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Electromagnetic muscle stimulation: A retrospective study of patient experience.

J Cosmet Dermatol 2021 Sep 24. Epub 2021 Sep 24.

Allergan Aesthetics, An AbbVie Company, Pleasanton, CA, USA.

Background: Electromagnetic muscle stimulation (EMMS) is a non-invasive body contouring technology for strengthening, firming, and toning the abdomen, buttocks, and thighs that is associated with high patient satisfaction.

Aims: To gain a greater understanding of factors contributing to patient satisfaction with EMMS.

Methods: This was a retrospective, non-comparative study of patient information and questionnaires regarding EMMS treatments to abdomen and/or buttocks collected July 1 to December 1, 2019 from clinical practices in the United States. Read More

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September 2021

Impact of Catheter Choice on Procedural Success of Minimally Invasive Surfactant Therapy.

Am J Perinatol 2021 Sep 24. Epub 2021 Sep 24.

Children's Hospital, London Health Science Centre, Department of Pediatrics, Western University, London, Ontario, Canada.

Objective:  Surfactant delivery via a thin endotracheal catheter during spontaneous breathing; a technique called minimally invasive surfactant therapy (MIST) is an alternative to intubation and surfactant administration. Procedural details among different centers vary, with marked differences in the choice of catheter to instill surfactant. Studies report use of feeding catheters, multiaccess suction catheters, vascular catheters, and more recently custom-built catheters for this purpose. Read More

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September 2021

Success Rate and Perioperative Complications of Lumbosacral Extradural Anaesthesia in Dogs Undergoing Total Hip Replacement: A Double-Centre Retrospective Study.

Vet Comp Orthop Traumatol 2021 Sep 24. Epub 2021 Sep 24.

Dick White Referrals, Six Mile Bottom, Cambridgeshire, United Kingdom.

Objective:  The aim of this study was to retrospectively evaluate the success rate and perioperative complications of lumbosacral extradural anaesthesia in dogs undergoing total hip replacement.

Study Design:  Records of dogs undergoing total hip replacement in which lumbosacral extradural anaesthesia with 0.5% levo- or bupivacaine combined with either morphine or buprenorphine were retrieved. Read More

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September 2021

Detecting Injury Risk Factors with Algorithmic Models in Elite Women's Pathway Cricket.

Int J Sports Med 2021 Sep 24. Epub 2021 Sep 24.

Department for Health, University of Bath, Bath, United Kingdom of Great Britain and Northern Ireland.

This exploratory retrospective cohort analysis aimed to explore how algorithmic models may be able to identify important risk factors that may otherwise not have been apparent. Their association with injury was then assessed with more conventional data models. Participants were players registered on the England and Wales Cricket Board women's international development pathway (n=17) from April 2018 to August 2019 aged between 14-23 years (mean 18. Read More

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September 2021

Variations in Nuss Procedure Operative Techniques and Complications: A Retrospective Review.

Eur J Pediatr Surg 2021 Sep 24. Epub 2021 Sep 24.

Division of Pediatric Surgery, Texas Children's Hospital, Houston, Texas, United States.

Introduction:  The Nuss procedure is the most common and preferred operative correction of pectus excavatum. Surgeon preference and patient factors can result in variations in Nuss procedure technique. We hypothesize that certain techniques are associated with increased risk of complications. Read More

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September 2021

Reticulocyte Count: The Forgotten Factor in Transfusion Decisions for Extremely Low Birth Weight Infants.

Am J Perinatol 2021 Sep 24. Epub 2021 Sep 24.

Pediatrics/Neonatology, CHOP Newborn services at Virtua, Voorhees, United States.

Background: Extremely low birth weight (ELBW) infants often receive transfusions of packed red blood cells. Long-term outcomes of infants treated with liberal versus restricted transfusion criteria have been evaluated with conflicting results. Clinicians incorporate a reticulocyte count (RC) in their transfusion decisions. Read More

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September 2021

Antimicrobial Stewardship in Bronchiolitis: A Retrospective Cohort Study of Three PICUs in Canada.

