452 results match your criteria included bpi

White Matter Hyperintensities after Five-Year Follow-Up and a Cross-Sectional FA Decrease in Bipolar I and Major Depressive Patients.

Neuropsychobiology 2021 Jun 15:1-12. Epub 2021 Jun 15.

Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Introduction: An increase in brain white matter hyperintensities (WMHs) and a decrease in white matter fractional anisotrophy (FA) have been detected in bipolar I (BPI), II (BPII), and major depressive disorder (MDD) patients. Their relationship, and differences in diagnostic groups are obscure. Longitudinal studies are rare. Read More

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A Phase II, Nonrandomized Open Trial Assessing Pain Efficacy with Radium-223 in Symptomatic Metastatic Castration-resistant Prostate Cancer.

Clin Genitourin Cancer 2021 Apr 19. Epub 2021 Apr 19.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Genitourinary Oncology Service, Weill Cornell Medicine, New York, NY.

Background: Prostate Cancer Working Group 3 and FDA guidelines recommend a standardized approach to pain assessment in preapproval trials. No prior trial has examined pain palliation of Radium-223 using standard dosing and contemporary PRO pain-assessment tools.

Methods: In this multicenter phase II trial, patients with Brief Pain Inventory (BPI) ≥3 were eligible for Radium-223 per its label. Read More

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Predictors of Persistent Postsurgical Pain Following Hysterectomy - A Prospective Cohort Study.

J Minim Invasive Gynecol 2021 May 30. Epub 2021 May 30.

Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON.

Study Objective: To determine socio-demographic, surgical, and psychological risk factors, including pain sensitivity, for persistent postsurgical pain (PPSP) following hysterectomy.

Design: A prospective cohort study.

Setting: Canadian academic medical center PATIENTS: Patients (n=200) who underwent hysterectomy (vaginal, laparoscopic, robotic or open) between 2013 and 2014. Read More

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Patchy Micelles with a Crystalline Core: Self-Assembly Concepts, Properties, and Applications.

Polymers (Basel) 2021 May 4;13(9). Epub 2021 May 4.

Macromolecular Chemistry II, University of Bayreuth, Universitätsstraße 30, 95440 Bayreuth, Germany.

Crystallization-driven self-assembly (CDSA) of block copolymers bearing one crystallizable block has emerged to be a powerful and highly relevant method for the production of one- and two-dimensional micellar assemblies with controlled length, shape, and corona chemistries. This gives access to a multitude of potential applications, from hierarchical self-assembly to complex superstructures, catalysis, sensing, nanomedicine, nanoelectronics, and surface functionalization. Related to these applications, patchy crystalline-core micelles, with their unique, nanometer-sized, alternating corona segmentation, are highly interesting, as this feature provides striking advantages concerning interfacial activity, functionalization, and confinement effects. Read More

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Duloxetine for the Treatment of Chronic Low Back Pain: A Systematic Review of Randomized Placebo-Controlled Trials.

Cureus 2021 May 22;13(5):e15169. Epub 2021 May 22.

Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, USA.

This systematic review determines the efficacy and safety of duloxetine for chronic low back pain (CLBP). We queried the PubMed, SCOPUS, and Ovid MEDLINE databases. All level I and II randomized controlled studies published in the English language investigating the efficacy of duloxetine for chronic low back pain were included. Read More

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Increased tibial tubercle-trochlear groove and patellar height indicate a higher risk of recurrent patellar dislocation following medial reefing.

Knee Surg Sports Traumatol Arthrosc 2021 May 25. Epub 2021 May 25.

Department of Traumatology and Reconstructive Surgery, BG Trauma Center Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.

Purpose: Identifying anatomical risk factors on recurrent dislocation after medial reefing is important for deciding surgical treatment. The present study aimed to retrospectively analyze the preoperative magnetic resonance imaging (MRI)-based parameters of patients treated with medial reefing and whether these parameters lead to a higher risk of recurrent dislocation.

Methods: Fifty-five patients (18. Read More

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Differences in stabilometric correlates of pain relief after wearing postural insoles for six weeks between chronic nociceptive and neuropathic foot pain. An open-label pilot study.

