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Effects of formic acid and lactic acid bacteria inoculant on main summer crop silages in Korea.

J Anim Sci Technol 2021 Jan 31;63(1):91-103. Epub 2021 Jan 31.

Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang 25354, Korea.

To improve the fermentation quality of silage and reduce the nutrients loss of raw materials during the ensiling process, silage additives are widely used. The effect of additives on silage is also affected by the species of crop. Therefore, this study was designed to explore the effects of formic acid (FA) and lactic acid bacterial inoculant on the quality of main summer crop silage. Read More

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January 2021

Combined use of epigallocatechin-3-gallate (EGCG) and caffeine in low doses exhibits marked anti-obesity synergy through regulation of gut microbiota and bile acid metabolism.

Food Funct 2021 May;12(9):4105-4116

Key Laboratory of Tea Science of Ministry of Education, National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, College of Horticulture, Hunan Agricultural University, Changsha, 410128, China. and Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha, 410128, China.

Epigallocatechin-3-gallate (EGCG) and caffeine constitute the most effective ingredients of weight loss in tea. However, whether combination of EGCG and caffeine exhibits anti-obesity synergy remains unclear. Here, we showed low-doses of EGCG and caffeine used in combination led to synergistic anti-obesity effects equivalent to those of high-dose EGCG. Read More

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Effects of Bacillus Coagulans on growth performance, antioxidant capacity, immunity function, and gut health in broilers.

Poult Sci 2021 Mar 27;100(6):101168. Epub 2021 Mar 27.

Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, Zhejiang Provincial Engineering Laboratory for Animal Health and Internet Technology, College of Animal Science and Technology, Zhejiang Agriculture & Forestry University, Hangzhou 311300, China. Electronic address:

This study evaluated the effects of Bacillus coagulans (B. coagulans) as an alternative to antibiotics on growth performance, antioxidant capacity, immunity function and gut health in broilers. A total of 480 one-day-old broilers were randomly divided into 3 treatments with 8 replicates comprising 20 broilers each. Read More

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Role of Indole-3-Acetic Acid in NAFLD Amelioration After Sleeve Gastrectomy.

Obes Surg 2021 May 10. Epub 2021 May 10.

Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: This study aimed to investigate the weight-independent mechanism of sleeve gastrectomy on the relief of nonalcoholic fatty liver disease (NAFLD).

Methods: A total of 58 obese patients who had undergone sleeve gastrostomy (SG) were recruited. Plasma levels of indole-3-acetic acid (I3A), a metabolite from gut microbiota before and after SG were investigated. Read More

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Substrate-driven differences in tryptophan catabolism by gut microbiota and Aryl hydrocarbon Receptor activation.

Mol Nutr Food Res 2021 May 8:e2100092. Epub 2021 May 8.

Food Quality and Design Group, Department of Agrotechnology and Food Sciences, Wageningen University, P.O. Box 17, Wageningen, 6700 AA, the Netherlands.

Scope: This study aims to investigate the effect of tryptophan sources on tryptophan catabolism by gut microbiota and the Aryl hydrocarbon Receptor (AhR) activation.

Methods And Results: Four substrates (free tryptophan, soybean protein, single and clustered soybean cells) containing an equimolar amount of tryptophan, but with a different bioaccessibility were studied using in vitro batch fermentation. Tryptophan catabolites were identified by LC-MS/MS. Read More

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Inoculation with Bacillus amyloliquefaciens and mycorrhiza confers tolerance to drought stress and improve seed yield and quality of soybean plant.

Physiol Plant 2021 May 8. Epub 2021 May 8.

Department of Agricultural Microbiology, Faculty of Agriculture, Mansoura University, Mansoura, Egypt.

The present study aimed to evaluate the effect of Bacillus amyloliquefaciens and/or Arbuscular Mycorrhizal Fungi (AMF) as natural biofertilizers on biomass, yield and seed nutritive quality of soybean (Giza 111). The conditions investigated include a well-watered (WW) control and irrigation withholding at the seed development stage (R5, after 90 days from sowing) (DS). Co-inoculation with B. Read More

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Profiling metal contamination from ultramafic sediments to biota along the Albanian shoreline of Lake Ohrid (Albania/Macedonia).

