13,189 results match your criteria interventions bleeding

What is the best mechanical device to clean the teeth in periodontal maintenance patients?

Erfan Shamsoddin

Evid Based Dent 2021 Jan;22(3):91-93

National Institute for Medical Research Development, Tehran, Iran.

Aim This study evaluates the available clinical evidence with regards to the effectiveness of mechanical oral hygiene devices in patients who are in periodontal maintenance.Data sources A structured online search was conducted in PubMed/Medline, Cochrane Central Register of Controlled Trials (CENTRAL) and Embase. All the databases were explored from initiation to October 2019. Read More

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January 2021

Rationale and design of the BA-SCAD (Beta-blockers and Antiplatelet agents in patients with Spontaneous Coronary Artery Dissection) randomized clinical trial.

Rev Esp Cardiol (Engl Ed) 2021 Sep 21. Epub 2021 Sep 21.

Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Departamento de Inmunología, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid, Madrid, Spain.

Introduction Y Objectives: Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome. Most patients are empirically treated with beta-blockers and antiplatelet drugs. The Beta-blockers and Antiplatelet agents in patients with Spontaneous Coronary Artery Dissection (BA-SCAD) is an academic, pragmatic, prospective, randomized, open-label, blinded-endpoint clinical trial, performed under the auspices of the Spanish Society of Cardiology, to assess the efficacy of pharmacological therapy in patients with SCAD. Read More

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September 2021

Feasibility and Safety of an 8 F Angioseal Vascular Closure Device for Closure of Large Bore Impella CP Access.

J Endovasc Ther 2021 Sep 24:15266028211047965. Epub 2021 Sep 24.

Medizinische Klinik und Poliklinik II, Herzzentrum, Universitätsklinikum Bonn, Bonn, Germany.

Purpose: Percutaneous mechanical circulatory support (pMCS) with the Impella device is routinely used in cardiogenic shock and high risk percutaneous coronary interventions (PCI). However, safety and feasibility to close the large bore access (LBA) post-hoc remain a challenge.

Materials And Methods: In patients with planned termination of Impella therapy, corresponding LBA closure was attempted using an undersized AngioSeal device, which was deployed after insertion of a 0. Read More

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September 2021

A comprehensive digital phenotype for postpartum hemorrhage.

J Am Med Inform Assoc 2021 Sep 24. Epub 2021 Sep 24.

Sema4, Stamford, Connecticut, USA.

Objective: We aimed to establish a comprehensive digital phenotype for postpartum hemorrhage (PPH). Current guidelines rely primarily on estimates of blood loss, which can be inaccurate and biased and ignore complementary information readily available in electronic medical records (EMR). Inaccurate and incomplete phenotyping contributes to ongoing challenges in tracking PPH outcomes, developing more accurate risk assessments, and identifying novel interventions. Read More

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September 2021

Surgical and radiological interventions for treating symptomatic extracranial cervical artery dissection.

Cochrane Database Syst Rev 2021 Feb 1;2:CD013118. Epub 2021 Feb 1.

School of Nursing and Midwifery, National University of Ireland Galway, Galway, Ireland.

Background: Cervical artery dissection (CeAD) is a pathological bleed or tear, or both, in the wall of the carotid or vertebral arteries as they course through the neck, and is a leading cause of stroke in young people.

Objectives: To assess the effectiveness of surgical and radiological interventions versus best medical treatment alone for treating symptomatic cervical artery dissection.

Search Methods: We performed comprehensive searches of the Cochrane Stroke Group Trials Register (last searched March 2020), the Cochrane Central Register of Controlled Trials (CENTRAL), 2020, Issue 4, in the Cochrane Library (searched March 2020), MEDLINE (1946 to March 2020) and Embase (1974 to March 2020). Read More

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February 2021

Subcutaneous golimumab induced and maintained clinical response in a child with a biological-experienced steroid-refractory flare of ulcerative colitis: A case report.

Medicine (Baltimore) 2021 Sep;100(38):e27283

Gastroenterology Department, Damascus Hospital, Damascus, Syria.

