408,943 results match your criteria intensity 1000 µmol

Removed heavy metal ions from wastewater reuse for chemiluminescence: Successive application of lignin-based composite hydrogels.

J Hazard Mater 2021 Jul 24;421:126722. Epub 2021 Jul 24.

Liaoning Key Laboratory of Lignocellulosic Chemistry and Biomaterials, College of Light Industry and Chemical Engineering, Dalian Polytechnic University, Dalian 116034, China. Electronic address:

The novel sulfomethylated lignin-grafted-polyacrylic acid (SL-g-PAA) hydrogel was fabricated in this work via a facile and green synthetic strategy for the efficient removal of heavy metal ions from wastewater, and then successively reused for chemiluminescence (CL). The sulfomethylation of lignin was first performed to improve its water solubility and introduce numerous active sites for adsorption of heavy metal ions. The as-synthesized SL-g-PAA hydrogel with high content of lignin exhibited the highly efficient and rapid removal of various metal ions from simulated wastewater. Read More

View Article and Full-Text PDF

Simultaneous nitrification and aerobic denitrification by a novel isolated Ochrobactrum anthropi HND19.

Bioresour Technol 2021 Jul 16;340:125582. Epub 2021 Jul 16.

State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China.

The study aimed to isolate a novel strain with heterotrophic nitrification and aerobic denitrification ability and evaluate the nitrogen removal characteristics. Results showed that Ochrobactrum anthropi HND19 could remove approximately 98.6% of NH-N (104. Read More

View Article and Full-Text PDF

Environmental sustainability of a pork and bean stew.

Sci Total Environ 2021 Jul 26;798:149203. Epub 2021 Jul 26.

School of Industrial Engineering (ETSII), C/José Gutiérrez Abascal, 2, Grupo de Agroenergética, Universidad Politécnica de Madrid, Madrid 28006, Spain.

The aim of this investigation is to quantify the environmental footprint of an industrially produced bean and pork stew produced using a combination of local/imported and fresh/ processed ingredients. The study describes 16 midpoint categories and an aggregated score, calculated following the EC Product Environmental Footprint (PEF) methodology. The carbon footprint of 1 kg of stew amounts to 2. Read More

View Article and Full-Text PDF

Individual conscious and unconscious perception of emotion: Theory, methodology and applications.

Conscious Cogn 2021 Jul 28;94:103172. Epub 2021 Jul 28.

School of Social Sciences, Nottingham Trent University, United Kingdom.

In this manuscript we review a seminal debate related to subliminality and concerning the relationship of consciousness, unconsciousness, and perception. We present the methodological implementations that contemporary psychology introduced to explore this relationship, such as the application of unbiased self-report metrics and Bayesian analyses for assessing detection and discrimination. We present evidence concerning an unaddressed issue, namely, that different participants and stimulus types require different thresholds for subliminal presentation. Read More

View Article and Full-Text PDF

Accelerated theta burst stimulation for the treatment of depression: A randomised controlled trial.

Brain Stimul 2021 Jul 28. Epub 2021 Jul 28.

Epworth Centre for Innovation in Mental Health, Epworth Healthcare and Department of Psychiatry, Monash University, Camberwell, Victoria, Australia.

Introduction: Theta burst pattern repetitive transcranial magnetic stimulation (TBS) is increasingly applied to treat depression. TBS's brevity is well-suited to application in accelerated schedules. Sizeable trials of accelerated TBS are lacking; and optimal TBS parameters such as stimulation intensity are not established. Read More

View Article and Full-Text PDF

Affinity proteomics and deglycoproteomics uncover novel EDEM2 endogenous substrates and an integrative ERAD network.

Mol Cell Proteomics 2021 Jul 28:100125. Epub 2021 Jul 28.

Department of Molecular Cell Biology, Institute of Biochemistry, Splaiul Independenței 296, 060031, Bucharest, Romania. Electronic address:

Various pathologies result from disruptions to or stress of endoplasmic reticulum (ER) homeostasis, such as Parkinson's disease and most neurodegenerative illnesses, diabetes, pulmonary fibrosis, viral infections and cancers. A critical process in maintaining ER homeostasis is the selection of misfolded proteins by the ER quality-control system (ERQC) for destruction via ER-associated degradation (ERAD). One key protein proposed to act during the first steps of misfolded glycoprotein degradation is the ER degradation-enhancing α-mannosidase-like protein 2 (EDEM2). Read More

View Article and Full-Text PDF

The Clinical Use of Curcumin for the Treatment of Recurrent Aphthous Stomatitis: A Systematic Review of Clinical Trials.