J Environ Manage 2021 May 4;291:112726. Epub 2021 May 4.

Université de Lorraine, CNRS, LIEC, F-57000, Metz, France.

Ultramafic sediments exhibit high levels of geogenically-derived and potentially toxic metals, with Ni, Cr and Co often exceeding benchmark values. As yet, a holistic understanding of the bioavailability, mobility, potential ecotoxicity and trophic transfer of trace elements in both benthic and pelagic food chains in aquatic ultramafic environments (UME) is lacking. We investigated potential environmental health issues due to metal contamination by jointly implementing chemical, ecological and toxicological tools, along the Albanian shoreline of Lake Ohrid. Read More

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Aldoximes are precursors of auxins in Arabidopsis and maize.

New Phytol 2021 May 6. Epub 2021 May 6.

Horticultural Sciences Department, University of Florida, Gainesville, 32611.

Two natural auxins, phenylacetic acid (PAA) and indole-3-acetic acid (IAA), play crucial roles in plant growth and development. One route of IAA biosynthesis uses the glucosinolate intermediate indole-3-acetaldoxime (IAOx) as a precursor, which is thought to occur only in glucosinolate-producing plants in Brassicales. A recent study showed that overproducing phenylacetaldoxime (PAOx) in Arabidopsis increases PAA production. Read More

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A combination of Lactobacillus buchneri and Pediococcus pentosaceus extended the aerobic stability of conventional and BMR-corn hybrids ensiled at low dry matter concentrations by causing a major shift in their bacterial and fungal community.

J Anim Sci 2021 May 7. Epub 2021 May 7.

Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA.

We evaluated the effects of applying a combination inoculant to 4 corn hybrids harvested at high moisture on their nutritive value and microbial populations. The treatment design was the factorial combination of corn hybrids ensiled with (INO) and without (CON) inoculant. The hybrids were TMF2R737 (MCN), F2F817 (MBR), P2089YHR (PCN), and PI144XR (PBR), ensiled at dry matter (DM) concentrations of 30. Read More

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Advances in the separation of gangliosides by counter-current chromatography (CCC).

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Apr 9;1174:122701. Epub 2021 Apr 9.

Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta T6G 2P5, Canada.

Gangliosides play critical roles in the development of many progressive diseases. Due to their structural diversity, efficient methods are needed to separate individual gangliosides for studies of their functions, and for use as standards in the analysis of ganglioside mixtures. This proof-of-concept study reports a useful analytical-semi-preparative scale counter-current chromatography (CCC) enrichment of multiple ganglioside homologues of various species and classes at the milligram level. Read More

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Aronia berry polyphenols have matrix-dependent effects on the gut microbiota.

Food Chem 2021 Apr 20;359:129831. Epub 2021 Apr 20.

University of Wisconsin-Madison, Department of Food Science, 1605 Linden Dr., Madison, WI 53706, USA. Electronic address:

The objective of this study was to determine the extent that the aronia berry matrix affects gut microbiota composition, fecal short chain fatty acids (SCFAs), and colonic anthocyanins in healthy mice. C57BL/6J mice were fed AIN-93 M control diet (C) or C with whole aronia berry (AB), aronia extract (AE), or polyphenol-depleted AB (D) at the expense of cornstarch. After one week of feeding, AB and D increased fecal anthocyanins more than AE. Read More

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Interference of with in the treatment of infected burns in Wistar rats.

Iran J Basic Med Sci 2021 Feb;24(2):143-149

Department of Microbiology, Damghan Branch, Islamic Azad University, Damghan, Iran.

Objectives: Burns are the most common type of trauma with a high mortality rate worldwide. The use of modern and natural medicines, especially probiotic products, has been recently considered for cutaneous wound healing. The present study was designed to investigate the effect of on wound healing caused by . Read More

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February 2021

Effect of Oxygen-Containing Group on the Catalytic Performance of Zn/C Catalyst for Acetylene Acetoxylation.

Nanomaterials (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

College of Chemistry & Chemical Engineering, Yantai University, Yantai 264010, China.

