539 results match your criteria incipient approach

Resolving species boundaries in a recent radiation with the Angiosperms353 probe set: the Lomatium packardiae/L. anomalum clade of the L. triternatum (Apiaceae) complex.

Am J Bot 2021 Jun 8. Epub 2021 Jun 8.

Department of Biological Sciences, Boise State University, Boise, ID, 83725, USA.

Premise: Speciation not associated with morphological shifts is challenging to detect unless molecular data are employed. Using Sanger-sequencing approaches, the Lomatium packardiae/L. anomalum subcomplex within the larger Lomatium triternatum complex could not be resolved. Read More

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Patient-centeredness in Physiotherapy - A literature mapping review.

Physiother Theory Pract 2021 Jun 7:1-13. Epub 2021 Jun 7.

Department for People and Technology, Centre for Health Promotion Research, Roskilde University Roskilde, Denmark.

: Research on patient-centeredness within physiotherapy points to a need for clarification about what the concept entails in science and practice and how research positions itself within health care. Thus, the aim is to systematically map the characteristics of research on patient-centeredness in physiotherapy and critically discuss the dominant understandings within. : A systematic research mapping was carried out, based on searches in leading bibliographic databases. Read More

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[Mental Health in Primary Care: perspectives of professionals of the Family Health Strategy in Northeastern Brazil].

Cien Saude Colet 2021 May;26(5):1739-1748

Laboratório de Avaliação e Pesquisa Qualitativa em Saúde, Faculdade de Medicina, Universidade Federal do Ceará. Fortaleza CE Brasil.

The Family Health Strategy (FHS) of the Unified Health System (SUS) is the revised model that governs health care and the work processes adopted in Brazil. This article analyzes the perceptions of FHS professionals regarding mental health and the care provided in a health center in a Basic Care Unit in the Brazilian Northeast. It involved qualitative research aligned with a critical interpretative approach conducted through interviews, straightforward observation and documentary analysis that led to a series of considerations organized into two main groups: a) "Mental Health" from the perspective of professionals of the FHS; and b) Care in "Mental Health" in the context of practices of primary care. Read More

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Evolution of protective symbiosis in palaemonid shrimps (Decapoda: Caridea) with emphases on host spectrum and morphological adaptations.

Mol Phylogenet Evol 2021 May 11;162:107201. Epub 2021 May 11.

Simon F.S. Li Marine Science Laboratory, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address:

Palaemonidae is the most speciose caridean shrimp family, with its huge biodiversity partially generated via symbiosis with various marine invertebrates. Previous studies have provided insights into the evolution of protective symbiosis in this family with evidence for frequent inter-phyla host switches, but the comprehensiveness of evolutionary pathways is hampered by the resolution of the previous phylogenetic trees as well as the taxon coverage. Furthermore, several critical issues related to the evolution of a symbiotic lifestyle, including the change in host spectrum and corresponding morphological adaptations, remain largely unresolved. Read More

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An Automated Data Fusion-Based Gear Faults Classification Framework in Rotating Machines.

Sensors (Basel) 2021 Apr 23;21(9). Epub 2021 Apr 23.

Department of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester M13 9PL, UK.

The feasibility and usefulness of frequency domain fusion of data from multiple vibration sensors installed on typical industrial rotating machines, based on coherent composite spectrum (CCS) as well as poly-coherent composite spectrum (pCCS) techniques, have been well-iterated by earlier studies. However, all previous endeavours have been limited to rotor faults, thereby raising questions about the proficiency of the approach for classifying faults related to other critical rotating machine components such as gearboxes. Besides the restriction in scope of the founding CCS and pCCS studies on rotor-related faults, their diagnosis approach was manually implemented, which could be unrealistic when faced with routine condition monitoring of multi-component industrial rotating machines, which often entails high-frequency sampling at multiple locations. Read More

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Intraocular lens subluxation and decompensated pseudoexfoliation glaucoma in a patient's only reading eye May consultation #1.

Rupert Menapace

J Cataract Refract Surg 2021 May;47(5):678

An 89-year-old man had cataract surgery in 2005 in both eyes. At that time, he already had glaucoma that was well regulated with topical therapy and drusen maculopathy with incipient areal atrophy. Fifteen years later, the patient presented with a decrease in visual acuity of his only reading eye, his right eye. Read More

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Highly Active and Stable Palladium Catalysts on Novel Ceria-Alumina Supports for Efficient Oxidation of Carbon Monoxide and Hydrocarbons.

