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[Inflammatory Bowel Disease - Challenges in the Workplace and Support for Coping with Disease].

Rehabilitation (Stuttg) 2021 Sep 20. Epub 2021 Sep 20.

Institut für Sozialmedizin und Epidemiologie, Universität zu Lübeck, Lübeck.

Purpose: Patients with inflammatory bowel diseases (IBD) are often impaired in their ability to be employed due to IBD symptoms. The aim of this study was to explore work-related problems and support requested by IBD patients and develop rehabilitation programs meeting their needs.

Methods: A total of 235 IBD patients (97 rehabilitants, 138 outpatients) completed a questionnaire assessing disease-specific impairments, work-related concerns and the need for support services. Read More

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September 2021

Seroepidemiology of TORCH Infections among 1.7 Million Women of Childbearing Age in Rural China: A Population-Based Cross-Sectional Study.

Am J Trop Med Hyg 2021 Sep 20. Epub 2021 Sep 20.

Department of Clinical Laboratory Medicine, Capital Medical University Affiliated Beijing Shijitan Hospital, Beijing, China.

We conducted a national seroepidemiological study of the TORCH (Toxoplasma gondii [TOX], Rubella [RV], Cytomegalovirus [CMV], and Herpes Simplex Virus) in rural women to provided updated baseline data on TORCH prevalence. A total of 1,541,329 women of childbearing age were gathered from 2010 to 2012 in China. Of these, 858,072 women were tested positive for anti-RV IgG antibodies, 602,251 women were tested positive for anti-CMV antibodies, and 40,055 women were tested positive for anti-TOX antibodies. Read More

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September 2021

Response of Calamagrostis angustifolia to burn frequency and seasonality in the Sanjiang Plain wetlands (Northeast China).

J Environ Manage 2021 Sep 17;300:113759. Epub 2021 Sep 17.

Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Shengbei Street 4888, 130102, Changchun, China. Electronic address:

Fire is an important disturbance in many wetlands, which are key carbon reservoirs at both regional and global scales. However, the effects of fire on wetland vegetation biomass and plant carbon dynamics are poorly understood. We carried out a burn experiment in a Calamagrostis angustifolia wetland in Sanjiang Plain (Northeast China), which is widespread wetland type in China and frequently exposed to fire. Read More

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September 2021

Prenatal exposure to paraquat and nanoscaled TiO aerosols alters the gene expression of the developing brain.

Chemosphere 2021 Sep 16;287(Pt 3):132253. Epub 2021 Sep 16.

IGFL, Functional Genomics of Thyroid Hormone Signaling Group, Lyon, France. Electronic address:

Nanopesticides are innovative pesticides involving engineered nanomaterials in their formulation to increase the efficiency of plant protection products, while mitigating their environmental impact. Despite the predicted growth of the nanopesticide use, no data is available on their inhalation toxicity and the potential cocktail effects between their components. In particular, the neurodevelopmental toxicity caused by prenatal exposures might have long lasting consequences. Read More

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September 2021

Comparative study on polychlorinated biphenyl sorption to activated carbon and biochar and the influence of natural organic matter.

Chemosphere 2021 Sep 13;287(Pt 3):132239. Epub 2021 Sep 13.

Department of Civil and Environmental Engineering, School of Civil Engineering, Beijing Jiaotong University, Beijing, 100044, China.

The sorption isotherms of polychlorinated biphenyls (PCBs) on carbons (coal based activated carbon named AC and hardwood derived biochar named BC) and natural organic matter (NOM) loaded carbons were examined and carbon-water partition coefficients (K) were calculated. The purpose was to accurately predict the effectiveness of in-situ carbon treatments on the sediment impacted with hydrophobic organic chemicals (HOCs). For 1 month sorption, AC K values were significantly higher than BC, corresponding to the much larger surface area (particularly in mesopores) for AC. Read More

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September 2021

Modest decrease in severity of obesity in adolescence associates with low arterial stiffness.

Atherosclerosis 2021 Sep 14;335:23-30. Epub 2021 Sep 14.

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.

