137,094 results match your criteria infants congenital


Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis.

PLoS One 2021 20;16(9):e0257584. Epub 2021 Sep 20.

Department of Pharmacy, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.

Background: Nausea and vomiting of pregnancy affects up to 80% of pregnant women, it typically occurs during the first trimester which is the most sensitive time for environmental exposures given organogenesis. Metoclopramide is an antiemetic drug used widely during NVP, but the findings of studies evaluating its safety of use in pregnancy is inconsistent. Therefore, we conducted a systematic review and meta-analysis to assess whether metoclopramide use during first trimester of pregnancy is associated with the risk of major congenital malformations. Read More

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September 2021

The epidemiology of respiratory syncytial virus: A retrospective review from Steve Biko Academic Hospital 2013 - 2016.

Afr J Thorac Crit Care Med 2018 3;24(1). Epub 2018 Apr 3.

Department of Paediatrics and Child Health, Faculty of Health Sciences, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.

Background: Respiratory syncytial virus (RSV) bronchiolitis is a seasonal disease that has an enormous burden on health systems across the world. RSV disease manifestations in children range from mild upper respiratory tract infections to severe lower respiratory tract infections, including pneumonia and bronchiolitis. In South Africa, the seasonality of RSV disease causing both upper and lower respiratory tract illness is well documented. Read More

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Thoracoabdominal duplication with hematochezia as an onset symptom in a baby: A case report.

World J Clin Cases 2021 Aug;9(24):7261-7268

Department of Surgery, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China.

Background: Alimentary tract duplication is a rare congenital disease that may occur in any part of the alimentary tract, whereas thoracoabdominal duplications only account for approximately 2% of all alimentary tract duplication cases. Many symptoms, including abdominal pain, abdominal distension, vomiting, gastrointestinal bleeding, chest discomfort, chest pain, and shortness of breath, may be present in patients with abdominal or thoracic duplication.

Case Summary: A 10-mo-old infant, with a free previous medical history, was admitted to our hospital with melena three times in 6 d. Read More

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Epidemiology, Genetics and Epigenetics of Congenital Heart Diseases in Twins.

Cureus 2021 Aug 17;13(8):e17253. Epub 2021 Aug 17.

Otolaryngology, Dayanand Medical College Ludhiana, Punjab, IND.

Congenital heart defects (CHDs) refer to abnormalities in the heart function that arise at the fetal stages. It is the most common birth defect that affects 0.8% of all liveborn infants. Read More

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MIS-C with diarrhea complaint and acute kidney injury: A pediatric COVID-19 patient.

Prog Pediatr Cardiol 2021 Sep 15:101436. Epub 2021 Sep 15.

Kahramanmaras Sutcu Imam University Medical Faculty, Department of Radiology, Kahramanmaras, Turkey.

We present the case of a 3-month-old male infant patient who initially presented with severe dehydration with acute kidney injury secondary to COVID-19. Regarding the individual's previous history, the patient had congenital heart disease and was taking furosemide and captopril. The patient improved after initial hydration therapy. Read More

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September 2021

An infant with suspected missed diagnosis of Williams syndrome failed weaning off CPB after surgical correction of pulmonary stenosis: a case report and literature review.

Perfusion 2021 Sep 18:2676591211046876. Epub 2021 Sep 18.

Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, P.R. China.

Williams syndrome (WS) is a rare congenital developmental disorder caused by the deletion of between 26 and 28 genes on chromosome 7q11.23. For patients with WS, in view of the particularity of the supravalvular aortic stenosis, choosing appropriate arterial cannula, maintaining higher perfusion pressure as well as strengthening myocardial protection during cardiopulmonary bypass (CPB) is essential to the clinical outcome. Read More

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September 2021

Early Identification and Management of Congenital Cytomegalovirus.

Otolaryngol Clin North Am 2021 Sep 15. Epub 2021 Sep 15.

Department Otolaryngology-Head & Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Division of Otolaryngology-Head & Neck Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Chicago, IL 60611, USA. Electronic address:

Congenital cytomegalovirus (cCMV) is the most common nongenetic cause of sensorineural hearing loss. Despite its prevalence, universal screening for cCMV is not currently performed. Hearing loss caused by cCMV is most often severe to profound, often bilateral, and may be fluctuating or progressive. Read More

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September 2021

Early skin contact combined with mother's breastfeeding to shorten the process of premature infants ≤ 30 weeks of gestation to achieve full oral feeding: the study protocol of a randomized controlled trial.

