5,593 results match your criteria injection triamcinolone

Non-steroidal anti-inflammatory drugs (NSAIDs) for trigger finger.

Cochrane Database Syst Rev 2021 Apr 14;4:CD012789. Epub 2021 Apr 14.

Cochrane Singapore, Singapore, Singapore.

Background: Trigger finger is a common hand condition that occurs when movement of a finger flexor tendon through the first annular (A1) pulley is impaired by degeneration, inflammation, and swelling. This causes pain and restricted movement of the affected finger. Non-surgical treatment options include activity modification, oral and topical non-steroidal anti-inflammatory drugs (NSAIDs), splinting, and local injections with anti-inflammatory drugs. Read More

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The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.

Burns 2021 Feb 24. Epub 2021 Feb 24.

The Graduate School, Fujian Medical University, Fuzhou, China.

Background: Triamcinolone acetonide (TAC) is widely used for hypertrophic scars and keloids; however, TAC has variable efficacy and safety in different individuals.

Purpose: To evaluate the efficacy and safety of intralesional TAC for treatment of hypertrophic scars and keloids.

Data Sources: Searches of PubMed, EMBASE, the Cochrane Library, and ClinicalTrials. Read More

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February 2021

Development of Triamcinolone Acetonide-Loaded Microemulsion as a Prospective Ophthalmic Delivery System for Treatment of Uveitis: In Vitro and In Vivo Evaluation.

Pharmaceutics 2021 Mar 25;13(4). Epub 2021 Mar 25.

Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

Treatment of uveitis (i.e., inflammation of the uvea) is challenging due to lack of convenient ophthalmic dosage forms. Read More

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Safety and Tolerability of Topical Ophthalmic Triamcinolone Acetonide-Loaded Liposomes Formulation and Evaluation of Its Biologic Activity in Patients with Diabetic Macular Edema.

Pharmaceutics 2021 Mar 2;13(3). Epub 2021 Mar 2.

Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, P.C. 45138 Zapopan, Mexico.

Intravitreal injections (IVTs) of corticosteroids as triamcinolone acetonide (TA) are frequently used for the treatment of many vitreous and retinal disorders. However, IVTs are related to severe ocular complications. Lately, a topical ophthalmic TA-loaded liposomes formulation (TALF) was designed to transport TA into the posterior segment of the eye when instilled on the ocular surface. Read More

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Intra-Articular Slow-Release Triamcinolone Acetonide from Polyesteramide Microspheres as a Treatment for Osteoarthritis.

Pharmaceutics 2021 Mar 11;13(3). Epub 2021 Mar 11.

Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands.

Osteoarthritis (OA) is a common cause of pain and disability. Local corticosteroid injections are effective in treating OA pain and inflammation but are short-acting. Prolonged intra-articular (IA) corticosteroid exposure may even lead to cartilage deterioration. Read More

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A case of panuveitis and retinal vasculitis associated with pembrolizumab therapy for metastatic lung cancer.

Am J Ophthalmol Case Rep 2021 Jun 12;22:101072. Epub 2021 Mar 12.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Purpose: To report a case of panuveitis and retinal vasculitis associated with pembrolizumab therapy for metastatic lung cancer.

Observations: A 71-year-old man, who was diagnosed with metastatic lung cancer (squamous cell carcinoma), presented with blurry vision 2 weeks after the initiation of pembrolizumab monotherapy. His best-corrected visual acuity (BCVA) was 20/20 OU, and slitlamp examination revealed fine keratic precipitates, anterior chamber cells (1+) and flare (1+) in both eyes. Read More

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Anti-TB monotherapy for choroidal tuberculoma: an observational study.

Eye (Lond) 2021 Apr 1. Epub 2021 Apr 1.

LV Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.

Background: Choroidal tuberculoma is possibly the most unequivocal manifestation of ocular infection with Mycobacterium tuberculosis. Here, we investigate the need for adjunctive corticosteroids in the management of this infection. We have compared the efficacy of anti-tubercular therapy (ATT) with or without oral corticosteroids, in management of choroidal tuberculoma. Read More

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Infectious Uveitis after Local Steroid and/or Methotrexate Injections at A Tertiary Referral Center in New Zealand: A Case Series.

