475 results match your criteria indicated nhl

"Wrap-Around Sign" in Non-Hodgkin Lymphoma of the Spine: A Common yet Overlooked Imaging Feature?

World Neurosurg 2021 Apr 22. Epub 2021 Apr 22.

Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905. Electronic address:

Background: Anecdotal cases of the so-called "wrap-around" appearance in non-Hodgkin lymphoma (NHL) of the spine exist in the medical literature. In this paper, we looked at the prevalence of this imaging feature in our institutional cases.

Materials And Methods: We screened our institutional database for biopsy proven NHL. Read More

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is a Novel Prognostic Marker for Diffuse Large B-Cell Lymphoma.

Pharmgenomics Pers Med 2021 1;14:397-408. Epub 2021 Apr 1.

Department of Hematology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.

Purpose: Diffuse large B-cell lymphoma (DLBCL) is the most common B-cell malignancy. Thirty to forty percent of DLBCL patients still experience relapse or develop refractory disease even with standard immunochemotherapy, leading to a poor prognosis. Currently, although several gene-based classification methods can be used to predict the prognosis of DLBCL, some patients are still unable to be classified. Read More

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Body Composition Change, Unhealthy Lifestyles and Steroid Treatment as Predictor of Metabolic Risk in Non-Hodgkin's Lymphoma Survivors.

J Pers Med 2021 Mar 17;11(3). Epub 2021 Mar 17.

Hematology Unit-IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.

Unhealthy lifestyle, as sedentary, unbalanced diet, smoking, and body composition change are often observed in non-Hodgkin's lymphoma (NHL) survivors, and could be determinant for the onset of cancer treatment-induced metabolic syndrome (CTIMetS), including abdominal obesity, sarcopenia, and insulin resistance. The aim of this study was to assess whether changes in body composition, unhealthy lifestyles and types of anti-cancer treatment could increase the risk of metabolic syndrome (MetSyn) and sarcopenia in long-term NHL survivors. We enrolled 60 consecutive NHL patients in continuous remission for at least 3 years. Read More

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The Secondary Manifestation of a Marginal Zone Lymphoma in the Larynx: Lessons From a Misdiagnosis.

Cureus 2021 Feb 18;13(2):e13410. Epub 2021 Feb 18.

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Mannheim, Mannheim, DEU.

The secondary manifestation of a marginal zone lymphoma (MZL), which is a less common type of B-cell non-Hodgkin's Lymphoma (NHL), in the larynx is a rarity. We report a case of the secondary involvement of the larynx following MZL in a 72-year-old woman who presented with the sensation of a foreign body in the throat and history of MZL. A fiberoptic laryngoscopy confirmed the presence of a mass in the supraglottic area. Read More

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February 2021

A randomized and comparative study to assess safety and efficacy of supplemental treatment of a herbal formulation - comprising essential oils in patients with corona virus 2019 (COVID-19).

Contemp Clin Trials Commun 2021 Jun 11;22:100755. Epub 2021 Mar 11.

M/s Accuprec Research Labs Pvt Ltd., Ahmedabad, 382213, Gujarat, India.

Objective: The purpose of this study was to examine the effect of herbal formulation - Aayudh Advance on viral load as well as recovery duration in mild symptomatic patients diagnosed with Corona Virus Disease 2019 (COVID-19). It also aimed to study the effect of Herbal formulation - Aayudh Advance in terms of clinical improvement of various sign and symptoms in mild symptomatic COVID-19 patients.

Method: Once the patient suffice the requirement of inclusion, exclusion criteria of the study than as per the method of 'Covariate Adaptive Randomization' technique, patient was assigned in either Aayudh Advance arm (Test arm) or Control Arm. Read More

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Epidemiological characterization of pityriasis versicolor and distribution of Malassezia species among students in Hai Phong city, Vietnam.

Curr Med Mycol 2020 Jun;6(2):37-42

nd Department of Pediatrics, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Background And Purpose: Invasive fungal infections (IFIs) are a major cause of morbidity and mortality in immunocompromised children. The purpose of our study was to evaluate the incidence of IFIs in pediatric patients with underlying hematologic malignancies and determine the patient characteristics, predisposing factors, diagnosis, treatment efficacy, and outcome of IFIs.

