Guérin/interferon-α2B for biopsy-proven upper-tract carcinoma in situ.

J Endourol 2012 Dec 9;26(12):1645-50. Epub 2012 Oct 9.

Department of Urology, Columbia University Medical Center, New York, NY, USA.

Background And Purpose: While nephroureterectomy (NU) remains the gold-standard treatment for upper-tract carcinoma in situ (UT-CIS), it may be unnecessarily aggressive in comparison with the treatment of bladder CIS. Upper-tract administration of bacillus Calmette-Guérin (BCG) has shown promise for UT-CIS, but with limited reports and varied results. Furthermore, all previous reports included patients with positive cytology results without biopsy-proven CIS, or combined BCG with other topical therapies that are used for bladder CIS. Read More

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December 2012

Predicting factors of breakthrough infection in children with primary vesicoureteral reflux.

Yonsei Med J 2012 Jul;53(4):748-52

Department of Urology, Catholic University of Daegu, School of Medicine, Daegu, Korea.

Purpose: Many pediatric urologists still favor using prophylactic antibiotics to treat children with vesicoureteral reflux (VUR). However, breakthrough infection sometimes occurs, leading to significant increases in morbidity as a result of renal scarring. Therefore, we tested whether abnormal renal scan and other factors are predictive of breakthrough infection using univariate analyses. Read More

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Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis.

Clin Exp Nephrol 2012 Dec 3;16(6):875-82. Epub 2012 May 3.

Department of Pediatrics, Kinki University School of Medicine, 377-2 Ohno-higashi, Osaka-Sayama 589-8511, Japan.

Background: Secondary focal segmental glomerulosclerosis (FSGS) follows congenital or acquired tubulointerstitial alterations such as in Dent's disease, Lowe syndrome, and reflux nephropathy. Failure of adequate regeneration after tubulointerstitial injury, or abnormal tubulogenesis, can disturb intrarenal blood circulation, causing excessive glomerular filtration. The epithelial cell-transforming sequence 2 gene (ECT2) contributes to tight junction function in epithelial cells. Read More

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December 2012

Evolution and prognosis value of intrarenal reflux.

J Pediatr Urol 2011 Dec 14;7(6):638-43. Epub 2010 Oct 14.

Armand-Trousseau Children's Hospital, Pediatric Surgery Department, 26, av. du Dr Arnold Netter, 75012 Paris, France.

Purpose: The aim of this study was to evaluate the prognostic significance of intrarenal reflux (IRR) regarding urinary tract infection (UTI), renal scarring and spontaneous resolution after 3 years of follow up.

Patients And Methods: 33 patients (42 refluxing units) with IRR were compared to 27 children (44 refluxing units) with high-grade vesicoureteral reflux (VUR) without IRR (controls) matched for gender, age and VUR grade. All patients received antibiotic prophylaxis during observation and antireflux surgery was performed in children with recurrent UTI. Read More

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December 2011

The Clinical Significance of Intrarenal Reflux in Voiding Cystourethrography (VCUG).

Korean J Urol 2010 Jan 21;51(1):60-3. Epub 2010 Jan 21.

Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.

Purpose: Intrarenal reflux (IRR) occurs in 3-10% of cases of total reflux and can lead to renal injury, which may eventually result in renal scarring. In this study, we evaluated the clinical importance of IRR detected by voiding cystourethrography and evaluated the relationship between IRR and renal scarring.

Materials And Methods: From January 2002 to May 2008, 50 patients who were diagnosed with vesicoureteral reflux (VUR) and showed IRR in voiding cystourethrography were enrolled. Read More

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January 2010

[Urinary tract infections in children].

Arch Pediatr 2009 Jul 17;16(7):1073-9. Epub 2009 Apr 17.

Service de pédiatrie 2, centre hospitalier universitaire, 2, boulevard du Maréchal-de-Lattre-de-Tassigny, 21000 Dijon, France.