Adv Exp Med Biol 2021 ;1291:229-238

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Recurrent aphthous stomatitis (RAS) lesions are inflammatory painful oral ulcers with uncertain etiology. Curcumin acts as an effective anti-inflammatory and antibacterial agent in the treatment of various oral diseases. This systematic review aimed to assess the effects of curcumin on RAS. Read More

View Article and Full-Text PDF
January 2021

Exploring the relationship between economic growth, energy consumption, urbanization, trade, and CO emissions: a PMG-ARDL panel data analysis on regional classification along 81 BRI economies.

Environ Sci Pollut Res Int 2021 Jul 31. Epub 2021 Jul 31.

National Commission for Tertiary Education, Accra, Ghana.

The vision of every country or sub-regions is to achieve sustainable economic growth. The inability of individual countries to have a sole sustainable initiative has resulted in the establishment of economic cooperation such as the Belt and Road Initiative (BRI), which renders interaction among 138 relevant countries to increase economic development. This study delves into the determinants of economic growth along the BRI economic corridors, taking into consideration regional classification of the relevant countries. Read More

View Article and Full-Text PDF

The empirical decomposition and peak path of China's tourism carbon emissions.

Environ Sci Pollut Res Int 2021 Jul 31. Epub 2021 Jul 31.

School of Statistics, Dongbei University of Finance and Economics, Dalian, 116025, China.

Carbon emissions from tourism are an important indicator to measure the impact of tourism on environmental quality. As the world's largest industry, tourism has many related industries and is a strong driver of energy consumption. The emission reductions it can achieve will directly determine whether China's overall carbon emission reduction target can be met. Read More

View Article and Full-Text PDF

Mitochondrial content, activity, and morphology in prepubertal and adult human ovaries.

J Assist Reprod Genet 2021 Jul 31. Epub 2021 Jul 31.

Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale Et Clinique, Université Catholique de Louvain, Avenue Mounier 52, bte. B1.52.02, 1200, Brussels, Belgium.

Purpose: To investigate whether mitochondrial content, activity, and morphology differ in prepubertal versus adult ovarian follicles.

Methods: Ovarian tissue was collected from 7 prepubertal girls (age 1-10 years) and 6 adult women (age 20-35 years). Primordial and primary follicles were isolated from frozen-thawed prepubertal and adult ovarian tissue and their viability was assessed. Read More

View Article and Full-Text PDF

Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.

J Cell Mol Med 2021 Jul 31. Epub 2021 Jul 31.

The College of Exercise Medicine, Chongqing Medical University, Chongqing, China.

We aimed to study the effects and underlying mechanism of different intensities of continuous training (CT) on vascular inflammation and oxidative stress in spontaneously hypertensive rats (SHR). Rats were divided into five groups (n = 12): Wistar-Kyoto rats sedentary group (WKY-S), sedentary group (SHR-S), low-intensity CT group (SHR-L), medium-intensity CT group (SHR-M) and high-intensity CT group (SHR-H). Changes in body mass, heart rate and blood pressure were recorded. Read More

View Article and Full-Text PDF

Prevalence of metachronous contralateral mature ovarian teratoma: A systematic review.

Pediatr Blood Cancer 2021 Jul 31:e29237. Epub 2021 Jul 31.

University Hospital Southampton NHS Foundation Trust, Southampton, UK.

There is increasing recognition that contralateral metachronous tumor may occur following treatment of unilateral mature ovarian teratoma. We aimed to define this risk to guide appropriate surveillance strategies. We undertook a systematic review of three large medical databases (Ovid Medline, Embase, and Cochrane Controlled Trials Register) to April 2020 using a defined search strategy. Read More

View Article and Full-Text PDF

Statin use and survival in 16 098 patients with non-Hodgkin lymphoma or chronic lymphocytic leukaemia treated in the rituximab era.

Br J Haematol 2021 Jul 31. Epub 2021 Jul 31.

Department of Medicine, Division of Hematology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.

