2,689,788 results match your criteria incidence prevalence


Surveillance imaging during first remission in follicular lymphoma does not impact overall survival.

Cancer 2021 Jun 22. Epub 2021 Jun 22.

Department of Hematology and Medical Oncology, Emory University-Winship Cancer Institute, Atlanta, Georgia.

Background: Although many patients with follicular lymphoma (FL) undergo routine radiographic surveillance during their first remission, no consensus exists on the modality, duration, frequency, or need for routine imaging studies. The authors retrospectively examined the effect of surveillance imaging on relapse detection and overall survival (OS) in patients with FL.

Methods: Patients with newly diagnosed FL who had a response to induction therapy were identified from the Lymphoid Malignancies Enterprise Architecture Database (LEAD) at Emory University and from the Molecular Epidemiology Resource (MER) of the University of Iowa/Mayo Clinic. Read More

View Article and Full-Text PDF

Prevalence and risk factors of undiagnosed diabetes mellitus among gastroenterological patients: a HbA1c-based single center experience.

Z Gastroenterol 2021 Jun 22. Epub 2021 Jun 22.

I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: Diabetes mellitus is a major risk factor for microvascular disease, leading to chronic kidney injury or cardiovascular disease, but there is a tremendous proportion of patients worldwide who suffer from undiagnosed diabetes. Until now, little is known about the prevalence of undiagnosed diabetes in gastroenterology inpatients.

Objective: To improve detection of undiagnosed diabetes, a routine screening procedure for gastroenterology inpatients, based on hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) measurement, was established. Read More

View Article and Full-Text PDF

Incidence of cardiac arrhythmias and left ventricular hypertrophy in recreational scuba divers.

Diving Hyperb Med 2021 Jun;51(2):190-198

Divers Alert Network, Durham, North Carolina, USA.

Introduction: The aims of this study were to investigate the potential impact of age, sex and body mass index (BMI) upon the incidence of arrhythmias pre- and post- diving, and to identify the prevalence of left ventricular hypertrophy (LVH) in older recreational divers.

Methods: Divers aged ≥ 40 years participating in group dive trips had ECG rhythm and echocardiograph recordings before and after diving. Arrhythmias were confirmed by an experienced human reader. Read More

View Article and Full-Text PDF

Sinus barotrauma in diving.

Diving Hyperb Med 2021 Jun;51(2):182-189

Department of Otorhinolaryngology - Head and Neck Surgery, Head and Neck Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Introduction: Sinus barotrauma is a common occurrence in diving and subaquatic medicine, potentially compromising dive safety. To gain a more thorough understanding of the condition, an in-depth investigation is justified.

Methods: This was a survey study. Read More

View Article and Full-Text PDF

Retrospective review of enquiries to the Québec diving medicine call centre: 2004 through 2018.

Diving Hyperb Med 2021 Jun;51(2):152-160

Department of Kinesiology, Université Laval, Québec, QC, Canada.

Introduction: The Centre de Médecine de Plongée du Québec (CMPQ) established a bilingual 24-hour dive emergency call line and diving medicine information service in 2004. The toll-free number (888-835-7121) works throughout Canada. Calls and emails (cmpq. Read More

View Article and Full-Text PDF

Mortality rate during professionally guided scuba diving experiences for uncertified divers, 1992-2019.

Diving Hyperb Med 2021 Jun;51(2):147-151

Professional Association of Diving Instructors (PADI Worldwide Corp), Rancho Santa Margarita, CA, USA.

Introduction: The aim of this study was to re-examine the mortality rate among participants in the Professional Association of Diving Instructors' (PADI)'s Discover Scuba Diving (DSD) programme.

Methods: Fatalities reported to PADI as having occurred during DSD scuba dives were counted for each year between 1992 and 2019. DSD participant registrations were also counted for each year. Read More

View Article and Full-Text PDF

[Health consequences (mortality and institutionalization) of hip fracture among the elderly people: Population cohort study in Segovia].

Aten Primaria 2021 Jun 19;53(9):102129. Epub 2021 Jun 19.

Medicina de Familia y Comunitaria, Centro de Salud Segovia 1 y Unidad Docente Multiprofesional de Atención Familiar y Comunitaria de Segovia, Segovia, España.

Objective: In order to know the social and health consequences of hip fractures (HF).

Design: A retrospective cohort study of an entire health area was carried out in patients aged 75 or more, over a period of 5 years. SITE: Segovia Health Area. Read More

View Article and Full-Text PDF

Intra-scanner repeatability of quantitative imaging features in a 3D printed semi-anthropomorphic CT phantom.

