10,764 results match your criteria interventions abdominal


Efficacy and safety of Qingre-Chushi therapies in active ulcerative colitis: A network meta-analysis.

PLoS One 2021 20;16(9):e0257599. Epub 2021 Sep 20.

Institute of Gastroenterology, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.

Background: Ulcerative colitis (UC) is a chronic inflammatory disease with an increasing incidence in the world. Qingre-Chushi therapies (QC) can alleviate clinical symptoms. Therefore, a network meta-analysis was conducted to systematically evaluate the efficacy and safety of QC in the treatment of active UC patients. Read More

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September 2021

Excess Body Weight and Abdominal Hernia.

Visc Med 2021 Aug 28;37(4):246-253. Epub 2021 Apr 28.

Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany.

Background: Obese patients have an increased incidence of ventral hernias; in over 50% of these cases, patients are symptomatic. At the same time, morbid obesity is a disease of epidemic proportions. The combination of symptomatic hernia and obesity is a challenge for the treating surgeon, because the risk of perioperative complications and recurrence increases with increasing BMI. Read More

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Trauma Scores and Their Prognostic Value for the Outcome Following Pediatric Polytrauma.

Front Pediatr 2021 3;9:721585. Epub 2021 Sep 3.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.

The management and prognostic assessment of pediatric polytrauma patients can pose substantial challenges. Trauma scores developed for adults are not universally applicable in children. An accurate prediction of the severity of trauma and correct assessment of the necessity of surgical procedures are important for optimal treatment. Read More

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September 2021

Peritoneal mesothelioma with invasion of the urinary bladder 20 years post radiation therapy for colon adenocarcinoma.

J Surg Case Rep 2021 Sep 15;2021(9):rjab392. Epub 2021 Sep 15.

Department of Urology, Mater Dei Hospital, Msida, Malta.

We present the case of a 66-year-old male with a history of iatrogenic bladder injury and radiation therapy for colon adenocarcinoma 20 years prior. A computed tomography of the thorax, abdomen and pelvis, reported a presacral mass with invasion to the bladder, ureters and lymph nodes. An initial bladder biopsy was histologically inconclusive. Read More

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September 2021

Effectiveness of a complex psychosocial intervention to reduce metabolic syndrome in psychiatric outpatients with severe/persistent mental illness.

Curr Psychol 2021 Sep 12:1-10. Epub 2021 Sep 12.

Waypoint Research Institute, Waypoint Centre for Mental Health Care, 500 Church Street, Penetanguishene, Ontario L9M 1G3 Canada.

The prevalence of metabolic syndrome among individuals with severe mental illness is considerably higher than in the general population, contributing to the 15-20-year shorter life expectancy of this client population. The aim of this pilot study was to evaluate the effectiveness of a novel, complex psychosocial program to reduce metabolic syndrome. Members of both the intervention (n = 78) and control (n = 31) group were psychiatric outpatients with severe/persistent mental illness struggling with one or more symptoms of metabolic syndrome. Read More

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September 2021

Perforated appendicitis induced by pembrolizumab: a case report and review of the literature.

Anticancer Drugs 2021 Sep 17. Epub 2021 Sep 17.

Division of Medical Oncology and Hematopoietic Cell Transplant Unit, Department of Medicine Department of Gastroenterology Department of Surgery Pathology Department Molecular Pathology Unit, 'Metaxa' Cancer Hospital, Piraeus, Greece.

Monoclonal antibodies against programmed cell death protein 1 (PD-1) and PD-1 ligand 1 (PD-L1) are the main representatives in the field of immunotherapy and their indications are constantly increasing in medical oncology and hematology during the last decade. They are associated with long-lasting responses and an acceptable toxicity profile, although they may infrequently cause life-threatening complications requiring prolonged hospitalization or urgent interventions. With the current report, we present the case of a 75-year-old woman diagnosed with stage IV lung adenocarcinoma, who developed acute abdominal pain without preceding symptomatology while on pembrolizumab-pemetrexed maintenance treatment. Read More

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September 2021

ACTION-1: study protocol for a randomised controlled trial on ACT-guided heparinization during open abdominal aortic aneurysm repair.

