Neuroimage 2021 Oct 11:118640. Epub 2021 Oct 11.
Department of Psychology, University of Roehampton, Grove House, Roehampton Lane, London, SW15 5PJ, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, De Crespigny Park, London, SE5 8AF, UK; Department of Psychiatry, Icahn Medical Institute, Mount Sinai Hospital, 1 Gustave L. Levy Place, Box 1230, New York, NY 10029, USA.
Neuroimaging studies have found 'reality monitoring', our ability to distinguish internally generated experiences from those derived from the external world, to be associated with activity in the medial prefrontal cortex (mPFC) of the brain. Here we probe the functional underpinning of this ability using real-time fMRI neurofeedback to investigate the involvement of mPFC in recollection of the source of self-generated information. Thirty-nine healthy individuals underwent neurofeedback training in a between groups study receiving either Active feedback derived from the paracingulate region of the mPFC (21 subjects) or Sham feedback based on a similar level of randomised signal (18 subjects). Read More