Materials And Methods: For the purpose of the study, a retrospective analysis was performed on cases with proven and probable fungal infections from January 2001 to December 2016 (16 years). Read More

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The effect of bulky mass on prognosis in diffuse large-B-cell lymphoma: still poor?

Leuk Res 2021 03 4;102:106521. Epub 2021 Feb 4.

Department of Hematology and Bone Marrow Transplantation Center, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

The introduction of rituximab to the CHOP protocol has demonstrated an improvement in PFS and OS in DLBCL patients with both early and advanced stages. Most studies in the pre-rituximab period indicated that bulky disease has an unfavorable impact on clinical outcomes of DLBCL. The effect of bulky mass on the outcome of DLBCL patients undergoing R-CHOP therapy remained uncertain. Read More

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Association between common variants in vitamin D receptor gene and susceptibility to Non-Hodgkin's lymphoma: a case-control study.

Nucleosides Nucleotides Nucleic Acids 2021 15;40(3):288-299. Epub 2021 Jan 15.

Genetic of Non-Communicable Disease Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Vitamin D VDR)-mediated signaling contributes to the cell signaling pathways that affect cancer development. This study is conducted on 104 patients diagnosed with non-Hodgkin's lymphoma (NHL) and 246 healthy subjects to investigate the link between five genetic variants spanning the VDR gene and the risk of this malignancy in Iranian subjects. The PCR-RFLP method was used for the analysis of (rs1544410), (rs7975232), (rs2228570) and (rs731236) variants. Read More

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January 2021

Validation and psychometric evaluation of the Dutch person-centred care of older people with cognitive impairment in acute care (POPAC) scale.

BMC Health Serv Res 2021 Jan 13;21(1):59. Epub 2021 Jan 13.

Health Sciences-Nursing Science & Education University of Groningen & University Medical Center Groningen, Hanzeplein 1, Postbox 30.001, 9700, RB, Groningen, The Netherlands.

Background: Person-centred care is the preferred model for caring for people with dementia. Knowledge of the level of person-centred care is essential for improving the quality of care for patients with dementia. The person-centred care of older people with cognitive impairment in acute care (POPAC) scale is a tool to determine the level of person-centred care. Read More

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January 2021

Rheumatologic manifestations of Hepatitis C Virus.

Minerva Med 2021 Apr 2;112(2):201-214. Epub 2020 Dec 2.

Department of Medicine, Rheumatology Clinic, University of Udine, ASUFC, Udine, Italy.

Introduction: Hepatitis C Virus (HCV) is a well-known worldwide infection, responsible for hepatic and extrahepatic complications. Among extrahepatic manifestation, the rheumatologic are the most common ones. With the arrival of Direct Antiviral Agents (DAA), the treatment and the clinical perspective have rapidly changed, permitting to achieve a sustained virological response (SVR) and preventing complications of chronic infection. Read More

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Quantifying the Effect of Financial Burden on Health-Related Quality of Life among Patients with Non-Hodgkin's Lymphomas.

Cancers (Basel) 2020 Nov 11;12(11). Epub 2020 Nov 11.

Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

Objective: This study aimed to assess the association of health-related quality of life (HRQoL) with financial burden among patients with non-Hodgkin's lymphoma (NHL) in China.

Methods: The data used for the analyses came from a nationwide survey to investigate the health status of patients with lymphomas in China. The EQ-5D and EORTC QLQ-C30 were used to assess the patients' HRQoL. Read More

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November 2020

Investigation of the value of ultrasound-guided core needle biopsy from pathologic lymph nodes to the diagnosis of lymphoma.

J Family Med Prim Care 2020 Jun 30;9(6):2801-2805. Epub 2020 Jun 30.

