27,857 results match your criteria international recommendations

Assessing Data Adequacy for High Blood Pressure Clinical Decision Support: A Quantitative Analysis.

Appl Clin Inform 2021 Aug 4;12(4):710-720. Epub 2021 Aug 4.

iParsimony, Washington, District of Columbia, United States.

Objective:  This study examines guideline-based high blood pressure (HBP) and hypertension recommendations and evaluates the suitability and adequacy of the data and logic required for a Fast Healthcare Interoperable Resources (FHIR)-based, patient-facing clinical decision support (CDS) HBP application. HBP is a major predictor of adverse health events, including stroke, myocardial infarction, and kidney disease. Multiple guidelines recommend interventions to lower blood pressure, but implementation requires patient-centered approaches, including patient-facing CDS tools. Read More

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Examining the sources of evidence in e-cigarette policy recommendations: A citation network analysis of international public health recommendations.

PLoS One 2021 4;16(8):e0255604. Epub 2021 Aug 4.

MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, United Kingdom.

Background: Public health policies and recommendations aim to be informed by the best available evidence. Evidence underpinning e-cigarettes policy recommendations has been necessarily limited due to the novelty of the technology and the lack of long-term epidemiological studies and trials. Some public health bodies have actively encouraged e-cigarette use whilst others have raised concerns over introducing new health risks and renormalising tobacco smoking. Read More

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Enhancing Recruitment and Retention of Minority Populations for Clinical Research in Pulmonary, Critical Care, and Sleep Medicine: An Official American Thoracic Society Research Statement.

Am J Respir Crit Care Med 2021 Aug;204(3):e26-e50

Well-designed clinical research needs to obtain information that is applicable to the general population. However, most current studies fail to include substantial cohorts of racial/ethnic minority populations. Such underrepresentation may lead to delayed diagnosis or misdiagnosis of disease, wide application of approved interventions without appropriate knowledge of their usefulness in certain populations, and development of recommendations that are not broadly applicable. Read More

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A Predictive model to quantify joint torques and support reaction forces when using a smartphone while standing with support.

Ergonomics 2021 Aug 4:1-24. Epub 2021 Aug 4.

Euro-Mediterranean Institute of Research and Innovation in Ergonomics and Biomechanics for the Connected Human - ErBio-Connect - CS 10121, 83418 HYERES CEDEX, France.

The present study had a dual objective: 1) to present and validate a predictive model of standing posture in the sagittal plane, joint torques and support forces for a smartphone user built from biomechanical principles; 2) propose risk scales for joint torques and reaction forces based on simulations in order to use them into the musculoskeletal disorders prevention. Comparison of the modeled data with experimental measurements (400 tested postures with sample size verification) for calling and texting tasks highlights the model's ability to correctly estimate posture and reaction forces on the ground. The model was able to provide estimates of the range of variation of each parameter for a wide range of environmental conditions as a function of the user body mass index (setting between 12. Read More

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Child alcohol use disorder in Eastern Uganda: screening, diagnostics, risk factors and management of children drinking alcohol in Uganda (TREAT C-AUD): a mixed-methods research protocol.

BMJ Paediatr Open 2021 28;5(1):e001214. Epub 2021 Jul 28.

School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.

Background: Following a finding of alcohol use among children aged 5-8 years old in Mbale, Uganda, this project investigates the magnitude of alcohol and substance use among children ged 6-13 years old and related household, community, school, health system and clinical factors.

Methods: The project includes four larger work packages (WPs). WP1 comprises management, WP2 and 3 include the scientific components and WP4 includes integration of results, dissemination, policy and implementation advice. Read More

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Peter Rabbit is a Badger in Disguise: Deconstructing the Belief System of the Institute for Clinical and Economic Review in Health Technology Assessment.

Paul C Langley

Innov Pharm 2021 25;12(2). Epub 2021 May 25.

College of Pharmacy, University of Minnesota - Twin Cities MN; Maimon Research, Tucson AZ.