Urinary tract infection (UTI) is relatively frequent in children. The younger the child is, the more symptoms are atypical. UTI is often associated with functional or malformative uropathy, such as vesico-ureteral reflux or obstruction. Read More

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Fetal urinary ascites in a neonate without detectable obstructive uropathy or neurogenic bladder etiology.

J Pediatr Urol 2009 Apr 22;5(2):151-3. Epub 2008 Nov 22.

Cukurova University, Faculty of Medicine, Department of Pediatric Surgery, Adana, Turkey.

Fetal urinary ascites is usually secondary to an obstructive uropathy or neurogenic bladder. We present such a case in the absence of these conditions, but the presence of ipsilateral vesicoureteral reflux with Hutch diverticula. The patient was a 5-day-old boy presenting with distension of the abdomen and impairment of renal function. Read More

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Microalbuminuria in children with vesicoureteral reflux.

Ren Fail 2008 ;30(6):639-43

Institute of Biochemistry, Medical Faculty, University of Nis, Nis, Serbia.

Vesicoureteral reflux (VUR) is a common congenital anomaly of the urinary tract that may be inherited. Reflux of infected urine may cause scarring in susceptible kidneys with the potential to compromise renal function. The aim of the study was to evaluate the possible influence of different grades of VUR on glomerular damage using microalbuminuria as a parameter. Read More

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November 2008

[Doppler US of the urinary system and renal vessels in normal and pathologic conditions].

Nephrol Ther 2008 Oct 9;4(5):350-76. Epub 2008 Jul 9.

Service de radiologie Adultes, hôpital Necker, 149, rue de Sèvres, 75743 Paris, France.

The interest of Doppler ultrasound (US) in urinary tract investigation has dramatically increased during the past 10 years. It can provide useful diagnostic informations in pedicular and intrarenal vascular disorders, some medical nephropathies, in the assessment of renal tumors and urinary tract disorders including urolithiasis, acute obstruction and ureteral reflux. Recent technical improvements including the development of US contrast agents (microbubbles) have contributed to increase the diagnostic accuracy of the technique. Read More

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October 2008

Intrarenal reflux.

Authors:
Selçuk Yüksel

NDT Plus 2008 Jun 6;1(3):188-9. Epub 2008 Feb 6.

Department of Pediatric Nephrology , Bursa Çekirge Children's Hospital , Bursa , Turkey.

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[Vesicoureteral reflux and renal scarring].

Srp Arh Celok Lek 2007 Nov-Dec;135 11-12:679-85

Reflux nephropathy is an acquired focal renal scarring due to the combination of vesicoureteral (VUR) and intrarenal reflux (IRR) associated with urinary tract infections (IUT) and/or permanently high intravesical pressure. Up to 30-60% of children with VUR and a history of symptomatic IUT have renal scarring at the time of their initial studies. The onset of renal scarring usually occurs early in life, usually before age five years and most frequently before three years of age. Read More

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Pharmacological effect on pyeloureteric dynamics with a clinical perspective: a review of the literature.

Urol Res 2006 Dec;34(6):341-50

Department of Urology, Fredericia and Kolding Hospitals, Dronningensgade 97, 7000 Fredericia, Denmark.

We searched to review experimental and clinical trials concerning the capabilities of impacting on the ureteric and pelvic activity by means of pharmacological stimulation. Ureteropyeloscopy may cause high renal pelvic pressure. The normal pressure is in the range of 5-15 mmHg whereas pressure of 410 mmHg has been measured during endoscopy. Read More

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December 2006

[Left flank tumor of fluctuating size in a 5-week-old boy: perirenal urinoma caused by urethral valves].

Klin Padiatr 2006 Sep-Oct;218(5):276-7. Epub 2006 Jul 7.

Zentrum für Kinderheilkunde und Jugendmedizin, Universitätsklinikum Freiburg.

Background: Flank swelling and pseudotumors of the kidney are unusual manifestations of obstructive uropathies in small children. Our case illustrates typical problems and briefly reviews management options.

Case Report: A 5-week-old boy presented with a large, palpable urinoma due to posterior urethral valves. Read More

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December 2006