138 results match your criteria infection-related terms

O-JMeSH: creating a bilingual English-Japanese controlled vocabulary of MeSH UIDs through machine translation and mutual information.

Genomics Inform 2021 Sep 30;19(3):e26. Epub 2021 Sep 30.

Graduate School of Integrative Science and Engineering, Tokyo City University, Tokyo 158-8557, Japan.

Previous approaches to create a controlled vocabulary for Japanese have resorted to existing bilingual dictionary and transformation rules to allow such mappings. However, given the possible new terms introduced due to coronavirus disease 2019 (COVID-19) and the emphasis on respiratory and infection-related terms, coverage might not be guaranteed. We propose creating a Japanese bilingual controlled vocabulary based on MeSH terms assigned to COVID-19 related publications in this work. Read More

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September 2021

Neuraxial anesthesia in a parturient with common variable immunodeficiency: a case report.

Int J Obstet Anesth 2021 Sep 16:103219. Epub 2021 Sep 16.

Department of Anesthesiology and Reanimation, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.

Choosing whether or not to initiate neuraxial anesthesia in pregnant women with immune system defects may be challenging. Anesthesiologists have the responsibility of making the best decision in terms of anesthesia management for both mother and baby during the labor and delivery process. Whether neuraxial anesthesia is associated with an increased risk of central nervous system infection in immunocompromised compared with healthy patients is unknown. Read More

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September 2021

Postoperative Analgesia after Open Liver Surgery: Systematic Review of Clinical Evidence.

J Clin Med 2021 Aug 18;10(16). Epub 2021 Aug 18.

Department of Anesthesiology and Critical Care, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.

Background: The existing recommendations for after open liver surgery, published in 2019, contains limited evidence on the use of regional analgesia techniques. The aim of this systematic review is to summarize available clinical evidence, published after September 2013, on systemic or blended postoperative analgesia for the prevention or treatment of postoperative pain after open liver surgery.

Methods: The PUBMED and EMBASE registries were used for the literature search to identify suitable studies. Read More

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Exploring prevalence of wound infections and related patient characteristics in homecare using natural language processing.

Int Wound J 2021 Jun 9. Epub 2021 Jun 9.

School of Nursing, Columbia University, New York City, New York, USA.

We aimed to create and validate a natural language processing algorithm to extract wound infection-related information from nursing notes. We also estimated wound infection prevalence in homecare settings and described related patient characteristics. In this retrospective cohort study, a natural language processing algorithm was developed and validated against a gold standard testing set. Read More

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Acquired Rectourethral and Rectovaginal Fistulas in Children: A Systematic Review.

Front Pediatr 2021 7;9:657251. Epub 2021 May 7.

Department of Biomedical Engineering, The Fourth Military Medical University, Xi'an, China.

Acquired rectourethral (RUF) or rectovaginal fistulas (RVF) in children are rare conditions in pediatric surgery. Prior literature are retrospective studies and based on a small number of patients. The managements and outcomes vary widely across different studies. Read More

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Differentially Expressed Gene Patterns in Ascarid-Infected Chickens of Higher- or Lower-Performing Genotypes.

Animals (Basel) 2021 Apr 2;11(4). Epub 2021 Apr 2.

Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology, 18196 Dummerstorf, Germany.

Here, we describe the first transcriptomic investigation of the peripheral blood of chickens exposed to and infections. We investigated differentially expressed gene (DEG) patterns in two chicken genotypes with either a higher (Lohmann Brown Plus, LB) or lower (Lohmann Dual, LD) laying performance level. The hens were experimentally coinfected with and , and their worm burdens and infection parameters were determined six weeks post infection. Read More

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Exploring the Trade-Off Between Economic and Health Outcomes During a Pandemic: A Discrete Choice Experiment of Lockdown Policies in Australia.

Patient 2021 05 11;14(3):359-371. Epub 2021 Mar 11.

Centre for Health Economics Research and Evaluation, University of Technology Sydney, PO Box 123, Broadway, Sydney, NSW, 2007, Australia.