Introduction: Golimumab is a fully human antitumor necrosis monoclonal antibody that can be administered by either subcutaneous injection or intravenous infusion. Golimumab is approved for the treatment of the adults with rheumatic diseases, and ulcerative colitis, Whereas in children, golimumab is indicated only for the treatment of active polyarticular juvenile idiopathic arthritis. We have written on the off-label use of subcutaneous golimumab, which helped to induce and maintain remission on a low-weight biologically experienced child with steroid-refractory ulcerative colitis flare. Read More

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September 2021

Birth Satisfaction During the Early Months of the COVID-19 Pandemic in the United States.

MCN Am J Matern Child Nurs 2021 Sep 23. Epub 2021 Sep 23.

Elizabeth Mollard, Assistant Professor, University of Nebraska Medical Center, College of Nursing - Lincoln Division, Lincoln, NE. Dr. Mollard can be reached via email at Kevin Kupzyk, Assistant Professor, University of Nebraska Medical Center, College of Nursing - Omaha Division, 985330 Nebraska Medical Center, Omaha, NE.

Abstract: Purpose: The purpose of this study was to describe birth satisfaction in women who gave birth in U.S. hospitals during the earliest months of the COVID-19 pandemic (March-July 2020). Read More

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September 2021

Prevalence of Anemia and Associated Factors Among Term Newborns in Nekemte Specialized Hospital, Western Ethiopia.

J Multidiscip Healthc 2021 17;14:2607-2615. Epub 2021 Sep 17.

Human Anatomy Unit, Department of Biomedical Sciences, Faculty of Medical Science, Institute of Health, Jimma University, Jimma, Oromia, Ethiopia.

Background: Anemia is a global public health problem that affects approximately one-third of the global population. Infants and children are the ones to develop both short-term and long-term devastating complications from anemia. Although anemia is a very big public health concern, newborns, especially in developing countries, are usually overlooked and undiagnosed. Read More

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September 2021

Biliopancreatic and biliary leak after pancreatoduodenectomy treated by percutaneous transhepatic biliary drainage.

HPB (Oxford) 2021 Sep 6. Epub 2021 Sep 6.

Department of Hepato-Pancreato-Biliary Surgery, Regional Academic Cancer Center Utrecht, St. Antonius Hospital Nieuwegein and University Medical Center Utrecht, the Netherlands. Electronic address:

Background: Complementary to percutaneous intra-abdominal drainage, percutaneous transhepatic biliary drainage (PTBD) might ameliorate healing of pancreatic fistula and biliary leakage after pancreatoduodenectomy by diversion of bile from the site of leakage. This study evaluated technical and clinical outcomes of PTBD for this indication.

Methods: All patients undergoing PTBD for leakage after pancreatoduodenectomy were retrospectively evaluated in two tertiary pancreatic centers (2014-2019). Read More

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September 2021

Racial, ethnic and socioeconomic disparities in patients undergoing transcatheter mitral edge-to-edge repair.

Int J Cardiol 2021 Sep 20. Epub 2021 Sep 20.

London Health Sciences Centre, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute of Primary Care and Health Sciences, Keele University, Stoke-on-Trent, United Kingdom. Electronic address:

Background: Transcatheter mitral edge-to-edge repair (TEER) is an increasingly common procedure performed on patients with mitral regurgitation. To assess the impact of race/ethnicity and socioeconomic status on in-hospital complications after TEER.

Methods: Cohort-based observational study using the National Inpatient Sample between October 2013 and December 2018. Read More

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September 2021

Efficacy and safety of elagolix with add-back therapy in women with uterine fibroids and coexisting adenomyosis.

F S Rep 2021 Sep 26;2(3):338-346. Epub 2021 May 26.

Departments of Obstetrics & Gynecology & Surgery, Mayo Clinic and Mayo Medical School, Rochester, Minnesota.

Objective: To determine if coexisting adenomyosis limits the efficacy of elagolix, an oral gonadotropin-releasing hormone antagonist, with hormonal add-back therapy in reducing heavy menstrual bleeding in women with uterine fibroids.

Design: Pooled analysis of two identical, double-blind, randomized, placebo-controlled, 6-month phase 3 trials (Elaris Uterine Fibroids [UF]-1 and UF-2).

Setting: A total of 153 gynecological clinical care settings in the United States and Canada. Read More

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September 2021

Prehospital lactate is Associated with the Need for Blood in Trauma.

Prehosp Emerg Care 2021 Sep 22:1-13. Epub 2021 Sep 22.

University of Pittsburgh, School of Medicine, Department of Emergency Medicine.