Trials 2021 Sep 17;22(1):637. Epub 2021 Sep 17.

Children's Hospital of Fudan University, 399 Wan Yuan Road, Shanghai, 201102, China.

Background: Most hospitalized preterm infants experience difficulties in transitioning from tube feeding to full oral feeding. Interventions to promote full oral feeding in preterm infants in the neonatal intensive care unit (NICU) are limited to pacifier use or bottle-feeding exercises. Skin contact has been shown to be beneficial to start and maintain lactation and provide preterm infants with the opportunity to suck on the mother's breast, which may promote further development of the preterm infant's suckling patterns. Read More

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September 2021

Dental Management of Congenital Granular Cell Lesion and Neonatal Teeth: A Case Report.

J Clin Pediatr Dent 2021 Oct;45(4):269-272

Congenital granular cell lesion (CGCL) is a rare benign oral cavity tumor in infants. Neonatal teeth are also rare dental anomalies that appear during the first month of life. This report describes a case of eruption of neonatal teeth after surgical excision of CGCL. Read More

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October 2021

Universal newborn hearing screening in the Italian Region of Sicily in 2018.

Acta Otorhinolaryngol Ital 2021 Aug;41(4):356-363

Neurosensorial Disability Research, INAPP/ Italian Institute of Social Medicine, Rome, Italy.

Objectives: We have clarified the role of Universal Neonatal Hearing Screening (UNHS) for both early diagnosis and rapid treatment in order to improve the prognosis of the deaf child and reduce patient management costs. Although in Sicily UNHS has been progressively implemented, there is scarce data in the literature on this matter. Therefore, the main objective was to collect in the year 2018 the following data: number of newborns screened for hearing loss, number of infants "referred" to transiently evoked otoacoustic emissions (TEOAE), number of infants with pathologic auditory brainstem response (ABR) and number of infants affected by permanent hearing loss. Read More

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Ultrasound of congenital spine anomalies.

Pediatr Radiol 2021 Sep 16. Epub 2021 Sep 16.

Department of Radiology, Nationwide Children's Hospital,, ED Building, 4th Floor, 700 Children's Drive, Columbus, OH, 43205, USA.

Ultrasonography (US) is the first-line imaging modality for screening neonates and young infants with suspected spinal abnormalities. Whether performed for a suspicious congenital skin lesion, such as a lumbosacral tract or lipomatous mass, or abnormal neurological findings, US can help define spinal anatomy, characterize congenital spine malformations, and direct further work-up and management. The purpose of this article is to review the diagnostic imaging approach to infant spine US, including technique and indications, normal anatomy and variants with a focus on embryological origins, and classification and diagnosis of congenital spine malformations. Read More

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September 2021

Newborn Pulse Oximetry for Infants Born Out-of-Hospital.

Pediatrics 2021 Sep 16. Epub 2021 Sep 16.

Cardiology Care for Children, Lancaster, Pennsylvania

Background And Objectives: Conventional timing of newborn pulse oximetry screening is not ideal for infants born out-of-hospital. We implemented a newborn pulse oximetry screen to align with typical midwifery care and measure its efficacy at detecting critical congenital heart disease.

Methods: Cohort study of expectant mothers and infants mainly from the Amish and Mennonite (Plain) communities with limited prenatal ultrasound use. Read More

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September 2021

Balloon dilation and rapid maxillary expansion: a novel combination treatment for congenital nasal pyriform aperture stenosis in an infant.

Ital J Pediatr 2021 Sep 16;47(1):189. Epub 2021 Sep 16.

Unit of Dentistry, Bambino Gesù Children's Hospital, 00165, Rome, Italy.

Background: Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition that may occur alone or as part of a multi-formative syndrome. Management remains difficult. There is no specific treatment protocol. Read More

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September 2021

Frontonasal glioma - diagnostic difficulties.

Med Pharm Rep 2021 Aug 10;94(Suppl No 1):S33-S35. Epub 2021 Aug 10.

Clinical Hospital, Cluj-Napoca, Romania.

Nasal glioma or nasal glial heterotopia represents a rare rare benign tumor of the median line. Prenatal and even postnatal imagingc diagnosis of congenital frontonasal masses is difficult. We describe the case of an infant presenting with a lateral nasal mass. Read More

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Enzymatic Changes in Red Blood Cells of Diamond-Blackfan Anemia.

Tohoku J Exp Med 2021 ;255(1):49-55

Department of Transfusion Medicine and Cell Processing, Faculty of Medicine, Tokyo Women's Medical University.

