2,351 results match your criteria intervals p-value


Income level and antibiotic misuse: a systematic review and dose-response meta-analysis.

Eur J Health Econ 2021 Nov 30. Epub 2021 Nov 30.

Department of Preventive Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain.

Objectives: To quantify the association between income and antibiotic misuse including unprescribed use, storage of antibiotics and non-adherence.

Methods: We identified pertinent studies through database search, and manual examination of reference lists of selected articles and review reports. We performed a dose-response meta-analysis of income, both continuous and categorical, in relation to antibiotic misuse. Read More

View Article and Full-Text PDF
November 2021

A Meta-Analysis and Meta-Regression of Frequency and Risk Factors for Poststroke Complex Regional Pain Syndrome.

Medicina (Kaunas) 2021 Nov 11;57(11). Epub 2021 Nov 11.

Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan.

This article aimed to investigate the risk factors for poststroke complex regional pain syndrome (CRPS). We searched electronic databases including PubMed, Medline, Web of Science, Cochrane Library, and Embase up to 27 October 2021. We enrolled analytical epidemiological studies comprising cohort, case-control, and cross-sectional studies. Read More

View Article and Full-Text PDF
November 2021

Physical activity reduces the risk of pneumonia: systematic review and meta-analysis of 10 prospective studies involving 1,044,492 participants.

Geroscience 2021 Nov 25. Epub 2021 Nov 25.

Department of Medicine, Central Finland Health Care District, Jyväskylä, Finland.

The beneficial effects of regular physical activity in promoting health and preventing chronic diseases are well documented. The relationship between regular physical activity and the risk of pneumonia is uncertain. We aimed to evaluate the magnitude and specificity of the prospective association between regular physical activity and the risk of pneumonia using a systematic review and meta-analysis of published observational cohort studies in general populations. Read More

View Article and Full-Text PDF
November 2021

Relationship Between Red Blood Cell Distribution Width and All-Cause Mortality in Disseminated Intravascular Coagulation Patients: A Retrospective Analysis.

Int J Gen Med 2021 16;14:8301-8309. Epub 2021 Nov 16.

Department of Hematology, First People's Hospital of Changde City, Changde, Hunan, People's Republic of China.

Purpose: Studies regarding death risk factors of disseminated intravascular coagulation (DIC) patients were limited. We conducted this study to investigate whether red blood cell distribution width (RDW) was independently related to all-cause mortality of DIC patients.

Methods: We used data from the Medical Information Mart for Intensive Care III version 1. Read More

View Article and Full-Text PDF
November 2021

Toxoplasma infection and risk of epilepsy: A case-control study of incident patients.

Microb Pathog 2021 Nov 20;161(Pt B):105302. Epub 2021 Nov 20.

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Electronic address:

We performed an age matched case-control study of incident epileptic patients to assess the relationship between Toxoplasma gondii seropositivity and epilepsy. Cases were 94 newly diagnosed patients (mean age, 36.7 ± 15. Read More

View Article and Full-Text PDF
November 2021

Comparison of the efficacy of microneedling versus CO fractional laser to treat striae alba: A randomized clinical trial.

Dermatol Ther 2021 Nov 18:e15212. Epub 2021 Nov 18.

Molecular Dermatology Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.

Striae distensae (SD) are common skin conditions that have posed a significant challenge regarding their assessment and treatment. The present study aimed to evaluate the efficacy of microneedling in comparison to fractional CO laser therapy. Similar striae were selected and photographed. Read More

View Article and Full-Text PDF
November 2021

Minimally invasive anterolateral approach versus lateral transmuscular approach for total hip arthroplasty: A systematic review and meta-analysis.

Surgeon 2021 Nov 15. Epub 2021 Nov 15.

Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, Chiba, 299-0111, Japan.

Background: Total hip arthroplasty (THA) using a minimally invasive (MI) approach is a commonly performed procedure, and several approaches are now being used clinically. The MI anterolateral (MIAL) approach is one of the MI approaches used in clinical practice. Whether the MIAL approach is superior to non-MI approaches remains controversial. Read More

View Article and Full-Text PDF
November 2021

Impact of malocclusion severity on the quality of life of non-white adolescents.

