39,329 results match your criteria improved stability

Developing a simple box-behnken experimental design on the removal of doxorubicin anticancer drug using FeO/graphene nanoribbons adsorbent.

Environ Res 2021 Jun 12;200:111522. Epub 2021 Jun 12.

Department of Chemical Sciences (formerly Department of Applied Chemistry), University of Johannesburg, P.O. Box 17011, Doornfontein Campus, Johannesburg, 2028, South Africa.

This paper aims to develop a Box-Behnken experimental design system to optimize the removal process of doxorubicin anticancer drugs. For this goal, FeO/graphene nanoribbons was selected as adsorbent and removal of doxorubicin anticancer drug optimized using Box-Behnken experimental design with a selection of four effective factors. A three-level, four-factor Box-Behnken experimental design was used to assess the relationship between removal percentage as a dependent variable with adsorption weight (0. Read More

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Temperature Behavior of SAW Resonators Based on LiNbO3/Quartz and LiTaO3/Quartz Substrates.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 Jun 15;PP. Epub 2021 Jun 15.

LiNbO3 (LN) or LiTaO3 (LT) thin plates bonded to quartz are novel types of layered substrates for temperature-compensated surface acoustic wave (TCSAW) devices. In SAW resonators with Al electrodes arranged on LT/quartz and LN/quartz substrates, improved temperature behavior due to opposite signs of temperature coefficients of frequency (TCF) in quartz substrates and LT or LN plates can be combined with high Q-factors if the quartz orientation is optimized. The quartz orientation areas that enabled high Q-factors were deduced from analyzing the quartz anisotropy and the characteristics of shear horizontally polarized (SH) waves were calculated in the optimal orientations as functions of the quartz cut angle and plate thickness. Read More

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Polymer-Based Honeycomb Films on Bioactive Glass: Toward a Biphasic Material for Bone Tissue Engineering Applications.

ACS Appl Mater Interfaces 2021 Jun 15. Epub 2021 Jun 15.

Laboratory of Biomaterials and Tissue Engineering, Faculty of Medicine and Health Technology, Tampere University, Korkeakoulunkatu 3, 33720 Tampere, Finland.

The development of innovative materials for bone tissue engineering to promote bone regeneration while avoiding fibrous tissue infiltration is of paramount importance. Here, we combined the known osteopromotive properties of bioactive glasses (BaGs) with the biodegradability, biocompatibility, and ease to shape/handle of poly-l--d,l-lactic acid (PLDLA) into a single biphasic material. The aim of this work was to unravel the role of the surface chemistry and topography of BaG surfaces on the stability of a PLDLA honeycomb membrane, in dry and wet conditions. Read More

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Mathematical modeling of COVID-19 in India and its states with optimal control.

Model Earth Syst Environ 2021 Jun 10:1-16. Epub 2021 Jun 10.

Division of Mathematics, School of Advanced Sciences, Vellore Institute of Technology, Chennai, India.

A pandemic is an epidemic spread over a huge geographical area. COVID-19 is such pandemic documented after 1918 flu pandemic. In this work, we frame a mathematical epidemic model taking inspiration from the classic SIR model and develop a compartmental model with ten compartments to study the coronavirus dynamics in India and three of its most affected states, namely, Maharashtra, Karnataka, and Tamil Nadu, with inclusion of factors related to face mask efficacy, contact tracing, and testing along with quarantine and isolation. Read More

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Overexpression and characterization of a novel GH4 galactosidase with β-galactosidase activity from Bacillus velezensis SW5.

J Dairy Sci 2021 Jun 11. Epub 2021 Jun 11.

Zhejiang International Maritime College, Zhoushan 316021, People's Republic of China.

A novel galactosidase gene (gal3149) was identified from Bacillus velezensis SW5 and heterologously expressed in Escherichia coli BL21 (DE3). The novel galactosidase, Gal3149, encoded by gal3149 in an open reading frame of 1,299 bp, was 433 amino acids in length. Protein sequence analysis showed that Gal3149 belonged to family 4 of glycoside hydrolases (GH4). Read More

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An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability.

Chem Sci 2019 Dec 18;11(7):1985-1990. Epub 2019 Dec 18.

Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation, Hunan Provincial Engineering Research Center for Food Processing of Aquatic Biotic Resources, School of Chemistry and Food Engineering, Changsha University of Science and Technology Changsha 410114 P. R. China

Enzyme-free amplification techniques based on dynamic DNA self-assembly (DDSA) have recently been developed for the detection of mRNA in living cells. However, signal generation in traditional DDSA amplifiers is mainly dependent on the random diffusion of dissociative probes in a bulk solution, which is generally accompanied by poor kinetics and interference from complex biological systems. In this work, a new amplifier based on the design of an intramolecular catalytic hairpin assembly (intra-CHA) is proposed for the FRET imaging of mRNA in living cells. Read More

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December 2019

An ornithine-rich dodecapeptide with improved proteolytic stability selectively kills gram-negative food-borne pathogens and its action mode on Escherichia coli O157:H7.

Int J Food Microbiol 2021 Jun 8;352:109281. Epub 2021 Jun 8.

State Key Laboratory of Chemical Biology and Drug Discovery and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

Food-borne pathogenic bacteria are dispersed throughout the entire chain of the food industry. However, many food preservatives are limited by poor biocompatibility such as cumulative poisoning. The antimicrobial peptide is increasingly regarded as a promising preservative in food research due to its high bioactivity and low cytotoxicity. Read More

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The implementation of graphene-based aerogel in the field of supercapacitor.

Nanotechnology 2021 Jun 14;32(36). Epub 2021 Jun 14.

Centre of Interdisciplinary Research, D. Y. Patil University, Kolhapur, 416006, Maharashtra, India.

Graphene and graphene-based hybrid materials have emerged as an outstanding supercapacitor electrode material primarily because of their excellent surface area, high electrical conductivity, and improved thermal, mechanical, electrochemical cycling stabilities. Graphene alone exhibits electric double layer capacitance (EDLC) with low energy density and high power density. The use of aerogels in a supercapacitor is a pragmatic approach due to its extraordinary properties like ultra-lightweight, high porosity and specific surface area. Read More

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Nafion-Based Proton-Exchange Membranes Built on Cross-Linked Semi-Interpenetrating Polymer Networks between Poly(acrylic acid) and Poly(vinyl alcohol).

ACS Appl Mater Interfaces 2021 Jun 14. Epub 2021 Jun 14.

Organic Material Synthesis Laboratory, Department of Chemistry, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea.

We report semi-interpenetrating polymer network (semi-IPN) membranes prepared easily from a cross-linked network using poly(acrylic acid) (PAA) and poly(vinyl alcohol) (PVA) with interpenetrated Nafion for both proton-exchange membrane fuel cell (PEMFC) and proton-exchange membrane water electrolyzer (PEMWE) applications. Thermal esterification between PAA and PVA induced three-dimensional cross-linking to improve mechanical toughness and reduce hydrogen crossover, while the hydrophilic nature of the PAA-PVA-based cross-linked matrix still enhanced the water uptake (WU) and hence conductivity of the Nafion penetrant. The semi-IPN membrane (NPP-95) composed of Nafion, PAA, and PVA with a ratio of 95:2. Read More

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Albumin-Templated BiSe-MnO Nanocomposites with Promoted Catalase-Like Activity for Enhanced Radiotherapy of Cancer.

ACS Appl Mater Interfaces 2021 Jun 14. Epub 2021 Jun 14.

National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.

Novel and effective radiosensitizers that can enhance radiosensitivity of tumor tissues and increase the local radiation dose are highly desirable. In this work, templated by bovine serum albumin (BSA), BiSe-MnO nanocomposites ([email protected]) were fabricated via biomineralization, while BiSe nanodots act as radiosensitizers to increase the local radiation dosage because of their strong X-ray attenuation ability, and MnO with catalase-like activity can increase the oxygen concentration in tumors by triggering the decomposition of tumor endogenous HO so as to improve the hypoxia-associated radioresistance of tumors. Owing to the interaction of the two components in the interface, [email protected] showed promoted catalytic activity compared to [email protected], favoring tumor radiotherapy (RT) sensitization. Read More

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Deep-level transient spectroscopy for effective passivator selection in perovskite solar cells to attain high efficiency over 23.

ChemSusChem 2021 Jun 13. Epub 2021 Jun 13.

Shaanxi Normal University, School of Materials Science and Engineering, No. 620, West Chang'an Avenue, Chang'an District, Xi'an, Shaanxi, 710119, Xi'an, CHINA.