Ocul Immunol Inflamm 2021 Apr 1:1-5. Epub 2021 Apr 1.

Department of Ophthalmology, Auckland District Health Board, Auckland, New Zealand.

: Infectious uveitis is one of the most visually devastating causes of uveitis worldwide and accounts for 19.6% of all cases of uveitis in New Zealand. With the burgeoning use of intravitreal injections, there has been a commensurate increase in the number of injection-related complications and reports of infectious uveitis following their administration in recent years. Read More

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Observations on the Efficacy of Two Methods for the Treatment of Upper Eyelid Retraction in Thyroid-Associated Ophthalmopathy.

Biomed Res Int 2021 18;2021:9514279. Epub 2021 Mar 18.

Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China.

Objective: To observe the clinical efficacy of periocular injection of triamcinolone acetonide (TA) and subpalpebral injection of botulinum toxin type A (BTXA) for the treatment of thyroid-associated ophthalmopathy (TAO) with mild unilateral upper eyelid retraction.

Method: This was a prospective randomized controlled study. A total of 68 cases of stable thyroid-associated ophthalmopathy with mild upper eyelid retraction were collected at Hankou Aier Eye Hospital from Jan. Read More

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Intratympanic Triamcinolone Acetonide as a Salvage Treatment for Idiopathic Sudden Sensorineural Hearing Loss.

Audiol Neurootol 2021 Mar 31:1-10. Epub 2021 Mar 31.

Department of Otorhinolaryngology, Medical University of Graz, Graz, Austria.

Introduction: Intratympanic steroid (ITS) injections represent an increasingly used salvage treatment option for patients with idiopathic sudden sensorineural hearing loss -(ISSHL) after systemic treatment. The most effective corticosteroid for this treatment modality still remains unclear. Triamcinolone acetonide has been used for ITS treatment in various clinical settings. Read More

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Efficacy and safety of suprachoroidal triamcinolone injection in horses with poorly responsive equine recurrent uveitis.

Vet Ophthalmol 2021 Mar 31. Epub 2021 Mar 31.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.

Objective: Equine recurrent uveitis (ERU), a chronic, immune-mediated intraocular inflammatory disease, is a common cause of blindness in horses. The severity and recurrent nature of ERU makes it difficult to treat with current therapeutics leading to a poor visual prognosis. The suprachoroidal space (SCS), a potential space between the choroid and sclera surrounding the ocular posterior segment, offers a promising alternative site for drug application to the eye. Read More

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A Comparison of Genicular Nerve Blockade With Corticosteroids Using Either Classical Anatomical Targets vs Revised Targets for Pain and Function in Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial.

Pain Med 2021 Mar 27. Epub 2021 Mar 27.

Neuro-Musculo-Skeletal pole (NMSK) - Experimental and clinical research institute (IREC), Université catholique de Louvain (UCLouvain), Brussels, Belgium.

Objective: Compare the effectiveness of genicular nerve blockade (GNB) using classical anatomical targets (CT) versus revised targets (RT) in patients suffering from chronic knee osteoarthritis pain.

Design: Double-blinded randomized controlled trial.

Setting: Pain medicine center of a teaching hospital. Read More

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Fungal abscess after intra-orbital steroid injection: a case report.

Orbit 2021 Mar 26:1-5. Epub 2021 Mar 26.

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

A 28-year-old male presented with gradually progressive swelling of the right lower eyelid along with a prominence of the eye for 6 months. He had received oral steroids and intraorbital triamcinolone acetonide injection in the inferior quadrant for active thyroid eye disease. External examination revealed right eye proptosis and swelling along the inferior orbital region. Read More

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Bevacizumab for diabetic macular oedema: one-year treatment outcomes from the Fight Retinal Blindness! Registry.

Eye (Lond) 2021 Mar 25. Epub 2021 Mar 25.

