240 results match your criteria intermittent testicular


Testicular vein thrombosis mimicking epididymo-orchitis after suspected Covid-19 infection.

SAGE Open Med Case Rep 2021 4;9:2050313X211022425. Epub 2021 Jun 4.

The Whiteley Clinic, Guildford, UK.

A 70-year-old man presented to our vein clinic with intermittent and recurrent left testicular and groin pain, clinically resembling epididymo-orchitis. He had never had any genitourinary problems until contracting a severe flu-like illness in January 2020, strongly suspected to have been Covid-19. He had failed to respond on four separate occasions to antibiotics prescribed by his GP and had only responded on these occasions to aspirin. Read More

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Granulomatous orchitis: case report and review of the literature.

J Int Med Res 2021 May;49(5):3000605211003773

Department of Urology, People's Hospital of Hebei Province, Shijiazhuang, Hebei Province, China.

We report the disease characteristics, diagnosis, and treatment of granulomatous orchitis. A 38-year-old man presented with a history of intermittent swelling, pain, and discomfort in the right testicle of 3 days' duration. Unenhanced magnetic resonance imaging (MRI) of the testis and scrotum revealed an oval mass in the right testis measuring approximately 17 mm in diameter, with clear borders and a target ring-like appearance from periphery to center. Read More

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Does mirabegron deteriorate spermatogenesis? A lesson from spinal cord injury cases.

Low Urin Tract Symptoms 2021 Apr 30. Epub 2021 Apr 30.

International Center for Reproductive Medicine, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.

Objectives: To evaluate whether the long-term usage of mirabegron, which was reported to have potential side effects on male reproductive organs in animal studies, was harmful to spermatogenesis in human testis.

Methods: Thirty consecutive patients with spinal cord injury (20-48 years old) who performed clean intermittent catheterization were involved in this study. Ten patients were treated with mirabegron (50 mg/d) for more than 2 years and refrained from using an antimuscarinic agent due to the side effects of constipation and dry mouth. Read More

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Rat Tumour Histopathology Associated with Experimental Chronic Dietary Exposure to Ochratoxin A in Prediction of the Mycotoxin's Risk for Human Cancers.

Toxins (Basel) 2021 03 12;13(3). Epub 2021 Mar 12.

Centre for Environmental Policy, Imperial College London, London SW7 2AZ, UK.

Mammalian animal toxicity of ochratoxin A (OTA) has focused largely in the past half-century on pigs because of initial recognition of it as a principal cause of intermittent growth suppression and renal disease caused by mouldy feed. Subsequent classical toxicology has used laboratory rodents because renal pathology in pigs raised questions concerning possible involvement in the human idiopathic bilateral renal atrophy of Balkan endemic nephropathy for which OTA was a focus of attention for human nephropathy through 1980s and into 2000s. Emphasis on human nephropathy has more recently concerned the plant metabolite aristolochic acid. Read More

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Repeated Doses of Ketamine Affect the Infant Rat Urogenital System.

Drug Des Devel Ther 2021 11;15:1157-1165. Epub 2021 Mar 11.

Medical Faculty, Department of Biochemistry, Gazi University, Ankara, Turkey.

Aim: Long-term ketamine use is known to create an interstitial cystitis-like problem in the bladder. It is known that long-term intermittent ketamine is applied to the children receiving radiotherapy for sedation. This study was planned to investigate whether this effect seen in the bladder causes similar changes in the kidneys, testicles, epididymis and ductus deferens. Read More

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A Case of Posterior Nutcracker Syndrome Revealed in the Aerospace Environment.

Aerosp Med Hum Perform 2021 Jan;92(1):54-56

Nutcracker syndrome is caused by a rare anatomic variant where the left renal vein is trapped between the aorta and the superior mesenteric artery. Posterior nutcracker syndrome is an even rarer entity, characterized by the retro-aortic positioning of the renal vein, causing compression between the aorta and spinal vertebrae. Symptoms include microscopic or frank hematuria, flank pain, varicocele, pelvic congestion syndrome, and abdominal pain. Read More

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January 2021

Long-term protective effects of the combination of intermittent reperfusion and hypothermia on reperfusion injury in an experimental testicular torsion model.

J Pediatr Surg 2020 Nov 26. Epub 2020 Nov 26.

Adnan Menderes University Medical Faculty,Department of Pediatric Surgery, Aydin, Turkey.

Introduction: There are many significantfactors in testicular injury which determine the prognosis in testicular torsion. Reperfusion injury following detorsion also has a significant effect on testicular injury.This study was planned considering that with the implementation of intermittent reperfusion and hypothermia, reperfusion injury can be reduced, and such an application might have a positive effect on testicular tissue in the long term. Read More

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November 2020

Preoperative Predictors of Failure of Microsurgical Spermatic Cord Denervation for Men With Chronic Orchialgia.

