Pulm Pharmacol Ther 2021 Apr 12;67:102003. Epub 2021 Feb 12.
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:
Background: Obesity is a correctable factor for uncontrolled bronchial asthma. However, the effects of glucagon-like peptide-1 receptor (GLP-1R) agonist, a recently approved antiobestic drug, on airway hyperresponsiveness (AHR) and immune responses are not known.
Methods: Mice were fed with high-fat diet (HFD, 60% fat) for 8 weeks to induce obesity. Read More