Environ Sci Technol 2021 Jun 19;55(11):7624-7633. Epub 2021 Apr 19.

Department of Civil, Environmental, and Construction Engineering, Catalysis Cluster for Renewable Energy and Chemical Transformations (REACT), NanoScience Technology Center (NSTC), University of Central Florida, Orlando, Florida 32816, United States.

Precious metal catalysts with superior low-temperature activity and excellent thermal stability are highly needed in environmental catalysis field. In this work, a novel two-step incipient wetness impregnation (T-IWI) method was developed for the fabrication of a unique and highly stable CeO/AlO support (CA-T). Pd anchored on CA-T exhibited a much higher low-temperature catalytic activity and superior thermal stability in carbon monoxide (CO) and hydrocarbon (HC) oxidations, compared to Pd anchored on conventional CeO/AlO (CA), which was prepared by a one-step IWI method. Read More

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[Peripheral nerve reconstruction - diagnostics as a basis for decision-making: report of the Consensus Workshop at the 35th Meeting of the DAM].

Handchir Mikrochir Plast Chir 2021 Apr 15;53(2):168-174. Epub 2021 Apr 15.

Medizinische Universitat Wien Department of Surgery, Division of Plastic and Reconstructive Surgery.

In the early stage of nerve lesions, the clinical differentiation between neurapraxia, axonotmesis and neurotmesis often presents a big challenge. Especially in the early stage, however, it is crucial to correctly classify the type of damage because this is what essentially determines the therapeutic concept, in particular the surgical approach and, therefore, the prognosis. A precise diagnosis not only requires detailed clinical assessment and medical history taking, but also the use of additional electrophysiological (functional) and/or imaging examinations. Read More

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Morphological and ecological responses of a managed coastal sand dune to experimental notches.

Sci Total Environ 2021 Aug 5;782:146813. Epub 2021 Apr 5.

Office National des Forêts, 75570 CEDEX 12 Paris, France. Electronic address:

In northern Europe, coastal dune remobilization by restoring natural processes is considered by some to maintain the coastal dune in chronically eroding sectors by migrating landward and to restore dune ecology. In wet climatic contexts, this nature-based solution has been shown to induce an increase in both sand bare areas and vegetation diversity. However, it has never been tested in the coastal dunes of southern Europe with a drier climate and, thus, more stressful conditions, where disturbance may inversely decrease vegetation diversity. Read More

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Fault Prediction and Early-Detection in Large PV Power Plants Based on Self-Organizing Maps.

Sensors (Basel) 2021 Mar 1;21(5). Epub 2021 Mar 1.

Department of Energy, Systems, Territory and Construction Engineering (DESTEC), University of Pisa, 56122 Pisa, Italy.

In this paper, a novel and flexible solution for fault prediction based on data collected from Supervisory Control and Data Acquisition (SCADA) system is presented. Generic fault/status prediction is offered by means of a data driven approach based on a self-organizing map (SOM) and the definition of an original Key Performance Indicator (KPI). The model has been assessed on a park of three photovoltaic (PV) plants with installed capacity up to 10 MW, and on more than sixty inverter modules of three different technology brands. Read More

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Incipient resistance to an effective pesticide results from genetic adaptation and the canalization of gene expression.

Evol Appl 2021 Mar 14;14(3):847-859. Epub 2020 Dec 14.

Department of Biological Sciences Purdue University West Lafayette IN USA.

The resistance of pest species to chemical controls has vast ecological, economic, and societal costs. In most cases, resistance is only detected after spreading throughout an entire population. Detecting resistance in its incipient stages, by comparison, provides time to implement preventative strategies. Read More

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Clinical impact of a sub-epidermal moisture scanner: what is the real-world use?

J Wound Care 2021 Mar;30(3):198-208

St. Helens Medical Centre, Isle of Wight, UK.

Objective: The presence of sub-epidermal moisture (SEM) over a bony prominence is indicative of incipient pressure ulcer (pressure injury/decubitus/bedsore) (PU). Early identification of patients at increased risk of PU can prompt interventions that reduce the incidence and severity of hospital (or community)-acquired PUs (HAPUs). This study evaluated the clinical utility of a SEM Scanner device in HAPU management. Read More

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Genomic studies of milk-related traits in water buffalo (Bubalus bubalis) based on single-step genomic best linear unbiased prediction and random regression models.