Pediatr Crit Care Med 2021 Sep 27. Epub 2021 Sep 27.

Department of Pediatric Critical Care, Critical Care Center, King Fahad Medical City, Riyadh, Saudi Arabia. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada. Division of Pediatric Critical Care, Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Department of Pathology and Lab Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada. Division of Pediatric Critical Care, Department of Pediatrics, McGill University, Montreal, QC, Canada. Division of Pediatric Infectious Diseases, Department of Pediatrics, McGill University, Montreal, QC, Canada. Department of Microbiology, Infectious Diseases and Immunology, Université de Montréal, Montreal, QC, Canada. Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada. Division of Pediatric Critical Care, Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada. Research Institute of the McGill University Health Centre, Montreal, QC, Canada. Division of Pediatric Critical Care, Department of Pediatrics, Centre Hospitalier Universitaire Sainte Justine, Montreal, QC, Canada.

Objectives: To determine the association between the implementation of an antimicrobial stewardship program at a local PICU and to determine the association between the presence of an antimicrobial stewardship programs and antimicrobial use across three Canadian PICUs, among critically ill children with bronchiolitis.

Design: A multicenter retrospective cohort study.

Setting: Three Canadian PICUs over two winter seasons. Read More

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September 2021

Primary Septic Arthritis in Children Demonstrates Presumed and Confirmed Varieties Which Require Age-specific Evaluation and Treatment Strategies.

J Pediatr Orthop 2021 Sep 27. Epub 2021 Sep 27.

Children's Health System of Texas Department of Orthopedics, Texas Scottish Rite Hospital for Children Department of Orthopedics and Pediatrics, University of Texas Southwestern, Dallas, TX.

Background: There is uncertainty involved in the evaluation and treatment of children suspected to have septic arthritis particularly when no causative pathogen is confirmed. This study evaluates children with primary septic arthritis to refine the processes of evaluation and treatment and improve the rate of pathogen confirmation.

Methods: Children suspected to have septic arthritis from 2009 to 2019 were retrospectively studied. Read More

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September 2021

Patterns of Mandibular Fractures in South Australia: Epidemiology, Treatment, and Clinical Outcomes.

J Craniofac Surg 2021 Sep 24. Epub 2021 Sep 24.

Australian Craniofacial Unit, Royal Adelaide Hospital, Women and Children's Hospital, University of Adelaide, Adelaide School of Medicine, University of Notre Dame, Sydney, Australia.

Introduction: The mandible is one of the most common facial bones to be injured with great clinical variability across countries caused by assaults, road traffic accidents, and falls.

Methods: A retrospective review was conducted for adult mandibular fractures from January 2012 to January 2017 at the Royal Adelaide Hospital, Adelaide. Our aim was to describe epidemiological trends of mandibular fractures, differences for sex and age, and clinical outcomes. Read More

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September 2021

Multidisciplinary Care for Refractory Pediatric Functional Abdominal Pain Decreases Emergency and Inpatient Utilization.

J Pediatr Gastroenterol Nutr 2021 Sep 15. Epub 2021 Sep 15.

Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine/Texas Children's Hospital Department of Anesthesia, Baylor College of Medicine/Texas Children's Hospital Stanford Medicine Department of Anesthesia, Perioperative and Pain Medicine, Palo Alto, California Children's Nutrition Research Center, United States Department of Agriculture, Houston, TX.

Abstract: Children with refractory functional abdominal pain (FAP) experience functional disability and may utilize emergency department (ED) and/or inpatient services. Whether multidisciplinary programs which help care for children with refractory FAP affect acute healthcare utilization is unknown. A retrospective chart review of children initially evaluated by the outpatient Multidisciplinary Abdominal Pain Program (MAPP) from October 2016 to May 2019 was completed. Read More

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September 2021

Effect of Added Free Water to Enteral Tube Feeds in Children Receiving Commercial Blends.

