1,022 results match your criteria idiopathic epiretinal

Macular holes following vitrectomy for rhegmatogenous retinal detachment: epiretinal proliferation and spontaneous closure of macular holes.

Graefes Arch Clin Exp Ophthalmol 2021 Apr 20. Epub 2021 Apr 20.

Department of Ophthalmology, Kagoshima University Graduate School of Medicine and Dental Sciences, Kagoshima, Japan.

Purpose: To describe the characteristics and management of full-thickness macular holes (MHs) that develop after pars plana vitrectomy for rhegmatogenous retinal detachment (RD).

Methods: Retrospective, interventional, consecutive case series. Patients who developed secondary full-thickness MHs after prior pars plana vitrectomy for RD over a 6-year period were included. Read More

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A prospective randomized clinical trial comparing nepafenac, intravitreal triamcinolone and no adjuvant therapy for epiretinal membrane.

Acta Ophthalmol 2021 Apr 12. Epub 2021 Apr 12.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.

Purpose: To compare the efficacy of topical nepafenac 0.1% versus intravitreal triamcinolone acetonide (IVTA) at the conclusion of vitrectomy surgery versus no adjuvant therapy (NAT) in improving macular morphology post-operatively in patients undergoing vitrectomy for epiretinal membrane (ERM), as measured by optical coherence tomography (OCT) imaging and best-corrected visual acuity (BCVA).

Methods: Design: Prospective randomized clinical trial Setting: Multi-centre 80 patients scheduled to undergo vitrectomy surgery for idiopathic ERM were randomized to receive either IVTA (4 mg/0. Read More

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Rapid Morphological Restoration of Normal Foveal Contour After Spontaneous Epiretinal Membrane Separation from Retina in Eye with Macular Pseudohole: A Case Report.

Int Med Case Rep J 2021 31;14:211-214. Epub 2021 Mar 31.

Department of Ophthalmology, Akita University Graduate School of Medicine, Akita, Japan.

Purpose: This study aims to report a case of idiopathic epiretinal membrane (ERM) spontaneously separated from the retinal surface even in eyes with a macular pseudohole, which was immediately followed by resolution of visual deterioration and morphological findings.

Case Report: A 66-year-old man presented with visual deterioration and metamorphopsia in the right eye. An ERM with a macular pseudohole in the right eye was shown by fundus examinations and optical coherence tomography (OCT) images. Read More

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The Effect of the Idiopathic Epiretinal Membrane and Surgically Induced Posterior Vitreous Detachment on the Retinal Nerve Fiber Layer.

A Altun

J Ophthalmol 2020 18;2020:5217645. Epub 2020 Nov 18.

Bahçeşehir University, Department of Ophthalmology, Istanbul, Turkey.

Aim: To investigate the changes in the retinal nerve fiber layer (RNFL) following pars plana vitrectomy (PPV) with surgically induced posterior vitreous detachment (PVD) and idiopathic epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling.

Methods: Patients with unilateral ERM with vitreomacular traction were included in this prospective, randomized, and controlled clinical trial. The control group (Group 1) was formed with the nonoperated fellow eyes of the patients, and the study group (Group 2) was formed with the eyes that underwent PPV including idiopathic ERM and ILM peeling. Read More

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November 2020

Vital dyes in macular hole surgery.

Exp Ther Med 2021 May 22;21(5):527. Epub 2021 Mar 22.

Department of Ophthalmology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Currently, surgical techniques, such as internal limiting membrane peeling, are used widely for macular holes, macular puckers, epiretinal membranes, diabetic macular edema, retinal detachment, retinal vein occlusions, vitreomacular traction, optic pit maculopathy, and Terson syndrome. This study aimed to highlight any differences regarding visual acuity and ocular tomography coherence changes after staining the internal limiting membrane with dilutions of Brilliant Blue G vs. lutein/zeaxanthin-based dyes. Read More

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The extracellular matrix complexity of idiopathic epiretinal membranes and the bilaminar arrangement of the associated internal limiting membrane in the posterior retina.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 24. Epub 2021 Mar 24.

Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.

Purpose: To study the composition of the internal limiting membrane (ILM) of the retina, the extracellular matrix (ECM) of idiopathic epiretinal membranes (iERMs), and the relationships occurring between the two membranes.