Eur J Radiol 2021 Jun 9;141:109818. Epub 2021 Jun 9.

Department of Radiology, Charité - Universitätsmedizin Berlin, Germany; Berlin Institute of Health, Berlin, Germany.

Objectives: Radiomics has shown to provide novel diagnostic and predictive disease information based on quantitative image features in study settings. However, limited data yielded contradictory results and important questions regarding the validity of the methods remain to be answered. The purpose of this study was to evaluate how clinical imaging techniques affect the stability of radiomics features by using 3D printed anthropomorphic CT phantom to test for repeatability and reproducibility of quantitative parameters. Read More

View Article and Full-Text PDF

The association of phasic irritability (aggressive outbursts) and tonic irritability (irritable mood) to depression occurrences, symptoms, and subtypes.

J Affect Disord 2021 Jun 11;293:9-18. Epub 2021 Jun 11.

Vanderbilt University, Nashville, Tennessee.

Background: Research among adults has rarely differentiated between tonic irritability (i.e., irritable mood) and phasic irritability (i. Read More

View Article and Full-Text PDF

IL-38 as an early predictor of the ischemic stroke prognosis.

Cytokine 2021 Jun 19;146:155626. Epub 2021 Jun 19.

School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Background: Ischemic stroke is caused by a sudden neurological defect following a vascular occlusion and elicits a local and systemic inflammation in brain tissue. Interleukin-38 is an anti-inflammatory cytokine associated with ischemic and inflammatory diseases. This study was designed to analyze the effect of tPA therapy on interleukin-38 serum level changes and the serum level of IL-38 in the prognosis of ischemic stroke patients in the next three months. Read More

View Article and Full-Text PDF

Is IV contrast necessary for MRI follow-up in children with abdominal neuroblastoma?

Clin Imaging 2021 Jun 18;79:259-264. Epub 2021 Jun 18.

Dept. Radiology, Memorial Sloan Kettering Cancer Center, United States of America.

Purpose: The safety of multiple doses of gadolinium-based MRI IV contrast has recently been called in to question. While the long-term safety is being investigated, here, we seek to determine if there is added value to the use of IV contrast for improving detection of tumoral recurrences in children with a history of abdominal neuroblastoma.

Methods: This is a retrospective review of children who underwent abdominal MRI with gadolinium contrast. Read More

View Article and Full-Text PDF

50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study.

EBioMedicine 2021 Jun 19;69:103439. Epub 2021 Jun 19.

Divison of Pulmonary, Critical Care & Sleep Medicine. University of South Florida, Morsani College of Medicine, Tampa, FL 33602, USA. Electronic address:

Background: COVID-19 has been associated with Interstitial Lung Disease features. The immune transcriptomic overlap between Idiopathic Pulmonary Fibrosis (IPF) and COVID-19 has not been investigated.

Methods: we analyzed blood transcript levels of 50 genes known to predict IPF mortality in three COVID-19 and two IPF cohorts. Read More

View Article and Full-Text PDF

Severe Maternal Morbidity and Mortality During Delivery Hospitalization of Class I, II, III, and Super Obese Women.

Am J Obstet Gynecol MFM 2021 Jun 19:100420. Epub 2021 Jun 19.

Yale School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, New Haven, Connecticut.

Background: Previous studies show that obesity predisposes patients to higher risks of adverse pregnancy outcomes. Data on the relationship between increasing degrees of obesity and risks of severe maternal morbidity (SMM), including mortality, are limited.

Objective: We examined the association of increasing classes of obesity, especially super obesity, with the risk of SMM and mortality at the time of delivery hospitalization. Read More

View Article and Full-Text PDF

Estimating heterogeneous survival treatment effects of lung cancer screening approaches: A causal machine learning analysis.

Ann Epidemiol 2021 Jun 19. Epub 2021 Jun 19.

Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

The National Lung Screening Trial (NLST) found that low-dose computed tomography (LDCT) screening provided lung cancer (LC) mortality benefit compared to chest radiography (CXR). Considerable research concerns identifying the differential treatment effects that may exist in certain subpopulations. We shed light on several important issues in existing research and highlight the need for further investigation of the heterogeneous comparative effect of LDCT versus CXR, using more flexible and rigorous statistical approaches. Read More

View Article and Full-Text PDF

Subpatent Plasmodium with mutant pfmdr1, pfcrt and pvmdr1 alleles from endemic provinces in Mindanao, The Philippines: implications for local malaria elimination.

Int J Infect Dis 2021 Jun 19. Epub 2021 Jun 19.

