101,241 results match your criteria insecureresults synergistic

Generation of hydroxyl radicals by metal-free bifunctional electrocatalysts for enhanced organics removal.

Sci Total Environ 2021 May 31;791:148107. Epub 2021 May 31.

Guangdong Key Laboratory of Environmental Pollution and Health, School of Environment, Jinan University, Guangzhou 511443, China. Electronic address:

Low yields of HO and a narrow range of appropriate pH values have been two major drawbacks for electro-Fenton (EF) process. Herein, metal-free electrochemical advanced oxidation processes (EAOPs) were developed with nitrogen and sulfur co-doped electrochemically exfoliated graphene (N, S-EEGr) electrocatalysts, which was confirmed as an outstanding bifunctional catalyst for synchronous generation and activation of HO via (2 + 1) e consecutive reduction reactions. Specifically, two elements (N, S) in metal-free N, S-EEGr-CF cathode synergize to promote the formation of HO followed by its activation. Read More

View Article and Full-Text PDF

Production of an electro-biological particle electrode (EBPE) from lithium slag and its removal performance to salicylic acid in a three-dimensional electrocatalytic biological coupling reactor (3D-EBCR).

Chemosphere 2021 Jun 2;282:131020. Epub 2021 Jun 2.

School of Civil Engineering and Architecture, University of Jinan, Jinan, 250022, China.

Electro-biological particle electrode (EBPE) prepared by lithium slag was used to remove salicylic acid in a three-dimensional electrocatalytic biological coupling reactor (3D-EBCR). The physical and chemical properties of the EBPE, the removal performance of salicylic acid and the degradation mechanism were studied. Results revealed as follows: (1) the EBPE prepared by lithium slag contained effective catalytic components including FeO, SnO, ZnO, MnO, RbO and TiO, with stable structure and good adsorption performance; (2) the 3D-EBCR with EBPE had strong adaptability to the current intensity in the range of 0. Read More

View Article and Full-Text PDF

Mixed biochar obtained by the co-pyrolysis of shrimp shell with corn straw: Co-pyrolysis characteristics and its adsorption capability.

Chemosphere 2021 Jun 5;282:131116. Epub 2021 Jun 5.

College of Environment and Safety Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China. Electronic address:

The co-pyrolysis characteristics of shrimp shell (SS) with corn straw (CS) were investigated by comprehensive characterization to reveal the synergistic effects and further discuss the adsorption capability. TGA results showed that pyrolysis behavior and reactivity were improved with the increase of heating rate and doping ratio of CS. Flynn-Wall-Ozawa (FWO) and distributed activation energy model (DAEM) indicated that co-pyrolysis can effectively reduce energy consumption and promote the decomposition of CaCO. Read More

View Article and Full-Text PDF

Loss of ATRX confers DNA repair defects and PARP inhibitor sensitivity.

Transl Oncol 2021 Jun 9;14(9):101147. Epub 2021 Jun 9.

Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06511, USA. Electronic address:

Alpha Thalassemia/Mental Retardation Syndrome X-Linked (ATRX) is mutated frequently in gliomas and represents a potential target for cancer therapies. ATRX is known to function as a histone chaperone that helps incorporate histone variant, H3.3, into the genome. Read More

View Article and Full-Text PDF

New concept in swine wastewater treatment: development of a self-sustaining synergetic microalgae-bacteria symbiosis (ABS) system to achieve environmental sustainability.

J Hazard Mater 2021 Jun 3;418:126264. Epub 2021 Jun 3.

State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, PR China. Electronic address:

Much attention has been paid to developing methods capable of synchronous removal of pollutants from swine wastewater. Due to the natural symbiotic interactions between microalgae and bacteria, the microalgae-bacteria symbiosis (ABS) system has been found to have potential for treating wastewater. However, the corresponding biological mechanisms in the ABS system and the role of dynamic microbial community evolution in pollutant removal systems remain poorly understood. Read More

View Article and Full-Text PDF

A biomimetic triple-layered biocomposite with effective multifunction for dura repair.

Acta Biomater 2021 Jun 9. Epub 2021 Jun 9.

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China. Electronic address:

Dura mater defect and subsequent cerebrospinal fluid (CSF) leakage usually appear in trauma or neurosurgical procedures and are followed by a series of serious complications and even death. The use of a qualified dura mater substitute with multifunction of leakage blockade, adhesion prevention, and dura reconstruction is one of the promising treatment methods. However, even though some products have been used in the clinic, none of the substitutes achieved the required multifunction. Read More

View Article and Full-Text PDF

Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health.