Statin use has been associated with reduced mortality from several cancers but also suggested, in vitro, to diminish the effectiveness of lymphoma treatments including rituximab. The present study aimed to assess the association of statin use with mortality in patients with non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL). We identified all incident NHLs and CLLs in Sweden from 2007 to 2013 with subtype information in the Swedish Lymphoma and Cancer Registers. Read More

View Article and Full-Text PDF

Exploring The Interactions of a Natural Gamma-Oryzanol with Human Serum Albumin: Surface Plasmon Resonance, Fluorescence, and Molecular Modeling Studies.

Drug Res (Stuttg) 2021 Jul 30. Epub 2021 Jul 30.

Pharmaceutical Sciences Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.

γ-oryzanol (ORY) is the vital bioactive compound, which is a mixture of ferulic acid ester and plant sterols. In the present work, the binding of ORY to human serum albumin (HSA) was investigated at the molecular level using fluorescence spectroscopy and surface plasmon resonance (SPR) as well as molecular modeling studies. Based on the fluorescence data analysis, ORY can form a non-fluorescent complex with HSA and induce static quenching of the emission intensity of HSA. Read More

View Article and Full-Text PDF

Multiplexed Imaging of Posttranslational Modifications of Endogenous Proteins in Live Cells.

Methods Mol Biol 2021 ;2350:31-41

Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Tokyo, Japan.

Posttranslational histone modifications are associated with the regulation of genome function. Some modifications are quite stable to maintain epigenome states of chromatin, and others can exhibit dynamic changes in response to internal and external stimuli. To track the local and global changes in histone modifications, multiplexed imaging in living cells is beneficial. Read More

View Article and Full-Text PDF
January 2021

Surface-enhanced Raman spectroscopy aptasensor for simultaneous determination of ochratoxin A and zearalenone using [email protected] core-shell nanoparticles and gold nanorods.

Mikrochim Acta 2021 Jul 31;188(8):281. Epub 2021 Jul 31.

Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Tianjin Institute of Environmental and Operational Medicine, Tianjin, 300050, China.

The design and fabrication of a surface-enhanced Raman scattering (SERS) aptasensor for simultaneous detection of zearalenone (ZEN) and ochratoxin A (OTA) in wheat and corn samples is described. The capture and reporter probes were SH-cDNA-modified gold nanorods and SH-Apt-modified [email protected] core-shell nanoparticles, respectively. After recognizing OTA and ZEN aptamers and complementary strands (SH-cDNA), the reporter probe generated a strong SERS signal. Read More

View Article and Full-Text PDF

SERS-ELISA determination of human carboxylesterase 1 using metal-organic framework doped with gold nanoparticles as SERS substrate.

Mikrochim Acta 2021 Jul 30;188(8):280. Epub 2021 Jul 30.

Guangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, No.268 Donghuan Road, Chengzhong District, Liuzhou City, 545006, Guangxi Zhuang Autonomous Region, China.

By in situ synthesis of gold nanoparticles (AuNPs) within the acid-etched (AE) MIL-101 (Cr) framework, AE-MIL-101 (Cr) nanocomposites embedded with AuNPs (AuNP/AE-MIL-101 (Cr)) were prepared as surface-enhanced Raman scattering (SERS) substrate. AuNPs are uniformly distributed and stabilized inside the metal-organic framework (MOF), thus forming more SERS hotspots. The SERS performance of AuNP/AE-MIL-101 (Cr) was evaluated using 4-mercaptophenylboronic acid (4-MPBA), 4-mercaptobenzoic acid (4-MBA), benzidine, and rhodamine 6G (R6G). Read More

View Article and Full-Text PDF

Treatment strategies and outcomes for elderly patients with locally advanced squamous cell carcinoma of the esophagus.

Surg Today 2021 Jul 30. Epub 2021 Jul 30.

Department of Gastroenterological Surgery, Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.

Purpose: A multidisciplinary treatment strategy for locally advanced esophageal squamous cell carcinoma (ESCC) is required to achieve prolonged survival. We aimed to clarify the differences in treatment strategies for locally advanced ESCC and the outcomes of elderly (aged ≥ 75 years) vs. younger patients (aged < 75 years). Read More

View Article and Full-Text PDF

Hydralazine augmented ultrasound hyperthermia for the treatment of hepatocellular carcinoma.