Trials 2021 Sep 19;22(1):639. Epub 2021 Sep 19.

Department of Vascular Surgery, Dijklander ziekenhuis, Maelsonstraat 3, 1624, NP, Hoorn, The Netherlands.

Background: Heparin is used worldwide for 70 years during all non-cardiac arterial procedures (NCAP) to reduce thrombo-embolic complications (TEC). But heparin also increases blood loss causing possible harm for the patient. Heparin has an unpredictable effect in the individual patient. Read More

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September 2021

Clinical relevance of Closed-Incision Negative Pressure Therapy (ciNPT) for SSI-risk reduction in vascular surgery through a groin incision.

Ann Vasc Surg 2021 Sep 16. Epub 2021 Sep 16.

Department of Vascular Surgery Hagaziekenhuis, The Hague.

Objective: Vascular surgery, especially lower limb revascularization surgery, has one of the highest rates of surgical complications, predominantly surgical site infections (SSI). Resulting in a significant burden of additional costs due to longer hospital stays, re-admissions and re-interventions, mainly attributable to deep incisional SSIs. Using closed incisional negative pressure therapy (ciNPT) is a relatively new technology in the postoperative management surgical wounds, aiming to reduce surgical wound complications. Read More

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September 2021

Perioperative goal-directed therapy in high-risk abdominal surgery. A multicenter randomized controlled superiority trial.

J Clin Anesth 2021 Sep 15;75:110506. Epub 2021 Sep 15.

Department of Anesthesiology, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address:

Study Objective: The potential of perioperative goal-directed therapy (PGDT) to improve outcome after high-risk abdominal surgery remains subject of debate. In particular, there is a need for large, multicenter trials focusing on relevant patient outcomes to confirm the evidence found in small, single center studies including minor complications in their composite endpoints. The present study therefore aims to investigate the effect of an arterial waveform analysis based PGDT algorithm on the incidence of major complications including mortality after high-risk abdominal surgery. Read More

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September 2021

Non-pharmacological Treatment for Children With Functional Constipation: A Systematic Review and Meta-analysis.

J Pediatr 2021 Sep 15. Epub 2021 Sep 15.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Department of Pediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands.

Objective: To evaluate the effectiveness and safety of non-pharmacological interventions for the treatment of childhood functional constipation functional constipation.

Study Design: Randomized controlled trials (RCTs) evaluating non-pharmacological treatments in children with functional constipation which reported at least one outcome of the core outcome set for children with functional constipation.

Results: 52 RCTs were included with 4668 children, aged between 2 weeks and 18 years, of whom 47% were females. Read More

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September 2021

Abdominal cocoon syndrome, a case report of a rare disease entity causing intestinal obstruction.

Int J Surg Case Rep 2021 Sep 13;87:106401. Epub 2021 Sep 13.

Alzaiem Alazhari University - Department of Surgery, Sudan.

Introduction And Importance: Abdominal cocoon syndrome is a rare condition characterized by small bowel encapsulation by a fibrous membrane or a cocoon-like sac. It is an uncommon cause of intestinal obstruction. Less than 300 cases have been reported from all over the world. Read More

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September 2021

Why use nutraceutical strategies for the Irritable Bowel Syndrome.

Curr Med Chem 2021 Sep 16. Epub 2021 Sep 16.

Dept Systems Medicine, Policlinico Tor Vergata (PTV) Foundation, Rome, Italy.

Irritable bowel syndrome (IBS) is a chronic functional bowel disorder, often stress-related, identified by many abdominal symptoms, the most important of which is the chronic visceral abdominal pain. Therefore, IBS commonly impairs the quality of life of patients, moreover it is frequently linked to depressive and anxiety symptoms. The treatment of IBS primarily focuses on symptoms relief. Read More

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September 2021

Is the rural population of Puducherry district healthy in terms of the burden of non-communicable diseases? Findings from a cross-sectional analytical survey.