Most studies choose passivators essentially in a trial-and-error fashion in an attempt to attain high efficiency in perovskite solar cells (PSCs). Using deep-level transient spectroscopy (DLTS) measurements, we firstly determined the type of defects in perovskite films to guide the passivator selection for PSCs. There are three kinds of positively charged defects found in our target PSC system. Read More

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Study on the Fluidization Quality Characterization Method and Process Intensification of Fine Coal Separation in a Vibrated Dense Medium Fluidized Bed.

ACS Omega 2021 Jun 25;6(22):14268-14277. Epub 2021 May 25.

School of Chemistry and Environmental Engineering, North China Institute of Science & Technology, Sanhe 065201, China.

Uniform and stable bed density is the basis of efficient coal separation by a gas-solid dense medium fluidized bed. The traditional air dense medium fluidized bed (ADMFB) is a kind of bubbling bed. By introducing vibration energy, a vibrated dense medium fluidized bed (VDMFB) with uniform and stable bed density can be formed, where the bubble merger is suppressed, the gas-solid contact can is strengthened, and the fluidization quality is also improved. Read More

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Investigation of the Turbulent Boundary Layer Structure over a Sparsely Spaced Biomimetic Spine-Covered Protrusion Surface.

ACS Omega 2021 Jun 28;6(22):14220-14229. Epub 2021 May 28.

College of Mechanical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212003, China.

Multiperspective particle image velocimetry was used to investigate the turbulent boundary layer structure over biomimetic spine-covered protrusion (BSCP) samples inspired by dorsal skin of pufferfish. The comparison of BSCP samples of two sparse "-type" arrangements (aligned and staggered) with roughness height = 5-7 (nearly hydraulically smooth) and smooth case were manufactured in bulk Reynolds number = 37,091, 44,510. The negative value of the roughness function Δ shows a downward shift of the mean velocity profile of BSCP samples, which shows a drag reduction effect. Read More

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Investigation on the Distribution of Yimin Lignite Pyrolysis Products and the Stability of its Char.

ACS Omega 2021 Jun 21;6(22):13953-13961. Epub 2021 May 21.

China University of Mining and Technology, Beijing 100083, China.

This paper introduces the utilization of lignite in China and abroad and studies the influence of different process conditions on the pyrolysis products of lignite. The effects of pyrolysis temperature, residence time, and heating rate on the yield and stability of pyrolysis products were studied by standard lattice low-temperature distillation of coal. The results showed that the final pyrolysis temperature of lignite increases gradually, which is a key factor affecting the pyrolysis performance of lignite. Read More

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Impact of Fermented or Enzymatically Fermented Dried Olive Pomace on Growth, Expression of Digestive Enzyme and Glucose Transporter Genes, Oxidative Stability of Frozen Meat, and Economic Efficiency of Broiler Chickens.

Front Vet Sci 2021 28;8:644325. Epub 2021 May 28.

Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

The use of dried olive pomace as complementary energy sources in poultry feed is still limited due to its low protein and high fiber contents. Bioconversion of olive pomace through solid-state fermentation with or without exogenous enzymes is considered as a trial for improving its nutritional value. This study aimed to evaluate the effects of fermented olive pomace with or without enzymatic treatment on the growth, modulations of genes encoding digestive enzymes and glucose transporters, meat oxidative stability, and economic efficiency of broiler chickens. Read More

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Flexible Intramedullary Nailing of Pediatric Femoral Fractures.

JBJS Essent Surg Tech 2021 Jan-Mar;11(1). Epub 2021 Mar 2.

Washington University in St. Louis, St. Louis, Missouri.

Background: Flexible intramedullary nailing is performed for femoral fractures in pediatric patients who may be too large for spica cast immobilization but who have substantial growth remaining and who are not a candidate for rigid intramedullary nailing. Flexible nailing allows the surgeon to obtain correct alignment of the femur fracture so as to allow for healing without a lower extremity deformity.

Description: The patient is positioned on a radiolucent table, flexible nails are chosen according to the diameter of the medullary canal, medial and lateral incisions are made along the distal aspect of the thigh, and access to the canal is obtained with use of a drill-bit of the appropriate size. Read More

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Complex Revision Glenoid Reconstruction with Use of a Distal Tibial Allograft.

JBJS Essent Surg Tech 2021 Jan-Mar;11(1). Epub 2021 Jan 20.

The Steadman Clinic, Vail, Colorado.

Background: Coracoid transfer procedures have been increasingly utilized for anterior shoulder instability with associated glenoid bone loss. Unfortunately, in a young, high-risk patient population, these procedures can fail secondary to traumatic causes but also because of bone graft resorption or malposition or hardware prominence, among other reasons. In active patients, revision glenoid reconstruction may be indicated. Read More

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January 2021

A Targeted Approach to Evaluating the Golfing Athlete with Low Back Pain: A Resident's Case Report.