The Institute for Clinical and Economic Review (ICER), a Boston-based consulting group, has seen itself as the lead organization in the US for evaluating pharmaceuticals and, at product launch, making recommendations for pricing and access. Previous commentaries in Innovations in Pharmacy have made the case that the ICER analytical framework is nonsensical. It abandons the standards of normal science in favor of inventing evidence through unsupported assertions regarding measurement properties and lifetime assumption driven simulations. Read More

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Indications for computed tomography use and frequency of traumatic abnormalities based on real-world data of 2405 pediatric patients with minor head trauma.

Surg Neurol Int 2021 28;12:321. Epub 2021 Jun 28.

Department of Neurosurgery, Baba Memorial Hospital, Sakai City, Osaka, Japan.

Background: In pediatric patients with minor head trauma, computed tomography (CT) is often performed beyond the scope of recommendations that are based on existing algorithms. Herein, we evaluated pediatric patients with minor head trauma who underwent CT examinations, quantified its frequency, and determined how often traumatic findings were observed in the intracranial region or skull.

Methods: We retrospectively reviewed the medical records and neuroimages of pediatric patients (0-5 years) who presented at our hospital with minor head trauma within 24 h after injury. Read More

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Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review.

Clin Kidney J 2021 Aug 3;14(8):1871-1878. Epub 2021 Mar 3.

University of Rennes, CHU Rennes, INSERM, EHESP, IRSET (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000, Rennes, France.

Although pregnancy remains exceptional in women after heart, liver or lung transplant, obstetricians and nephrologists are regularly confronted with pregnancy in renal transplant recipients. National and international registries have described the epidemiology of maternal, foetal and neonatal complications, and transplantation societies have published recommendations on the monitoring of these high-risk pregnancies. In this review, we summarize the existing data on maternal and foetal complications of pregnancies in women after renal transplant, especially the management of immunosuppression. Read More

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Assessing the biogeographical and socio-ecological representativeness of the ILTER site network.

Ecol Indic 2021 Aug;127:107785

Environment Agency Austria, Department for Ecosystem Research and Monitoring, Spittelauer Lände 5, A-1090 Vienna, Austria.

The challenges posed by climate and land use change are increasingly complex, with rising and accelerating impacts on the global environmental system. Novel environmental and ecosystem research needs to properly interpret system changes and derive management recommendations across scales. This largely depends on advances in the establishment of an internationally harmonised, long-term operating and representative infrastructure for environmental observation. Read More

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Development of targeted, theory-informed interventions to improve bronchiolitis management.

BMC Health Serv Res 2021 Aug 3;21(1):769. Epub 2021 Aug 3.

Children's Emergency Department, Starship Children's Hospital, Private Bag 92024, Auckland, 1142, New Zealand.

Background: Despite international guidelines providing evidence-based recommendations on appropriate management of infants with bronchiolitis, wide variation in practice occurs. This results in infants receiving care of no benefit, with associated cost and is potentially harmful. Theoretical frameworks are increasingly used to develop interventions, utilising behaviour change techniques specifically chosen to target factors contributing to practice variation, with de-implementation often viewed as harder than implementing. Read More

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[Long-lasting souvenir from Cameroon - Persistent, massive hypereosinophilia in amicrofilaremic infection with Loa loa].

Dtsch Med Wochenschr 2021 Aug 3;146(15):1005-1008. Epub 2021 Aug 3.

Universitätsklinikum Bonn, Klinik und Poliklinik für Dermatologie und Allergologie.

Introduction:  Diagnosis of a polysymptomatic, rare parasitosis requires collaboration of internal specialists, tropical disease specialists, parasitologists and dermatologists.

History:  The course of disease is shown in a 66-year-old woman who regularly travels to Cameroon and presented with remarkable hypereosinophilia and pruritus with urticarial swellings.

Findings And Diagnosis:  Using interdisciplinary diagnostics based on travel history, symptoms and laboratory results an occult amicrofilaraemic infection with immunological hyperreaction to the parasite antigen, reactive hypereosinophilia and high antibody titers was diagnosed. Read More

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Management Approach to Acute Myeloid Leukemia Leveraging the Available Resources in View of the Latest Evidence: Consensus of the Saudi Society of Blood and Marrow Transplantation.