Traumatic hemorrhage is the leading cause of preventable death, and its effects are often evident within the first 24 hours of hospital admission. We investigated the relationship between prehospital lactate measurement and administration of hospital blood products and life-saving interventions (LSIs) within 24 hours of hospital admission.: We included trauma patients with recorded prehospital venous lactate transported by a single critical care transport service to a Level I trauma center between 2012 and 2019. Read More

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September 2021

Clusters Across Multiple Domains of Health-Related Quality of Life Reveal Complex Patient Outcomes After Subarachnoid Hemorrhage.

Crit Care Explor 2021 Sep 14;3(9):e0533. Epub 2021 Sep 14.

Institute for Public Health and Medicine, Feinberg School of Medicine of Northwestern University, Chicago, IL.

Patients with aneurysmal subarachnoid hemorrhage (ruptured brain aneurysm) often have reduced health-related quality of life at follow-up in multiple domains (e.g., cognitive function and social function). Read More

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September 2021

Risk factors for stillbirth and early neonatal death: a case-control study in tertiary hospitals in Addis Ababa, Ethiopia.

BMC Pregnancy Childbirth 2021 Sep 21;21(1):641. Epub 2021 Sep 21.

Department of Health Behavior and Health Education, University of Michigan, Ann Arbor, USA.

Background: Ethiopia is a Sub-Saharan country that has made significant improvements in maternal mortality and under-five mortality over the past 15 years. However, the nation continues to have one of the highest rates of perinatal mortality in the entire world with current estimates at 33 deaths per 1000 live births.

Methods: This case-control study was conducted between October 2016 and May 2017 at Tikur Anbessa Hospital and Gandhi Memorial Hospital. Read More

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September 2021

Effectiveness and Safety of Dabigatran in Atrial Fibrillation Patients with Severe Obesity: a Real-World Retrospective Cohort Study.

J Gen Intern Med 2021 Sep 20. Epub 2021 Sep 20.

Department of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA.

Background: Direct oral anticoagulants such as dabigatran are the preferred anticoagulant in treating atrial fibrillation (AF) patients due to their effectiveness and safety. Whether this applies to severely obese patients needs to be determined.

Objective: To compare the effectiveness and safety of dabigatran with warfarin among AF patients with severe obesity. Read More

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September 2021

Safety of Inguinal Hernia Repair in the Elderly with Perioperative Continuation of Antithrombotic Therapy.

Visc Med 2021 Aug 6;37(4):315-322. Epub 2020 Nov 6.

Department of Gastrointestinal Surgery, Hernia Center, West China Hospital, Sichuan University, Chengdu, China.

Introduction: This study aimed to evaluate the safety of an inguinal hernia repair (IHR) under local anesthesia (LA) in the elderly with a perioperative continuation of antithrombotic therapy (AT).

Methods: A total of 120 patients undergoing elective primary IHR between August 2018 and August 2019 at the West China Hospital of China were prospectively studied, among which 60 patients also had coexisting cardiovascular diseases and had a continuation of AT perioperatively (antithrombotic group); the other 60 patients were not on any prior AT (control group). The primary endpoints were intra- and postoperative hemorrhagic complications, the required interventions for complications based on the Clavien-Dindo classification, and postoperative thromboembolic complications. Read More

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Over-the-scope clip as first-line therapy for ulcers with high-risk bleeding stigmata is efficient compared to standard endoscopic therapy.

Endosc Int Open 2021 Oct 16;9(10):E1530-E1535. Epub 2021 Sep 16.

Division of Gastroenterology and Hepatology, Creighton University School of Medicine, Omaha, Nebraska, United States.

Ulcers with high-risk stigmata have significant rebleeding rates despite standard endoscopic therapy. Data on over-the-scope clip (OTSC) for recurrent bleeding is promising but data on first line therapy is lacking. We report comparative outcomes of OTSC as first-line therapy versus standard endoscopic therapy in ulcers with high-risk stigmata. Read More

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October 2021

Prevalence, knowledge and selected associated factors of anaemia among non-pregnant females of reproductive age in a tea estate community in Hantana, Kandy district, Sri Lanka.

Am J Blood Res 2021 15;11(4):438-445. Epub 2021 Aug 15.

Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri-Jayewardenepura Sri Lanka.