Bioorg Med Chem Lett 2021 Jun 9:128192. Epub 2021 Jun 9.

Medicinal Plants Research Center - NPPM, Federal University of Piauí, UFPI, 64049-550 Teresina, PI, Brazil; Center of Agricultural Sciences, Department of Veterinary Morphophysiology, Federal University of Piauí, UFPI, 64049-550 Teresina, PI, Brazil. Electronic address:

In this study, we analyzed the antimicrobial, antibiofilm, and modulatory activities of trans-trans-farnesol (tt-farnesol). The minimum inhibitory concentration (MIC) of this sesquiterpene was evaluated against 31 Gram-positive and Gram-negative bacterial strains and 4 species of the genus Candida. Furthermore, we examined its inhibitory action on biofilm production as well as antibiotic modulation. Read More

View Article and Full-Text PDF

Combination of copigmentation and encapsulation strategies for the synergistic stabilization of anthocyanins.

Compr Rev Food Sci Food Saf 2021 Jun 12. Epub 2021 Jun 12.

Department of Food Science, Cornell University, Stocking Hall, Ithaca, New York, USA.

Copigmentation and encapsulation are the two most commonly used techniques for anthocyanin stabilization. However, each of these techniques by itself suffers from many challenges associated with the simultaneous achievement of color intensification and high stability of anthocyanins. Integrating copigmentation and encapsulation may overcome the limitation of usage of a single technique. Read More

View Article and Full-Text PDF

Synergistic effect of docosahexaenoic acid or conjugated linoleic acid with caffeic acid on ameliorating oxidative stress of HepG2 cells.

J Food Sci 2021 Jun 12. Epub 2021 Jun 12.

College of Food Science, Shenyang Agricultural University, Shenyang, P.R. China.

Exploring the synergistic effect of docosahexaenoic acid (DHA) or conjugated linoleic acid (CLA) with caffeic acid (CA) on ameliorating oxidative stress, thereby introducing CA to DHA or CLA will contribute significantly to enhance the bioactivity. We observed that DHA or CLA with CA promoted the recovery of intact individual morphology and the decline of cavities inside the nucleus and apoptosis under the observation of confocal laser scanning microscopy and fluorescent inverted microscope. The activity of intracellular antioxidant enzymes catalase (CAT) and glutathione peroxidase (GSH-Px), lactate dehydrogenase (LDH) leakage, pyruvate and malondialdehyde and reactive oxygen species (ROS), cellular morphology, and cell cycle were analyzed. Read More

View Article and Full-Text PDF

Changing light promotes isoflavone biosynthesis in soybean pods and enhances their resistance to mildew infection.

Plant Cell Environ 2021 Jun 12. Epub 2021 Jun 12.

Institute of Ecological Agriculture, Sichuan Agricultural University, Chengdu, Sichuan, China.

Mildew severely reduces soybean yield and quality, and pods are the first line of defense against pathogens. Maize-soybean intercropping (MSI) reduces mildew incidence on soybean pods; however, the mechanism remains unclear. Changing light (CL) from maize shading is the most important environmental feature in MSI. Read More

View Article and Full-Text PDF

Food Should not be Forgotten: Impacts of Combined Cash Transfer Receipt and Food Security on Child Education and Cognition in South Africa and Malawi.

AIDS Behav 2021 Jun 11. Epub 2021 Jun 11.

Centre for Evidence-Based Intervention, Department of Social Policy & Intervention, University of Oxford, Oxford, UK.

Social protection can take many forms. Both cash transfers and food security may have important contributions to child cognitive development. This study examines the potential impact of combinations of cash transfers and food security status on child cognitive development and educational outcomes. Read More

View Article and Full-Text PDF

The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers.

Oncogene 2021 Jun 11. Epub 2021 Jun 11.

Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Osaka University, Suita, Japan.

Dickkopf1 (DKK1) is overexpressed in various cancers and promotes cancer cell proliferation by binding to cytoskeleton-associated protein 4 (CKAP4). However, the mechanisms underlying DKK1 expression are poorly understood. RNA sequence analysis revealed that expression of the transcription factor forkhead box M1 (FOXM1) and its target genes concordantly fluctuated with expression of DKK1 in pancreatic ductal adenocarcinoma (PDAC) cells. Read More

View Article and Full-Text PDF

HSP-90/kinase complexes are stabilized by the large PPIase FKB-6.

Sci Rep 2021 Jun 11;11(1):12347. Epub 2021 Jun 11.

Department of Chemistry, Center for Integrated Protein Research, Technische Universität München, Lichtenbergstr. 4, 85748, Garching, Germany.