JCO Glob Oncol 2021 Jul;7:1220-1232

Department of Oncology, Ministry of the National Guard-Health Affairs, Riyadh, Saudi Arabia.

Purpose: Acute myeloid leukemia (AML) is the most prevalent acute leukemia in adults and is responsible for the majority of cancer-related mortality. In Saudi Arabia, leukemia is ranked the fifth most prevalent type of malignancy in adults. Our aim is to review existing epidemiologic data in Saudi Arabia and develop consensus guidelines for management of AML. Read More

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The Italian Society for Rheumatology clinical practice guidelines for the diagnosis and management of fibromyalgia Best practices based on current scientific evidence.

Reumatismo 2021 Aug 3;73(2):89-105. Epub 2021 Aug 3.

Epidemiology Unit, Italian Society for Rheumatology, Milan, Italy; Unità di Reumatologia, Azienda Ospedaliera Città della Salute e della Scienza di Torino.

Fibromyalgia or fibromyalgia syndrome (FMS) is defined as a central sensitization syndrome characterized by the dysfunction of neurocircuits detecting, transmitting and processing nociceptive stimuli; the prevalent manifestation is musculoskeletal pain. In addition to pain, there are multiple accompanying symptoms, in common with other algo-dysfunctional syndromes, which are reflected in a broad spectrum of somatic, neurocognitive and neuro-vegetative manifestations. An evidence-based approach is essential in FMS management, in order to improve patient health and to reduce its social burden. Read More

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The Italian Society for Rheumatology recommendations for the management of axial spondyloarthritis.

Reumatismo 2021 Aug 3;73(2):71-88. Epub 2021 Aug 3.

Epidemiology Research Unit, Italian Society for Rheumatology, Milan, Italy; ASST Grande Ospedale Metropolitano Niguarda, Milan.

Over the last few years, the landscape of treatments for axial spondyloarthritis (SpA) has been rapidly evolving, urging international scientific societies to draft or update existing clinical practice guidelines (CPGs) on the management of axial SpA. The Italian Society for Rheumatology (SIR) committed to provide revised and adapted evidence- and expert-based recommendations for the management of patients with axial SpA in Italy. A systematic approach to the adaptation of existing CPGs - the ADAPTE methodology - was adopted to obtain updated recommendations suitable for the Italian context. Read More

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Cost-effectiveness analysis of superabsorbent wound dressings in patients with moderate-to-highly exuding leg ulcers in Germany.

Int Wound J 2021 Aug 2. Epub 2021 Aug 2.

Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT, Hall, Tirol, Austria.

The study aims to estimate the cost-effectiveness of superabsorbent wound dressings compared to the standard-of-care (SoC) dressings mix for treatment of patients with moderate-to-highly exuding leg ulcers in the German healthcare settings. A model-based cost-effectiveness analysis was conducted from the German statutory health insurance perspective, following German specific and international recommendations of good research practice. An individual-level (microsimulation) state-transition model has been used with a cycle length of 1 week and time horizon of 6 months. Read More

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Revised guidelines of the French Headache Society for the diagnosis and management of migraine in adults. Part 1: Diagnosis and assessment.

Rev Neurol (Paris) 2021 Jul 30. Epub 2021 Jul 30.

Department of Neurology, Gui de Chauliac Hospital, CHU Montpellier, University of Montpellier, 34000 Montpellier, France.

The French Headache Society proposes updated French guidelines for the management of migraine. The first part of these recommendations is focused on the diagnosis and assessment of migraine. First, migraine needs to be precisely diagnosed according to the currently validated criteria of the International Classification of Headache Disorders, 3d version (ICHD-3). Read More

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Cognitive Impairment in Grandparents: A Systematic Review.

Psychiatry Investig 2021 Jul 22;18(7):593-602. Epub 2021 Jul 22.

Department of Clinical Neurosciences and Mental Health, Faculty of Medicine of Porto University, Porto, Portugal.

Objective: To evaluate the relationship between grandparenting and the cognitive impairment in older persons.