J Dairy Sci 2021 May 6;104(5):5768-5793. Epub 2021 Mar 6.

Department of Animal Sciences, Purdue University, West Lafayette, IN 47907. Electronic address:

Genomic selection has been widely implemented in many livestock breeding programs, but it remains incipient in buffalo. Therefore, this study aimed to (1) estimate variance components incorporating genomic information in Murrah buffalo; (2) evaluate the performance of genomic prediction for milk-related traits using single- and multitrait random regression models (RRM) and the single-step genomic best linear unbiased prediction approach; and (3) estimate longitudinal SNP effects and candidate genes potentially associated with time-dependent variation in milk, fat, and protein yields, as well as somatic cell score (SCS) in multiple parities. The data used to estimate the genetic parameters consisted of a total of 323,140 test-day records. Read More

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Impregnating Subnanometer Metallic Nanocatalysts into Self-Pillared Zeolite Nanosheets.

J Am Chem Soc 2021 May 4;143(18):6905-6914. Epub 2021 Mar 4.

State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, People's Republic of China.

Impregnation is the most commonly used approach to prepare supported metal catalysts in industry. However, this method suffers from the formation of large metal particles with uneven dispersion, poor thermal stability, and thus unsatisfied catalytic performance. Here, we demonstrate that the self-pillared zeolite (silicalite-1 and ZSM-5) nanosheets with larger surface area and abundant Si-OH groups are ideal supports to immobilize ultrasmall monometallic (e. Read More

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Alterations in Dynamic Functional Connectivity in Individuals With Subjective Cognitive Decline.

Front Aging Neurosci 2021 3;13:646017. Epub 2021 Feb 3.

Department of Radiology, Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China.

To investigate the dynamic functional connectivity (DFC) and static parameters of graph theory in individuals with subjective cognitive decline (SCD) and the associations of DFC and topological properties with cognitive performance. Thirty-three control subjects and 32 SCD individuals were enrolled in this study, and neuropsychological evaluations and resting-state functional magnetic resonance imaging scanning were performed. Thirty-three components were selected by group independent component analysis to construct 7 functional networks. Read More

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February 2021

Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-opening to halohydrins.

Org Biomol Chem 2021 03;19(9):2038-2043

University of Vienna - Department of Pharmaceutical Chemistry, Althanstrasse, 14, 1090, Vienna, Austria. and University of Turin - Department of Chemistry, Via P. Giuria 7, 10125, Turin, Italy.

The intrinsic degradative α-elimination of Li carbenoids somehow complicates their use in synthesis as C1-synthons. Nevertheless, we herein report how boosting such an α-elimination is a straightforward strategy for accomplishing controlled ring-opening of epoxides to furnish the corresponding β-halohydrins. Crucial for the development of the method is the use of the eco-friendly solvent 2-MeTHF, which forces the degradation of the incipient monohalolithium, due to the very limited stabilizing effect of this solvent on the chemical integrity of the carbenoid. Read More

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Incipient fault diagnosis of bearings based on parameter-optimized VMD and envelope spectrum weighted kurtosis index with a new sensitivity assessment threshold.

ISA Trans 2021 Aug 28;114:413-433. Epub 2020 Dec 28.

Faculty of Mechanical Engineering, University of Tabriz, Tabriz, 51666-16471, Iran. Electronic address:

Due to difficulties in identifying localized and incipient bearing faults, most proposed fault diagnosis methods focus on detecting these faults. However, it is not clear to what extent of fault severity the proposed methods are capable of detecting. In other words, the crucial issue remains in the literature as to what is the criteria for defining an incipient defect for the proposed methods. Read More

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An Entropic Approach to Estimating the Instability Criterion of People in Floodwaters.

Entropy (Basel) 2021 Jan 6;23(1). Epub 2021 Jan 6.

Beijing Key Laboratory of Urban Hydrological Cycle and Sponge City Technology, College of Water Sciences, Beijing Normal University, Beijing 100875, China.