Diamond-Blackfan anemia is a congenital bone marrow failure syndrome characterized by red blood cell (RBC) aplasia with varied malformations in infants. Elevated activity of adenosine deaminase (ADA) has been considered as a useful biomarker of Diamond-Blackfan anemia, and ADA assay has been shown to be more sensitive than genetic diagnosis. Approximately, 80% of the examined patients showed elevated ADA activity, whereas genetic tests of ribosome subunit genes identified mutations in approximately 60% of the patients. Read More

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January 2021

and variants in neonatal-onset versus infantile-onset primary congenital glaucoma.

Br J Ophthalmol 2021 Sep 15. Epub 2021 Sep 15.

Advanced Eye Center, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Objective: To compare and variants in a cohort of neonatal-onset (NO) and infantile-onset (IO) primary congenital glaucoma (PCG).

Methods: This prospective observational study included 43 infants with PCG (14 NO and 29 IO) presenting between January 2017 and January 2019 with a minimum 1-year follow-up. and genes were screened using Sanger sequencing with in-silico analysis of the variants using Polymorphism Phenotyping v. Read More

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September 2021

Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly.

PLoS One 2021 15;16(9):e0256444. Epub 2021 Sep 15.

Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, BA, Brazil.

Objective: To describe the neurological and neurodevelopmental outcomes of children with Congenital Zika Syndrome (CZS) associated microcephaly beyond 2 years of age.

Method: We followed children with CZS-associated microcephaly in an outpatient clinic in Salvador, Brazil. Neurological and neurodevelopmental assessments were performed using the Hammersmith Infant Neurological Examination (HINE) and Bayley Scales of Infant and Toddler Neurodevelopment (Bayley-III) respectively. Read More

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September 2021

TeleNICU: Extending the reach of level IV care and optimizing the triage of patient transfers.

J Telemed Telecare 2021 Sep 15:1357633X211038153. Epub 2021 Sep 15.

12334The University of Texas Southwestern Medical Center, USA.

Background: The use of telemedicine to provide care for critically ill newborn infants has significantly evolved over the last two decades. Children's Health System of Texas and University of Texas Southwestern Medical Center established TeleNICU, the first teleneonatology program in Texas.

Objective: To evaluate the effectiveness of Tele Neonatal Intensive Care Unit (TeleNICU) in extending quaternary neonatal care to more rural areas of Texas. Read More

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September 2021

Evaluation of Clinical Course and Maintenance Drug Treatment of Supraventricular Tachycardia in Children During the First Years of Life. A Cohort Study from Eastern Germany.

Pediatr Cardiol 2021 Sep 15. Epub 2021 Sep 15.

Department for Pediatric Cardiology, University of Leipzig-Heart Center, Strümpellstr. 39, 04289, Leipzig, Germany.

Supraventricular tachycardia (SVT) is considered the most common cause of arrhythmia in children and infants. Regarding the likelihood of a spontaneous resolution of SVTs during the first years of life, drug treatment aims to bridge the time until children 'grow out' out of the arrhythmia. The choice of antiarrhythmic agents and the planning of maintenance therapy are mainly based on clinical experience and retrospective single- and multi-institutional analyses and databases from all over the world approaching differently to this topic. Read More

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September 2021

Assessing Loss to Follow-up After Newborn Hearing Screening in the Neonatal Intensive Care Unit: Sociodemographic Factors That Affect Completion of Initial Audiological Evaluation.

Ear Hear 2021 Sep 14. Epub 2021 Sep 14.

Boston University School of Medicine, Boston, Massachusetts, USA Department of Otolaryngology-Head and Neck Surgery, Boston Medical Center, Boston, Massachusetts, USA.

Objectives: Neonatal intensive care unit (NICU) patients are at high risk for congenital hearing loss. Previous studies have found sociodemographic factors associated with loss to follow-up for newborn hearing screening, but none have specifically studied the NICU population. Our objective is to determine if demographics and socioeconomic status is associated with loss to follow-up in a newborn population with extended NICU stay. Read More

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September 2021

Microsurgical and Endovascular Management of Congenital Iliac Aneurysms in the Neonatal Period: Two Cases and a Literature Review.

EJVES Vasc Forum 2021 21;52:41-48. Epub 2021 Jun 21.

Department of Surgery, Division of Paediatric Surgery, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada.

Introduction: Congenital aneurysms of major arteries are very rare diagnoses and prognosis can be poor if treatment is not initiated rapidly. This is the presentation of two cases of infants with congenital iliac aneurysms who underwent treatment in the neonatal period. The report then proceeds with a literature review of paediatric iliac aneurysms. Read More

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Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study.