Sci Rep 2021 Jul 30;11(1):15553. Epub 2021 Jul 30.

Ultrasound Research Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA, 19104, USA.

This study investigates the use of hydralazine to enhance ultrasound hyperthermia for the treatment of hepatocellular carcinoma (HCC) by minimizing flow-mediated heat loss from the tumor. Murine HCC tumors were treated with a continuous mode ultrasound with or without an intravenous administration of hydralazine (5 mg/kg). Tumor blood flow and blood vessels were evaluated by contrast-enhanced ultrasound (CEUS) imaging and histology, respectively. Read More

View Article and Full-Text PDF

Badland landscape response to individual geomorphic events.

Nat Commun 2021 Jul 30;12(1):4631. Epub 2021 Jul 30.

Department of Civil Engineering, National Taipei University of Technology, Taipei, Taiwan (R.O.C.).

Landscapes form by the erosion and deposition of sediment, driven by tectonic and climatic forcing. The principal geomorphic processes of badland - landsliding, debris flow and runoff erosion - are similar to those in full scale mountain topography, but operate faster. Here, we show that in the badlands of SW Taiwan, individual rainfall events cause quantifiable landscape change, distinct for the type of rainfall. Read More

View Article and Full-Text PDF

Fli1 cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis.

Proc Natl Acad Sci U S A 2021 Aug;118(31)

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX 77030.

A network of molecular factors drives the development, differentiation, and maintenance of endothelial cells. Friend leukemia integration 1 transcription factor (FLI1) is a bona fide marker of endothelial cells during early development. In zebrafish , we identified two endothelial cell populations, high- and low- , by the intensity of green fluorescent protein signal. Read More

View Article and Full-Text PDF

No additional effects of ursolic acid supplementation associated with combined exercise program on metabolic syndrome of postmenopausal women: A double-blind, randomized, placebo-controlled trial.

Clin Nutr ESPEN 2021 Aug 19;44:143-149. Epub 2021 Jun 19.

Post-Graduate Program in Human Movement Sciences, Methodist University of Piracicaba (UNIMEP), Piracicaba, SP, Brazil. Electronic address:

Background & Aims: Ursolic acid (UA) supplementation may have therapeutic effects on metabolic syndrome (MetS). Therefore, this study aimed to investigate the effects of UA supplementation associated with a combined exercise program on MetS components in postmenopausal women.

Methods: Twenty-six women (61 ± 7 years) were randomized into two groups: UA (n = 13) and placebo (PLA, n = 13). Read More

View Article and Full-Text PDF

Engagement in cognitively stimulating activities in individuals with Mild Cognitive Impairment: relationships with neuropsychological domains and hippocampal volume.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2021 Jul 30:1-22. Epub 2021 Jul 30.

Healthy Brain Ageing Program, Brain and Mind Centre, University of Sydney, Australia.

Late-life participation in cognitively stimulating activities is thought to contribute to an individual's cognitive reserve and thus protect against cognitive decline, yet its association with clinical markers of neurodegeneration is not well established. To investigate, we developed a 13-item self-report "cognitively stimulating activities" questionnaire (CSA-Q), which was completed by a community sample of 269 older adults (>50 years) at risk of dementia. Participants met criteria for Mild Cognitive Impairment (MCI) and were classified as amnestic (aMCI; = 93) or non-amnestic (naMCI; = 176). Read More

View Article and Full-Text PDF

Ratiometric fluorescence and smartphone dual-mode detection of glutathione using carbon dots coupled with Ag+-triggered oxidation of o-phenylenediamine.

Nanotechnology 2021 Jul 30. Epub 2021 Jul 30.

College of Chemistry and Materials Science, Anhui Normal University, Huajin campus of Anhui Normal University, 189 Jiuhua South Road, Yijiang District, Wuhu City, Anhui Province, Wuhu, 241002, CHINA.

Developing ratiometric fluorescence and smartphone dual-mode bioanalysis methods is important but challenging. A ratiometric fluorescence method for determining glutathione (GSH) using carbon dots (CDs) and Ag+-triggered o‑phenylenediamine (OPD) oxidation is described here. Ag+ oxidizes OPD to give 2,3-diaminophenazine (oxOPD), which effectively quenches CD fluorescence at 436 nm through the inner filter effect and causes a new emission peak at 561 nm. Read More

View Article and Full-Text PDF

Characterization of the structural and dynamic changes of cell wall obtained by ultrasound-water and ultrasound-alkali treatments.