Protein kinases are important regulators in cellular signal transduction. As one major type of Hsp90 client, protein kinases rely on the ATP-dependent molecular chaperone Hsp90, which maintains their structure and supports their activation. Depending on client type, Hsp90 interacts with different cofactors. Read More

View Article and Full-Text PDF

Biochar induced improvement in root system architecture enhances nutrient assimilation by cotton plant seedlings.

BMC Plant Biol 2021 Jun 11;21(1):269. Epub 2021 Jun 11.

College of Natural Resources and Environment, Northwest Key Laboratory of Plant Nutrition and Agro-Environment, Ministry of Agriculture, Northwest A & F University, Yangling, 712100, China.

Background: Raising nitrogen use efficiency of crops by improving root system architecture is highly essential not only to reduce costs of agricultural production but also to mitigate climate change. The physiological mechanisms of how biochar affects nitrogen assimilation by crop seedlings have not been well elucidated.

Results: Here, we report changes in root system architecture, activities of the key enzymes involved in nitrogen assimilation, and cytokinin (CTK) at the seedling stage of cotton with reduced urea usage and biochar application at different soil layers (0-10 cm and 10-20 cm). Read More

View Article and Full-Text PDF

Enhanced electrochemical properties of Ni-rich layered cathode materials via Mg and Tico-doping for lithium-ion batteries.

J Colloid Interface Sci 2021 May 29;601:853-862. Epub 2021 May 29.

College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, PR China. Electronic address:

To optimize the electrochemical performance of Ni-rich cathode materials, the 0.005 mol of Mg and 0.005 mol of Tico-doping LiNiCoMnO composite powders, labeled as NCM-11, are successfully prepared by being calcinated at 750 °C for 15 h following by an appropriate post-treatment, which are confirmed by XRD, EDS and XPS. Read More

View Article and Full-Text PDF

Effect of pre-strain on microstructure and micro-yield properties of Al-Cu-Li alloy.

Micron 2021 Jun 8;148:103092. Epub 2021 Jun 8.

Key Laboratory of Material Physics, Ministry of Education, School of Physics and Microelectronics, Zhengzhou University, Zhengzhou, Henan Province, 450052, China.

In this study, Al-Cu-Li alloys were pre-strained to various plastic strains before ageing. The T1 (AlCuLi) precipitates and dislocation density in various pre-strained Al-Cu-Li alloys were analyzed with transmission electron microscopy (TEM) and X-ray diffraction (XRD) technology respectively. The micro-yield strength (Micro-YS) of tested alloys was measured and the strengthening mechanism was discussed. Read More

View Article and Full-Text PDF

Synergistic effects of plant growth promoting rhizobacteria and silicon dioxide nano-particles for amelioration of drought stress in wheat.

Plant Physiol Biochem 2021 Jun 4;166:160-176. Epub 2021 Jun 4.

Department of Botany, S.P. College, Srinagar, Jammu, and Kashmir, India.

Drought tolerant plant growth-promoting rhizobacteria (PGPR) can confer drought tolerance in plants, when inoculated, and this effect can be more pronounced by their combined application with silicon oxide nanoparticles (SiO NPs). In this research, drought-tolerant and plant growth-promoting rhizobacterial strains were isolated from the rhizospheric soil of wheat plants growing in the arid region of Pakistan. Out of 30 isolated strains, three rhizobacterial strains were selected based on their drought tolerance, higher phytohormones (indole acetic acid (IAA), abscisic acid (ABA), and cytokinin (CK), and osmolyte (proline and sugar) production ability. Read More

View Article and Full-Text PDF

NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy.

Biomaterials 2021 May 31;275:120935. Epub 2021 May 31.

State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, Nanjing, 210023, China; Frontiers Science Center for Flexible Electronics (FSCFE), MIIT Key Laboratory of Flexible Electronics (KLoFE), Northwestern Polytechnical University, Xi'an, 710072, China. Electronic address:

Photothermal therapy (PTT) is hampered by limited light penetration depth and cell thermoresistance induced by over-expressed heat shock proteins (HSPs). Herein, we proposed a tumor-specific enhanced NIR-II PTT through the starvation mediated thermal sensitization strategy. A semiconducting polymer with superior NIR-II fluorescence imaging (FI) performance and NIR-II PTT efficacy was synthesized and encapsulated into folate modified liposomes, together with a glycolysis inhibitor, 2-deoxy-d-glucose (2DG). Read More

View Article and Full-Text PDF

The promotions on radical formation and micropollutant degradation by the synergies between ozone and chemical reagents (synergistic ozonation): A review.