Anaemia among non-pregnant females of reproductive age remains a common public health problem globally, as well as in Sri Lanka. The objective of the study was to determine the prevalence of anaemia, asses the knowledge and the associated factors of anaemia among non-pregnant females of reproductive age in a tea estate community in Hantana, Kandy district, Sri Lanka. A descriptive cross-sectional study was conducted among 236 randomly selected non-pregnant females of reproductive age within the tea estate community belonging to two MOH (Medical Officers of Health) areas. Read More

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Efficacy of Melatonin in Animal Models of Subarachnoid Hemorrhage: A Systematic Review and Stratified Meta-Analysis.

Front Neurol 2021 3;12:685731. Epub 2021 Sep 3.

Department of Neurology, Second Xiangya Hospital, Central South University, Changsha, China.

Subarachnoid hemorrhage (SAH) is a severe disease characterized by sudden headache, loss of consciousness, or focal neurological deficits. Melatonin has been reported as a potential neuroprotective agent of SAH. It provides protective effects through the anti-inflammatory effects or the autophagy pathway. Read More

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September 2021

Hematospermia Etiology, Diagnosis, Treatment, and Sexual Ramifications: A Narrative Review.

Sex Med Rev 2021 Sep 16. Epub 2021 Sep 16.

Tulane University School of Medicine, Department of Urology, New Orleans, LA, USA. Electronic address:

Introduction: Hematospermia (HS) is the presence of blood in ejaculatory fluid. It is a rare condition that is historically idiopathic or associated with sexual behavior. Technological advances have identified many of the etiologies behind HS, improving treatment. Read More

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September 2021

Magnet ingestion knows no borders: A threat for Latin American children.

Rev Gastroenterol Mex 2021 Sep 15. Epub 2021 Sep 15.

Departmento de Gastroenteología, Hepatología y Nutrición Pediátrica, University of Miami Miller School of Medicine, Miami, Florida, Estados Unidos. Electronic address:

Introduction And Aims: The ingestion of foreign bodies, such as magnets, is a potentially lethal accident that affects children and is associated with bleeding and gastrointestinal perforation, as well as death. There are no Latin American reports in the literature on cases of magnet ingestion in children. Our aim was to establish whether said ingestion has been seen by pediatric endoscopists and gastroenterologists in Latin America, to determine the scope of that potential threat in their patient populations. Read More

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September 2021

ACTION-1: study protocol for a randomised controlled trial on ACT-guided heparinization during open abdominal aortic aneurysm repair.

Trials 2021 Sep 19;22(1):639. Epub 2021 Sep 19.

Department of Vascular Surgery, Dijklander ziekenhuis, Maelsonstraat 3, 1624, NP, Hoorn, The Netherlands.

Background: Heparin is used worldwide for 70 years during all non-cardiac arterial procedures (NCAP) to reduce thrombo-embolic complications (TEC). But heparin also increases blood loss causing possible harm for the patient. Heparin has an unpredictable effect in the individual patient. Read More

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September 2021

Techniques and Outcomes of Transjugular Intrahepatic Porto Systemic Shunting in infants with Budd Chiari Syndrome.

J Vasc Interv Radiol 2021 Sep 14. Epub 2021 Sep 14.

Department of Vascular and Interventional Radiology, Jaslok Hospital and Research Centre, Mumbai, India.

Purpose: To describe the technical aspects, feasibility, and outcomes in children with Budd Chiari Syndrome (BCS) undergoing transjugular intrahepatic portosystemic shunt (TIPS) creation during infancy.

Materials And Methods: Retrospective review of infants diagnosed with BCS between 2012 - 2018 undergoing TIPS creation was performed. Eight infants (5 males) underwent TIPS creation (7 for refractory ascites and 1 for refractory variceal bleeding) during the study period. Read More

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September 2021

Sex Differences in Trends and In-Hospital Outcomes Among Patients With Critical Limb Ischemia: A Nationwide Analysis.

J Am Heart Assoc 2021 Sep 17;10(18):e022043. Epub 2021 Sep 17.

Department of Medicine Weill Cornell Medicine-Qatar Doha Qatar.

Background Critical limb ischemia (CLI) represents the most severe form of peripheral artery disease and is associated with significant mortality and morbidity. Contemporary data comparing the sex differences in trends, revascularization strategies, and in-hospital outcomes among patients with CLI are scarce. Methods and Results Using the National Inpatient Sample database years 2002 to 2015, we identified hospitalizations for CLI. Read More

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September 2021

Submassive Pulmonary Embolism Complicating Small Bowel Obstruction.