Luke Deckard

Int J Sports Phys Ther 2021 Jun 1;16(3):636-650. Epub 2021 Jun 1.

ProRehab Physical Therapy.

Background And Purpose: Low back pain is one of the most common conditions occurring in the golfing population. Many approaches have been utilized throughout the years to address this condition including the concept of regional interdependence. The purpose of this case report is to describe the evaluation process and treatment approach of a golfer with low back pain using the principles of regional interdependence. Read More

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The role of sodium in stabilizing tin-lead (Sn-Pb) alloyed perovskite quantum dots.

J Mater Chem A Mater 2021 Mar 19;9(20):12087-12098. Epub 2021 Mar 19.

Materials Simulation and Modelling, Department of Applied Physics, Eindhoven University of Technology 5600 MB Eindhoven The Netherlands

Narrow-bandgap CsSn Pb I perovskite quantum dots (QDs) show great promise for optoelectronic applications owing to their reduced use of toxic Pb, improved phase stability, and tunable band gaps in the visible and near-infrared range. The use of small ions has been proven beneficial in enhancing the stability and photoluminescence quantum yield (PLQY) of perovskite QDs. The introduction of sodium (Na) has succeeded in boosting the PLQY of CsSnPbI QDs. Read More

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Trialkylammonium salt degradation: implications for methylation and cross-coupling.

Chem Sci 2021 Apr 13;12(20):6949-6963. Epub 2021 Apr 13.

WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building 295 Cathedral Street Glasgow UK

Trialkylammonium (most notably ,,-trimethylanilinium) salts are known to display dual reactivity through both the aryl group and the -methyl groups. These salts have thus been widely applied in cross-coupling, aryl etherification, fluorine radiolabelling, phase-transfer catalysis, supramolecular recognition, polymer design, and (more recently) methylation. However, their application as electrophilic methylating reagents remains somewhat underexplored, and an understanding of their arylation methylation reactivities is lacking. Read More

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An interparticle relatively motional DNA walker and its sensing application.

Chem Sci 2020 Jun 30;11(28):7415-7423. Epub 2020 Jun 30.

School of Chemistry and Chemical Engineering, Shandong University 250100 Jinan P. R. China

DNA molecular machines are DNA self-assemblies that perform quasi-mechanical movement at the micro-nano scale, and have attracted increasing attention in the fields of biosensing, drug delivery and biocomputing. Herein, we report the concept and operation of an interparticle relatively motional DNA walker. The walker is composed of walking particles (WPs) and track particles (TPs). Read More

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Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics.

Chem Sci 2020 May 9;11(20):5221-5226. Epub 2020 May 9.

School of Chemistry, University of Bristol Cantock's Close BS8 1TS Bristol UK

With growing understanding of the underlying pathways of polyketide biosynthesis, along with the continual expansion of the synthetic biology toolkit, it is becoming possible to rationally engineer and fine-tune the polyketide biosynthetic machinery for production of new compounds with improved properties such as stability and/or bioactivity. However, engineering the pathway to the thiomarinol antibiotics has proved challenging. Here we report that genes from a marine sp. Read More

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Combined Effects of Strengthening and Proprioceptive Training on Stability, Balance, and Proprioception Among Subjects with Chronic Ankle Instability in Different Age Groups: Evaluation of Clinical Outcome Measures.

Indian J Orthop 2021 May 15;55(Suppl 1):199-208. Epub 2020 Jul 15.

C/3/139, Department of Medical Rehabilitation (Physical Therapy), College of Applied Medical Sciences, King Khalid University, Guraiger Campus, Abha, Kingdom of Saudi Arabia.

Background: Lateral ankle sprains are among the common injuries in the physically active population in different age groups and progress to chronic ankle instability (CAI). Accordingly, the current study assesses the effectiveness of strengthening and proprioceptive training programs on proprioception and balance in those suffering from CAI.

Design: Quasi-experimental design. Read More

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Targeting the TLR2 Receptor With a Novel Thymopentin-Derived Peptide Modulates Immune Responses.

Front Immunol 2021 27;12:620494. Epub 2021 May 27.

Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.