Neurophysiol Clin 2021 Jun 20;51(3):267-278. Epub 2021 May 20.

Univ Paris Est Creteil, EA4391, ENT, F-94010 Creteil, France; CH Sud-Seine-et-Marne, Pain Clinic (Centre d'Evaluation et Traitement de la Douleur), F-77140 Nemours, France.

Objective: The aim of this study was to determine if the use of postural insoles could result in a noticeable reduction in the foot pain intensity in patients with a chronic pain condition, either nociceptive (ankylosing spondylitis, AS) or neuropathic (small fiber neuropathy, SFN).

Method: In this open-label pilot study, patients were asked to wear postural insoles for a continuous period of 6 weeks. The primary endpoint was the mean daily pain intensity at foot mobilization measured using a visual analogue scale (VAS). Read More

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Trends in Brachial Plexus Surgery: Characterizing Contemporary Practices for Exploration of Supraclavicular Plexus.

Hand (N Y) 2021 May 21:15589447211014613. Epub 2021 May 21.

Washington University School of Medicine, St. Louis, MO, USA.

Background: There is variability in treatment strategies for patients with brachial plexus injury (BPI). We used qualitative research methods to better understand surgeons' rationale for treatment approaches. We hypothesized that distal nerve transfers would be preferred over exploration and nerve grafting of the brachial plexus. Read More

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Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population.

Transl Psychiatry 2021 May 20;11(1):301. Epub 2021 May 20.

Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.

The search for susceptibility genes underlying the heterogeneous bipolar disorder has been inconclusive, often with irreproducible results. There is a hope that narrowing the phenotypes will increase the power of genetic analysis. Early-onset bipolar disorder is thought to be a genetically homogeneous subtype with greater symptom severity. Read More

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A systematic review of patient-reported outcome measures used to assess postpartum pain using Consensus Based Standards for the Selection of Health Measurement Instruments (COSMIN) guidelines.

Br J Anaesth 2021 May 17. Epub 2021 May 17.

Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Background: We performed a systematic review using Consensus Based Standards for the Selection of Health Measurement Instruments (COSMIN) guidelines to identify the best available patient-reported outcome measure (PROM) of postpartum pain.

Methods: This review follows COSMIN guidelines. We searched four databases with no date limiters, for previously identified validated PROMs used to assess postpartum pain. Read More

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Do the successful revision surgery for humeral nonunion solve all the effects on health-related quality of life? A retrospective cohort study.

BMC Musculoskelet Disord 2021 May 5;22(1):414. Epub 2021 May 5.

Department of Orthopaedics and Trauma, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, No. 555, East Youyi Road, Shaanxi, 710000, Xi'an, China.

Background: The aim of this study is to evaluate the effects of successful revision operation on health quality of life(QoL) and functional outcome in humeral nonunion patients.

Methods: This retrospective study included 62 patients with humeral nonunion from Northwest China, who were admitted to the Department of Trauma Surgery, Honghui Hospital between March 2013 and September 2019. The following data were retrospectively evaluated: demographic data, clinical data, imaging findings, and treatment methods. Read More

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First report of eggplant mottled crinkle virus infecting eggplant in Greece.

Plant Dis 2021 May 2. Epub 2021 May 2.

Benaki Phytopathologiocal Institute, Plant Pathology, S. Delta 8, kifissia, Greece, 14561;

During winter 2020-2021, a severe virus-like disease outbreak was observed in eggplant ( L.) hybrids 'Monarca' (F1) and 'Angela' (F1) growing under protected conditions in Heraklion, Crete, Greece. In three greenhouses, the percentage of infected plants reached 100% leading to crop abandonment. Read More

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Development and validation of a short version of the French Hand Function Sort questionnaire in vocational rehabilitation.

Ann Phys Rehabil Med 2021 Apr 29:101533. Epub 2021 Apr 29.

Department of Medical Research, Clinique Romande de Réadaptation Suva, Sion, Switzerland; Division of Physical Medicine and Rehabilitation, Lausanne University Hospital, Lausanne, Switzerland.