Background: All countries experienced social and economic disruption and threats to health security from the COVID-19 pandemic in 2020, but the responses in terms of control measures varied considerably. While control measures, such as quarantine, lockdown and social distancing, reduce infections and infection-related deaths, they have severe negative economic and social consequences.

Objectives: The objective of this study was to explore the acceptability of different infectious disease control measures, and examine how respondents trade off between economic and health outcomes. Read More

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Infections developing in patients undergoing liver transplantation: Recipients of living donors may be more prone to bacterial/fungal infections.

Turk J Gastroenterol 2020 12;31(12):894-901

Department of Gastroenterology, Ege University School of Medicine, Bornova, Izmir, Turkey.

Background/aims: Despite surgical advances in liver transplantation and effective prophylactic strategies, posttransplant infections are the most important cause of morbidity and mortality. Diagnosis and management of infections because of developing immunosuppression is difficult and adversely affects mortality. This study aimed to review bacterial and fungal infections in patients after liver transplantation and to reveal the resistance rates. Read More

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December 2020

Clinical Outcome of Two-Stage Revision after Periprosthetic Shoulder Infection.

J Clin Med 2021 Jan 9;10(2). Epub 2021 Jan 9.

Department of Orthopaedics and Tumororthopaedics, University Hospital Muenster, 48149 Münster, Germany.

Background: Periprosthetic shoulder infections are devastating complications after shoulder arthroplasty. A potential treatment concept is a two-stage prosthesis exchange. Data are sparse in terms of clinical outcome, including infection-free survival and patient satisfaction after this procedure. Read More

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January 2021

Identifying Urinary Tract Infection-Related Information in Home Care Nursing Notes.

J Am Med Dir Assoc 2021 05 9;22(5):1015-1021.e2. Epub 2021 Jan 9.

Center for Home Care Policy & Research, Visiting Nurse Service of New York, New York, NY, USA; School of Nursing, Columbia University, New York, NY, USA; Data Science Institute, Columbia University, New York, NY, USA.

Objectives: Urinary tract infection (UTI) is common in home care but not easily captured with standard assessment. This study aimed to examine the value of nursing notes in detecting UTI signs and symptoms in home care.

Design: The study developed a natural language processing (NLP) algorithm to automatically identify UTI-related information in nursing notes. Read More

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[A prospective multi-center clinical investigation of HIV-negative pulmonary cryptococcosis in China].

Zhonghua Jie He He Hu Xi Za Zhi 2021 Jan;44(1):14-27

Department of Pulmonary and Critical Care Medicine, Guzhou Provincial People's Hospital,Guiyang 550002, China.

To investigate the current status of the diagnosis and treatment of pulmonary cryptococcosis in respiratory medicine and improve the understanding of the clinical characteristics of HIV-negative pulmonary cryptococcosis in China. A prospective multi-center open cohort study was designed to screen for pulmonary cryptococcosis in the general wards and intensive care units of the Department of Respiratory Diseases in 22 hospitals. The HIV-negative patients with positive cryptococcal etiological diagnosis based on smear culture, antigen detection and histopathology were enrolled in the study. Read More

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January 2021

Impact of COVID-19 on pediatric emergencies and hospitalizations in Singapore.

BMC Pediatr 2020 12 23;20(1):562. Epub 2020 Dec 23.

Duke-NUS Medical School, Singapore, Singapore.

Background: Coronavirus disease 2019 (COVID-19) has impacted the provision of health services in all specialties. We aim to study the impact of COVID-19 on the utilization of pediatric hospital services including emergency department (ED) attendances, hospitalizations, diagnostic categories and resource utilization in Singapore.

Methods: We performed a retrospective review of ED attendances and hospital admissions among children < 18 years old from January 1st to August 8th 2020 in a major pediatric hospital in Singapore. Read More

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December 2020

[Effect of breastfeeding on the development of infection-related diseases during hospitalization in late preterm infants in 25 hospitals in Beijing, China].

Zhongguo Dang Dai Er Ke Za Zhi 2020 Dec;22(12):1245-1250

Department of Pediatrics, First Hospital of Tsinghua University, Beijing 100016, China.