J Postgrad Med 2021 Sep 16. Epub 2021 Sep 16.

Department of Preventive and Social Medicine, JIPMER, Puducherry, India.

Introduction: Epidemiological transition remains a key contributor to the rising prevalence of non-communicable diseases (NCDs) across developing nations. Population-specific NCD risk factors estimates derived using World Health Organization (WHO) 'STEP-wise approach' are crucial for devising evidence-based public health interventions to combat NCDs.

Objective: To estimate the prevalence of behavioral and biological risk factors for NCDs among the rural adult population of Puducherry district in India. Read More

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September 2021

Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study.

BMJ Open Diabetes Res Care 2021 Sep;9(1)

NIDDK, National Institutes of Health, Bethesda, Maryland, USA

Introduction: Uncertainties exist on whether the main determinant of abnormal glucose tolerance (Abnl-GT) in Africans is β-cell failure or insulin resistance (IR). Therefore, we determined the prevalence, phenotype and characteristics of Abnl-GT due to β-cell failure versus IR in 486 African-born blacks (male: 64%, age: 38±10 years (mean±SD)) living in America.

Research Design And Methods: Oral glucose tolerance test were performed. Read More

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September 2021

How to manage irritable bowel syndrome in children.

Acta Paediatr 2021 Sep 15. Epub 2021 Sep 15.

KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Aim: This paper discusses the risk factors and management of paediatric irritable bowel syndrome (IBS), with a focus on the role of the gastro-intestinal microbiome.

Methods: English articles of interest published in PubMed and Google Scholar were searched using subject heading and key words of interest.

Results: Only few randomized controlled trials on the management of IBS in children have been published. Read More

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September 2021

Effect of Hernia Mesh Weights on Postoperative Patient-Related and Clinical Outcomes After Open Ventral Hernia Repair: A Randomized Clinical Trial.

JAMA Surg 2021 Sep 15. Epub 2021 Sep 15.

Cleveland Clinic Center for Abdominal Core Health, Digestive Disease and Surgery Institute, The Cleveland Clinic Foundation, Cleveland, Ohio.

Importance: Although multiple versions of polypropylene mesh devices are currently available on the market for hernia repair, few comparisons exist to guide surgeons as to which device may be preferable for certain indications. Mesh density is believed to impact patient outcomes, including rates of chronic pain and perception of mesh in the abdominal wall.

Objective: To examine whether medium-weight polypropylene is associated with less pain at 1 year compared with heavy-weight mesh. Read More

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September 2021

Intraoperative cone-beam and slot-beam CT: 3D image quality and dose with a slot collimator on the O-arm imaging system.

Med Phys 2021 Sep 14. Epub 2021 Sep 14.

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

Purpose: To characterize the 3D imaging performance and radiation dose for a prototype slot-beam configuration on an intraoperative O-arm™ Surgical Imaging System (Medtronic Inc., Littleton MA) and identify potential improvements in soft-tissue image quality for surgical interventions.

Methods: A slot collimator was integrated with the O-arm system for slot-beam axial CT. Read More

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September 2021

Short-term outcomes of open surgical abdominal aortic aneurysm repair from the Dutch Surgical Aneurysm Audit.

BJS Open 2021 Sep;5(5)

Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands.

Background: The sharp decrease in open surgical repair (OSR) for abdominal aortic aneurysm (AAA) has raised concerns about contemporary postoperative outcomes. The study was designed to analyse the impact of complications on clinical outcomes within 30 days following OSR.

Methods: Patients who underwent OSR for intact AAA registered prospectively between 2016 and 2019 in the Dutch Surgical Aneurysm Audit were included. Read More

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September 2021

Aetiology and risk factors of bacterial gastroenteritis among febrile outpatients at the Dschang District Hospital, West Region of Cameroon: a cross-sectional study.

BMJ Open 2021 Sep 13;11(9):e045965. Epub 2021 Sep 13.

Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, West Region, Cameroon

Objectives: To investigate the bacterial aetiologies and associated risk factors of gastroenteritis among typhoid suspected cases.

Design: Cross-sectional study.

Setting: This study was conducted at Dschang District Hospital of the Menoua Division, West Region of Cameroon, between April-November 2019 and June 2020. Read More

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September 2021

Combination treatment with trastuzumab and crizotinib in metastatic gastric cancer harboring Her-2 amplification and c-MET amplification: A case report.

Authors:
Mingsheng Liu

Medicine (Baltimore) 2021 Sep;100(36):e27017

Department of Anus and Intestine Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, Zhejiang, China.

Rationale: Metastatic gastric cancer patients with poor eastern cooperative oncology group performance status (PS) (≥3) were lack of effective anti-tumor strategies. They always lived with poor PS, severe and multiple symptoms, and usually resulted in extremely limited survival time. Herein, we reported a patient diagnosed with gastric cancer metastasized to multiple bones, along with lymphangitis carcinomatosa in lungs, harboring Her-2 and c-MET amplification with poor PS, positively responded to combinational therapy with trastuzumab and crizotinib. Read More

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September 2021

Preoperative Serum Vedolizumab Levels Do Not Impact Postoperative Outcomes in Inflammatory Bowel Disease.

Dis Colon Rectum 2021 Oct;64(10):1259-1266

Division of Colorectal Surgery, Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles California.

Background: Vedolizumab has been proposed to lead to fewer postoperative complications because of its gut specificity. Studies, however, suggest an increased risk of surgical site infections, yet the data are conflicting.

Objective: This study aimed to assess the effect of vedolizumab drug levels on postoperative outcomes in patients undergoing major abdominal surgery for IBD. Read More

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October 2021

Genetic and Epidemiological Similarities, and Differences Between Postoperative Intraperitoneal Adhesion Development and Other Benign Fibro-proliferative Disorders.

Reprod Sci 2021 Sep 13. Epub 2021 Sep 13.

Department of Obstetrics and Gynecology, Augusta University, 1120 15th Street, CJ-1036, Augusta, GA, 30912, USA.

Intraperitoneal adhesions complicate over half of abdominal-pelvic surgeries with immediate, short, and long-term sequelae of major healthcare concern. The pathogenesis of adhesion development is similar to the pathogenesis of wound healing in all tissues, which if unchecked result in production of fibrotic conditions. Given the similarities, we explore the published literature to highlight the similarities in the pathogenesis of intra-abdominal adhesion development (IPAD) and other fibrotic diseases such as keloids, endometriosis, uterine fibroids, bronchopulmonary dysplasia, and pulmonary, intraperitoneal, and retroperitoneal fibrosis. Read More

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September 2021

Management of solitary cecum diverticulitis - Single-Center Experience.

Pol Przegl Chir 2021 Mar;93(4):15-20

Department of Biostatistics, Sakarya University Faculty of Medicine, Sakarya, Turkey.

<b> Objective: </b> Cecal diverticulitis may be encountered as a real etiological factor in 1/300 appendectomies. Differential diagnosis of acute appendicitis and cecal diverticulitis is crucial because of the different treatment methods. Our aim is to reveal the importance of distinguishing acute appendicitis from cecal diverticulitis. Read More

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Disparities in Deceased Organ Donor Research Authorization: Experience at One Organ Procurement Organization and Call for National Conversations.

Kidney Int Rep 2021 Sep 26;6(9):2331-2337. Epub 2021 Jun 26.

University of Nebraska Medical Center, Omaha, Nebraska, USA.

Introduction: Research with deceased donor organs can provide an important platform for studying interventions to improve organ use and outcomes after authorization from the next-of-kin (NOK) or before death by the decedent (i.e., first-person authorization [FPA]). Read More

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September 2021

Short-Term Re-intervention of Endovascular Abdominal Aortic Aneurysm Repair.

