Cell Mol Gastroenterol Hepatol 2021 Jun 29;12(4):1251-1266. Epub 2021 Jun 29.
BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada; Division of Gastroenterology, Hepatology and Nutrition, BC Children's Hospital, Vancouver, Canada. Electronic address:
Background & Aims: Exclusive enteral nutrition (EEN) is used to treat pediatric Crohn's disease (CD), but therapeutic benefits are variable, and EEN can lead to microbial dysbiosis. Because of reported lower efficacy EEN is not routinely used to treat pediatric ulcerative colitis (UC). Inulin-type fructans (IN) beneficially modulate the gut microbiome and promote expansion of anti-inflammatory immune cells. Read More