Department of Pathology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Introduction: In recent years, techniques with minimally invasive have been gradually developed and used in the diagnosis of lymphoma. Among minimally invasive techniques, core needle biopsy (CNB) has been widely accepted as an effective tool for the diagnosis of malignant lymphoma, carcinoma and deep tumors that are only accessible via CT or endoscopic-guided. This study was conducted to investigate of diagnostic value of ultrasound guided CNB in the diagnosis of lymphoma in all parts of the body compared to surgical excisional biopsy (SEB). Read More

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[A case report of congenital sensorineural deafness caused by novel mutation in Usher1C and related literature analysis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Jun;34(6):562-564

To study the clinical features and causes of congenital Usher hearing loss in one child. Clinical examination, audiological tests, visual acuity examination were conducted in the proband and its family members, and second-generation sequencing technology for deafness gene detection was employed. The proband exhibited profound sensorineural deafness(hearing threshold>90 dB nHL). Read More

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Efficacy and safety of second-generation CAR T-cell therapy in diffuse large B-cell lymphoma: A meta-analysis.

Mol Clin Oncol 2020 Oct 29;13(4):33. Epub 2020 Jul 29.

Oncology Center, International Medical Center, Jeddah 21451, Kingdom of Saudi Arabia.

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma (NHL), representing 30% of all lymphoma cases. Within the first 2-3 years following immunochemotherapy, 30-40% of patients will experience a relapse or a refractory disease, thereby exhibiting a poor prognosis. High-dose immunotherapy followed by autologous stem cell transplantation is the standard care for relapsed/refractory (RR) patients with DLBCL. Read More

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October 2020

Predictive value of serological factors, maximal standardized uptake value and ratio of Ki67 in patients diagnosed with non-Hodgkin's lymphoma.

Oncol Lett 2020 Oct 24;20(4):47. Epub 2020 Jul 24.

Department of Hematology, Shanghai Tongji Hospital, Shanghai Tongji University School of Medicine, Shanghai 200333, P.R. China.

The present study aimed to determine the prognostic value of serological factors, positron emission tomography/computed tomography maximal standardized uptake value (SUVmax) and the immunohistochemical index ratio of Ki67 (Ki67%) for patients diagnosed with non-Hodgkin's lymphoma (NHL). A total of 120 patients with NHL who received regular chemotherapy and underwent serological, radiological and pathological examinations at Shanghai Tongji Hospital between July 2015 and March 2019 were retrospectively analyzed. Spearman's correlation analysis was preformed to describe the associations between different categories of indicators. Read More

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October 2020

Circulating Epstein-Barr virus DNA and cell-free DNA in pediatric lymphomas.

Turk J Pediatr 2020 ;62(4):541-550

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background And Objectives: Quantification of serum Epstein-Barr virus (EBV) DNA and/or cell-free total DNA (cf-DNA) may become valuable sources for prognosis evaluation and monitoring treatment response in lymphomas. We aimed to investigate their roles as potential markers in pediatric Hodgkin (HL) and non- Hodgkin lymphomas (NHL).

Method: Between the years 2005-2008, 34 patients with HL and 45 with NHL were prospectively included. Read More

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January 2020

mRNA expression profile analysis reveals a C-MYC/miR-34a pathway involved in the apoptosis of diffuse large B-cell lymphoma cells induced by Yiqichutan treatment.

Exp Ther Med 2020 Sep 25;20(3):2157-2165. Epub 2020 Jun 25.

Cancer Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of adult non-Hodgkin's lymphoma (NHL). While DLBCL is sensitive to chemotherapy, a certain percentage of patients with DLBCL experience relapse. Previous studies have indicated that Yiqichutan treatment, which was developed to treat NHL, can inhibit DLBCL cell growth, but the mechanism is not fully understood. Read More

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September 2020

Event-free survival at 24 months is a robust surrogate endpoint for long-term survival in pediatric, adolescent, and adult T cell lymphoblastic lymphoma.

Ann Hematol 2020 Dec 25;99(12):2847-2857. Epub 2020 Jul 25.

Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing, 100021, China.

T cell lymphoblastic lymphoma (T-LBL) has an aggressive clinical behavior. To date, powerful and consistent prognostic factors have not been established for T-LBL. In this study, we first evaluated the association of event-free survival (EFS) at 24 months (EFS24) with overall survival (OS) in T-LBL patients. Read More

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December 2020

[CNS involvement and the feasibility of intratecal chemotherapy administration in patients with a nodal form of diffuse large B-cell lymphoma not otherwise specified. Data of prospective study].