Methods: Forty-six iERMs, 24 of them associated with the ILM, were collected and included in this study. The investigation has been carried out by immunofluorescence and confocal microscopy on glutaraldehyde- and osmium-fixed epon-embedded samples and on frozen samples. Read More

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Surgery for idiopathic epiretinal membrane.

Cochrane Database Syst Rev 2021 03 24;3:CD013297. Epub 2021 Mar 24.

UCL Institute of Ophthalmology, London, UK.

Background: Epiretinal membrane is an abnormal sheet of avascular fibrocellular tissue that develops on the inner surface of the retina. Epiretinal membrane can cause impairment of sight as a consequence of progressive distortion of retinal architecture.

Objectives: To determine the effects of surgery compared to no intervention for epiretinal membrane. Read More

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Prediction of Visual Prognosis after Epiretinal Membrane Surgery Using Regression Tree Analysis.

Semin Ophthalmol 2021 Mar 18:1-6. Epub 2021 Mar 18.

Hayashi Eye Hospital, Fukuoka, Japan.

: Confounding factors should be considered when predicting visual prognosis after epiretinal membrane (ERM) surgery. We aimed to predict visual acuity after ERM surgery using regression tree analysis.: We retrospectively reviewed 343 eyes of 343 patients who underwent vitrectomy for idiopathic ERM. Read More

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A novel quantitative analysis method for idiopathic epiretinal membrane.

PLoS One 2021 17;16(3):e0247192. Epub 2021 Mar 17.

Department of Biomedical Sciences, Humanitas University, Milan, Italy.

Purpose: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole.

Methods: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. Read More

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Comparison of the effect of air tamponade versus no tamponade after pars plana vitrectomy for idiopathic epiretinal membrane.

Sci Rep 2021 Mar 3;11(1):5082. Epub 2021 Mar 3.

Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-daero, Bupyeong-gu, Incheon, 21388, South Korea.

This study aimed to compare the surgical outcomes of pars plana vitrectomy (PPV) with and without air tamponade in patients with idiopathic epiretinal membrane (iERM). We prospectively enrolled 145 patients with iERM who underwent a 25-gauge transconjunctival sutureless PPV. Patients were assigned to either the air tamponade (air) group (79 eyes) or balanced salt solution (BSS; no tamponade) group (66 eyes). Read More

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Epiretinal membrane: A review.

Clin Exp Ophthalmol 2021 Apr 24;49(3):289-308. Epub 2021 Mar 24.

Save Sight Institute, Central Clinical School, Discipline of Ophthalmology and Eye Health, The University of Sydney, Sydney, New South Wales, Australia.

The prevalence of epiretinal membrane (ERM) is 7% to 11.8%, with increasing age being the most important risk factor. Although most ERM is idiopathic, common secondary causes include cataract surgery, retinal vascular disease, uveitis and retinal tears. Read More

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Prognostic factors of idiopathic epiretinal membrane surgery and evolution of alterations of the central cone bouquet.

Graefes Arch Clin Exp Ophthalmol 2021 Feb 24. Epub 2021 Feb 24.

Department of Ophthalmology, Intercommunal Hospital Center and Henri Mondor Hospital, Paris-Est Créteil University (UPEC, Paris XII University), 40 avenue de Verdun, 94000, Creteil, France.

Purpose: To describe the structural changes observed postoperatively in epiretinal membranes (ERM), in particular the alterations in the central cone bouquet (CB), and to identify prognostic factors that might predict postoperative outcome.

Methods: We included 125 eyes of 117 patients who underwent idiopathic ERM removal with at least a 6-month follow-up. For each patient, spectral-domain optical coherence tomography (SD-OCT) was performed and best-corrected visual acuity (BCVA) was measured, before and after surgery. Read More

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February 2021

Functional and Morphological Results of Epiretinal Membrane Surgery in Idiopathic versus Diabetic Epiretinal Membranes.

Semin Ophthalmol 2021 Feb 22:1-7. Epub 2021 Feb 22.

Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Ophthalmology, University of Health Sciences , Istanbul, Turkey.