Urology 2021 Mar 27;149:30-33. Epub 2020 Nov 27.

Austin Fertiity & Reproductive Medicine/Westlake IVF.

Objective: To evaluate predictors of failure of microsurgical spermatic cord denervation (MSCD) for men with chronic orchialgia.

Methods: Retrospective chart review of men who underwent MSCD. Outcomes were recorded with potential preoperative predictors of failure. Read More

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Acute testicular torsion: A critical analysis of presentation, management and outcome in southeast Nigeria.

Niger J Clin Pract 2020 Nov;23(11):1536-1541

Department of Surgery, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Ebonyi State, Nigeria.

Objectives: The aim of this study is to evaluate the pattern of presentation, anatomic anomalies, and treatment outcomes in patients presenting with acute testicular torsion in a tertiary health institution in southeast Nigeria.

Methods: This was a prospective study of all consecutive patients with acute testicular torsion seen from January 2011 to November 2019 at our institution. Their demographic and clinical data were analyzed. Read More

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November 2020

Biological Network Model of Effect of Chronic Intermittent Hypoxia on Spermatogenesis in Rats.

Med Sci Monit 2020 Sep 6;26:e925579. Epub 2020 Sep 6.

Andrology Department, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (mainland).

BACKGROUND The aim of this study was to explore the effect of obstructive sleep apnea hypopnea syndrome (OSAHS) on spermatogenesis and the effects of the expression of related proteins. MATERIAL AND METHODS Rats in Group A were normoxic (exposed to a normal level of oxygen). Rats in Group B were exposed to intermittent hypoxia. Read More

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September 2020

Germ cells positive for PLAP and c-Kit in 11-16 year old normal boys with ongoing spermatogenesis.

Pediatr Surg Int 2020 Oct 9;36(10):1249-1254. Epub 2020 Aug 9.

The Department of Pediatric Surgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Introduction: Positive staining of testicular germ cells for PLAP and c-Kit beyond infancy may be associated with the presence of GCNIS (Germ Cell Neoplasia In Situ). We recently reported our findings of positive staining of normal, infantile germ cells for PLAP, and c-Kit up to 2 years of age, contrary to previous studies. The present study aims to elucidate whether otherwise normal testes of boys undergoing puberty express PLAP, c-Kit, Oct3/4, or D2-40. Read More

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October 2020

The bell-clapper deformity of the testis: The definitive pathological anatomy.

J Pediatr Surg 2020 Jun 25. Epub 2020 Jun 25.

Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. Electronic address:

Introduction: The bell-clapper deformity (BCD) predisposes to intravaginal torsion (IVT) and is classically bilateral. The precise pathological definition of what constitutes a BCD is not clear. The current study aims to clarify the specific anatomic details of this anomaly. Read More

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Case of intermittent testicular torsion and de-torsion captured on scrotal ultrasound.

ANZ J Surg 2021 03 6;91(3):E135-E136. Epub 2020 Aug 6.

Nepean Urology Research Group, Nepean Hospital, Sydney, New South Wales, Australia.

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Mesenteric metastases from mature teratoma of the testis: A case report.

Asian J Urol 2020 Jul 5;7(3):322-325. Epub 2018 Jun 5.

Department of Surgery, University of Melbourne, Austin Health, Melbourne, Australia.

Metastatic spread of testicular cancer has been well documented, with 95% of cases involving para-aortic retroperitoneal lymph nodes. Mesenteric lymphatic basins do not lie within the canonical drainage pathway of the testes and represent a rare site of metastasis. Various mechanisms of spread to the mesentery have been described, including direct extension and haematogenous dissemination. Read More

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Young Man With Intermittent Flank Pain.

Ann Emerg Med 2020 06;75(6):e31-e32

Department of Emergency, School of Medicine, College of Medicine, Taipei, Taiwan; Emergency Department, Department of Emergency and Critical Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

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Urologic Conditions in Infants and Children: Inguinal Hernia, Hydrocele, and Cryptorchidism.

FP Essent 2020 Jan;488:16-20

LewisGale Medical Center Family Medicine Residency Program, 1900 Electric Rd Salem, VA 24153.

In children, inguinal hernias, hydroceles, and cryptorchidism typically are associated with a patent processus vaginalis. Inguinal hernias occur in 3.5%-5% of full-term newborns and 9%-11% of premature newborns. Read More

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January 2020

Rapid testicular metastasis from bladder transitional urothelial carcinoma after radical cystoprostatectomy: A case report.

Medicine (Baltimore) 2019 Nov;98(48):e18000

Department of Urology.