Background: The Hand Function Sort (HFS) is a pictorial self-administered questionnaire with 62 items. It is a valid and reliable scale focused on the physical function of the upper limbs. It is used to predict the return to work. Read More

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Inequity in outcomes from New Zealand chronic pain services.

N Z Med J 2021 04 16;134(1533):11-20. Epub 2021 Apr 16.

Physiotherapist, Counties Manukau Health Chronic Pain Service, Counties Manukau District Health Board, Auckland.

Aim: To evaluate outcomes from chronic pain services in New Zealand based on patient ethnicity.

Method: Clinical and demographic data were obtained from 4,876 patients from the Electronic Persistent Pain Outcomes Collaboration (ePPOC) database, a database of standardised assessments from chronic pain services across New Zealand. Clinical questionnaires included the Brief Pain Inventory (BPI); Depression, Anxiety and Stress Scale - 21 items (DASS-21); Pain Catastrophising Scale (PCS); and the Pain Self-Efficacy Questionnaire (PSEQ). Read More

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Real world effectiveness of standard of care triple therapy versus two-drug combinations for treatment of people living with HIV.

PLoS One 2021 8;16(4):e0249515. Epub 2021 Apr 8.

Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background: Since 1996, the standard of care (SOC) therapy for HIV treatment has consisted of a backbone of two nucleoside analogue reverse transcriptase inhibitors (NRTI) paired with a third agent. Use of two-drug combinations (2DC) has been considered for selected patients to avoid toxicities associated with the use of NRTIs. This study aimed to compare the real-world outcomes of integrase strand transfer inhibitor (INSTI)-containing triple therapy (TT) to dolutegravir- (DTG) and/or boosted protease inhibitor (bPI)-based 2DC in a large Spanish cohort of HIV patients. Read More

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Comparison of the Clinical Outcomes between Short-term and Long-term Opioid Users with Noncancer Pain at Pain Clinics.

J Pharm Bioallied Sci 2020 Nov 5;12(Suppl 2):S728-S732. Epub 2020 Nov 5.

Department of Pharmacy Practice, Kulliyyah of Pharmacy, International Islamic University Malaysia (IIUM), Kuantan, Pahang, Malaysia.

Introduction: The clinical use of opioids for long-term for noncancer pain indications remains a controversy. More studies are needed for evidence-based guidelines in noncancer pain management involving opioids. The primary objective of this study was to investigate the clinical outcomes of the short-term and long-term opioid use among patients with noncancer pain. Read More

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November 2020

Efficacy of Exercise Rehabilitation Program in Relieving Oxaliplatin Induced Peripheral Neurotoxicity.

Asian Pac J Cancer Prev 2021 Mar 1;22(3):705-709. Epub 2021 Mar 1.

Departments of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, People's Republic of China.

Background: Peripheral neurotoxicity is common in patients with digestive malignancies receiving chemotherapy containing oxaliplatin, and there is still no effective drug to prevent or treat this complication.

Methods: Seventy-nine patients receiving chemotherapy containing oxaliplatin were included, and the relationship between chemotherapy regimens, cycles, and cumulative dose of oxaliplatin and peripheral neurotoxicity was analyzed. Patients were divided into two groups of control or intervention. Read More

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Associations of Coexisting Pain and Fatigue Severity with Physical Performance and Quality of Life among Middle-Aged and Older Individuals with Chronic Knee Pain: A randomized controlled trial.

Pain Med 2021 Mar 27. Epub 2021 Mar 27.

Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI.

Objective: To examine associations of combined pain and fatigue severity with physical performance and quality of life in people with chronic knee pain.

Design: Cross-sectional.

Setting: General community. Read More

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Effects of a physician- and pharmacist-managed clinic on pain management in cancer patients in China.

Basic Clin Pharmacol Toxicol 2021 Jul 4;129(1):36-43. Epub 2021 Apr 4.

Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.

In China, pharmacists have started to manage cancer pain at outpatient clinics. This retrospective study performed at a tertiary teaching hospital was aimed to evaluate the effects of a physician-pharmacist joint clinic for cancer pain management. The study was performed between December 2016 and August 2019 and included 113 outpatients with moderate to severe cancer-related pain. Read More

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Effectiveness of Electroacupuncture or Auricular Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among Cancer Survivors: The PEACE Randomized Clinical Trial.