J Hazard Mater 2021 Jun 8;418:126327. Epub 2021 Jun 8.

Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Institute of Environment and Ecology, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, China. Electronic address:

The combination of ozone (O) and chemical reagents (such as HO) shows synergies on the radical formation and micropollutant degradation. The promoting performance was associated with various parameters including chemical reagents, micropollutants, solution pH, and the water matrix. In this review, we summarized existing knowledge on radical formation pathways, radical yields, and radical oxidation for different synergistic ozonation processes in various water matrices (such as groundwater, surface water, and wastewater). Read More

View Article and Full-Text PDF

Characterising non-linear associations between airborne pollen counts and respiratory symptoms from the AirRater smartphone app in Tasmania, Australia: A case time series approach.

Environ Res 2021 Jun 8:111484. Epub 2021 Jun 8.

Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia; Public Health Services, Department of Health, Hobart, TAS, 7000, Australia. Electronic address:

Pollen is a well-established trigger of asthma and allergic rhinitis, yet concentration-response relationships, lagged effects, and interactions with other environmental factors remain poorly understood. Smartphone technology offers an opportunity to address these challenges using large, multi-year datasets that capture individual symptoms and exposures in real time. We aimed to characterise associations between six pollen types and respiratory symptoms logged by users of the AirRater smartphone app in Tasmania, Australia. Read More

View Article and Full-Text PDF

The memory for words: Armand Trousseau on aphasia.

Richard Leblanc

J Hist Neurosci 2021 Jun 11:1-19. Epub 2021 Jun 11.

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

Of all the nineteenth-century physicians whose names still resonate today, Armand Trousseau is perhaps the one most familiar, for his description of carpal spasm as a sign of hypocalcemia (Trousseau's sign) and his description of the hypercoagulable state associated with cancer (Trousseau's syndrome). In the last three years of his life, Trousseau turned his attention to aphasia, which he included in his 1864 and 1865 lectures given at Hôtel-Dieu Hospital in Paris and which he discussed in an address to the Imperial Academy of Medicine in 1865. Trousseau preceded Wernicke in describing aphasia as a symptom complex, in which he included Broca's aphemia, receptive aphasia, the inability to read with and without the inability to write (alexia with and without agraphia), the inability to name common objects (amnesic aphasia or anomia) and to recognize numbers (acalculia), and the inability to draw. Read More

View Article and Full-Text PDF

T-LAK cell-originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma.

Mol Oncol 2021 Jun 11. Epub 2021 Jun 11.

Department of Orthopaedic Surgery, Sarcoma Biology Laboratory, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

T-lymphokine-activated killer (T-LAK) cell-originated protein kinase (TOPK) is an emerging target with critical roles in various cancers; however, its expression and function in osteosarcoma remain unexplored. We evaluated TOPK expression using RNA sequencing and gene expression data from public databases (TARGET-OS, CCLE, GTEx and GENT2) and immunohistochemistry in an osteosarcoma tissue microarray (TMA). TOPK gene expression was significantly higher in osteosarcoma than normal tissues, and directly correlated with shorter overall survival. Read More

View Article and Full-Text PDF

Larvicidal potential of cell wall degrading enzymes from Trichoderma asperellum against Aedes aegypti (Diptera: Culicidae).

Biotechnol Prog 2021 Jun 11. Epub 2021 Jun 11.

Laboratório de Química de Polímeros (LQP) - ICB2 - Universidade Federal de Goiás, Goiânia, GO, Brazil.

Background: Aedes aegypti is a mosquito vector of arboviruses such as Dengue, Chikungunya, Zika and Yellow Fever that cause important public health diseases. The incidence and gravity of these diseases justifies the search for effective measures to reduce the presence of this vector in the environment. Bioinsecticides are an effective alternative method for insect control, with added ecological benefits such as biodegradability. Read More

View Article and Full-Text PDF

Antimicrobial effects of plant extracts against Clostridium perfringens with respect to food-relevant influencing factors.

J Food Prot 2021 Jun 11. Epub 2021 Jun 11.

LMU München: Ludwig-Maximilians-Universitat Munchen Schoenleutner Strasse 8 GERMANY Oberschleissheim 85764.

The application of plant extracts (PEs) could be a promising option to satisfy consumers' demand for natural additives to inhibit growth of variable pathogenic bacteria. Thus, the aim of this study was to develop a standardized microdilution method to examine the antimicrobial effects of ten hydrophilic plant extracts against two strains of C. perfringens facing various food-relevant influencing factors. Read More

View Article and Full-Text PDF

Synergistic photocatalytic activity of a combination of carbon nanotubes-graphene-nickel foam nanocomposites enhanced by dielectric barrier discharge plasma technology for water purification.