Rationale: Bladder cancer (BC) is commonly diagnosed in the urinary system and the most common subtype is transitional urothelial carcinoma (TCC). Even with the best treatment, tumor recurrence and metastases always occur. While clinicians commonly observe the metastases to pelvic lymph nodes, liver, lung, and bone, it may infrequently spread to some uncommon locations. Read More

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November 2019

A comparison of clinical outcomes of acute testicular torsion between prepubertal and postpubertal males.

J Pediatr Urol 2019 Dec 6;15(6):610-616. Epub 2019 Aug 6.

Division of Pediatric Urology, Children's Hospital of Wisconsin, Children's Hospital of Wisconsin, 999 N, 92nd Street, Suite 330, Milwaukee, WI, 53226, USA. Electronic address:

Short Introduction/background: Surgical intervention for acute testicular torsion can require either orchiopexy or orchiectomy. The decision of which surgery to perform is dependant on the amount of time that the testicle experienced ischemia and the viability of the testicle after reperfusion.

Objective: It is hypothesized that (1) there is a difference in orchiectomy and orchiopexy rates between prepubertal and postpubertal males with acute testicular torsion and (2) presenting symptoms may vary between the two age groups as prepubertal males may present with atypical symptoms, which could result in delayed presentation and diagnosis. Read More

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December 2019

Comparison of the effects of intermittent reperfusion and hypothermia in preventing testicular ischemia-reperfusion injury in the testicular torsion model in rats.

J Pediatr Urol 2019 Dec 20;15(6):617-623. Epub 2019 Sep 20.

Adnan Menderes University Medical School, Department of Pediatric Surgery, Turkey.

Introduction: Reperfusion injury after detorsion in testicular torsion is a clinical problem. This study was planned to investigate the protective effect of intermittent reperfusion in hypothermia-applied testicles.

Materials And Methods: A total of 40 adult male rats were used, and 5 groups were created: sham (Sh; n = 8), torsion (T; torsion-detorsion) (n = 8), intermittent reperfusion (IR; n = 8), hypothermia (H; n = 8), and intermittent reperfusion+hypothermia (H+IR; n = 8). Read More

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December 2019

Is inguinal hernia a risk factor for varicocele in the young male population?

Arch Esp Urol 2019 Sep;72(7):697-704

Department of Anatomy. Lokman Hekim University. Çankaya. Ankara. Turkey.

Objectives: The aim of this study is to investigate the role of the inguinal hernia over the development of varicocele, in cases with accompanying inguinal hernia.

Methods: The continuous variables were calculated from mean and standard deviation, and intermittent variables were calculated over percentage and frequency. Normality testing was performed on continuous variables using the Kolmogorov-Smirnov test. Read More

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September 2019

Chronic intermittent hypoxia stimulates testosterone production in rat Leydig cells.

Life Sci 2019 Sep 25;233:116694. Epub 2019 Jul 25.

Department of Physiology, School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan; Medical Center of Aging Research, China Medical University Hospital, Taichung 40402, Taiwan; Department of Biotechnology, College of Health Science, Asia University, Taichung 41354, Taiwan; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan. Electronic address:

Aims: The hypoxia-stimulated response of the endocrine system depends on the kind and duration of hypoxia. Hypoxia has been reported to stimulate testosterone (T) production in rats, but the mechanisms remain to be investigated.

Materials And Methods: Male rats were divided into two groups. Read More

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September 2019

A case report on mother-to-child transmission of Brucella in human, China.

BMC Infect Dis 2019 Jul 27;19(1):666. Epub 2019 Jul 27.

State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Background: Human brucellosis is endemic in China and commonly occurs through contact with infected animals from working with livestock or consumption of unpasteurized dairy products. Although rare, human-to-human, and possible sexual transmission, of Brucella has been reported. In this report, we describe a case of likely mother-to-child transmission of Brucella in Hunan Province, China. Read More

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Relationship between chronic testicular pain and mental health diagnoses.

Transl Androl Urol 2019 Mar;8(Suppl 1):S38-S44

Urology Clinic, Brooke Army Medical Center, San Antonio, TX, USA.

Background: Chronic testicular pain (orchialgia) has been defined as intermittent or constant unilateral or bilateral testicular pain that lasts 3 months or longer, significantly interfering with daily activities, and prompting the patient to seek medical attention. In many instances, the etiology of the pain is not identified. The contribution of psychological factors is unclear. Read More

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Korean Red Ginseng ( Meyer) with enriched Rg3 ameliorates chronic intermittent heat stress-induced testicular damage in rats multifunctional approach.

J Ginseng Res 2019 Jan 22;43(1):135-142. Epub 2018 Jun 22.

Department of Biomedical Chemistry, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea.