Dept of Infection Biology, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; PHE Malaria Reference Laboratory, London School of Hygiene & Tropical Medicine, London, UK. Electronic address:

Objectives: This study identifies and characterises circulating Plasmodium species in three provinces of Mindanao approaching malaria elimination.

Methods: RDT, microscopic examination and PCR were used to detect malaria parasites. PCR-positive isolates were genotyped for polymorphisms in loci of interest. Read More

View Article and Full-Text PDF

Is convalescent plasma futile in COVID-19? A Bayesian re-analysis of the RECOVERY randomised controlled trial.

Int J Infect Dis 2021 Jun 19. Epub 2021 Jun 19.

Institute of Applied Health Research, University of Birmingham, UK.

View Article and Full-Text PDF

Using a stepwise approach to simultaneously develop and validate Machine Learning based prediction models: Stepwise model development and validation.

J Clin Epidemiol 2021 Jun 19. Epub 2021 Jun 19.

Department of Epidemiology, Medisch Spectrum Twente, Enschede, the Netherlands.

Accurate diagnosis of a disease is essential in healthcare. Prediction models, based on classical regression techniques, are widely used in clinical practice. Machine Learning (ML) techniques might be preferred in case of a large amount of data per patient and relatively limited numbers of subjects. Read More

View Article and Full-Text PDF

Growth Rates of Infants Randomized to CPAP or Intubation After Extremely Preterm Birth.

J Pediatr 2021 Jun 19. Epub 2021 Jun 19.

National Institute of Child Health and Human Development, Bethesda, MD and Department of Global and Community Health, George Mason University, Fairfax, VA.

Objective: To evaluate the effects of early treatment with CPAP on nutritional intake and in-hospital growth rates of extremely preterm (EPT) infants.

Study Design: EPT infants (24-0/7 to 27-6/7 weeks of gestation) enrolled in the Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT) were included. EPT infants who died before 36 weeks' postmenstrual age (PMA) were excluded. Read More

View Article and Full-Text PDF

Infective Endocarditis and Solid Organ Transplantation: Only worse outcomes during initial transplantation hospitalization.

Am Heart J 2021 Jun 19. Epub 2021 Jun 19.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA; Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Introduction: The epidemiology, and outcome of infective endocarditis (IE) among solid organ transplant (SOT) recipients is unknown.

Methods: We used data from the 2013-2018 Nationwide Readmissions Database (NRD). IE- and SOT-associated hospitalizations were identified using diagnosis and procedure codes. Read More

View Article and Full-Text PDF

Poor Odor Identification Predicts Mortality Risk in Older Adults Without Neurodegenerative Diseases: The Shanghai Aging Study.

J Am Med Dir Assoc 2021 Jun 19. Epub 2021 Jun 19.

Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

View Article and Full-Text PDF

Subgroups of failure after surgery for pelvic organ prolapse and associations with quality of life outcomes: a longitudinal cluster analysis.

Am J Obstet Gynecol 2021 Jun 19. Epub 2021 Jun 19.

NICHD.

Background: Treatment outcomes after pelvic organ prolapse (POP) surgery are often presented as dichotomous 'success or failure' based upon anatomic and symptom criteria. However, clinical experience suggests some women with outcome 'failures' are asymptomatic and perceive their surgery to be successful, while others have anatomic resolution, but continue to report symptoms. Characterizing failure types could be a useful step to refine definitions of success, understand mechanisms of failure, and identify individuals who may benefit from specific therapies. Read More

View Article and Full-Text PDF

Vision, Eye Disease, and the Onset of Balance Problems: The Canadian Longitudinal Study on Aging: Vision and Balance Problems.

Am J Ophthalmol 2021 Jun 19. Epub 2021 Jun 19.

School of Epidemiology and Public Health, University of Ottawa, Ottawa; University of Ottawa Eye Institute, Ottawa; Ottawa Hospital Research Institute, Ottawa; Canada. Electronic address:

Purpose: To understand the relationship between visual impairment, self-reported eye disease, and the onset of balance problems.

Design: Population-based prospective cohort study METHODS: : Baseline and 3-year follow-up data were used from the Canadian Longitudinal Study on Aging. The Comprehensive Cohort included 30,097 adults ages 45-85 years old recruited from 11 sites across 7 provinces. Read More

View Article and Full-Text PDF

Residential green space can shape the indoor microbial environment.

Environ Res 2021 Jun 19:111543. Epub 2021 Jun 19.

Center for Environment and Health, Department of Public Health, Leuven University (KU Leuven) , Belgium; Social Epidemiology and Health Policy, Department of Family Medicine and Population Health, University of Antwerp; Belgium.