Background And Aims: Childhood obesity is associated with cardiovascular risk factors (CVRF), subclinical cardiovascular phenotypes (carotid intima-media thickness, cIMT; pulse-wave velocity, PWV; and carotid elasticity), and adult cardiovascular disease (CVD) mortality. In youth with obesity (body mass index, BMI ≥95th centile), we investigated associations between changes in adiposity and CVRF in early adolescence and subclinical cardiovascular phenotypes in late adolescence.

Methods: Participants had adiposity measures (the severity of obesity in percentage >95th BMI-centile (%>95th BMI-centile)), waist circumference (WC), percentage total body fat (%BF) and CVRF (systolic blood pressure, SBP; glycoprotein acetyls, GlycA; and low-density lipoprotein cholesterol) assessed in early (mean age 10. Read More

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September 2021

At-risk early adolescents profiles in the community: A cluster analysis using the strengths and difficulties questionnaire.

Psychiatry Res 2021 Sep 11;305:114209. Epub 2021 Sep 11.

Department of Educational, Psychological and Communication Sciences, Suor Orsola Benincasa University, Italy.

Early adolescence, with its several changes and demands, represents a delicate period of life. Several studies highlighted that during early adolescence, emotional and behavioral problems tend to increase. Using a person-centered approach, the present study explored the emotional and behavioral functioning profiles in a sample of Italian preadolescent students. Read More

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September 2021

The feasibility of medical unmanned aerial systems in suburban areas.

Am J Emerg Med 2021 Aug 31;50:532-545. Epub 2021 Aug 31.

University of Virginia, USA. Electronic address:

Out-of-Hospital Cardiac Arrests (OHCA) are one of the biggest challenges facing medical systems world-wide. Each year, more than 420,000 Americans experience cardiac arrests with a survival rate of approximately 10%. A large challenge to treating OHCA continues to be rapid access to AEDs which can increase survival rates up to 40%. Read More

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Dynamic of CO, CH and NO in the Guadalquivir estuary.

Sci Total Environ 2021 Sep 11;805:150193. Epub 2021 Sep 11.

Dpto. Química-Física, INMAR, Facultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, Campus Universitario Río San Pedro, 11510 Puerto Real, Cádiz, Andalucía, Spain.

The concentration of dissolved CH and NO, as well as the partial pressure of CO (pCO) were studied in the Guadalquivir estuary. Samples were taken in March and April 2018 and 2019, under different rainy and tidal conditions. The available database for summer 2017 (Sierra et al. Read More

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September 2021

Transient and continuous effects of indoor human movement on nanoparticle concentrations in a sitting person's breathing zone.

Sci Total Environ 2021 Aug 28;805:149970. Epub 2021 Aug 28.

Anhui Province Key Laboratory of Human Safety, Hefei, Anhui Province 230601, PR China.

Particle concentration in a sitting person's breathing zone can be influenced by human movement around the person, and the transient and continuous effects may differ. In this study, a set of full-scale experiments was conducted to sample the nanoparticle concentration in the breathing zone of a sitting thermal breathing manikin (STBM). The transient fluctuation of the nanoparticle concentration was recorded continuously and analyzed. Read More

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On the development of a regional climate change adaptation plan: Integrating model-assisted projections and stakeholders' perceptions.

Sci Total Environ 2021 Sep 14;805:150320. Epub 2021 Sep 14.

Centre for the Research and Technology of Agro-environmental Sciences, CITAB, Universidade de Trás-os-Montes e Alto Douro, UTAD, 5000-801 Vila Real, Portugal.

Climate change is expected to have strong social-ecological implications, with global but especially regional and local challenges. To assess the climatic vulnerability of a given territory, it is necessary to evaluate its exposure to climate change and its adaptive capacity. This study describes the development of an Action Plan for Adapting to Climate Change in the Tâmega and Sousa Region, a mountainous inter-municipal community in the North of Portugal. Read More

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September 2021

Do soil conservation practices exceed their relevance as a countermeasure to greenhouse gases emissions and increase crop productivity in agriculture?

Sci Total Environ 2021 Sep 15;805:150337. Epub 2021 Sep 15.

Department of Soil Science, Faculty of Agriculture, Bahauddin Zakariya University, Multan, Punjab, Pakistan.