In this study, a series of activated carbon-based supports with different oxygen-containing groups (OCGs) proportions were obtained via thermal treatment in an ozone flow. Semiquantitative analyses indicated that the performance of the catalyst attained a maximum after 30 min of treatment with ozone flow, and had a positive correlation with the content ratios of carboxyl and hydroxyl groups. Further, temperature-programmed desorption analysis demonstrated that the high performance (63% acetic acid conversion) of the prepared catalyst for the acetoxylation of acetylene could be ascribed to the reduced strength of increased capacity of acetylene adsorption. Read More

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The Use of Yeast Mixed Cultures for Deacidification and Improvement of the Composition of Cold Climate Grape Wines.

Molecules 2021 Apr 30;26(9). Epub 2021 Apr 30.

Department of Fermentation Technology and Microbiology, Faculty of Food Technology, University of Agriculture in Krakow, ul. Balicka 122, 30-149 Krakow, Poland.

Interest in the use of non- yeast in mixed cultures is increasing due to the perceived improvement in the quality and complexity of the resulting wines. The aim of the study was to determine the ability of monocultures and mixed yeast cultures for deacidification and improvement of the composition of cold climate grape wines. Fermentation of grape musts with increased total acidity was carried out with the use of monocultures of MH020215 (Sc), 749 (Zb) and MG970690 (Mp), and their mixed cultures, inoculated simultaneously and sequentially. Read More

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Granulocyte-colony stimulating factor, a potential candidate for the treatment of Parkinson's disease.

J Neurosurg Sci 2021 May 3. Epub 2021 May 3.

Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China -

Background: Granulocyte colony-stimulating factor (G-CSF) activates the PI3K/Akt pathway to exert neuroprotective effects. The current study aimed to determine if G-CSF reverses behavioral deficits, even after motor malfunction occurs in Paraquat (PQ)-treated mice.

Methods: Male C57BL/6 mice (8 weeks old) were divided into 3 groups: PQ + G-CSF-treated group (n=8); PQ + saline-treated group (n=8); and saline-treated control group (n=8). Read More

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Halotolerant bacteria isolated from extreme environments induce seed germination and growth of chia (Salvia hispanica L.) and quinoa (Chenopodium quinoa Willd.) under saline stress.

Ecotoxicol Environ Saf 2021 Apr 30;218:112273. Epub 2021 Apr 30.

Instituto de Investigaciones para la Industria Química (INIQUI), Universidad Nacional de Salta (UNSa) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Salta, Argentina; Facultad de Ciencias Naturales, UNSa, Salta, Argentina. Electronic address:

The aim of the study was to characterize halotolerant bacteria and to evaluate their plant growth promotion potential on chia and quinoa seedlings under saline stress. Isolated microorganisms were evaluated for nitrogen fixation, phosphate solubilization, and production of siderophores and indole acetic acid. Three strains and two consortia were selected: Halomonas sp. Read More

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Impact of feeding modified soy protein concentrate in the starter phase on growth performance and gastrointestinal responses in broiler chickens through to day 42 of age.

Poult Sci 2021 Mar 21;100(6):101147. Epub 2021 Mar 21.

Research and Development, TripleA A/S, Hornsyld, Denmark.

Growth performance and physiological responses of feeding modified soy protein concentrate (MSPC, 72% CP) in the starter phase were investigated. A total of 1,216 d old male Ross x Ross 708 broiler chicks were placed in 32 floor pens based on BW, fed one of 4 (n = 8) corn-soybean meal-based diets formulated with 0, 7.7, 10. Read More

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Impact of a fermented soy beverage supplemented with acerola by-product on the gut microbiota from lean and obese subjects using an in vitro model of the human colon.

Appl Microbiol Biotechnol 2021 May 3;105(9):3771-3785. Epub 2021 May 3.

Centre for Healthy Eating & Food Innovation, Maastricht University - Campus Venlo, Villafloraweg 1, 5928 SZ, Venlo, The Netherlands.

The aim of this study was to evaluate the effects of soy-based beverages manufactured with water-soluble soy extract, containing probiotic strains (Lactobacillus acidophilus LA-5 and Bifidobacterium longum BB-46) and/or acerola by-product (ABP) on pooled faecal microbiota obtained from lean and obese donors. Four fermented soy beverages (FSs) ("placebo" (FS-Pla), probiotic (FS-Pro), prebiotic (FS-Pre), and synbiotic (FS-Syn)) were subjected to in vitro digestion, followed by inoculation in the TIM-2 system, a dynamic in vitro model that mimics the conditions of the human colon. Short- and branched-chain fatty acids (SCFA and BCFA) and microbiota composition were determined. Read More

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Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.