Cureus 2021 Aug 1;13(8):e16810. Epub 2021 Aug 1.

Department of General Surgery, West Hertfordshire Hospitals NHS Trust, Watford, GBR.

Background and aim Endovascular aneurysm repair (EVAR) has revolutionized the management of abdominal aortic aneurysm (AAA). The re-intervention rate following EVAR has been a subject of debate in many studies. The study aims to evaluate the short-term outcomes in terms of the early (four-year) re-intervention rate following EVAR at our centre and compare it to the average re-intervention rate of the main studies assessed by the National Institute of Health and Care Excellence (NICE). Read More

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A feasibility study investigating the utility of a point-of-care rapid immunoassay for detecting septic peritoneal effusion in dogs.

J Vet Emerg Crit Care (San Antonio) 2021 Sep 12. Epub 2021 Sep 12.

Critical Care Department, BluePearl Veterinary Partners, Queens, New York, USA.

Objective: To determine the sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), and accuracy of a point-of-care urine bacterial rapid immunoassay (RIA) for a diagnosis of septic peritonitis, compared to more traditional diagnostic tools, such as cytology and bacterial culture.

Design: Prospective, cross-sectional feasibility study conducted from October 2016 to June 2017.

Setting: Four locations within a private practice referral hospital. Read More

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September 2021

Complications after transesophageal echocardiogram in pediatric patients with gastrostomy tube and/or Nissen fundoplication.

Echocardiography 2021 Sep 12. Epub 2021 Sep 12.

Heart Center, Nationwide Children's Hospital, Columbus, Ohio, USA.

Introduction: Transesophageal echocardiography (TEE) is frequently used in children with and without congenital heart disease when transthoracic echocardiography is inadequate for visualizing cardiac structures. Recent guidelines state relative contraindications of TEE include post-gastrostomy tube (GT) or Nissen fundoplication surgery. No data exist documenting the incidence of complications in this population after a TEE. Read More

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September 2021

Care burden and outcome of the surgical management of ulcerative colitis: A retrospective analysis of the last 20 years in a tertiary hospital in Spain.

Cir Esp 2021 Sep 8. Epub 2021 Sep 8.

Servicio de Cirugía General y Digestiva, Unidad de Cirugía Colorrectal, Hospital Universitario Donostia, Instituto Biodonostia, Spain.

Aim: To analyze the surgical burden of UC care in the last two decades, analyzing the characteristics of the patients, surgical indications along with the short and long-term results.

Method: Single-center retrospective cohort analysis of UC patients undergoing abdominal and anorectal surgery between January 2000 and December 2020. The care burden, clinical data and results were analyzed according to distribution by decades. Read More

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September 2021

Pathways linking abdominal obesity to poor memory function: Explore the mediating role of hypertension and depressive symptoms.

J Affect Disord 2021 Sep 4;295:492-497. Epub 2021 Sep 4.

Department of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao, China. Electronic address:

Background: The negative effect of abdominal obesity on cognitive function has been widely reported, especially on memory function, however, it is unclear how the effect is mediated. We aim to investigate the mediating role of hypertension and depressive symptoms.

Methods: Data were collected from wave 6 (2012-2013) of the English Longitudinal Study of Ageing (ELSA). Read More

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September 2021

Incidental Adrenal Masses: Adherence to Guidelines and Methods to Improve Initial Follow-Up, A Systematic Review.

J Surg Res 2021 Sep 7;269:18-27. Epub 2021 Sep 7.

Boston University School of Medicine, Boston, Massachusetts; Boston Medical Center, Department of Surgery, Boston Massachusetts. Electronic address:

Objective: Incidental adrenal masses (IAMs) are detected in approximately 1%-2% of abdominal computed tomography (CT) scans. Recent estimates suggest that more than 70-million relevant CT scans are performed annually in the United States; thus, IAMs represent a significant clinical entity. Most clinical guidelines recommend an initial follow-up evaluation that includes imaging and biochemical testing after index IAM detection. Read More

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September 2021