Cien Saude Colet 2021 15;26(suppl 3):5233-5240. Epub 2021 Nov 15.

Programa de Pós-Graduação em Odontologia, Fundação Hermínio Ometto (FHO). Av. Dr. Maximiliano Baruto 500, Araras. 13607-339 São Paulo SP Brasil.

The aim of this study was to evaluate the impact of malocclusion severity on the oral health-related quality of life (OHRQoL) of non-white adolescents. A cross-sectional study was conducted with 585 non-white Brazilian adolescents (12-15 years). The Dental Aesthetic Index (DAI) was used for the clinical assessment of malocclusion and Oral Health Impact Profile (OHIP-14) on OHRQoL. Read More

View Article and Full-Text PDF
November 2021

Prospective assessment of vacuum deliveries from midpelvic station in a tertiary care university hospital: Frequency, failure rates, labor characteristics and maternal and neonatal complications.

PLoS One 2021 16;16(11):e0259926. Epub 2021 Nov 16.

Division of Gynaecology and Obstetrics, Oslo University Hospital, Oslo, Norway.

Background: Midpelvic vacuum extractions are controversial due to reports of increased risk of maternal and perinatal morbidity and high failure rates. Prospective studies of attempted midpelvic vacuum outcomes are scarce. Our main aims were to assess frequency, failure rates, labor characteristics, maternal and neonatal complications of attempted midpelvic vacuum deliveries, and to compare labor characteristics and complications between successful and failed midpelvic vacuum deliveries. Read More

View Article and Full-Text PDF
November 2021

Smoking and XPC Gene Polymorphism Interact to Modulate the Risk of Oral Cancer.

J Maxillofac Oral Surg 2021 Dec 27;20(4):607-611. Epub 2020 Feb 27.

Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow, Uttar Pradesh India.

Purpose: Oral cancer is the most common cancer among the Indian men and the second most common cancer among the Indian women. Such high incidence of oral cancer in India is due to consumption of tobacco in different form including smoking of cigarette. Smoke of tobacco contains different carcinogens which causes DNA damage. Read More

View Article and Full-Text PDF
December 2021

Comparative Evaluation of Reconstructive Methods in Oral Submucous Fibrosis.

J Maxillofac Oral Surg 2021 Dec 23;20(4):597-606. Epub 2021 Jan 23.

Department of Oral and Maxillofacial Surgery, PMNM Dental College and Hospital, Navanagar, Bagalkot, Karnataka India.

Background: Oral submucous fibrosis is a chronic, progressive, scarring, precancerous condition of oral mucosa which on progression causes severe trismus.

Aim And Objectives: To compare and evaluate the efficiency of buccal fat pad, platysmal mucocutaneous flap, nasolabial flap, collagen membrane graft, split thickness skin graft and temporoparietal fascia in reconstruction of surgical defect created by excision of fibrous bands in oral submucous fibrosis.

Results: After 6 months of follow-up, the interincisal mouth opening was 40. Read More

View Article and Full-Text PDF
December 2021

Increased COVID-19 Testing Rates Following Combined Door-to-Door and Mobile Testing Facility Campaigns in Oslo, Norway, a Difference-in-Difference Analysis.

Int J Environ Res Public Health 2021 Oct 21;18(21). Epub 2021 Oct 21.

Centre for Epidemic Interventions Research, Norwegian Institute of Public Health, 0213 Oslo, Norway.

High testing rates limit COVID-19 transmission. Attempting to increase testing rates, Stovner District in Oslo, Norway, combined door-to-door campaigns with easy access testing facilities. We studied the intervention's impact on COVID-19 testing rates. Read More

View Article and Full-Text PDF
October 2021

Evaluation of hemodynamic changes during laparoscopic cholecystectomy by transthoracic echocardiography.

J Anaesthesiol Clin Pharmacol 2021 Jul-Sep;37(3):436-442. Epub 2021 Oct 12.

Department of Anaesthesiology and Critical Care, Pt. BD Sharma University of Health Sciences, Rohtak, Haryana, India.