Objective: To investigate the incidence rate of infectious diseases during hospitalization in late preterm infants in Beijing, China, as well as the risk factors for infectious diseases and the effect of breastfeeding on the development of infectious diseases.

Methods: Related data were collected from the late preterm infants who were hospitalized in the neonatal wards of 25 hospitals in Beijing, China, from October 23, 2015 to October 30, 2017. According to the feeding pattern, they were divided into a breastfeeding group and a formula feeding group. Read More

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December 2020

pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression.

Expert Rev Clin Pharmacol 2021 Jan 15;14(1):55-66. Epub 2020 Dec 15.

Service De Néphrologie, Hémodialyse, Aphérèses Et Transplantation Rénale, CHU Grenoble-Alpes , Grenoble, France.

Introduction: Preexisting diabetes (PD) and post-transplant diabetes mellitus (PTDM) are common and severe comorbidities posttransplantation. The immunosuppressive regimens are modifiable risk factors.

Areas Covered: We reviewed Pubmed and Cochrane database and we summarize the mechanisms and impacts of available immunosuppressive treatments on the risk of PD and PTDM. Read More

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January 2021

Hypernatremia and moderate-to-severe hyponatremia are independent predictors of mortality in septic patients at emergency department presentation: A sub-group analysis of the need-speed trial.

Eur J Intern Med 2021 Jan 5;83:21-27. Epub 2020 Nov 5.

Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Emergency Medicine Department AOU Maggiore della Carità, Novara, Italy.

Study Objective: Early risk stratification of septic patients presenting to the emergency department (ED) is challenging. The aim of the study was to evaluate the prognostic role of plasmatic sodium level (Na) derangements at ED presentation in septic patients.

Methods: According to Na at ED presentation patients were divided in eunatremic (136-145 mEq/L), hypernatremic (>145 mEq/L) and hyponatremic (<136 mEq/L). Read More

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January 2021

The off-label use of anakinra in pediatric systemic autoinflammatory diseases.

Ther Adv Musculoskelet Dis 2020 16;12:1759720X20959575. Epub 2020 Oct 16.

Rheumatology Unit, Meyer Children's University Hospital, Viale Gaetano Pieraccini, 24, Firenze, Toscana 50139, Italy.

Interleukin 1 (IL-1), a central mediator of innate immunity, is considered a master cytokine of local and systemic inflammation. IL-1 has emerged as pivotal in the pathogenesis of autoinflammatory diseases (AIDs), and blockade of its pathway has become a crucial target for therapy. Anakinra (ANA), a recombinant IL-1β receptor antagonist, was the first anti-IL-1 agent employed in clinical practice. Read More

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October 2020

The survival analysis of tunnel-cuffed central venous catheter versus arteriovenous hemodialysis access among elderly patients: A retrospective single center study.

Ann Med Surg (Lond) 2020 Dec 21;60:76-80. Epub 2020 Oct 21.

Division of Nephrology, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand.

Background: There is currently a controversy for the optimal vascular access option in the elderly, regarding their multiple comorbidities and life expectancies. Our study aimed to compare the survival of tunneled cuff venous catheter (CVC) and arteriovenous access (AV access) in elderly patients.

Methods: A retrospective cohort study was performed by electronic medical record review. Read More

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December 2020

Structural Insights into the Interactions of Candidal Enolase with Human Vitronectin, Fibronectin and Plasminogen.

Int J Mol Sci 2020 Oct 22;21(21). Epub 2020 Oct 22.

Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Krakow, 30-387 Kraków, Poland.

Significant amounts of enolase-a cytosolic enzyme involved in the glycolysis pathway-are exposed on the cell surface of Candida yeast. It has been hypothesized that this exposed enolase form contributes to infection-related phenomena such as fungal adhesion to human tissues, and the activation of fibrinolysis and extracellular matrix degradation. The aim of the present study was to characterize, in structural terms, the protein-protein interactions underlying these moonlighting functions of enolase. Read More

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October 2020

Drug repurposing using computational methods to identify therapeutic options for COVID-19.

J Diabetes Metab Disord 2020 May 30:1-9. Epub 2020 May 30.

Department of Biotechnology, Biological Faculty, Alzahra University, Tehran, Iran.