J Pediatr Gastroenterol Nutr 2021 Sep 22. Epub 2021 Sep 22.

Aerodigestive Center, Center for Motility and Functional Gastrointestinal Disorders, Division of Gastroenterology, Hepatology & Nutrition, Boston Children's Hospital, Boston, MA.

Objectives: To determine the impact of free water administration on clinical outcomes in medically complex patients, based on the hypothesis that patients receiving more thin liquids have worse outcomes related to increased risk of gastroesophageal reflux.

Methods: This was a retrospective chart review of children initiated on commercial blenderized tube feedings from 2010 to 2019. The percentage of gastrostomy intake that was a thin liquid was determined, with thin liquids including free water or thin formula based on the International Dysphagia Diet Stardardization Initiative (IDDSI) framework. Read More

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September 2021

Venoarterial Extracorporeal Membrane Oxygenation in Severe Drug Intoxication: A Retrospective Comparison of Survivors and Nonsurvivors.

ASAIO J 2021 Sep 20. Epub 2021 Sep 20.

From the Department of Intensive Care, CHU Lille, Lille, France University of Lille, Inserm U1167, Institut Pasteur de Lille, Lille, France Department of Cardiovascular Surgery, CHU Lille, Lille, France Cardiovascular Intensive Care Unit, CHU Lille, Lille, France University of Lille, Inserm U1011, Institut Pasteur de Lille, EGID, Lille, France Emergency Department and SAMU, CHU Lille, Lille, France University of Lille, Inserm U1285, CNRS UMR 8576, Lille, France.

Selecting patients most likely to benefit from venoarterial extracorporeal membrane oxygenation (V-A ECMO) to treat refractory drug-induced cardiovascular shock remains a difficult challenge for physicians. This study reported short-term survival outcomes and factors associated with mortality in V-A ECMO-treated patients for poisoning. Twenty-two patients placed on V-A ECMO after drug intoxication from January 2014 to December 2020 were retrospectively analyzed. Read More

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September 2021

Is Foot Drop an Underreported Sequela of Extracorporeal Membrane Oxygenation?

ASAIO J 2021 Sep 20. Epub 2021 Sep 20.

From the Center for Advanced Heart Failure, Memorial Hermann Hospital-Texas Medical Center, Houston, Texas Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas Health Science Center at Houston, Houston, Texas Rehabilitation Services, Memorial Hermann Hospital-Texas Medical Center, Houston, Texas.

Foot drop in the absence of limb ischemia is a chronic complication in peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) survivors; however, there is little published regarding the incidence and functional outcomes of this condition. Common peroneal nerve is the most common cause of foot drop, a condition that leads to significant debility and requires extensive physical therapy and rehabilitation, thereby affecting the patient's quality of life. We completed a retrospective review of 153 patients who received femoral cannulation for V-A ECMO support for greater than 1 hour. Read More

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September 2021

Cytomegalovirus Donor Seropositivity Negatively Affects Survival After Heart Transplantation.

Transplantation 2021 Sep 23. Epub 2021 Sep 23.

University of Erlangen-Nuremberg, Cardiac Surgery, Erlangen, Germany United Network for Organ Sharing, Richmond, VA, USA Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California, USA University Luebeck, Cardiac Surgery, Luebeck, Germany.

Objectives: Prior studies have shown that cytomegalovirus(CMV) infection is a risk factor for the development of cardiac allograft vasculopathy(CAV) and is associated with reduced long-term survival after heart transplantation. The aim of this ISHLT Transplant Registry study was to compare post-transplant survival in different CMV donor:recipient serologic combinations.

Methods: We performed a retrospective cohort study, using the ISHLT Thoracic Transplant Registry, on 15,885 adult primary heart transplant recipients with known CMV serologic status between 7/2004 and 6/2014. Read More

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September 2021

Healthcare Resource Utilization After Living Liver Donation: A Retrospective Case-control Study.