: Idiopathic and diabetic epiretinal membranes (ERM) are different in terms of pathophysiology, etiology, and macular morphology, and thus might respond to surgical treatment differently. We aimed to compare the surgical results of two groups. : Retrospective case series study of 71 eyes of 66 patients who underwent pars plana vitrectomy (PPV) due to idiopathic or diabetic ERM with at least 1-year follow-up. Read More

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February 2021

Review of de novo uveitis in older adults presenting to a large tertiary centre.

Br J Ophthalmol 2021 Feb 17. Epub 2021 Feb 17.

Ophthalmology, Greenlane Clinical Centre, Auckland, New Zealand.

Background/aims: The primary aim of this study was to describe the causes of de novo uveitis in individuals 60 years and older. Secondary objectives were to determine the incidence of intraocular lymphoma and the clinical predictors of lymphoma.

Methods: Retrospective chart review of all subjects presenting to the uveitis service at Auckland District Health Board (Auckland, New Zealand) between January 2006 and October 2020 RESULTS: 686 subjects (900 eyes) were aged ≥60 years at first presentation with uveitis, representing 23. Read More

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February 2021

Postoperative outcomes of idiopathic epiretinal membrane associated with foveoschisis.

Br J Ophthalmol 2021 Feb 17. Epub 2021 Feb 17.

Université de Paris, Ophthalmology Department, AP-HP, Hôpital Lariboisière, F-75010, Paris, France

Aims: To analyse the prevalence and postoperative outcomes of a particular form of epiretinal membrane (ERM) with foveoschisis-like stretched hyporeflective spaces in emmetropic eyes.

Methods: A retrospective study of all consecutive eyes operated for primary ERM over a 46-month period was conducted. The presence of foveoschisis-like stretched hyporeflective spaces was assessed on the preoperative optical coherence tomography B-scan in all eyes. Read More

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February 2021

Biomarkers of Neurodegeneration and Precision Therapy in Retinal Disease.

Front Pharmacol 2020 18;11:601647. Epub 2021 Jan 18.

Ophthalmology Operative Complex Unit, University Campus Bio-Medico, Rome, Italy.

Vision-threatening retinal diseases affect millions of people worldwide, representing an important public health issue (high social cost) for both technologically advanced and new-industrialized countries. Overall RD group comprises the retinitis pigmentosa, the age-related macular degeneration (AMD), the diabetic retinopathy (DR), and idiopathic epiretinal membrane formation. Endocrine, metabolic, and even lifestyles risk factors have been reported for these age-linked conditions that represent a "public priority" also in this COVID-19 emergency. Read More

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January 2021

The predictive value of ectopic inner retinal layer staging scheme for idiopathic epiretinal membrane: surgical results at 12 months.

Eye (Lond) 2021 Feb 9. Epub 2021 Feb 9.

Bursa Retina Eye Hospital, Bursa, Turkey.

Background/objectives: To assess the effect of ectopic inner foveal layers (EIFL) based staging scheme, foveal avascular zone (FAZ) alterations and other microstructural optical coherence tomography (OCT) findings on visual function for patients undergoing idiopathic epiretinal membrane (iERM) surgery.

Subjects/methods: In this retrospective study, patients who underwent 27 G pars plana vitrectomy (PPV) for idiopathic ERM with a minimum follow-up of 12 months were included. Preoperative and postoperative OCT scans, FAZ area measurements on en face OCT angiography images and mean retinal sensitivity (MRS) using microperimetry were recorded in all cases. Read More

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February 2021

Optical coherence tomography biomarkers as predictive factors for postoperative visual acuity in patients with epiretinal membrane treated with vitrectomy.

Oman J Ophthalmol 2020 Sep-Dec;13(3):136-140. Epub 2020 Nov 2.

2nd Department of Ophthalmology, University of Athens, Athens, Greece.

Background: The purpose of this retrospective study was to evaluate potential predictive factors of postoperative visual outcome in patients with idiopathic epiretinal membrane (iERM), treated with pars plana vitrectomy (PPV).

Methods: Participants in the study were 46 patients diagnosed with iERM, who underwent PPV. Best-corrected visual acuity measurement and spectral domain-optical coherence tomography (OCT) were performed at baseline (preoperatively), and at months 6 and 12 postoperatively. Read More

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November 2020

The visual outcomes of idiopathic epiretinal membrane removal in eyes with ectopic inner foveal layers and preserved macular segmentation.