Background And Aims: The purpose of this study was to prospectively examine the effects of pneumoperitoneum and the reverse Trendelenburg position on cardiac hemodynamics during laparoscopic cholecystectomy using transthoracic echocardiography (TTE).

Material And Methods: In this prospective observational study, after institutional review board clearance, forty patients of either sex of ASA I-II status undergoing laparoscopic cholecystectomy were enrolled in the study. Changes in cardiac output, stroke volume, and ejection fraction were recorded using TTE at different time intervals: Preoperatively, before creation of pneumoperitoneum, 5 min after creation of pneumoperitoneum, and 5 min after setting the operative reverse Trendelenburg position with legs at the level of the hips. Read More

View Article and Full-Text PDF
October 2021

Maternal sociodemographic characteristics, early pregnancy behaviours, and livebirth outcomes as congenital heart defects risk factors - Northern Ireland 2010-2014.

BMC Pregnancy Childbirth 2021 Nov 10;21(1):759. Epub 2021 Nov 10.

School of Psychology, Ulster University, Coleraine, UK.

Background: Congenital Heart Defects (CHD) is the most commonly occurring congenital anomaly in Europe and a major paediatric health care concern. Investigations are needed to enable identification of CHD risk factors as studies have given conflicting results. This study aim was to identify maternal sociodemographic characteristics, behaviours, and birth outcomes as risk factors for CHD. Read More

View Article and Full-Text PDF
November 2021

PASI vs PO-PASI: Patient-Oriented PASI (PO-PASI) is comparable to clinician score PASI.

Australas J Dermatol 2021 Nov 10. Epub 2021 Nov 10.

Medical School, The University of Auckland, Auckland, New Zealand.

This comparative observational study aimed to validate an online Patient-oriented Psoriasis Area and Severity Index (PO-PASI) by comparing it against the Psoriasis Area and Severity Index (PASI), of 97 adult participants with chronic plaque psoriasis. Pearson's correlation coefficient of 0.866 (P-value = 0. Read More

View Article and Full-Text PDF
November 2021

Development of the Wheat Practical Haplotype Graph Database as a Resource for Genotyping Data Storage and Genotype Imputation.

G3 (Bethesda) 2021 Nov 9. Epub 2021 Nov 9.

Department of Plant Pathology, Kansas State University, Manhattan, KS, 66506, USA.

To improve the efficiency of high-density genotype data storage and imputation in bread wheat (Triticum aestivum L.), we applied the Practical Haplotype Graph (PHG) tool. The wheat PHG database was built using whole-exome capture sequencing data from a diverse set of 65 wheat accessions. Read More

View Article and Full-Text PDF
November 2021

Occupational factors and miscarriages in the US fire service: a cross-sectional analysis of women firefighters.

Environ Health 2021 Nov 8;20(1):116. Epub 2021 Nov 8.

Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N Martin Ave, Tucson, AZ, 85724, USA.

Background: Evidence from previous studies suggests that women firefighters have greater risk of some adverse reproductive outcomes. The purpose of this study was to investigate whether women firefighters had greater risk of miscarriage compared to non-firefighters and whether there were occupational factors associated with risk of miscarriage among firefighters.

Methods: We studied pregnancies in the United States fire service using data from the Health and Wellness of Women Firefighters Study (n = 3181). Read More

View Article and Full-Text PDF
November 2021

Short inter-pregnancy interval: why is it still high among women in Dar es Salaam?

Pan Afr Med J 2021 6;40:17. Epub 2021 Sep 6.

School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Introduction: in Tanzania, for the past decade, there has been a rising trend of women with short inter-pregnancy interval (IPI) (16% to 19%). Short IPI is associated with poor maternal and neonatal outcomes. We aimed to determine the factors associated with short IPI among women attending antenatal clinic (ANC) at Mnazi Mmoja Hospital, Dar es Salaam, Tanzania. Read More

View Article and Full-Text PDF
November 2021

National cohort and meteorological data based nested case-control study on the association between air pollution exposure and thyroid cancer.

Sci Rep 2021 Nov 3;11(1):21562. Epub 2021 Nov 3.