JAMA Oncol 2021 May;7(5):720-727

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

Importance: The opioid crisis creates challenges for cancer pain management. Acupuncture confers clinical benefits for chronic nonmalignant pain, but its effectiveness in cancer survivors remains uncertain.

Objective: To determine the effectiveness of electroacupuncture or auricular acupuncture for chronic musculoskeletal pain in cancer survivors. Read More

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Measurement Properties of the Brief Pain Inventory-Short Form (BPI-SF) and Revised Short McGill Pain Questionnaire Version-2 (SF-MPQ-2) in Pain-related Musculoskeletal Conditions: A Systematic Review.

Clin J Pain 2021 Jun;37(6):454-474

Roth McFarlane Hand and Upper Limb Centre, St. Joseph's Hospital, London.

Objective: The objective of this study was to systematically locate, critically appraise, and summarize clinical measurement research addressing the use of Brief Pain Inventory-Short Form (BPI-SF) and Revised Short McGill Pain Questionnaire Version-2 (SF-MPQ-2) in pain-related musculoskeletal (MSK) conditions.

Materials And Methods: We systematically searched 4 databases (Medline, CINAHL, EMBASE, and SCOPUS) and screened articles to identify those reporting the psychometric properties (eg, validity, reliability) and interpretability (eg, minimal clinically important difference) of BPI-SF and SF-MPQ-2 as evaluated in pain-related MSK conditions. Independently, 2 reviewers extracted data and assessed the quality of evidence with a structured quality appraisal tool and the updated COSMIN guidelines. Read More

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Exploring factors associated with pain in hemodialysis patients: a multicenter cross-sectional study from Palestine.

BMC Nephrol 2021 03 17;22(1):96. Epub 2021 Mar 17.

Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, 44839, Nablus, Palestine.

Background: Chronic kidney disease (CKD) is a rising medical concern around the world. End-stage kidney disease (ESKD) is the last stage of CKD stages that necessitates renal replacement therapy (RRT), such as hemodialysis (HD), which seems to be the most commonly used type. However, patients on HD still suffer from high mortality and morbidity rates compared to those who receive a kidney transplant. Read More

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The Language of Pain: Is There a Relationship Between Metaphor Use and Adjustment to Chronic Pain?

Pain Med 2021 Mar 17. Epub 2021 Mar 17.

Discipline of Clinical Psychology, Graduate School of Health, University of Technology Sydney, Sydney, Australia.

Objective: Metaphor, frequently used in chronic pain, can function as a communicative tool, facilitating understanding and empathy from others. Previous research has demonstrated that specific linguistic markers exist for areas such as pain catastrophizing, mood, as well as diagnostic categories. The current study sought to examine potential associations between the types of pain metaphors used and diagnostic category, disability, and mood. Read More

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Diagnosis and management of adult BPI: Results of first 50 cases.

J Clin Orthop Trauma 2021 Jan 1;12(1):166-171. Epub 2020 Jul 1.

Department of Surgery, NSCB Government Medical College, Jabalpur, MP, 482003, India.

Introduction: Commonest cause of brachial plexus injury in adults is traction injury sustained in motorcycle accidents. This article reports the results of first 50 cases done in a tertiary referral center with a brief review of literature.

Material And Methods: First 50 patients (46 male; 4 female, age from 12 to 45 years) with post traumatic brachial plexus palsy were included. Read More

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January 2021

Association of citrus virus A to citrus impietratura disease symptoms.

Phytopathology 2021 Mar 11. Epub 2021 Mar 11.

Benaki Phytopathological Institute, 69064, 8, St. Delta str.,, Kifissia, Athens, Greece, 145 61;

Citrus impietratura disease (CID) is a graft transmissible, virus-like disease observed in old-line citrus trees; its characteristic symptom is the appearance of gum in the albedo of the affected fruits. To identify the causal agent of the disease, high throughput sequencing (HTS) was performed on symptomatic orange fruits. The analysis of the obtained data revealed in all samples, mixed infections of viroids commonly found in citrus trees together with the recently described citrus virus A (CiVA). Read More

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Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system: A randomized controlled trial.