Graefes Arch Clin Exp Ophthalmol 2021 Feb 2. Epub 2021 Feb 2.

Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy.

Purpose: To analyze the functional impact of ectopic inner foveal layers (EIFL), along with other clinical and optical coherence tomography biomarkers, on patients with epiretinal membrane (ERM) and preserved foveal layers' segmentation undergoing ERM removal.

Methods: Retrospective review of consecutive patients with ERM who underwent pars plana vitrectomy with ERM peeling from December 2018 to December 2019. Baseline factors including age, gender, lens status, phacoemulsification at the time of surgery, tamponade agent, dye used for ERM and internal limiting membrane (ILM) enhancement, ILM peeling, best-corrected visual acuity (BCVA) and central macular thickness (CMT), presence and thickness of EIFL, thickness of outer nuclear layer (ONL), presence of a cotton ball, subfoveal state of photoreceptors, and presence of cystoid macular edema were included in a multivariable model having the BCVA at 12 months as the main outcome. Read More

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February 2021

Wide-based foveal pit: a predisposition to idiopathic epiretinal membrane.

Graefes Arch Clin Exp Ophthalmol 2021 Feb 2. Epub 2021 Feb 2.

Department of Ophthalmology, National Taiwan University Hospital, 7 Zhongshan S. Rd., Zhongzheng Dist., Taipei, 10002, Taiwan.

Purpose: To report the anatomical characteristics of wide-based foveal pit and its possible associations with macular diseases.

Methods: Wide-based foveal pit was defined as a foveal base width (FBW) larger than the mean value plus one standard deviation of the normal population. Eyes with a wide-based foveal pit were retrospectively collected as the study group, and age- and sex-matched subjects with a normal FBW were recruited as the control group. Read More

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February 2021

Temporal changes of parafoveal microvasculature after epiretinal membrane surgery: an optical coherence tomography angiography study.

Retina 2021 Jan 27. Epub 2021 Jan 27.

Departments of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea Departments of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Purpose: To investigate whether the parafoveal capillary architecture predicts clinical course and visual outcomes after ERM surgery.

Methods: A total of 71 eyes of 71 patients treated with vitrectomy for idiopathic ERM were enrolled. The parafoveal capillary displacement and fractal geometries were compared according to the stage of ERM. Read More

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January 2021

[Prediction of postoperative visual acuity in cataract patients with idiopathic macular epiretinal membrane by hand-held retinal optometer and optical coherence tomography].

Nan Fang Yi Ke Da Xue Xue Bao 2021 Jan;41(1):123-127

Department of Ophthalmology, Guangdong Second Provincial People's Hospital, Guangzhou 510310, China.

Objective: To investigate the value of hand-held retinal optometer and optical coherence tomography (OCT) in predicting postoperative visual acuity in patients with age-related cataract and idiopathic macular epiretinal membrane.

Methods: We retrospectively analyzed the data of patients undergoing phacoemulsification combined with intraocular lens implantation for age-related cataract in our hospital from January, 2019 to April, 2020.Preoperative examination detected idiopathic macular epiretinal membrane in 45 of the patients (52 eyes) with lens opacity grade C2N2P1 according to LOCSⅡ lens opacity classification criteria. Read More

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January 2021

Epiretinal membrane vitrectomy: outcomes with or without cataract surgery and a novel prognostic factor for cystoid macular edema.

Graefes Arch Clin Exp Ophthalmol 2021 Jan 25. Epub 2021 Jan 25.

Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Largo do Prof. Abel Salazar, 4099-001, Porto, Portugal.

Purpose: To assess the outcomes of vitrectomy with or without cataract surgery for the treatment of idiopathic ERM in phakic eyes and evaluate predictors of functional and anatomical outcomes.

Methods: Retrospective cohort of consecutive phakic ERM eyes distributed in three groups: a) combined (phacovitrectomy) group, b) PPV-only group, and c) consecutive group (PPV followed by cataract surgery). Main outcomes were final visual acuity (VA) and cystoid macular edema (CME) occurrence. Read More

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January 2021

Anatomical and Functional Recovery Kinetics After Epiretinal Membrane Removal.