Methods: The protocol was submitted to the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42018105849. Authors conducted a systematic review, following "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA) recommendations. Read More

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Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors: evidence-based recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Lancet Diabetes Endocrinol 2021 Jul 30. Epub 2021 Jul 30.

Department for Pediatric Hematology and Oncology CHU Nord, University Hospital Saint-Etienne, Saint-Priest en Jarez, France; 28U1059 Sainbiose, University Jean Monnet, Saint-Etienne, France.

Childhood, adolescent, and young adult cancer survivors are at increased risk of reduced bone mineral density. Clinical practice surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could improve bone mineral density parameters and prevent fragility fractures. Discordances across current late effects guidelines necessitated international harmonisation of recommendations for bone mineral density surveillance. Read More

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Lessons Learned From a Large Cross-Border Field Simulation Exercise to Strengthen Emergency Preparedness in East Africa, 2019.

Health Secur 2021 Jul 30. Epub 2021 Jul 30.

Prime Minister's Office, United Republic of Tanzania, Disaster Management Department, Dodoma.

Field simulation exercises (FSXs) require substantial time, resources, and organizational experience to plan and implement and are less commonly undertaken than drills or tabletop exercises. Despite this, FSXs provide an opportunity to test the full scope of operational capacities, including coordination across sectors. From June 11 to 14, 2019, the East African Community Secretariat conducted a cross-border FSX at the Namanga One Stop Border Post between the Republic of Kenya and the United Republic of Tanzania. Read More

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A systematic review and meta-analysis of the effectiveness of individual-level interventions to reduce occupational stress perceptions among teachers.

Arch Environ Occup Health 2021 Aug 2:1-15. Epub 2021 Aug 2.

Department of Community Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

Teachers are largely affected by OS, during their most productive years, leading to catastrophic physical, psychological, and economic burden on themselves, families and society by large. Teachers are responsible for producing the workforce of any nation, and thus have a major impact indirectly on the economy and health of a nation. There are several individual-level interventions conducted to reduce occupational stress (OS) among teachers. Read More

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The Holistic Theory of Unpleasant Symptoms.

J Holist Nurs 2021 Aug 2:8980101211031706. Epub 2021 Aug 2.

Integrative Nurse Coach Academy, International Nurse Coach Association, Miami Beach, FL, USA.

This article describes a holistic revisioning of symptom theory for nursing practice. The Holistic Theory of Unpleasant Symptoms (HTOUS), informed by the Science of Unitary Human Beings, describes the complexity of symptom experience and how nursing actions can be associated with its transformation. Existing theories of unpleasant symptoms which broadly describe the antecedents, characteristics, and consequences of symptoms, have been reconceptualized from holistic and integral perspectives. Read More

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Long-term care system for older adults in China: policy landscape, challenges, and future prospects.

Lancet 2020 Oct;396(10259):1362-1372

Department of Global Health and Population, Harvard University, Boston, MA, USA. Electronic address:

In China, the population is rapidly ageing and the capacity of the system that cares for older people is increasingly a concern. In this Review, we provide a profile of the long-term care system and policy landscape in China. The long-term care system is characterised by rapid growth of the residential care sector, slow development of home and community-based services, and increasing involvement of the private sector. Read More

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October 2020

Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative.

JOR Spine 2021 Jun 19;4(2):e1167. Epub 2021 Jul 19.

Department of Orthopaedic Surgery University of California at San Francisco San Francisco California USA.

Background: Histopathological analysis of intervertebral disc (IVD) tissues is a critical domain of back pain research. Identification, description, and classification of attributes that distinguish abnormal tissues form a basis for probing disease mechanisms and conceiving novel therapies. Unfortunately, lack of standardized methods and nomenclature can limit comparisons of results across studies and prevent organizing information into a clear representation of the hierarchical, spatial, and temporal patterns of IVD degeneration. Read More

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Androgen deprivation monotherapy usage in non-metastatic prostate cancer: results from eight European countries.

Cent European J Urol 2021 26;74(2):161-168. Epub 2021 Mar 26.

Ipsen Greece, Medical Department, Athens, Greece.

Introduction: The aim of this study was to investigate the attitudes towards use of androgen deprivation therapy (ADT) as monotherapy for localized or locally advanced prostate cancer (PC).