Ter Arkh 2019 Jul 15;91(7):35-40. Epub 2019 Jul 15.

National Research Center for Hematology, Department of Intensive High-Dose Chemotherapy with Round-the-Clock and Day Hospital (IVHT with CS and DS).

Aim of the issue was to determine indications for intratecal chemotherapy drugs administration to prevent relapse of diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) involvement.

Materials And Methods: Since January 2009 to December 2018 102 patients with primary nodal DLBCL over 18 years old were treated in the National Research Center for Hematology, Moscow, Russian Federation. Diagnosis were established in all cases according to histological and immunohistochemical studies which made it possible to exclude the transformation of mature B-cell lymphoma into DLBCL. Read More

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Prehospital notification of injured patients presenting to a trauma centre in India: a prospective cohort study.

BMJ Open 2020 06 21;10(6):e033236. Epub 2020 Jun 21.

National Trauma Research Institute, The Alfred Hospital, Melbourne, VIC, Australia.

Objectives: To assess the effect of a mobile phone application for prehospital notification on resuscitation and patient outcomes.

Design: Longitudinal prospective cohort study with preintervention and postintervention cohorts.

Setting: Major trauma centre in India. Read More

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Long-term exposure to PM and its constituents and risk of Non-Hodgkin lymphoma in Denmark: A population-based case-control study.

Environ Res 2020 09 4;188:109762. Epub 2020 Jun 4.

Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen Ø, Denmark; Department of Environmental Science, Aarhus University, Roskilde, Denmark.

Background: Particulate matter (PM) air pollution is a complex mixture and the various PM constituents likely affect health differently. The literature on the relationships among specific PM constituents and the risk of cancer is sparse. In this study, we aimed to evaluate the association of PM and its constituents with the incidence of non-Hodgkin lymphoma (NHL) and the two main NHL subtypes. Read More

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September 2020

Changes in long term survival after diagnosis with common hematologic malignancies in the early 21st century.

Blood Cancer J 2020 05 13;10(5):56. Epub 2020 May 13.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Five-year survival has increased for many hematologic malignancies in the 21st century. However, whether this has translated into greater long-term survival is unknown. Here, we examine 10- and 20-year survival for patients with multiple myeloma (MM), acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML), chronic lymphoid leukemia (CLL), chronic myeloid leukemia (CML), non-Hodgkin lymphoma (NHL), and Hodgkin lymphoma (HL). Read More

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Alteration of Angiopoietin-Like Protein 4 Levels in Serum or Urine Correlate with Different Biochemical Markers in Hyperlipidemia-Related Proteinuria.

Biomed Res Int 2020 23;2020:5281251. Epub 2020 Mar 23.

Graduate School, Ningxia Medical University, Yinchuan City 750000, China.

Angiopoietin-like protein 4 (ANGPTL4) is widely known as a key regulator of lipid metabolism. We investigated the relationship between ANGPTL4 expression in serum or urine and blood lipid or urine protein levels of patients with hyperlipidemia- (HL-) related proteinuria. Sixty-eight patients with HL-related proteinuria (HL-Pro group), 68 patients with HL without proteinuria (HL-NPro group), 46 patients with non-HL-related proteinuria (NHL-Pro group), and 50 healthy control (Con) subjects were selected. Read More

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January 2021

Small Fiber Polyneuropathy in Hunner Lesion and Non-Hunner Lesion Interstitial Cystitis/Bladder Pain Syndrome.

Female Pelvic Med Reconstr Surg 2021 Jan;27(1):e91-e95

From the Beaumont Health.

Objective: This study aimed to determine whether small fiber polyneuropathy (SFPN) diagnosis differs between Hunner lesion interstitial cystitis/bladder pain syndrome (HL IC/BPS) and non-Hunner lesion IC/BPS (NHL IC/BPS).