Clin Ophthalmol 2021 15;15:175-181. Epub 2021 Jan 15.

Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

Purpose: To investigate the nature of anatomical and functional recovery kinetics after epiretinal membrane (ERM) removal.

Methods: The records of 42 patients (45 eyes) with idiopathic ERM treated with pars plana vitrectomy and surgical peeling of the ERM performed by a single surgeon at Massachusetts Eye and Ear between 2012 and 2017 were retrospectively reviewed. Outcome measures included spectral domain optical coherence tomography-measured central macular thickness (CMT) pre-operatively and at post-operative day 1, week 1, months 1, 3, 6, 12 and 24 as well as best-corrected visual acuity (BCVA). Read More

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January 2021

With or without internal limiting membrane peeling during idiopathic epiretinal membrane surgery: A meta-analysis.

PLoS One 2021 19;16(1):e0245459. Epub 2021 Jan 19.

Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.

Background: Although previously published meta-analyses have compared the surgical effects between the methods of Idiopathic epiretinal membrane (iERM) removal with or without ILM peeling, they did not reach an agreement.

Purpose: We aimed to provide more evidence for the treatment of iERM and whether additional ILM peeling was better or not by analyzing more updated studies and randomized control trials (RCTs).

Method: The search was conducted in Pubmed, Embase, Cochrane Library, Web of Science and Open Grey without language limitation and the studies included were from inception to December 2019. Read More

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January 2021

Correlation between tangential distortion of the outer retinal layer and metamorphopsia in patients with epiretinal membrane.

Graefes Arch Clin Exp Ophthalmol 2021 Jan 16. Epub 2021 Jan 16.

Department of Ophthalmology, Kobe City Eye Hospital, 2-1-8 Minatojima Minamimachi, Chuo-ku, Kobe-shi, Hyogo, 650-0047, Japan.

Purpose: To evaluate tangential morphological changes in the outer retina and assess their correlation with the degree of metamorphopsia in patients with idiopathic epiretinal membrane (ERM).

Methods: This retrospective study included patients with idiopathic ERM who underwent vitrectomy between January 2018 and December 2019. We evaluated the preoperative examination results. Read More

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January 2021

Assessment of Macular Function Following Internal Limiting Membrane Peeling With ILM Blue®.

Cureus 2020 Dec 3;12(12):e11873. Epub 2020 Dec 3.

Ophthalmology, University Eye Hospital Tübingen, Tübingen, DEU.

Purpose To evaluate clinical outcome after surgery of idiopathic epiretinal membranes (ERM) with internal limiting membrane (ILM) peeling using a commercial combination of Brilliant blue G (BBG, 0.25 mg/ml) with 4% polyethylene glycol (PEG). Methods It was a prospective, single-center study. Read More

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December 2020

Assessment of macular microvasculature features before and after vitrectomy in the idiopathic macular epiretinal membrane using a grading system: An optical coherence tomography angiography study.

Acta Ophthalmol 2021 Jan 10. Epub 2021 Jan 10.

Department of Retina Center, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, China.

Purpose: To evaluate pre- and postoperative microvasculature features in eyes with different idiopathic macular epiretinal membrane (iERM) classifications using optical coherence tomography angiography (OCTA).

Methods: In this retrospective study, 100 eyes with iERM were enrolled; 62 eyes underwent pars plana vitrectomy (PPV). All iERM eyes were evaluated and graded using optical coherence tomography (OCT). Read More

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January 2021

Spontaneous Conversion of Lamellar Macular Holes to Full-Thickness Macular Holes: Clinical Features and Surgical Outcomes.

Ophthalmol Retina 2021 Jan 5. Epub 2021 Jan 5.

Department of Ophthalmology, Palo Alto Medical Foundation, Palo Alto, California. Electronic address:

Purpose: To describe the clinical features and surgical outcomes of patients experiencing a spontaneous conversion of a lamellar macular hole (LMH) to a full-thickness macular hole (FTMH).

Design: Retrospective, multicenter, observational case series.

Participants: Patients with LMH who experienced a spontaneous conversion to FTMH and underwent FTMH surgery. Read More

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January 2021