Transplantation 2021 Sep 23. Epub 2021 Sep 23.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea. Department of Information Statistics, Andong National University, Andong, South Korea. Department of Statistics, Kyungpook National University, Daegu, South Korea. Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.

Background: Living liver donation is generally considered safe, but donors may experience short or long-term complications. The purpose of this study was to assess healthcare resource utilization after liver donation in living liver donors in comparison to the general population.

Methods: Outpatient or emergency department visits and hospital admissions were compared between living liver donors who underwent hepatic resection for living liver donation between 2004 and 2018 and the matched general population. Read More

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September 2021

Healthcare practitioners' diagnostic and treatment practice patterns of nonalcoholic fatty liver disease in Poland: a cross-sectional survey.

Eur J Gastroenterol Hepatol 2021 Sep 21. Epub 2021 Sep 21.

Department of Gastroenterology and Hepatology, Medical University of Silesia, Katowice Department of Family Medicine, Wrocław Medical University, Wrocław Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gdańsk Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland Consumer Health Care Medical Affairs, Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany PEX PharmaSequence Consumer Health Care Scientific Affairs, Sanofi-Aventis Sp. z o.o, Warsaw, Poland.

Background: Nonalcoholic fatty liver disease (NAFLD) awareness is low. NAFLD diagnosis and management by gastroenterologists (GEs) and general practitioners (GPs) in Poland were evaluated.

Methods: RESTORE was an observational, noninterventional, retrospective cross-sectional survey performed among GEs and GPs with at least 3 years' experience. Read More

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September 2021

Safety and efficacy of sofosbuvir/ledipasvir and sofosbuvir/daclatasvir in the treatment of hepatitis C in patients with decompensated cirrhosis.

Eur J Gastroenterol Hepatol 2021 Sep 21. Epub 2021 Sep 21.

Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo Tropical medicine, Faculty of Medicine, Alexandria University, Alexandria Endemic Medicine and Hepatology Department, Faculty of Medicine, Cairo University Department of Internal Medicine, Al-Azhar University Tropical Medicine Department, Faculty of Medicine, Ain Shams University, Cairo Department of community medicine, Faculty of Medicine, Suez Canal University Hepatogastroenterology Department, National Hepatology & Tropical Medicine Research Institute, Cairo Gastroenterology Department, Damietta Cardiology and Gastroenterology Center, Damietta Hepatology and Gastroenterology Department, AGOZA Police Hospital, Cairo Epidemiology and Preventive Medicine Department, National Liver Institute, Menoufia University, Menoufia, Egypt Hepatology and gastroenterology department, national liver institute.Menoufia University, Egypt.

Background: Hepatitis C virus (HCV)-related decompensated cirrhosis is a severe life-threatening illness. The safety of direct-acting antivirals (DAAs) has opened a gate of hope for that subgroup of patients who were previously contraindicated for interferon therapy.

Objective: We aimed at the investigation of the safety and efficacy of different DAAs regimens in the treatment of HCV-related decompensated cirrhosis patients, to determine sustained virological response (SVR)12 rates and to analyze the factors associated with response. Read More

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September 2021

Electromyographic assessment of condylar screw placement during occipitocervical fusion.

J Neurosurg Spine 2021 Sep 24:1-10. Epub 2021 Sep 24.

1Neurological Surgery Professional Corporation, Rockville Centre; and.

Objective: This is a retrospective study of a series of occipitocervical fusion procedures with condylar screw fixation in which the authors investigated the utility of electromyography (EMG, free-running and triggered) as a reliable tool in assessing the positioning of condylar screws. This series consisted of 197 patients between 15 and 60 years of age who presented with craniocervical instability, and who were treated between October 2014 and December 2017.

Methods: Intraoperative free-running EMG was observed at the placement of condylar screws, as well as at realigning of the spine. Read More

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September 2021

The safety and efficacy of dexamethasone in the perioperative management of glioma patients.

J Neurosurg 2021 Sep 24:1-8. Epub 2021 Sep 24.

1Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Objective: In this single-institution retrospective cohort study, the authors evaluated the effect of dexamethasone on postoperative complications and overall survival in patients with glioma undergoing resection.

Methods: A total of 435 patients who underwent resection of a primary glioma were included in this retrospective cohort study. The inclusion criterion was all patients who underwent resection of a primary glioma at a tertiary medical center between 2014 and 2019. Read More

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September 2021

Clinical and radiologic outcomes after stereotactic radiosurgery for meningiomas in direct contact with the optic apparatus: an international multicenter study.

J Neurosurg 2021 Sep 24:1-7. Epub 2021 Sep 24.

17Department of Radiation Oncology, University of Southern California, Los Angeles, California.

Objective: Resection of meningiomas in direct contact with the anterior optic apparatus carries risk of injury to the visual pathway. Stereotactic radiosurgery (SRS) offers a minimally invasive alternative. However, its use is limited owing to the risk of radiation-induced optic neuropathy. Read More

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September 2021

Symptom and clinical recovery outcomes for pediatric concussion following early physical activity.

J Neurosurg Pediatr 2021 Sep 24:1-8. Epub 2021 Sep 24.

3Sports Medicine Center, Children's Hospital Colorado, Aurora.

Objective: Recent research supports initiating physical activity as soon as 24 to 48 hours after concussion to reduce persistent postconcussive symptoms. However, this practice has not been widely adopted. The objective of this study was to evaluate the association of early physical activity with patient-reported and functional outcomes for pediatric patients following a concussion. Read More

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September 2021

Time to return to work after elective lumbar spine surgery.

J Neurosurg Spine 2021 Sep 24:1-9. Epub 2021 Sep 24.

1Combined Neurosurgical and Orthopedic Spine Service, Department of Orthopedic Surgery, University of British Columbia, Vancouver, British Columbia.

Objective: Time to return to work (RTW) after elective lumbar spine surgery is variable and dependent on many factors including patient, work-related, and surgical factors. The primary objective of this study was to describe the time and rate of RTW after elective lumbar spine surgery. Secondary objectives were to determine predictors of early RTW (< 90 days) and no RTW in this population. Read More

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September 2021

Patient outcomes after circumferential minimally invasive surgery compared with those of open correction for adult spinal deformity: initial analysis of prospectively collected data.

J Neurosurg Spine 2021 Sep 24:1-12. Epub 2021 Sep 24.

1Department of Neurosurgery, University of California, San Francisco, San Francisco, California.

Objective: Circumferential minimally invasive spine surgery (cMIS) for adult scoliosis has become more advanced and powerful, but direct comparison with traditional open correction using prospectively collected data is limited. The authors performed a retrospective review of prospectively collected, multicenter adult spinal deformity data. The authors directly compared cMIS for adult scoliosis with open correction in propensity-matched cohorts using health-related quality-of-life (HRQOL) measures and surgical parameters. Read More

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September 2021

Multiple-rod constructs and use of bone morphogenetic protein-2 in relation to lower rod fracture rates in 141 patients with adult spinal deformity who underwent lumbar pedicle subtraction osteotomy.

J Neurosurg Spine 2021 Sep 24:1-11. Epub 2021 Sep 24.

2Department of Neurological Surgery, University of California, San Francisco; and.

Objective: The purpose of this study was to compare rod fracture (RF) rates among three types of rod constructs (RCs) following lumbar pedicle subtraction osteotomy (PSO) for adult spinal deformity (ASD).

Methods: A retrospective review of consecutive patients with adult spinal deformity who were treated with lumbar PSO between 2007 and 2017 was performed. The minimum follow-up was 2 years. Read More

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September 2021

Dose to neuroanatomical structures surrounding pituitary adenomas and the effect of stereotactic radiosurgery on neuroendocrine function: an international multicenter study.

J Neurosurg 2021 Sep 24:1-9. Epub 2021 Sep 24.

20Centro Gamma Knife Dominicano and Radiology Department, CEDIMAT, Santo Domingo, Dominican Republic.