Purpose: Recently, the world has been dealing with a new type of coronavirus called COVID-19 that in terms of symptoms is similar to the SARS coronavirus. Unfortunately, researchers could not find a registered therapy to treat the infection related to the virus yet. Regarding the fact that drug repurposing is a good strategy for epidemic viral infection, we applied the drug repurposing strategy using virtual screening to identify therapeutic options for COVID-19. Read More

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Effect of Salvage Chemotherapy Before Donor Lymphocyte Infusion in Patients With Relapse After Allogeneic Hematologic Stem Cell Transplantation.

Transplant Proc 2021 Jan-Feb;53(1):391-395. Epub 2020 Jul 11.

Faculty of Medicine, Department of Hematology, Hacettepe University, Ankara, Turkey.

Objectives: Allogeneic hematopoietic stem cell transplantation (AHSCT) is an important treatment option in hematologic malignancies. Relapse after AHSCT is an indicator of poor prognosis. These patients may be treated with donor lymphocyte infusion (DLI). Read More

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Spatial modeling, risk mapping, change detection, and outbreak trend analysis of coronavirus (COVID-19) in Iran (days between February 19 and June 14, 2020).

Int J Infect Dis 2020 Sep 20;98:90-108. Epub 2020 Jun 20.

Shiraz Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Objectives: Coronavirus disease 2019 (COVID-19) represents a major pandemic threat that has spread to more than 212 countries with more than 432,902 recorded deaths and 7,898,442 confirmed cases worldwide so far (on June 14, 2020). It is crucial to investigate the spatial drivers to prevent and control the epidemic of COVID-19.

Methods: This is the first comprehensive study of COVID-19 in Iran; and it carries out spatial modeling, risk mapping, change detection, and outbreak trend analysis of the disease spread. Read More

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September 2020

Fear of Hospital-Acquired Infections: The Combined Impact of Patient's Hygiene Sensitivity and Perceived Staff Preventive Behavior.

J Community Health 2020 12;45(6):1211-1219

Faculty of Business Administration, Ono Academic College, 104 Zahal Street, 55000, Kiryat Ono, Israel.

Over the years, the public has paid growing attention to hospital-acquired infections (HAIs). Currently, infection prevention and control are considered a number one national priority in leading developed countries. However, while some hospital visitors are knowledgeable of the topic, others may be ignorant or careless as regards sterility and hygiene-related matters. Read More

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December 2020

Single-Stage Reconstruction with Titanium Mesh for Compound Comminuted Depressed Skull Fracture.

Ki Seong Eom

J Korean Neurosurg Soc 2020 Sep 8;63(5):631-639. Epub 2020 May 8.

Department of Neurosurgery, Institute of Wonkwang Medical Science, Wonkwang University Hospital, Iksan, Korea.

Objective: Traditionally, staged surgery has been preferred in the treatment of compound comminuted depressed fracture (FCCD) after traumatic brain injury (TBI) and involves the removal of primarily damaged bone and subsequent cranioplasty. The main reason for delayed cranioplasty was to reduce the risk of infection-related complications. Here, the author performed immediate reconstruction using a titanium mesh in consecutive patients with FCCD after TBI, reported the surgical results, and reviewed previous studies. Read More

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September 2020

Fluoroquinolone Prophylaxis in Autologous Stem Cell Transplantation: Worthy of a Second Look.

Biol Blood Marrow Transplant 2020 08 15;26(8):e198-e201. Epub 2020 Apr 15.

Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.

Prophylaxis with fluoroquinolone (FQ) for patients undergoing autologous stem cell transplantation (ASCT) remains controversial. We performed a retrospective review of patients undergoing ASCT with and without bacterial prophylaxis to compare endpoints of interest. In accordance with institutional policy, patients undergoing ASCT for multiple myeloma routinely receive levofloxacin prophylaxis during their period of neutropenia, whereas patients undergoing the ASCT for lymphoma do not. Read More

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Respiratory tract infection-related healthcare utilisation in children with Down's syndrome.

Infection 2020 Jun 14;48(3):403-410. Epub 2020 Mar 14.

