Bioorg Med Chem Lett 2021 Jun 9:128192. Epub 2021 Jun 9.
Medicinal Plants Research Center - NPPM, Federal University of Piauí, UFPI, 64049-550 Teresina, PI, Brazil; Center of Agricultural Sciences, Department of Veterinary Morphophysiology, Federal University of Piauí, UFPI, 64049-550 Teresina, PI, Brazil. Electronic address:
In this study, we analyzed the antimicrobial, antibiofilm, and modulatory activities of trans-trans-farnesol (tt-farnesol). The minimum inhibitory concentration (MIC) of this sesquiterpene was evaluated against 31 Gram-positive and Gram-negative bacterial strains and 4 species of the genus Candida. Furthermore, we examined its inhibitory action on biofilm production as well as antibiotic modulation. Read More