Sultan Qaboos Univ Med J 2021 Aug 29;21(3):457-464. Epub 2021 Aug 29.

Department of Pediatric Intensive Care, Royal Hospital, Muscat, Oman.

Objectives: A modified Blalock-Taussig (mBT) shunt procedure is a common palliative surgery used to treat infants and children with cyanotic congenital heart disease (CCHD). This study aimed to report the outcomes of infants and children undergoing mBT shunt procedures in Oman. In addition, risk factors associated with early mortality, inter-stage mortality and reintervention were assessed. Read More

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Frequency of Cardiac Arrhythmias in Children with Cardiological Consulting and Containing Electrocardiogram.

Cardiovasc Hematol Disord Drug Targets 2021 Sep 13. Epub 2021 Sep 13.

Student of Research Committee, Lorestan University of Medical Sciences, Khorramabad. Iran.

Background: Heart diseases are the leading causes of mortality and congenital heart disease (CHD) is the most common birth defect reported worldwide.

Objective: The aim of this study was to evaluate the incidence of arrhythmias and CHD and the association between the two, among infants and children reported to our center.

Methods: This cross-sectional study included infants and children who were referred to Shahid Madani Hospital, Khorramabad. Read More

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September 2021

Viridans Group Streptococcus Meningitis in an Immunocompetent Child: A Case Report.

Am J Case Rep 2021 Sep 14;22:e933089. Epub 2021 Sep 14.

Department of Pediatrics, Umm Al Qura University, Mecca, Saudi Arabia.

BACKGROUND Viridans group streptococci (VGS) are commensal organisms in humans that are considered contaminants when isolated from culture specimens. However, VGS can be pathogenic when recovered multiple times from blood cultures or when in immunocompromised hosts. VGS are the leading cause of dental abscesses and infective endocarditis in children with underlying congenital heart diseases. Read More

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September 2021

Congenital Cytomegalovirus Targeted Screening Implementation and Outcomes: A Retrospective Chart Review.

Otolaryngol Head Neck Surg 2021 Sep 14:1945998211044125. Epub 2021 Sep 14.

Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear and Harvard Medical School, Boston, Massachusetts, USA.

Objective: To assess the effectiveness and outcomes of a targeted cytomegalovirus (CMV) testing protocol.

Study Design: Retrospective chart review.

Setting: Tertiary care institution. Read More

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September 2021

Feasibility and acceptability of targeted salivary cytomegalovirus screening through universal newborn hearing screening.

J Paediatr Child Health 2021 Sep 14. Epub 2021 Sep 14.

Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.

Aim: This study aimed to determine the feasibility and parental acceptability of screening for congenital cytomegalovirus (cCMV) through saliva polymerase chain reaction in infants who did not pass their newborn hearing screening. Additionally, the utility (i.e. Read More

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September 2021

Screening and Detection of Congenital Hypothyroidism in Newborns.

Neonatal Netw 2021 Aug;40(5):335-339

Unrecognized congenital hypothyroidism (CH) is the most common cause of preventable cognitive delay in children. Infants with CH appear normal and are usually asymptomatic at birth. Early detection is critical for prevention of intellectual disability. Read More

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A Broken Pathway: Understanding Congenital Adrenal Hyperplasia in the Newborn.

Authors:
Kelly Allis

Neonatal Netw 2021 Aug;40(5):286-294

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder that leads to the partial or complete deficiency of cortisol and aldosterone production from the adrenal glands. The lack of these key hormones can precipitate acute adrenal crisis during the newborn period. This disorder can further lead to the development of virilized female genitalia from exposure to increased levels of androgens during fetal development. Read More

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Prenatal Motivation for Caregiving Issues: A Pilot Study of Mothers Expecting Healthy Infants and Infants With Complex Congenital Heart Disease.

Res Theory Nurs Pract 2021 Sep 13. Epub 2021 Sep 13.

School of Nursing, University of Wisconsin-Madison, Wisconsin.

Background And Purpose: The prenatal preparing women do for infant caregiving is understudied. In this pilot, multimethods study, we examined motivation for preparing for infant caregiving of women in their third trimester of pregnancy expecting either a healthy infant or an infant with complex congenital heart disease (CCHD).

Methods: Eleven women expecting a healthy infant and four expecting an infant with CCHD completed a questionnaire and were interviewed. Read More

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September 2021