Prog Biophys Mol Biol 2021 Sep 9. Epub 2021 Sep 9.
Bruker Corporation, 40 Manning Road, Billerica, MA, 01821, USA; Visiting Scholar, Harvard University, Origins of Life Initiative, Department of Chemistry & Chemical Biology, 12 Oxford Street, Cambridge, MA, 02138, USA; Member, The Oncology Think Tank (TOTT), Columbia University, New York, NY, USA. Electronic address:
The evolution of early life and of contemporary viruses has been driven in significant part by random genetic mutations, while modern unicellular and organismal evolution primarily leverages evolved, efficient and active cell biology processes for adaptive changes prior to selection. Random mutations are often buffered by cell homeostasis, or they have a negative role, e.g. Read More