Ultrason Sonochem 2021 Jul 18;77:105672. Epub 2021 Jul 18.

Beijing Key Laboratory of Wood Science and Engineering, College of Material Science and Technology, Beijing Forestry University, No. 35 Tsinghua East Road Haidian District, Beijing, PR China. Electronic address:

It is well-known that ultrasound has been studied for its cavitation, mechanical and thermal effects. As a pretreatment technology, ultrasonic alkali treatment has attracted much attention in the field of biomass biochemical transformation. In this study, the structural and dynamic changes of wood cell walls during ultrasound-water, alkali, and ultrasound-alkali treatments were investigated by stereoscopic microscopy, confocal Raman microscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction. Read More

View Article and Full-Text PDF

Hepatic actinomycosis after total pancreatectomy: A case report.

Int J Surg Case Rep 2021 Jul 20;85:106212. Epub 2021 Jul 20.

Department of Surgery, Kansai Medical University, Osaka, Japan.

Introduction And Importance: Hepatic actinomycosis (HA) is a rare infection mimicking a malignancy. HA after total pancreatectomy for a pancreatic tumor has not been reported.

Case Presentation: A 70-year-old woman with a history of gastrectomy and sigmoidectomy for benign lesions, underwent a total pancreatectomy for a non-invasive, intraductal papillary mucinous carcinoma (IPMC). Read More

View Article and Full-Text PDF

Characterization of PFOS toxicity on in-vivo and ex-vivo mouse pancreatic islets.

Environ Pollut 2021 Jul 26;289:117857. Epub 2021 Jul 26.

Croucher Institute for Environmental Sciences, Department of Biology, Hong Kong Baptist University, Hong Kong SAR, China. Electronic address:

Considerable human data have shown that the exposure to perfluorooctane sulfonate (PFOS) correlates to the risk of metabolic diseases, however the underlying effects are not clearly elucidated. In this study, we investigated the impacts of PFOS treatment, using in-vivo, ex-vivo and in-vitro approaches, on pancreatic β-cell functions. Mice were oral-gavage with 1 and 5 μg PFOS/g body weight/day for 21 days. Read More

View Article and Full-Text PDF

Predicting biomass and hydrocarbon productivities and colony size in continuous cultures of Botryococcus braunii showa.

Bioresour Technol 2021 Jul 24;340:125653. Epub 2021 Jul 24.

Wageningen University, Bioprocess Engineering, AlgaePARC, PO Box 16, 6700 AA, Wageningen, the Netherlands.

Mathematical models were developed to predict biomass and hydrocarbon productivities and colony size (ouputs) of Botryococcus braunii showa cultures based on light intensity, temperature and dilution rate (inputs). These models predicted the following maximum values: biomass productivity, 1.3 g L d; hydrocarbon productivity, 1. Read More

View Article and Full-Text PDF

Dynamics of urban landscape nexus spatial dependence of ecosystem services in rapid agglomerate cities of Ethiopia.

Sci Total Environ 2021 Jul 23;798:149192. Epub 2021 Jul 23.

Addis Ababa University, Center for Environmental Science, Ethiopia.

Understanding the dependence of ecosystem services (ESs) on the dynamics of human-semi nature-coupled ecosystems is crucial for urban ecosystem resilience. In the present study, the responses of ESs to land use land cover transitions were explored and compared, selecting Addis Ababa, Adama, Hawassa, and Bahir Dar cities in Ethiopia. The geospatial data and benefit transfer approach was used to estimate the nexus over a three-decade period (1990-2020). Read More

View Article and Full-Text PDF

Microbial biofilm community dynamics in five lowland streams.

Sci Total Environ 2021 Jul 20;798:149169. Epub 2021 Jul 20.

Department of Biology, Aarhus University, Ole Worms Allé 1, 8000 Aarhus, Denmark; WATEC, Aarhus University, Centre for Water Technology, 8000 Aarhus, Denmark.

Stream biofilms are complex aggregates of diverse organism groups that play a vital role in global carbon and nitrogen cycles. Most of the current studies on stream biofilm focus on a limited number of organism groups (e.g. Read More

View Article and Full-Text PDF