Brain Stimul 2021 May-Jun;14(3):477-487. Epub 2021 Mar 5.

Department of Evidence-Based Medicine, Brazilian Cochrane Centre, Federal University of São Paulo, São Paulo, SP, Brazil; Department of Rheumatology, Santo Amaro University, São Paulo, SP, Brazil. Electronic address:

Background: Although evidence has indicated a positive effect of transcranial direct current stimulation (tDCS) on reducing pain, few studies have focused on the elderly population with knee osteoarthritis (KOA).

Objective: To evaluate whether tDCS reduces KOA pain in elderly individuals with a dysfunctional descending pain inhibitory system (DPIS).

Methods: In a double-blind trial, individuals ≥ 60 years with KOA pain and a dysfunctional DPIS, we randomly assigned patients to receive 15 daily sessions of 2 mA tDCS over the primary motor cortex (anode) and contralateral supraorbital area (cathode) (M1-SO) for 20 min or sham tDCS. Read More

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Preoperative sleep quality and adverse pain outcomes after total hip arthroplasty.

Eur J Pain 2021 Mar 8. Epub 2021 Mar 8.

Clinical Memory Research Unit, Faculty of Medicine, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.

Background: Sleep disturbance is thought to aggravate acute postoperative pain. The influence of preoperative sleep problems on pain control in the long-term and development of chronic postsurgical pain is largely unknown.

Methods: This prospective, observational study aimed to examine the links between preoperative sleep disturbance (Pittsburgh Sleep Quality Index, PSQI) and pain severity (Brief Pain Inventory, BPI) 6 months postoperative (primary outcome), objective measures of pain and postoperative pain control variables (secondary outcomes). Read More

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Effect of perioperative pain neuroscience education in patients with post-mastectomy persistent pain: a retrospective, propensity score-matched study.

Support Care Cancer 2021 Mar 6. Epub 2021 Mar 6.

Department of Breast Surgery, Breast Care Sensyu Clinic, Osaka, Japan.

Purpose: Central sensitization (CS)-related symptoms and pain catastrophizing contribute to persistent post-mastectomy pain (PPMP). Pain neuroscience education (PNE) is effective in reducing CS-related symptoms and pain catastrophizing in patients with chronic pain. However, to date, no intervention study of PNE has been conducted to patients with PPMP. Read More

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Effect of Organic and Conventional Production Methods on Fruit Yield and Nutritional Quality Parameters in Three Traditional Cretan Grape Varieties: Results from a Farm Survey.

Foods 2021 Feb 22;10(2). Epub 2021 Feb 22.

Nafferton Ecological Farming Group, School of Agriculture, Food and Rural Development, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

The antioxidants found in grapes and wine have been linked to health benefits in humans, but may be affected by agronomic parameters, grape type/variety, and processing. Here, we report results of a farm survey which investigated the effects of production system (organic vs. conventional) and grape variety on fruit yield, total antioxidant activity/capacity (TAA, assessed by the Trolox Equivalent Antioxidant Capacity (TEAC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays), and total concentrations of total phenolics (TPC) and anthocyanins (TAC) in grapes of one red (Kotsifali) and two white (Villana and/or Vidiano) traditional Cretan grape varieties. Read More

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February 2021

Evaluating psychometric properties of the Short Form Brief Pain Inventory Sinhala Version (SF BPI-Sin) among Sinhala speaking patients with cancer pain in Sri Lanka.

BMC Psychol 2021 Feb 23;9(1):34. Epub 2021 Feb 23.

Department of Community Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

Background: Pain is one of the most common and unpleasant symptoms of patients with cancer. The Short Form Brief Pain Inventory (SF-BPI), has been psychometrically validated in several languages and widely used globally. Availability of a validated pain tool in Sinhala is a current requirement enabling the use among the majority of Sinhala-speaking cancer patients in Sri Lanka. Read More

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February 2021