Hallym Data Science Laboratory, Hallym University College of Medicine, 22, Gwanpyeong-ro 170beon-gil, Dongan-gu, Anyang-si, Gyeonggi-do, 14068, Republic of Korea.

The objective of this study was to evaluate the influence of exposure to meteorological conditions, including air pollution, on thyroid cancer. A nested case-control study was conducted utilizing 4632 patients with thyroid cancer and 18,528 control subjects who were matched at a 1:4 ratio by age group, sex, income, and region of residence. Korean National Health Insurance Service-Health Screening Cohort data from 2002 to 2015 were used. Read More

View Article and Full-Text PDF
November 2021

Investigation of Effects of Gadolinium-Based Contrast Agents on Uterine Contractility Using Isolated Rat Myometrium.

J Magn Reson Imaging 2021 Nov 1. Epub 2021 Nov 1.

Department of Physiology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey.

Background: Despite concerns about safety, gadolinium-based contrast agents (GBCAs) are still used for abdominal and pelvic imaging during pregnancy. Researchers have mainly focused on teratogenicity, while very little is known about their possible direct effects on uterine contractility, yet free gadolinium potentially impacts contractility through interaction with calcium channels.

Purpose: To investigate possible effects of selected GBCAs (namely gadoteridol, gadoversetamide, gadobutrol, gadoterate meglumine, and gadoxetic acid) on the contractility of rat myometrium. Read More

View Article and Full-Text PDF
November 2021

Effect of the Active Cycle of Breathing Technique on Perioperative Outcome in Individuals With Esophagectomy: A Quasi-Experimental Study.

Front Surg 2021 15;8:735947. Epub 2021 Oct 15.

The Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.

The effect of active cycle of breathing technique (ACBT) on EC patients has not been well elucidated. In this research, we aim to explore the effect of ACBT on the perioperative outcomes in patients with esophageal carcinoma who underwent esophagectomy. Patients who underwent esophagectomy in an academic institution from December 2017 to July 2019 were included in this study. Read More

View Article and Full-Text PDF
October 2021

Evaluation of the Antibacterial Activity of Triclosan-incorporated Root Canal Filling Materials for Primary Teeth against .

Int J Clin Pediatr Dent 2021 May-Jun;14(3):393-397

Department of Pedodontics and Preventive Dentistry, Bapuji Dental College and Hospital, Davangere, Karnataka, India.

Aim And Objective: To compare the antibacterial activity of root canal filling materials namely zinc oxide eugenol and Endoflas FS with or without the incorporation of Triclosan.

Materials And Methods: The study consisted of four groups, with 15 samples in each group: group I (zinc oxide eugenol paste), group Ia (zinc oxide eugenol paste + 2.5% Triclosan), group II (Endoflas FS), and group IIa (Endoflas FS + 2. Read More

View Article and Full-Text PDF
November 2021

The association of parity/live birth number with incident type 2 diabetes among women: over 15 years of follow-up in The Tehran Lipid and Glucose Study.

BMC Womens Health 2021 Oct 29;21(1):378. Epub 2021 Oct 29.

Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Childbearing may increase the future risk of developing type 2 diabetes mellitus (T2DM) in mothers. However, the issue is not clear completely and not investigated in the Middle East, a region with a high burden of T2DM. In the current study, we examined the association of parity/live birth number with incident T2DM among Iranian women. Read More

View Article and Full-Text PDF
October 2021

Associations of CB1 cannabinoid receptor (CNR1) gene polymorphisms with risk for alcohol dependence: Evidence from meta-analyses of genetic and genome-wide association studies.

Medicine (Baltimore) 2021 Oct;100(43):e27343

Department of Psychiatry, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.

Objectives: Reported associations of the cannabinoid receptor 1 (CNR1) single nucleotide polymorphisms (SNPs) with alcohol dependence (AD) have been inconsistent, prompting a meta-analysis to obtain more precise estimates.