The innate and adaptive immune systems act in concert to protect us from infectious agents and other harmful substances. As a state of temporary or permanent immune dysfunction, immunosuppression can make an organism more susceptible to infection, organ injury, and cancer due to damage to the immune system. It takes a long time to develop new immunomodulatory agents to prevent and treat immunosuppressive diseases, with slow progress. Read More

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Most frequently asked questions about the coercivity of Nd-Fe-B permanent magnets.

Sci Technol Adv Mater 2021 Jun 4;22(1):386-403. Epub 2021 Jun 4.

Elements Strategy Initiative Center for Magnetic Materials (ESICMM), National Institute for Materials Science, Tsukuba, Japan.

Physically, the coercivity of permanent magnets should scale with the anisotropy field of ferromagnetic compounds, ; however, the typical coercivity values of commercial polycrystalline sintered magnets are only ~0.2 , which is known as Brown's paradox. Recent advances in multi-scale microstructure characterizations using focused ion beam scanning electron microscope (FIB/SEM), aberration corrected scanning transmission electron microscopy (C-corrected STEM), and atom probe tomography (APT) revealed detailed microstructural features of commercial and experimental Nd-Fe-B magnets. Read More

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Application of bioinformatics and molecular dynamics simulation approaches for identification of fibroblast growth factor 10 analogues with potentially improved thermostability.

Growth Factors 2020 Jun-Jul;38(3-4):197-209

Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Fibroblast growth factor 10 functions as a paracrine mesenchymal molecule to initiate signalling pathways regarding to cellular development and health. However, the low thermal stability restricts it's functionality in the human body and the shelf-life of FGF10-based formulations. The current study aimed to employ rational design and bioinformatics approaches to identify some point mutations which may improve the thermal stability of FGF10. Read More

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A new approach on synergistic effect and chemical stability of graphene oxide-magnetic nanocomposite in the heterogeneous Fenton degradation of caffeine.

Environ Sci Pollut Res Int 2021 Jun 14. Epub 2021 Jun 14.

Institute of Chemistry, São Paulo State University (UNESP), Araraquara, SP, 14800-900, Brazil.

Two compositions of graphene oxide-magnetite nanocomposites were studied as catalysts in the heterogeneous Fenton process. Transmission electron microscopy and X-ray diffraction revealed that the graphene oxide sheets were covered with nanoparticles of magnetite, with an average crystallite size of 7 nm. Infrared spectroscopy analysis indicated that the phases interacted through covalent Fe-O-C bonds. Read More

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Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: A case report.

J Orthop Sci 2021 Jun 10. Epub 2021 Jun 10.

Center for Stem Cells and Regenerative Medicine, Tokyo Medical and Dental University, Japan.

Background: The purpose of this study was to compare arthroscopic findings of a degenerative flap and radial tear of the medial meniscus (MM) before and one year after treatment by meniscus repair and synovial mesenchymal stem cell (MSC) transplantation.

Methods: Patients with a degenerative flap and radial MM tear that would generally be treated by meniscectomy were included. The patients ranged in age from 45 to 62 years and all underwent meniscus repair and synovium harvest at time 0. Read More

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Physicochemical properties and oxidative stability of duck fat-added margarine for reducing the use of fully hydrogenated soybean oil.

Food Chem 2021 Jun 1;363:130260. Epub 2021 Jun 1.

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

Soybean oil (SBO) and fully hydrogenated soybean oil (FHSBO) have been used for margarine production. However, SBO-based margarine requires a considerable amount of trans fatty acid-containing FHSBO due to its low melting point. We aimed to reduce the FHSBO content in margarine by employing duck fat, which has a higher melting point than SBO. Read More

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Therapeutic oxygen delivery by perfluorocarbon-based colloids.

Adv Colloid Interface Sci 2021 May 1;294:102407. Epub 2021 May 1.

Harangoutte Institute, 68160 Ste Croix-aux-Mines, France.

After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed untoward effects to the product, the development of perfluorocarbon (PFC)-based O nanoemulsions ("blood substitutes") has come to a low. Yet, significant further demonstrations of PFC O-delivery efficacy have continuously been reported, such as relief of hypoxia after myocardial infarction or stroke; protection of vital organs during surgery; potentiation of O-dependent cancer therapies, including radio-, photodynamic-, chemo- and immunotherapies; regeneration of damaged nerve, bone or cartilage; preservation of organ grafts destined for transplantation; and control of gas supply in tissue engineering and biotechnological productions. PFC colloids capable of augmenting O delivery include primarily injectable PFC nanoemulsions, microbubbles and phase-shift nanoemulsions. Read More

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