Objective: Stereotactic radiosurgery (SRS) provides a safe and effective therapeutic modality for patients with pituitary adenomas. The mechanism of delayed endocrine deficits based on targeted radiation to the hypothalamic-pituitary axis remains unclear. Radiation to normal neuroendocrine structures likely plays a role in delayed hypopituitarism after SRS. Read More

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September 2021

Risk factors for unchanged ventricles during pediatric shunt malfunction.

J Neurosurg Pediatr 2021 Sep 24:1-7. Epub 2021 Sep 24.

1Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville.

Objective: Children whose ventricles do not change during shunt malfunction present a diagnostic dilemma. This study was performed to identify risk factors for unchanged ventricular size at shunt malfunction.

Methods: This retrospective 1:1 age-matched case-control study identified children with shunted hydrocephalus who underwent shunt revision with intraoperative evidence of malfunction at one of the three participating institutions from 1997 to 2019. Read More

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September 2021

Comparison of lateral neck X-ray to neck CT in patients with suspicious bone impaction: "Old habits die hard".

Am J Otolaryngol 2021 Sep 16;43(1):103237. Epub 2021 Sep 16.

Department of Otolaryngology and Head and Neck Surgery, Sheba Medical Center, Tel Hashomer 526200, Israel; Sackler Faculty of Medicine, Tel Aviv University, 6997802, Israel. Electronic address:

Objective: Bone impaction (BI) is a common cause for emergency room visits. Among foreign bodies, fish bone is considered the most common. The sensitivity of symptoms in predicting BI is relatively low, making imaging a central tool to aid diagnosis. Read More

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September 2021

Laryngeal disorders in people living with HIV.

Am J Otolaryngol 2021 Sep 20;43(1):103234. Epub 2021 Sep 20.

Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States of America.

Objectives: Several studies have shown that HIV infected individuals are at higher risk compared to the general population of developing non-AIDS defining conditions such as some types of cancer, kidney disease, liver disease and others. In this case-control study, we compared the incidence of laryngeal disorders between a treatment-seeking HIV-positive population and uninfected controls. We aimed to investigate whether there are any laryngeal disorders that are overrepresented in HIV-positive individuals. Read More

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September 2021

Lessons learned from safe tracheostomy aftercare taskforce implemented during COVID-19 pandemic.

Am J Otolaryngol 2021 Sep 16;43(1):103240. Epub 2021 Sep 16.

Department of Otolaryngology-Head and Neck Surgery, Columbia University Irving Medical center, New York, NY 10032, USA. Electronic address:

Purpose: At the height of the COVID-19 pandemic, our institution instituted a Safe Tracheostomy Aftercare Taskforce (STAT) team to care for the influx of patients undergoing tracheostomies. This review was undertaken to understand this team's impact on outcomes of tracheostomy care.

Methods: We compared retrospective data collected from patients undergoing tracheostomies at our institution from February to June 2019, prior to creation of the STAT team, to prospectively collected data from tracheostomies performed from February to June 2020, while the STAT team was in place and performed statistical analysis on outcomes of care such as decannulation prior to discharge, timely tube change, and post-discharge follow-up. Read More

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September 2021

Evaluation of per- and poly-fluorinated alkyl substances (PFAS) in livers of bottlenose dolphins (Tursiops truncatus) found stranded along the northern Adriatic Sea.

Environ Pollut 2021 Sep 18;291:118186. Epub 2021 Sep 18.

Department of Comparative Biomedicine and Food Science BCA, University of Padova, Agripolis, Viale Dell'Università, 16, 35020, Legnaro, PD, Italy.

Per-and poly-fluorinated alkyl substances (PFAS) are a group of chemicals used in a wide variety of commercial products and industrial applications. These chemicals are persistent, can accumulate in humans' and animals' tissues and in the environment, representing an increasing concern due to their moderate to highly toxicity. Their global distribution, persistence and toxicity led to an urgent need to investigate bioaccumulation also in marine species. Read More

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September 2021