Save Sight Institute, Discipline of Ophthalmology and Eye Health, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

Objectives: This study evaluated the 1-year treatment outcomes of bevacizumab for diabetic macular oedema (DMO) in routine clinical practice.

Methods: A retrospective analysis was performed on 298 eyes of 220 patients with DMO that received intra-vitreal bevacizumab between 1 September 2013 and 31 August 2018 that were tracked by a prospectively designed, web-based observational registry-the Fight Retinal Blindness! Registry.

Results: The mean visual acuity (95% confidence interval [CI]) at 1-year was 3 (2, 5) letters better than a mean (SD) of 68 (15) letters at study entry. Read More

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Does Choice of Steroid Matter for Treatment of Chronic Low Back Pain with Sacroiliac Joint Injections: a Retrospective Study.

Curr Pain Headache Rep 2021 Mar 24;25(5):34. Epub 2021 Mar 24.

Department of Anesthesia, Yale University School of Medicine, New Haven, CT, USA.

Purpose Of Review: Prevalence of chronic low back pain (cLBP) is increasing. Sacroiliac joint (SIJ) is a common source of cLBP, but data behind its diagnosis and treatment is controversial. There is moderate quality evidence for effectiveness of therapeutic SIJ injections. Read More

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Intralesional corticosteroid injections are less painful without local anesthetic: a double-blind, randomized controlled trial.

J Dermatolog Treat 2021 Apr 7:1-4. Epub 2021 Apr 7.

Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Background: Corticosteroid injections are a commonly used treatment for dermatologic pathologies. Although the injectable is often prepared with a local anesthetic, we hypothesize that patients receiving an injection with anesthetic will experience no decrease in pain at the time of injection.

Methods: Patients requiring a corticosteroid injection were prospectively randomized into two cohorts to receive a corticosteroid (triamcinolone acetonide) combined with either lidocaine with epinephrine 1:100 000 (anesthetic) or bacteriostatic normal saline. Read More

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Strontium-90 brachytherapy following intralesional triamcinolone and 5-fluorouracil injections for keloid treatment: A randomized controlled trial.

PLoS One 2021 23;16(3):e0248799. Epub 2021 Mar 23.

Department of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.

Background: Keloid disease is hard to fully eradicate. Recurrence and other unsatisfactory results were found in many patients. No current therapeutic modality has been determined to be most effective for treating keloid scars. Read More

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Nail Psoriasis in Older Adults: Intralesional, Systemic, and Biological Therapy.

Dermatol Clin 2021 Apr 10;39(2):195-210. Epub 2021 Feb 10.

Department of Dermatology, Weill Cornell Medicine, New York, NY, USA. Electronic address:

Psoriasis may affect the skin, scalp, joints, and nails and is common in older adults. Intramatrical injections with triamcinolone acetonide are safe and effective in older individuals. Conventional systemic medications are relatively effective, but side effects, including laboratory abnormalities and drug interactions, are particularly common among older adults. Read More

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Response to treatment with intra-articular triamcinolone hexacetonide and triamcinolone acetonide in oligo articular juvenile idiopathic arthritis.

Pediatr Rheumatol Online J 2021 Mar 20;19(1):36. Epub 2021 Mar 20.

Department of Pediatric Rheumatology, University at Buffalo, Oishei Children's Hospital, Buffalo, NY, USA.

Background: Oligo-articular juvenile idiopathic arthritis (Oligo JIA) is the most common subtype of juvenile idiopathic arthritis. Intra-articular corticosteroid (IAC) injection is a mainstay treatment of oligo JIA providing pain relief, improving mobility and preventing further joint destruction in the majority of patients. In 2015, production of triamcinolone hexacetonide (TH) an intra-articular corticosteroid was discontinued in the United States leading to use of triamcinolone acetonide (TA) as an alternative. Read More

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Decreased recurrence of symptoms in oral lichen planus with intralesional injection of hyaluronic acid and triamcinolone.

Int J Oral Maxillofac Surg 2021 Mar 16. Epub 2021 Mar 16.

Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences and Department of Oral Medicine, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Oral lichen planus (OLP) is a chronic non-infectious, inflammatory, immunological disease. In contrast to skin lesions, which are often self-limiting, oral lesions rarely heal on their own and can be resistant to local and systemic treatments. In this clinical trial, hyaluronic acid (HA) was mixed with triamcinolone for intralesional injection to reduce side effects in the treatment of OLP. Read More

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The SPIKES protocol does not influence the tolerance or effectiveness of intra-articular corticosteroid injection in the knees of osteoarthritis patients: A prospective, controlled, randomized single-blinded trial.

Knee 2021 Mar 16;29:432-440. Epub 2021 Mar 16.

Division of Rheumatology, Universidade Federal de São Paulo - Escola Paulista de Medicina (UNIFESP - EPM), São Paulo, Brazil. Electronic address:

Background: Patient user embracement involves behaviours of including and listening to the patient, appreciating their complaints, and identifying their needs, whether individual or collective. The aim of this study was to evaluate the influence of a user embracement protocol (SPIKES protocol) for patients with knee osteoarthritis (OA) immediately before intra-articular injection (IAI) relative to procedure tolerance and its effectiveness in the immediate, short and medium terms.

Methods: This was a randomized controlled trial. Read More

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Long-term remission of unusual plasmoacanthoma on the nasal canthus achieved by intralesional corticosteroid injection: Insights into the pathogenesis and treatment planning based on a literature review.

J Dermatol 2021 Mar 19. Epub 2021 Mar 19.

Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan.

Plasmoacanthoma (PA) is a verrucous tumor predominantly developing on periorificial areas, which has been considered as an unusual subtype of plasmacytosis circumorificialis. Because of its rarity and clinical resemblance to several verrucous dermatological disorders, accurate diagnosis of PA is quite challenging. Herein, we present an extremely unusual case of PA which arose on both sides of the nasal canthus and was successfully treated with intralesional corticosteroid injections. Read More

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Topical oro-dispersible budesonide tablets for stricture prevention after near circumferential ESD for esophageal squamous cell cancer - a case report.

Z Gastroenterol 2021 Mar 18. Epub 2021 Mar 18.

Department of Medicine and Gastroenterology, Academic Teaching Hospital, University of Bonn, Bonn, Germany.

Background:  Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70-80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local injections and/or systemic steroids are given for prevention. Read More

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Difference in the efficacy of intravitreal dexamethasone implant before and after silicone oil removal: A case report.

Medicine (Baltimore) 2021 Mar;100(11):e25161

Department of Ophthalmology, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.

Rationale: An intravitreal dexamethasone (IV-DEX) implant is safe and effective for the treatment of macular edemas; however, the efficacy of IV-DEX implants in silicone oil (SO)-filled eyes remains controversial. There is no previous study comparing an IV-DEX implant in the same eye with and without intravitreal SO.

Patient Concerns: A 72-year-old man with proliferative diabetic retinopathy, macular edema, and rhegmatogenous retinal detachment, treated with pars plana vitrectomy with SO tamponade had refractory macular edema. Read More

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Safer local injection of triamcinolone acetonide for preventing post-endoscopic submucosal dissection esophageal stenosis.

Dig Endosc 2021 Mar 15. Epub 2021 Mar 15.

Department of Digestive Endoscopy, Tokyo Women's Medical University Hospital, Tokyo, Japan.

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Fluocinolone Acetonide 0.19 mg Implant in Patients with Cystoid Macular Edema Due To Irvine-Gass Syndrome.

Int Med Case Rep J 2021 26;14:127-132. Epub 2021 Feb 26.

Serviço de Oftalmologia, Centro Hospitalar e Universitário do Porto, Porto, Portugal.

Background: Cystoid macular edema (CME) due to Irvine-Gass syndrome (IGS) is one of the common causes of painless visual impairment post-cataract extraction. The treatment of recurrent cases remains unstandardized.

Objective: To evaluate the effectiveness and safety of fluocinolone acetonide intravitreal implant (0. Read More

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February 2021