Water Sci Technol 2021 Jun;83(11):2762-2777

School of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China E-mail:

Degradation activity of plasma catalysis between dielectric barrier discharge (DBD) and carbon nanotubes-graphene-nickel foam (CNTs-G-Ni) has been studied in treatment of dye wastewater. CNTs-G-Ni was prepared through a two-step chemical vapor deposition (CVD) approach. The composite has been characterized by different techniques such as X-ray diffraction (XRD), scanning electron microscope (SEM) and Raman spectroscopy. Read More

View Article and Full-Text PDF

Leishmanicidal potentials of extract and its fractions on in a murine model: parasite burden, gene expression, and histopathological profile.

J Med Microbiol 2021 Jun;70(6)

Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Leishmaniasis is a neglected tropical and subtropical disease caused by over 20 protozoan species. Treatment of this complex disease with traditional synthetic drugs is a major challenge worldwide. Natural constituents are unique candidates for future therapeutic development. Read More

View Article and Full-Text PDF

Investigation on Al and AlO Coexist in BiVO for Efficient Methylene Blue Degradation: Insight into Surface States and Charge Separation.

Langmuir 2021 Jun 11. Epub 2021 Jun 11.

College of Chemistry, Jilin University, Changchun 130012, P. R. China.

A series of Al-doped BiVO composites have been synthesized via the hydrothermal method for methylene blue (MB) degradation application. The reasons for the improvement of photocatalytic performance was explained from the perspective of optics. Transient photovoltage (TPV) measurements suggested that the surface states have the priority to capture photogenerated carriers, and the AlO surface passivation layer can prolong the lifetime of charge carrier. Read More

View Article and Full-Text PDF

Flower-like Spherical α-Ni(OH)2 Derived NiP2 as Superior Anode Material of Sodium Ion Batteries.

Chem Asian J 2021 Jun 11. Epub 2021 Jun 11.

South China University of Technology, College of Environment and Energy, Wushan Road 381, 51064, Guangzhou, CHINA.

Transition metal phosphides (TMPs) are promising anode candidates for sodium-ion batteries, due to their high theoretical specific capacity and working potential. However, the low conductivity and excessive volume variation of TMPs during insertion/extraction of sodium ions results in a poor rate performance and long-term cycling stability, largely limiting their practical application. In this paper, the NiP 2 nanoparticles encapsulated in three-dimensional graphene (NiP 2 @rGO) were obtained from the flower-like sphericalα-Ni(OH) 2 by phosphating and carbon encapsulation processes. Read More

View Article and Full-Text PDF

PtM/MxBy (M=Ni, Co, Fe) Heterostructured Nanobundles as Advanced Electrocatalyst for Hydrogen Evolution Reaction.

Chemistry 2021 Jun 11. Epub 2021 Jun 11.

Soochow University, College of Chemistry, Chemical Engineering and Materials Science, Renai road Suzhou Industrial Park, No. 199, 215123, Suzhou, CHINA.

Optimizing the electronic and synergistic effect of hybrid electrocatalysts based on Pt and Pt-based nanocatalysts is of tremendous importance towards a superior hydrogen evolution performance under both acidic and alkaline conditions. However, developing an ideal Pt-based hydrogen evolution reaction (HER) electrocatalyst with moderated electronic structure as well as strong synergistic effect is still a challenge. Herein, we fabricated boron (B)-doped PtNi nanobundles by a two-step method using NaBH 4 as the boron resource to obtain PtNi/Ni 4 B 3 heterostructures with well-defined nanointerfaces between PtNi and Ni 4 B 3 , achieving an enhanced catalytic HER performance. Read More

View Article and Full-Text PDF

New insight into antimicrobial activities of Linaria ventricosa essential oil and its synergetic effect with conventional antibiotics.

Arch Microbiol 2021 Jun 11. Epub 2021 Jun 11.

Laboratory of Microbial Biotechnologies, Agrosciences and Environment, Faculty of Science, Semlalia University Cadi Ayyad, Marrakech, Morocco.

The purpose of the present study was to determine for the first time the volatile constituents, the antioxidant and antimicrobial activities of the essential oil (EO) of the endemic Moroccan Linaria ventricosa, alone or in combination with four known antibiotics. The major constituents were 2-methoxy-4-vinylphenol (17.4%), α-terpinene (13. Read More

View Article and Full-Text PDF