Background: The influence of outdoor green space on microbial communities indoors has scarcely been investigated. Here, we study the associations between nearby residential green space and residential indoor microbiota.

Methods: We collected settled dust from 176 living rooms of participants of the ENVIRONAGE birth cohort. Read More

View Article and Full-Text PDF

Effects of high-frequency temperature variabilities on the morbidity of chronic obstructive pulmonary disease: Evidence in 21 cities of Guangdong, South China.

Environ Res 2021 Jun 19:111544. Epub 2021 Jun 19.

School of Geography and Planning, Sun Yat-sen University, Guangzhou, China. Electronic address:

Background: While temperature changes have been confirmed as one of the contributory factors affecting human health, the association between high-frequency temperature variability (HFTV, i.e., temperature variation at short time scales such as 1, 2, and 5 days) and the hospitalization of chronic obstructive pulmonary disease (COPD) was rarely reported. Read More

View Article and Full-Text PDF

Prevalence of metabolic syndrome and its correlation with sexual dysfunction in adult psychiatric patients treated with psychotropics in a tertiary care hospital.

Int J Clin Pract 2021 Jun 22:e14559. Epub 2021 Jun 22.

Department of Pharmacy Practice, Vinayaka Mission's College of Pharmacy, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, 636008, Tamil Nadu, India.

Background: In the past two decades, there has been a profound increase in the incidence of metabolic disorders among the general population, and psychotropics are also said to play a major role in the development of metabolic syndrome.

Aim: Determining the prevalence of Metabolic Syndrome (MetS) and sexual dysfunction (SD) and their correlation in psychiatric patients treated with psychotropics in a tertiary care hospital in Salem region, Tamilnadu, India.

Materials And Methods: A cross-sectional study was conducted in the psychiatric department of Vinayaka Mission's Medical College and Hospitals, Salem on patients (n=108) treated with psychotropics. Read More

View Article and Full-Text PDF

Parasitism and host dispersal plasticity in an aquatic model system.

J Evol Biol 2021 Jun 22. Epub 2021 Jun 22.

ISEM, University of Montpellier, CNRS, EPHE, IRD, Montpellier, France.

Dispersal is a central determinant of spatial dynamics in communities and ecosystems, and various ecological factors can shape the evolution of constitutive and plastic dispersal behaviours. One important driver of dispersal plasticity is the biotic environment. Parasites, for example, influence the internal condition of infected hosts and define external patch quality. Read More

View Article and Full-Text PDF

Persistent symptoms in Swedish children after hospitalisation due to COVID-19.

Acta Paediatr 2021 Jun 22. Epub 2021 Jun 22.

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.

COVID-19 is generally mild in children and post-acute inflammatory conditions that are temporally associated with the virus are rare, but potentially severe. However, some children and adults experience persistent symptoms after COVID-19. Long COVID has not been precisely defined, but one study reported symptoms approximately 60 days after the primary diagnosis. Read More

View Article and Full-Text PDF

Proven COVID-19-associated pulmonary aspergillosis in patients with severe respiratory failure.

Mycoses 2021 Jun 22. Epub 2021 Jun 22.

Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Pathology Unit, University of Padova, Medical School, Padova, Italy.

Background: An increasing number of reports have described the COVID-19 associated pulmonary aspergillosis (CAPA) as being a further contributing factor to mortality. Based on a recent consensus statement supported by international medical mycology societies, it has been proposed to define CAPA as possible, probable, or proven on the basis of sample validity and thus diagnostic certainty. Considering current challenges associated with proven diagnoses there is pressing need to study the epidemiology of proven CAPA. Read More

View Article and Full-Text PDF

Comment on the paper: Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines.

Eur J Pain 2021 Jun 22. Epub 2021 Jun 22.

Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.

Corp et al. conducted an important study to synthesize the evidence from European guidelines on neck and lower back pain to identify appropriate recommendations (Corp et al., 2021). Read More

View Article and Full-Text PDF

Post-9/11 excess risk of thyroid cancer: Surveillance or exposure?

Am J Ind Med 2021 Jun 22. Epub 2021 Jun 22.

Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

An excess risk of thyroid cancer has been reported in different World Trade Center (WTC)-dust exposed cohorts. Increased surveillance of these cohorts has been suggested as a potential explanation of this reported excess thyroid cancer risk leading to an increased diagnosis of earlier-stage thyroid cancers. However, the uncertainty to what extent surveillance or physician bias may be contributing to the reported incidence of thyroid cancer in WTC-dust exposed populations remains, highlighting the need to investigate a potential causal link between WTC dust exposure and thyroid cancer. Read More

View Article and Full-Text PDF