Front Pharmacol 2021 15;12:642400. Epub 2021 Apr 15.

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

The novel Traditional Chinese Medicine Ramulus Mori (Sangzhi) alkaloid tablets (SZ-A) are approved by The China National Medical Products Administration for the treatment of type 2 diabetes mellitus (T2DM). However, the extensive pharmacological characteristics and the underlying mechanism are unknown. This study investigated the mechanisms by which SZ-A ameliorates glucose metabolism in KKAy mice, an animal model of T2DM. Read More

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Effect of lactic acid fermentation of watermelon juice on its sensory acceptability and volatile compounds.

Food Chem 2021 Apr 19;358:129809. Epub 2021 Apr 19.

Research Unit VEG-i-TEC, Department of Food Technology, Safety and Health, Ghent University Campus Kortrijk, Graaf Karel de Goedelaan 5, 8500 Kortrijk, Belgium. Electronic address:

Fermentation increases food shelf-life but is characterized by changes that affect product's perception. Watermelon juice was fermented with Lactobacillus plantarum (WJ-LP), L. rhamnosus (WJ-LR), L. Read More

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The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation.

BMC Pharmacol Toxicol 2021 May 1;22(1):24. Epub 2021 May 1.

Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Background: Surgical procedures cause perioperative immunosuppression and neuroendocrine stress, exerted by activation of the autonomic nervous system and the hypothalamic-pituitary-adrenal axis. The acetylcholinesterase inhibitor (ACHEI); neostigmine, is known clinically for its analgesic effect in the perioperative phases proving high efficacy; besides possessing anti-inflammatory properties controlling immune cells and cytokine level. Hence, this study evaluated and compared the analgesic and anti-inflammatory activities of the combination of selective Cox-2 inhibitor; celecoxib, with neostigmine versus a combination of the non-selective Cox inhibitor; diclofenac, with neostigmine; in different experimental models of analgesia and inflammation in rats. Read More

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CPPU may induce gibberellin-independent parthenocarpy associated with PbRR9 in 'Dangshansu' pear.

Hortic Res 2020 May 1;7(1):68. Epub 2020 May 1.

College of Horticulture, Northwest A&F University, Taicheng, Road No.3, Yangling, Shaanxi, Province, China.

Parthenocarpy is a valuable trait in self-incompatible plants, such as pear. N-(2-chloro-4-pyridyl)-N'-phenylurea (CPPU), a synthetic cytokinin analog, can induce parthenocarpy in pear (Pyrus spp.), but the mechanism of induction is unclear. Read More

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Interaction of gibberellin and other hormones in almond anthers: phenotypic and physiological changes and transcriptomic reprogramming.

Hortic Res 2021 May 1;8(1):94. Epub 2021 May 1.

College of Forestry and Horticulture, Xinjiang Agricultural University, Urumqi, 830052, China.

Low temperature causes anther dysfunction, severe pollen sterility and, ultimately, major yield losses in crop plants. Previous studies have shown that the gibberellic acid (GA) metabolic pathway plays an important role in this process by regulating tapetum function and pollen development. However, the interaction mechanism of GA with other hormones mediating anther development is still unclear. Read More

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Phosphate-solubilizing bacterium Burkholderia sp. strain N3 facilitates the regulation of gene expression and improves tomato seedling growth under cadmium stress.

Ecotoxicol Environ Saf 2021 Jul 28;217:112268. Epub 2021 Apr 28.

Institute of Horticulture, Anhui Academy of Agricultural Sciences, Hefei 230031 Anhui Province, China.

Cadmium (Cd) is among the most toxic heavy metals in soils. The ways by which tomato plants inoculated with a phosphate-solubilizing bacterium (PSB) respond to Cd and regulate gene expression remain unclear. We investigated hormone metabolism and genes involved in Cd resistance in tomato seedlings inoculated with the PSB strain N3. Read More

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Screen, Notify, See, and Treat: Initial Results of Cervical Cancer Screening and Treatment in Rwanda.

JCO Glob Oncol 2021 Apr;7:632-638

University of Global Health Equity, Kigali, Rwanda.