Globally, agriculture sector is the significant source of greenhouse gases (GHGs) emissions into the atmosphere. To achieve the goal of limiting or mitigating these emissions, a rigorous abatement strategy with an additional focus on improving crop productivity is now imperative. Replacing traditional agriculture with soil conservation-based farming can have numerous ecological benefits. Read More

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September 2021

Multimedia fate model and risk assessment of typical antibiotics in the integrated demonstration zone of the Yangtze River Delta, China.

Sci Total Environ 2021 Sep 14;805:150258. Epub 2021 Sep 14.

Department of Civil, Architectural and Environmental Engineering, The University of Texas at Austin, Austin, TX, 78712,USA.

Due to the widespread consumption of antibiotics by humans and animals, antibiotic residues from human and animal excrements are released into the environment through domestic sewage and breeding wastewater, which ultimately affect the ecological environment and human health. In this study, the concentrations of 10 antibiotics in the air, water, soil, and sediment from 2013 to 2019 in Qingpu District of the integrated demonstration zone of the Yangtze River Delta were predicated by developing a dynamic Level IV fugacity model. The influence of seasonal environmental factors (e. Read More

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September 2021

Modifiable Risk Factors Increase Length of Stay and 90-Day Cost of Care After Shoulder Arthroplasty.

J Shoulder Elbow Surg 2021 Sep 17. Epub 2021 Sep 17.

Background: Baseline health conditions can negatively impact cost of care and risk of complications after joint replacement, necessitating additional care and incurring higher costs. Bundled payments have been utilized for hip and knee replacement and CMS (Centers for Medicare and Medicaid Services) is testing bundled payments for upper extremity arthroplasty. The purpose of this study was to determine the impact of pre-defined modifiable risk factors (MRF) on total encounter charges, hospital length of stay (LOS), related emergency department (ED) visits and charges, and related hospital readmissions within 90 days after shoulder arthroplasty. Read More

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September 2021

Dural Venous Sinus Variations in Idiopathic Subarachnoid Hemorrhage: a New Indicator of the Venous Origin with Diagnostic Utility?

World Neurosurg 2021 Sep 17. Epub 2021 Sep 17.

Department of Neurological Surgery, Germans Trias i Pujol University Hospital, Badalona, Spain. Electronic address:

Objective: Venous hypertension associated with a primitive basal vein of Rosenthal (BVR) has been noted as the most likely cause of idiopathic subarachnoid hemorrhage (iSAH). Other types of venous drainage variations have been scarcely studied but may further explain the cases not associated with a BVR anomaly. Our aim was to investigate if dural venous sinus (DVS) anomalies are related with iSAH. Read More

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September 2021

Outcomes Following the Endovascular Treatment of Renal Artery Stenosis Caused by Fibromuscular Dysplasia: A Systematic Review and Meta-Analysis.

Ann Vasc Surg 2021 Sep 17. Epub 2021 Sep 17.

Department of Vascular Surgery, The 3rd Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.

Objective: Renal artery revascularization has been performed to improve blood pressure control and to cure hypertension in patients with renal artery fibromuscular dysplasia (RAFMD). We herein conducted a systematic review and meta-analysis of studies assessing outcomes associated with the treatment of hypertensive RAFMD patients via endovascular angioplasty in order to offer an up-to-date overview of the relative costs and benefits of this approach to revascularization in RAFMD patients.

Methods: We systematically searched the PubMed and Embase databases and the Cochrane Central Register for Controlled Trials to identify relevant studies published as of January 15, 2020. Read More

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September 2021

Effects of the Methyl Donors Supplementation on Hippocampal Oxidative Stress, Depression and Anxiety in chronically High Fructose-Treated Rats.

Neuroscience 2021 Sep 17. Epub 2021 Sep 17.

Laboratory of Genetics, Neuro-endocrinology and Biotechnology, Department of Life Sciences, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco.

Evidence suggests that oxidative stress plays an important role in the development of anxiety and depression. The aim of the present study was to investigate whether Methyl Donors Supplementation could exert beneficial effects on hippocampal oxidative stress, anxiety and depression in chronically high fructose-treated rats, a new animal model of anxiety and mood disorders. Rats were divided into two groups and treated for 10 weeks as follows: Group 1 represents the control group and Group 2 was treated with 23 % fructose. Read More

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September 2021

Association of obesity and incidence of third, fourth, and sixth cranial nerve palsies.