People are always susceptible to a loss of stability in urban floodwaters that leads to serious casualties. Thus, the safety criterion for the instability of people in floodwaters must be determined. In this study, the hydrodynamic criterion of the instability of people in floodwaters in terms of the incipient velocity and water depth is derived using the probability method based on Shannon entropy theory. Read More

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January 2021

Unilateral Isolated Paucisymptomatic Optic Disc Edema.

J Neuroophthalmol 2020 Dec 22;Publish Ahead of Print. Epub 2020 Dec 22.

Departments of Ophthalmology (EH, RAS, JHP, MD, NJN, VB), Pediatrics (JHP), Neurology (NJN, VB), and Neurological Surgery (NJN), Emory University School of Medicine, Atlanta, Georgia.

Background: Unilateral isolated optic disc edema (UIODE) represents a challenging clinical presentation that frequently precipitates an extensive diagnostic work-up. Patients without an apparent diagnosis despite appropriate investigations are often categorized as having "papillophlebitis," an entity that is poorly defined in the existing literature. Our aim was to describe the characteristics of a series of patients with paucisymptomatic UIODE, determine the optimal diagnostic approach to such cases, and clarify the clinical features of presumed papillophlebitis. Read More

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December 2020

Maintenance of Species Differences in Closely Related Tetraploid Parasitic (Orobanchaceae) on an Isolated Island.

Plant Commun 2020 Nov 1;1(6):100105. Epub 2020 Sep 1.

University of Edinburgh, School of Biological Sciences, Institute of Evolutionary Biology, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.

Polyploidy is pervasive in angiosperm evolution and plays important roles in adaptation and speciation. However, polyploid groups are understudied due to complex sequence homology, challenging genome assembly, and taxonomic complexity. Here, we study adaptive divergence in taxonomically complex eyebrights (), where recent divergence, phenotypic plasticity, and hybridization blur species boundaries. Read More

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November 2020

Exploring a Structural Basis for Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration Via Deep Learning.

Transl Vis Sci Technol 2020 12 15;9(2):62. Epub 2020 Dec 15.

Department of Ophthalmology and Visual Sciences, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Purpose: Delayed rod-mediated dark adaptation (RMDA) is a functional biomarker for incipient age-related macular degeneration (AMD). We used anatomically restricted spectral domain optical coherence tomography (SD-OCT) imaging data to localize de novo imaging features associated with and to test hypotheses about delayed RMDA.

Methods: Rod intercept time (RIT) was measured in participants with and without AMD at 5 degrees from the fovea, and macular SD-OCT images were obtained. Read More

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December 2020

Using the Maximal Entropy Modeling Approach to Analyze the Evolution of Sedentary Agricultural Societies in Northeast China.

Entropy (Basel) 2020 Mar 9;22(3). Epub 2020 Mar 9.

Department of Asian Studies, the Hebrew University of Jerusalem, Jerusalem 9190501, Israel.

The emergence of agriculture and the evolution of sedentary societies are among the most important processes in human history. However, although archeologists and social scientists have long been studying these processes, our understanding of them is still limited. This article focuses on the Fuxin area in present-day Liaoning province in Northeast China. Read More

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Blind source separation with integrated photonics and reduced dimensional statistics.

Opt Lett 2020 Dec;45(23):6494-6497

Microwave communications have witnessed an incipient proliferation of multi-antenna and opportunistic technologies in the wake of an ever-growing demand for spectrum resources, while facing increasingly difficult network management over widespread channel interference and heterogeneous wireless broadcasting. Radio frequency (RF) blind source separation (BSS) is a powerful technique for demixing mixtures of unknown signals with minimal assumptions, but relies on frequency dependent RF electronics and prior knowledge of the target frequency band. We propose photonic BSS with unparalleled frequency agility supported by the tremendous bandwidths of photonic channels and devices. Read More

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December 2020

Investigating the impact of captivity and domestication on limb bone cortical morphology: an experimental approach using a wild boar model.

Sci Rep 2020 11 4;10(1):19070. Epub 2020 Nov 4.

Archéozoologie, Archéobotanique: Sociétés, Pratiques et Environnements, UMR 7209, Muséum national d'Histoire naturelle, CNRS, Paris, France.

The lack of bone morphological markers associated with the human control of wild animals has prevented the documentation of incipient animal domestication in archaeology. Here, we assess whether direct environmental changes (i.e. Read More

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November 2020

Perceived barriers and facilitators to chronic kidney disease care among patients in Singapore: a qualitative study.