Cureus 2021 Aug 13;13(8):e17162. Epub 2021 Aug 13.

Interventional Cardiology, Loyola University Medical Center, Maywood, USA.

The evaluation of patients with pulmonary embolism (PE) requires a comprehensive approach that assesses physical and laboratory exam findings, interprets varying imaging modalities, and selects appropriate treatment strategies. Comorbidities can complicate treatment and influence physicians to make difficult management decisions. In this case report, we present a patient with a small bowel obstruction complicated by submassive intermediate high-risk PE. Read More

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China Stroke Registry for Patients With Traditional Chinese Medicine (CASES-TCM): Rationale and Design of a Prospective, Multicenter, Observational Study.

Front Pharmacol 2021 31;12:743883. Epub 2021 Aug 31.

Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Given the complexity of stroke treatment and the current widespread use of traditional Chinese medicine (TCM) in the absence of robust, large, long-term effectiveness and safety studies, and the lack of nationwide epidemiology and clinical characteristics of patients with stroke receiving TCM treatment, the acquisition of data from longitudinal cohorts is essential. We intend to generate the major clinical characteristics of patients with stroke who receive TCM treatment and to investigate the effectiveness and safety of TCM in the Chinese population. The China Stroke Registry for Patients with Traditional Chinese Medicine (CASES-TCM) study is a prospective, multicenter, observational disease registry aiming to register 20,000 hospitalized patients. Read More

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Cost-Effectiveness and Cost-Utility Analysis of the Use of Clopidogrel and Pantoprazole in Comparison with Clopidogrel and Omeprazole for the Secondary Prevention of Myocardial Infarction in Iran.

J Res Pharm Pract 2021 Apr-Jun;10(2):90-95. Epub 2021 Aug 3.

Department of Clinical Pharmacy and Pharmacy Practice, Isfahan University of Medical Sciences, Isfahan, Iran.

Objective: Gastrointestinal bleeding, a side effect of clopidogrel, is usually prevented by proton-pump inhibitors (PPIs). Due to omeprazole's inhibitory effects on the liver enzyme CYP2C19, its concomitant use with clopidogrel is argued to increase the risk of myocardial infarction (MI) recurrence, as CYP2C19 activates clopidogrel. Pantoprazole as an alternative PPI has shown no inhibitory effect on CYP2C19. Read More

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The intersection of bronchoscopy and extracorporeal membrane oxygenation.

J Thorac Dis 2021 Aug;13(8):5176-5182

Division of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin, Madison, WI, USA.

Central airway obstruction (CAO), which results from malignant, benign or iatrogenic etiologies, causes significant morbidity and mortality and can be seen in both the pediatric and adult patient population. Patients frequently present to the hospital with dyspnea, stridor, and respiratory distress, indicating impending respiratory failure. Heliox is used to help alleviate symptoms while procedural planning takes place. Read More

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Foreign body aspiration.

J Thorac Dis 2021 Aug;13(8):5159-5175

Department of Respiratory Medicine, Dr. RML Hospital & Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, India.

The clinical manifestations of foreign body (FB) aspiration can range from an asymptomatic presentation to a life-threatening emergency. Patients may present with acute onset cough, chest pain, breathlessness or sub-acutely with unexplained hemoptysis, non-resolving pneumonia and at times, as an incidental finding on imaging. Patients with iatrogenic FB such as an aspirated broken tooth during difficult intubation or a broken instrument are more common scenarios in the intensive care unit (ICU). Read More

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Management of life-threatening hemoptysis in the ICU.

J Thorac Dis 2021 Aug;13(8):5139-5158

Division of Pulmonary and Critical Care Medicine, Section of Interventional Pulmonology, University of Maryland School of Medicine, Baltimore, MD, USA.

Life-threatening hemoptysis is commonly encountered in the ICU and its management can be challenging even for experienced clinicians. Depending on the etiology and severity, one can tailor the treatment modality and therapeutic intervention(s). The grading of severity of hemoptysis varies greatly in the literature; however, unlike hemorrhage in other scenarios, small amounts of blood can significantly impair oxygenation and ventilation leading to cardiovascular collapse. Read More

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