Curr Opin Cell Biol 2021 Apr 13;71:120-129. Epub 2021 Apr 13.
Institute of Structural and Molecular Biology, University College London, Gower Street, London, WC1E 6BT, UK; Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London, WC1E 7HX, UK. Electronic address:
Endocytosis mediates the uptake of extracellular proteins, micronutrients and transmembrane cell surface proteins. Importantly, many viruses, toxins and bacteria hijack endocytosis to infect cells. The canonical pathway is clathrin-mediated endocytosis (CME) and is active in all eukaryotic cells to support critical house-keeping functions. Read More