Molecules 2020 Dec 11;25(24). Epub 2020 Dec 11.
Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanamapatti, Tamilnadu 621007, India.
In this study, the synthesis of one-pot 10-phenyl-3,4,6,7-tetrahydro-1-spiro [acridine-9,2'-indoline]-1,3,8-trione derivatives was achieved via a four-component cyclocondensation reaction, which was carried out in solvent-free conditions, and using p-toluenesulfonic acid (p-TSA) as a catalyst. The product was confirmed by FT-IR, H-NMR, C-NMR, mass spectra, and elemental analysis. Furthermore, the anticancer activity was screened for all compounds. Read More