Background: Meyer, known as Korean Red Ginseng (KRG), is one of the important age-old traditional herbs used in boosting and improving male fertility. In this study, the effects of Rg3-enriched KRG extract (KGC04P) on heat stress-induced testicular damage in experimental rats was evaluated.

Methods: Male rats (Sprague-Dawley) were divided into four groups (n = 10): normal control (NC), heat-stressed control (HC), heat-stressed plus KGC04P-100 mg/kg (HK100), and heat-stressed plus KGC04P-200 mg/kg (HK200) groups. Read More

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January 2019

[Pathologies of peritoneo-vaginal canal in pediatric surgery at the teaching hospital Gabriel Touré].

Mali Med 2018 ;33(2):17-20

Service de chirurgie générale, C.H.U Gabriel TOURE, Bamako, Mali.

The closure anomalies of the peritoneal-vaginal canal include several clinical entities, which are at the origin of various symptomatology.

Objective: To study the anatomo-clinical and therapeutic aspects of pathologies of the peritoneal-vaginal canal.

Materials And Method: This was a prospective study from January 1 to December 31, 2015 carried out in the pediatric surgery department of University Hospital Gabriel Touré. Read More

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Cocaine alters the mouse testicular epigenome with direct impact on histone acetylation and DNA methylation marks.

Reprod Biomed Online 2018 09 17;37(3):269-278. Epub 2018 Aug 17.

Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina. Electronic address:

Research Question: Recent evidence suggests that cocaine administration in animal models can trigger non-genetic inheritance of addiction traits from father to offspring, affecting development and behaviour. Is chronic cocaine intake involved in alterations of epigenetic homeostasis in the testis?

Design: Epigenetic marks and mediators in testis and isolated germ cells of adult mice treated with cocaine (10 mg/kg) or vehicle (sterile saline solution) were evaluated in an intermittent binge protocol: three intraperitoneal injections, 1 h apart, one day on/off for 13 days, collecting tissue 24 h after the last binge administration (day 14).

Results: It was shown that chronic cocaine intake in mice disrupts testicular epigenetic homeostasis, increasing global methylated cytosine levels in DNA from germ cells and sperm. Read More

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September 2018

Flaxseed Can Reduce Hypoxia-Induced Damages in Rat Testes.

Int J Fertil Steril 2018 Jun 20;12(3):235-241. Epub 2018 Jun 20.

Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic Address:

Bachground: Hypoxia causes detrimental effects on the structure and function of tissues through increased production of reactive oxygen species that are generated during the re-oxygenation phase of intermittent and continuous hypobaric hypoxia. This study was carried out to evaluate the effects of flaxseed (Fx) in reducing the incidence of hypoxia in rat testes.

Materials And Methods: In this experimental study, 24 adult Wistar rats were randomly divided into four groups: i. Read More

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Intermittent resistance exercise and obesity, considered separately or combined, impair spermatic parameters in adult male Wistar rats.

Int J Exp Pathol 2018 04 21;99(2):95-102. Epub 2018 May 21.

General Biology Department, Biological Sciences Center, State University of Londrina-UEL, Londrina, Brazil.

Obesity and absence of physical exercise are global problems that affect concentration and sperm quality in the male reproductive system. The purpose of this study was to examine the effect of obesity and resistance training, considered separately or in association, on testicular function and reproductive capacity. Twenty pubertal male Wistar rats were distributed into four groups: control (C) and exercise (E) groups that received standard rat chow; and obese (O) and obese with exercise (OE) groups that received a high-fat diet. Read More

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Impaired serum inhibin-B and number of germ cells in boys with cryptorchidism following heavily gestational maternal smoking.

J Pediatr Surg 2019 Apr 5;54(4):809-814. Epub 2018 Apr 5.

The Department of Pediatric Surgery, Copenhagen University Hospital Rigshospitalet, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

Purpose: A meta-analysis including 11,900 cases showed that maternal gestational smoking was associated with increased risk of cryptorchidism. The aim of study was to investigate whether a hormone profile of cryptorchid boys and a supplementing histopathological evaluation of testicular biopsies could add detailed knowledge to the impact of maternal gestational smoking on pathogenesis of cryptorchidism.

Methods: 601 cryptorchid boys aged 4 months to 14 years old were included. Read More

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A 26-Year-Old Male with a 14-Year History of Left Intermittent Testicular Torsion Treated with Self-Manual Reduction.

Curr Urol 2018 Mar 20;11(3):166-168. Epub 2018 Feb 20.

Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

Intermittent testicular torsion presents with recurrent episodes of severe unilateral testicular pain with resolution of symptoms between episodes. We present a case of a 26-year-old man with a 14-year history of intermittent testicular pain presenting to the urology clinic for elective surgical evaluation. He reported monthly symptoms for many years and had learned to manually reduce the torsion with each episode. Read More

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