Methods: This was a pilot study of 20 women with IC/BPS. Results from baseline questionnaires, such as Genitourinary Pain Index, Interstitial Cystitis Symptom Index/Interstitial Cystitis Problem Index (ICSI/ICPI), Patient Health Questionnaire-2, were collected. Read More

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January 2021

Descriptive Epidemiology of Lymphoma in Northern Iran: Results from the Golestan Registry 2004-2013.

Arch Iran Med 2020 03 1;23(3):150-154. Epub 2020 Mar 1.

Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.

Background: There is currently little known about the epidemiology of lymphomas in Iran. The aim of this paper is to describe the geographic and time variations in incidence rates of lymphomas in the Golestan province between 2004 and 2013.

Methods: The Golestan Population-based Cancer Registry (GPCR) routinely registers primary cancer patients from all sources (e. Read More

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MiR-132-3p serves as a tumor suppressor in mantle cell lymphoma via directly targeting SOX11.

Naunyn Schmiedebergs Arch Pharmacol 2020 11 10;393(11):2197-2208. Epub 2020 Feb 10.

Department of Pathology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.

Mantle cell lymphoma (MCL) is an uncommon type of non-Hodgkin's lymphoma (NHL), comprising about 6% of NHL cases. SOX11 is a member of the group C of Sry-related high-mobility group (HMG) box (Sox) transcription factors, which is ubiquitously expressed in approximate 90% MCL cases. However, the underlying mechanisms of the SOX11 expression aberration are not fully unveiled. Read More

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November 2020

Prognostic value and clinicopathological characteristics of PD-L1 overexpression in non-Hodgkin lymphoma: a meta-analysis.

BMC Cancer 2020 Jan 28;20(1):59. Epub 2020 Jan 28.

Department of Hematology, West China Hospital, Sichuan University, Chengdu, 610041, China.

Background: Programmed cell death ligand 1 (PD-L1) has already been detected in various carcinomas. In non-Hodgkin lymphoma (NHL), however, the prognostic value of PD-L1 overexpression remains unclear.

Methods: A meta-analysis of 2321 NHL patients from 12 studies was performed. Read More

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January 2020

The relationship between consumption of nitrite or nitrate and risk of non-Hodgkin lymphoma.

Sci Rep 2020 01 17;10(1):551. Epub 2020 Jan 17.

Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, Hangzhou, Zhejiang Province, 310003, P.R. China.

Epidemiologic studies of the relationship between nitrite or nitrate consumption and risk of non-Hodgkin lymphoma (NHL) remain controversial. The current meta-analysis aimed to reexamine the evidence and quantitatively evaluate that relationship. Manuscripts were retrieved from the Web of Science, Chinese National Knowledge Infrastructure and PubMed databases up to May 2019. Read More

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January 2020

pSTAT3 and MYC in Epstein-Barr virus-positive diffuse large B-cell lymphoma.

Malays J Pathol 2019 Dec;41(3):273-281

UCSI University, Faculty of Medicine and Health Sciences, Kuala Lumpur 56000, Malaysia.

Introduction: Epstein-Barr Virus (EBV) is associated with several B-cell non-Hodgkin's lymphoma (NHL), but the role of EBV in diffuse large B-cell lymphoma (DLBCL) is poorly defined. Several studies indicated the expression of phosphorylated STAT3 (pSTAT3) is predominant in EBV(+)- DLBCL, of which its activated form can promote the downstream oncogenes expression such as c-MYC. c-MYC gene rearrangements are frequently found in aggressive lymphoma with inferior prognosis. Read More

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December 2019

The prognostic value of platelet-lymphocyte ratio and neutrophil-lymphocyte ratio in the treatment response and survival of patients with peripheral T-cell lymphoma.

Leuk Lymphoma 2020 03 6;61(3):623-630. Epub 2019 Dec 6.

Senior Department of Hematology, The First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou, China.

Peripheral T-cell lymphoma (PTCL) is a rare and highly heterogeneous non-Hodgkin lymphoma (NHL). Although a few prognostic models have been put forward to predict the prognosis of PTCL, some patients with poor prognosis remain unidentified. Therefore, we conducted a retrospective study of 213 adult PTCL patients and assessed the prognostic role of platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR) in the complete response (CR) and survival of PTCL patients. Read More

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