BMJ Open 2020 10 16;10(10):e041788. Epub 2020 Oct 16.

Program in Health Services & Systems Research, Duke-NUS Medical School, Singapore

Objective: To outline the facilitators and barriers to patients' self-management of predialysis chronic kidney disease (CKD).

Design: Qualitative.

Setting: Three polyclinics in a public primary care institution in Singapore. Read More

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October 2020

Early Detection of Incipient Retinal Pigment Epithelium Atrophy Overlying Drusen with Fundus Autofluorescence . Spectral Domain Optical Coherence Tomography.

J Ophthalmol 2020 16;2020:9457457. Epub 2020 Sep 16.

Institut de la Màcula Centro Médico Teknon, Barcelona, Spain.

Purpose: This study aims to find out which tool, fundus autofluorescence (FAF) or spectral domain optical coherence tomography (SD-OCT), is more sensitive in detecting retinal pigment epithelium (RPE) demise overlying drusen and can, therefore, help predict geographic atrophy (GA) appearance in Age-Related Macular Degeneration (AMD).

Methods: A single-site, retrospective, observational, longitudinal study was conducted. Patients with intermediate AMD (iAMD) (large (>125 m) or intermediate (63-125 m) drusen with hyper/hypopigmentation) with a minimum follow-up of 18 months were included. Read More

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September 2020

The effect of hybridization on transposable element accumulation in an undomesticated fungal species.

Elife 2020 09 21;9. Epub 2020 Sep 21.

Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Canada.

Transposable elements (TEs) are mobile genetic elements that can profoundly impact the evolution of genomes and species. A long-standing hypothesis suggests that hybridization could deregulate TEs and trigger their accumulation, although it received mixed support from studies mostly in plants and animals. Here, we tested this hypothesis in fungi using incipient species of the undomesticated yeast . Read More

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September 2020

From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimer's Disease.

Curr Neuropharmacol 2021 ;19(6):832-867

Departamento de Quimica Organica y Fisicoquimica, Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile, Olivos 1007, Independencia, Santiago, Chile.

Alzheimer's disease (AD) is a chronic, progressive, and fatal neurodegenerative disorder affecting cognition, behavior, and function, being one of the most common causes of mental deterioration in elderly people. Once thought as being just developed because of β amyloid depositions or neurofibrillary Tau tangles, during the last decades, numerous AD-related targets have been established, the multifactorial nature of AD became evident. In this context, the one drug-one target paradigm has resulted in being inefficient in facing AD and other disorders with complex etiology, opening the field for the emergence of the multitarget approach. Read More

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January 2021

Morphological evidence for early dog domestication in the European Pleistocene: New evidence from a randomization approach to group differences.

Anat Rec (Hoboken) 2021 01 31;304(1):42-62. Epub 2020 Aug 31.

Operational Direction "Earth and History of Life", Royal Belgian Institute of Natural Sciences, Brussels, Belgium.

The antiquity of the wolf/dog domestication has been recently pushed back in time from the Late Upper Paleolithic (~14,000 years ago) to the Early Upper Paleolithic (EUP; ~36,000 years ago). Some authors questioned this early dog domestication claiming that the putative (EUP) Paleolithic dogs fall within the morphological range of recent wolves. In this study, we reanalyzed a data set of large canid skulls using unbalanced- and balanced-randomized discriminant analyses to assess whether the putative Paleolithic dogs are morphologically unique or whether they represent a subsample of the wolf morpho-population. Read More

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January 2021

Predicting Early Warning Signs of Psychotic Relapse From Passive Sensing Data: An Approach Using Encoder-Decoder Neural Networks.

JMIR Mhealth Uhealth 2020 08 31;8(8):e19962. Epub 2020 Aug 31.

Cornell Tech, New York, NY, United States.

Background: Schizophrenia spectrum disorders (SSDs) are chronic conditions, but the severity of symptomatic experiences and functional impairments vacillate over the course of illness. Developing unobtrusive remote monitoring systems to detect early warning signs of impending symptomatic relapses would allow clinicians to intervene before the patient's condition worsens.

Objective: In this study, we aim to create the first models, exclusively using passive sensing data from a smartphone, to predict behavioral anomalies that could indicate early warning signs of a psychotic relapse. Read More

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