UCL Institute of Epidemiology and Healthcare, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.

Purpose: Children with Down's syndrome (DS) are prone to respiratory tract infections (RTIs) due to anatomical variation, immune system immaturity and comorbidities. However, evidence on RTI-related healthcare utilisation, especially in primary care, is incomplete. In this retrospective cohort study, we use routinely collected primary and secondary care data to quantify RTI-related healthcare utilisation in children with DS and matched controls without DS. Read More

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Recovery from infection is more likely to favour the evolution of migration than social escape from infection.

J Anim Ecol 2020 06 27;89(6):1448-1457. Epub 2020 Mar 27.

Département de sciences biologiques, Université de Montréal, Montréal, QC, Canada.

Pathogen and parasite infections are increasingly recognized as powerful drivers of animal movement, including migration. Yet, infection-related migration benefits can result from a combination of environmental and/or social conditions, which can be difficult to disentangle. Here, we focus on two infection-related mechanisms that can favour migration: moving to escape versus recover from infection. Read More

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Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol.

Trials 2019 Dec 19;20(1):754. Epub 2019 Dec 19.

Pharmacoepidemiology and Statistics Research Center (PESRC), Chiang Mai University, Chiang Mai, 50200, Thailand.

Background: Current international guidelines recommend the use of a daily topical exit-site antimicrobial to prevent peritoneal dialysis (PD)-related infections. Although nonantibiotic-based therapies are appealing because they may limit antimicrobial resistance, no controlled trials have been conducted to compare topical antimicrobial agents with usual exit-site care for the prevention of PD-related infections among the Thai PD population. We propose a controlled three-arm trial to examine the efficacy and safety of a daily chlorhexidine gluconate-impregnated patch versus mupirocin ointment versus usual exit-site care with normal saline for the prevention of PD-related infections. Read More

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December 2019

Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung.

BMC Genomics 2019 Dec 16;20(1):984. Epub 2019 Dec 16.

Department of Pharmacology, University of Illinois, Chicago, USA.

Background: Pseudomonas aeruginosa (PA) is an opportunistic Gram-negative bacterium that causes serious life threatening and nosocomial infections including pneumonia. PA has the ability to alter host genome to facilitate its invasion, thus increasing the virulence of the organism. Sphingosine-1- phosphate (S1P), a bioactive lipid, is known to play a key role in facilitating infection. Read More

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December 2019

Stillbirth Associated With Infection in a Diverse U.S. Cohort.

Obstet Gynecol 2019 12;134(6):1187-1196

University of Utah Health Sciences, Salt Lake City, and Intermountain Health Care, Murray, Utah; RTI International, Research Triangle Park, North Carolina; the University of Virginia Healthcare, Charlottesville, Virginia; the University of Texas Medical Branch at Galveston, Galveston, Texas; Columbia University, New York, New York; the University of Texas Health Science Center at Houston, Houston, Texas; Rollins School of Public Health, Emory University, Atlanta, Georgia; the University of Texas at Austin, Austin, and the University of Texas Health Science Center at San Antonio, San Antonio, Texas; and Yale School of Medicine, New Haven, Connecticut.

Objective: To better characterize infection-related stillbirth in terms of pathogenesis and microbiology.

Methods: We conducted a secondary analysis of 512 stillbirths in a prospective, multisite, geographically, racially and ethnically diverse, population-based study of stillbirth in the United States. Cases underwent evaluation that included maternal interview, chart abstraction, biospecimen collection, fetal autopsy, and placental pathology. Read More

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December 2019

IVF in Africa: what is it all about?

W Ombelet J Onofre

Facts Views Vis Obgyn 2019 Mar;11(1):65-76

Genk Institute for Fertility Technology, Department of Obstetrics and Gynaecology, Schiepse Bos 6, 3600 Genk, Belgium.

Infertility is a universal problem with the highest prevalence in low-resource countries, particularly in sub-Saharan Africa where infection-related tubal damage is the commonest cause. It is estimated that more than 180 million couples in developing countries suffer from primary or secondary infertility. In most African countries, the social stigma of childlessness still leads to isolation and abandonment. Read More

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