Am J Ophthalmol 2021 Sep 17. Epub 2021 Sep 17.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

Study Design: Retrospective cohort study OBJECTIVE: To assess the association between obesity and the development of third, fourth, and sixth cranial nerve palsy (CNP).

Methods: We analyzed a cohort of 4,067,842 adults aged between 20 and 90 years who underwent health checkups within the National Health Insurance Service between January 1 and December 31, 2009. The participants were followed until December 31, 2017. Read More

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September 2021

Assessment of the Role and Timing of Glaucoma Surgery in Boston Keratoprosthesis Type 1 Patients.

Am J Ophthalmol 2021 Sep 17. Epub 2021 Sep 17.

Department of Ophthalmology, Centre hospitalier de l'Université de Montréal (CHUM), 1051 Sanguinet, D.01.2273, Montreal (Quebec) H2 × 3E4, Canada. Electronic address:

Purpose: To determine the role and optimal timing of glaucoma surgery in relation to Boston keratoprosthesis type 1 (KPro) implantation.

Design: Retrospective, comparative, non-randomized clinical study.

Methods: Single-center study of a total of 100 eyes (100 patients) implanted with a KPro between 2008-2017 and diagnosed with glaucoma before or after KPro. Read More

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September 2021

Effect of Regular Aerobic Training on Serum C-Reactive Protein and IL-6 Levels in Obese Women.

P R Health Sci J 2021 Jun;40(2):81-86

Department of Physiology, Division of Sports Physiology, Faculty of Medicine, Çukurova University, Adana, Turkey.

Objective: This study's objective was to evaluate interleukin-6 (IL-6) and C-reactive protein (CRP) responses and performance changes in obese women after 8 weeks of aerobic training with an intensity of 50 to 60% of their individual maximum oxygen uptake (VO2).

Methods: A total of 18 sedentary women with an average age of 44.3 (± 1. Read More

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The effect of the content of ApoA-I in peripheral blood on the state of immune homeostasis in people living in extreme climatic conditions of the Arctic.

Klin Lab Diagn 2021 Sep;66(9):539-545

Federal State Budgetary Institution of Science N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences.

The paper presents data on the impacts of the content of ApoA-I in peripheral blood on the state of immune homeostasis in people living in extreme climatic conditions of the Arctic. From the village of Revda, Murmansk region, 191 people were examined, 160 women and 31 men, aged from 21 to 55 years. The analysis of the results was carried out depending on the level of ApoA-I content: 111 examined people had a low content of ApoA-I (< 115 mg/dl) and 80 people had a concentration of ApoA-I - within the physiological norm (115-220 mg/dl). Read More

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September 2021

Cultivable microalgae diversity from a freshwater aquaculture filtering system and its potential for polishing aquaculture derived water streams.

J Appl Microbiol 2021 Sep 20. Epub 2021 Sep 20.

Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.

Aims: Microalgae are ubiquitous in aquatic environments, including aquaculture farms, but few studies have delved into their phytoplankton diversity and bioremediation potential. In this study, the cultivable phytoplankton of a rainbow trout freshwater aquaculture farm was isolated, phylogenetically analysed and used to assemble a consortium to polish an aquaculture derived effluent, with low concentrations of ammonium, nitrite, and nitrate.

Methods And Results: Through standard plating in different selective media, a total of 15 microalgae strains were isolated from sludge from a rotary drum filtering system which removes suspended solids from the water exiting the facility. Read More

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September 2021

Serum Vitamin D: Correlates of Baseline Concentration and Response to Supplementation in VITAL-DKD.

J Clin Endocrinol Metab 2021 Sep 20. Epub 2021 Sep 20.

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA.

Context: The effect of daily vitamin D supplementation on the serum concentration of vitamin D (the parent compound) may offer insight into vitamin D disposition.

Objective: To assess the total serum vitamin D response to vitamin D3 supplementation and whether it varies according to participant characteristics. To compare results with corresponding results for total serum 25-hydroxyvitamin D (25(OH)D), which is used clinically and measured in supplementation trials. Read More

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September 2021

Interactions between running volume and running pace on injury occurrence in recreational runners: A secondary analysis.