Methods: A Boolean search of 4 databases (PubMed, Scopus, Google Scholar, and Mednar) sought articles that evaluated the association between CNR1 polymorphisms and risk of AD. We selected the articles with sufficient genotype frequency data to enable calculation of odds ratios (ORs) and 95% confidence intervals (CIs). Read More

View Article and Full-Text PDF
October 2021

High risk of acute kidney injury in Malawian trauma patients: a prospective observational cohort study.

BMC Nephrol 2021 Oct 28;22(1):354. Epub 2021 Oct 28.

Department of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC, USA.

Background: Trauma is a common cause of acute kidney injury (AKI). Yet little data exist regarding trauma-related-AKI in low-resourced settings, where the majority of deaths from AKI and trauma occur. We prospectively evaluated epidemiology of AKI in hospitalized Malawian trauma patients. Read More

View Article and Full-Text PDF
October 2021

HIV Preventive Behaviors and Associated Factors among Gold Mining Workers in Dima District, Southwest Ethiopia, 2019: Community-Based Cross-Sectional Study.

Biomed Res Int 2021 18;2021:4797590. Epub 2021 Oct 18.

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Mizan Tepi University, Mizan-Aman, Ethiopia.

Background: HIV/AIDS is becoming more prevalent over time, resulting in a considerable number of deaths. In 2017, 36.9 million (35. Read More

View Article and Full-Text PDF
October 2021

Late antenatal care initiation and its contributors among pregnant women at selected public health institutions in Southwest Ethiopia.

Pan Afr Med J 2021 24;39:264. Epub 2021 Aug 24.

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Aman, Ethiopia.

Introduction: early commencement of antenatal care by pregnant women as well as regular visits has the potential to affect maternal and fetal outcomes positively. Even with antenatal care, the intervention requires fewer resources; however, most pregnant women in sub-Saharan Africa have begun late for antenatal care services. This study aimed to assess the magnitude and contributors of late antenatal care initiation among pregnant women at selected public health institutions of the Bench-Sheko Zone in southwest Ethiopia. Read More

View Article and Full-Text PDF
November 2021

Circulating Inflammation Markers and Pancreatic Cancer Risk: A Prospective Case-Cohort Study in Japan.

Cancer Epidemiol Biomarkers Prev 2021 Oct 25. Epub 2021 Oct 25.

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Background: Previous prospective studies of associations between circulating inflammation-related molecules and pancreatic cancer risk have included limited numbers of markers.

Methods: We conducted a case-cohort study nested within the Japan Public Health Center-based Prospective Study Cohort II. We selected a random subcohort ( = 774) from a total of 23,335 participants aged 40 to 69 years who returned a questionnaire and provided blood samples at baseline. Read More

View Article and Full-Text PDF
October 2021

Comparison of Postoperative Port-Site Pain After Gallbladder Retrieval From Epigastric Versus Umbilical Port in Patients of Laparoscopic Cholecystectomy for Symptomatic Cholelithiasis: A Randomized Controlled Trial.

Cureus 2021 Sep 18;13(9):e18087. Epub 2021 Sep 18.

Surgery, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, IND.

Introduction Gallbladder (GB) retrieval is an important cause of postoperative pain (POP) after laparoscopic cholecystectomy (LC). Retrieval is through the epigastric or umbilical port based on the surgeon's preference. There is limited evidence to support the superiority of one port over the other in terms of POP. Read More

View Article and Full-Text PDF
September 2021

Identification and Validation of Genomic Regions Associated With Charcoal Rot Resistance in Tropical Maize by Genome-Wide Association and Linkage Mapping.

Front Plant Sci 2021 8;12:726767. Epub 2021 Oct 8.

International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Hyderabad, India.

Charcoal rot is a post-flowering stalk rot (PFSR) disease of maize caused by the fungal pathogen, . It is a serious concern for smallholder maize cultivation, due to significant yield loss and plant lodging at harvest, and this disease is expected to surge with climate change effects like drought and high soil temperature. For identification and validation of genomic variants associated with charcoal rot resistance, a genome-wide association study (GWAS) was conducted on CIMMYT Asia association mapping panel comprising 396 tropical-adapted lines, especially to Asian environments. Read More

View Article and Full-Text PDF
October 2021