Purpose: To describe the first year results of Rwanda's Screen, Notify, See, and Treat cervical cancer screening program, including challenges encountered and revisions made to improve service delivery.

Methods: Through public radio broadcasts, meetings of local leaders, church networks, and local women's groups, public awareness of cervical cancer screening opportunities was increased and community health workers were enlisted to recruit and inform eligible women of the locations and dates on which services would be available. Screening was performed using human papillomavirus (HPV) DNA testing technology, followed by visual inspection with acetic acid (VIA), and cryotherapy, biopsy, and surgical treatment for those who tested HPV-positive. Read More

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Orchestration of plant development and defense by indirect crosstalk of SA and BR signaling through a transcription factor GhTINY2.

J Exp Bot 2021 Apr 30. Epub 2021 Apr 30.

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, Hubei, China.

Salicylic acid (SA) and brassinosteroids (BRs) are well known to regulate diverse processes of plant development and stress responses, but the mechanisms by which these phytohormones mediate the growth-defense trade-off is largely unclear. In addition, little is known about the roles of DEHYDRATION RESPONSIVE ELEMENT BINDING (DREB) transcription factors, especially in biotic stress and plant growth. Here, we identified a cotton (Gossypium hirsutum) APETALA2/ETHYLENE RESPONSIVE FACTOR (AP2/ERF) gene GhTINY2 which is strongly induced by Verticillium dahliae. Read More

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Effect of Fermented Products Produced by on the Growth Performance and Cecal Microbial Community of Broilers under Coccidial Challenge.

Animals (Basel) 2021 Apr 26;11(5). Epub 2021 Apr 26.

Department of Biotechnology and Animal Science, National Ilan University, Yilan 26047, Taiwan.

This study investigated the effects of fermented products produced by (fermented products) on the growth performance and cecal microbial community in broilers exposed to coccidial challenge. A total of 108 one-day-old male broiler chicks (Ross 308) were randomly allotted to one of three treatments. Each treatment was distributed into six replicate cages with six birds each. Read More

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Concentration with Nanofiltration of Red Wine Cabernet Sauvignon Produced from Conventionally and Ecologically Grown Grapes: Effect on Volatile Compounds and Chemical Composition.

Membranes (Basel) 2021 Apr 27;11(5). Epub 2021 Apr 27.

Faculty of Food Technology Osijek, Josip Juraj Strossmayer University, F. Kuhača 18, 31000 Osijek, Croatia.

Ecological viticulture represent an upward trend in many countries. Unlike conventional viticulture, it avoids the use of chemical fertilizers and other additives, minimizing the impact of chemicals on the environment and human health. The aim of this study was to investigate the influence of nanofiltration (NF) process on volatiles and chemical composition of conventional and ecological Cabernet Sauvignon red wine. Read More

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CE 100 Inhibits Root Rot Diseases ( spp.) and Promotes Growth of Japanese Cypress ( Endlicher) Seedlings.

Microorganisms 2021 Apr 13;9(4). Epub 2021 Apr 13.

Department of Forest Resources, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Korea.

Root rot diseases, caused by phytopathogenic oomycetes, spp. cause devastating losses involving forest seedlings, such as Japanese cypress ( Endlicher) in Korea. Plant growth-promoting rhizobacteria (PGPR) are a promising strategy to control root rot diseases and promote growth in seedlings. Read More

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Bacterial Indole-3-Acetic Acid Influences Soil Nitrogen Acquisition in Barley and Chickpea.

Plants (Basel) 2021 Apr 16;10(4). Epub 2021 Apr 16.

Department of Life Science, Faculty of Natural Sciences, Imperial College, London SW7 2AZ, UK.

Farming of barley and chickpea is nitrogen (N) fertilizer dependent. Using strategies that increase the nitrogen use efficiency (NUE) and its components, nitrogen uptake efficiency (NUpE) and nitrogen utilization efficiency (NUtE) would reduce the N fertilizer application in the soil and its adverse environmental effects. We evaluated the effects of three different strains of diazotroph ( SSN1, SGM81, and M5a1) to understand the role of biological nitrogen fixation (BNF) and bacterial indole-3-acetic acid (IAA) on NUE of the plants. Read More

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