Material And Methods: A survey using a 28-item, structured, quantitative questionnaire about the management of patients with PC was conducted in eight European countries between February and May 2018. Survey recipients were selected from a private database of healthcare providers. Read More

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The Lived Experiences of Chinese International College Students and Scholars during the Initial COVID-19 Quarantine Period in the United States.

Int J Adv Couns 2021 Jul 28:1-19. Epub 2021 Jul 28.

Virginia Commonwealth University, 1015 W. Main St., P.O. Box 842020, Richmond, VA USA.

The purpose of this study was to explore Chinese international college students' lived experiences during the initial COVID-19 quarantine period in the United States. Using a descriptive phenomenological psychological method, data were gathered from 14 international students and visiting scholars from China using individual and focus group interviews. Four transformed meaning units that formed the structural base of the phenomenal experience were identified as Safety Concerns, The Salience of the English Language, Intersectionality of Policies and Complex Decision Making, and Unexpected Support and Benefits. Read More

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Tofacitinib use in adults with chronic inflammatory disease during the SARS-CoV-2 pandemic: What is known so far?

Curr Ther Res Clin Exp 2021 Jul 25:100639. Epub 2021 Jul 25.

Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Background: Concerns have been raised that the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, or more severe or critical coronavirus disease (COVID-19), may be higher in immunocompromised individuals receiving immunomodulatory therapies, compared with immunocompetent individuals. Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ulcerative colitis (UC), and polyarticular course juvenile idiopathic arthritis. To date, data on tofacitinib treatment during the COVID-19 pandemic are limited. Read More

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Habitual Physical Activity in Patients with Myasthenia Gravis Assessed by Accelerometry and Questionnaire.

J Neuromuscul Dis 2021 Jul 28. Epub 2021 Jul 28.

Copenhagen Neuromuscular Center, Department of Neurology, Copenhagen University Hospital -Rigshospitalet, Copenhagen, Denmark.

Background: Physical activity (PA) in patients with myasthenia gravis (MG) is considered safe and beneficial, and an active lifestyle is required to obtain the health benefits of exercise. However, as the disease leads to physical impairments an insight into the overall PA habits in this patient population is relevant but lacking.

Objective: To measure habitual physical activity in a Danish cohort of patients with MG measured by accelerometer and questionnaire, and to determine relevant predictors for PA intensities. Read More

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Stakeholder views on taxation of sugar-sweetened beverages and its adoption in the Netherlands.

Health Promot Int 2021 Aug 1. Epub 2021 Aug 1.

Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, and Amsterdam Public Health Research Institute, De Boelelaan 1105, 1081 HV Amsterdam, the Netherlands.

An increasing number of governments worldwide have introduced a tax on sugar-sweetened beverages (SSB) for public health. However, the adoption of such a policy is still debated in many other countries, such as in the Netherlands. We investigated Dutch stakeholder views on taxation of SSB and perceived barriers and facilitators to its adoption in the Netherlands. Read More

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European PanCareFollowUp Recommendations for surveillance of late effects of childhood, adolescent, and young adult cancer.

Eur J Cancer 2021 Jul 28;154:316-328. Epub 2021 Jul 28.

Princess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, Utrecht, 3584 CS, the Netherlands.

Background: Long-term follow-up (LTFU) care for childhood, adolescent, and young adult (CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence-based guidelines are needed to inform optimal surveillance strategies, but many topics are yet to be addressed by the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG). Therefore, the PanCareFollowUp Recommendations Working Group collaborated with stakeholders to develop European harmonised recommendations in anticipation of evidence-based IGHG guidelines. Read More

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Sedoanalgesia in neonatal units.

An Pediatr (Engl Ed) 2021 Jul 28. Epub 2021 Jul 28.

Servicio de Neonatología, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Electronic address:

Pain recognition and management continues to be a challenge for health professionals in Neonatal Intensive Care Units. Many of the patients are routinely exposed to repeated painful experiences with demonstrated short- and long-term consequences. Preterm babies are a vulnerable high-risk population. Read More

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