J Athl Train 2021 Sep 20. Epub 2021 Sep 20.

aDepartment of Public Health, Aarhus University, Aarhus 8000, DK.

Context The combination of an excessive increase in running pace and volume is essential to consider when investigating associations between running and running-related injury. Objectives The purpose of the present study was to complete a secondary analysis on a dataset from a randomized trial, to investigate the interactions between relative or absolute weekly changes in running volume and running pace on running injury occurrence among a cohort of injury-free recreational runners in Denmark. Design Prospective cohort study Setting Running volume and pace were collected during a 24-week follow-up using global positioning systems (GPS) data. Read More

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September 2021

Xylanase impact beyond performance: A microbiome approach in laying hens.

PLoS One 2021 20;16(9):e0257681. Epub 2021 Sep 20.

Animal Nutrition and Health, Kemin Europa N.V., Herentals, Antwerp, Belgium.

Anti-nutritional compounds such as non-starch polysaccharides (NSP) are present in viscous cereals used in feed for poultry. Therefore, exogenous carbohydrases are commonly added to monogastric feed to degrade these NSP. Our hypothesis is that xylanase not only improves laying hen performance and digestibility, but also induces a significant shift in microbial composition within the intestinal tract and thereby might exert a prebiotic effect. Read More

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September 2021

Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis.

PLoS One 2021 20;16(9):e0257584. Epub 2021 Sep 20.

Department of Pharmacy, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.

Background: Nausea and vomiting of pregnancy affects up to 80% of pregnant women, it typically occurs during the first trimester which is the most sensitive time for environmental exposures given organogenesis. Metoclopramide is an antiemetic drug used widely during NVP, but the findings of studies evaluating its safety of use in pregnancy is inconsistent. Therefore, we conducted a systematic review and meta-analysis to assess whether metoclopramide use during first trimester of pregnancy is associated with the risk of major congenital malformations. Read More

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September 2021

Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart.

PLoS One 2021 20;16(9):e0257280. Epub 2021 Sep 20.

Division of Gastroenterology, Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX, United States of America.

Ulcerative colitis and Crohn's disease are classified as chronic inflammatory bowel diseases (IBD) with known extraintestinal manifestations. The interplay between heart and gut in IBD has previously been noted, but the mechanisms remain elusive. Our objective was to identify microRNAs mediating molecular remodeling and resulting cardiac impairment in a rat model of colitis. Read More

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September 2021

E-learning and Web-based Tools for Psychosocial Interventions Addressing Neuropsychiatric Symptoms of Dementia during the COVID-19 pandemic: Quasi-Experimental Study Assessing Feasibility and Efficacy in Tokyo, Japan.

JMIR Med Educ 2021 Sep 19. Epub 2021 Sep 19.

Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, JP.

Background: Concern has been raised that the COVID-19 pandemic and consequent social distancing measures may increase neuropsychiatric symptoms in people with dementia. Thus, we developed and delivered an e-learning training course to professional caregivers on using a web-based tool for psychosocial interventions for people with dementia.

Objective: The objective of our study was to evaluate the feasibility and efficacy of an e-learning course in combination with a web-based tool in addressing neuropsychiatric symptoms of dementia. Read More

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September 2021

Altmetric Analysis of Skin of Color Articles: A Cross-Sectional Study.

J Cutan Med Surg 2021 Sep 20:12034754211045387. Epub 2021 Sep 20.

12295 Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.

Background: Publication and dissemination of peer-reviewed articles are essential for delivering up-to-date high-quality care to diverse populations. Online attention and publication trends for skin of color (SOC) articles have not been studied.

Objective: To investigate SOC article online attention and publication trends. Read More

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September 2021

Systematic administration and analysis of verbal fluency tasks: Preliminary evidence for reliable exploration of processes underlying task performance.

Appl Neuropsychol Adult 2021 Sep 20:1-13. Epub 2021 Sep 20.

Department of Psychology and Speech-Language Pathology, University of Turku, Turku, Finland.

Verbal fluency (VF) tasks are typically scored by the number of acceptable words generated within an allotted time (i.e., total score). Read More

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September 2021