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Ultrastructural Alterations of Grafted Corneal Buttons: The Anatomic Basis for Stromal Peeling along a Natural Plane of Separation.

Am J Ophthalmol 2021 Jun 9. Epub 2021 Jun 9.

University of Ferrara, Department of Translational Medicine, Ferrara, Italy; Ospedali Privati Forlì "Villa Igea", Department of Ophthalmology, Forlì, Italy; Istituto Internazionale per la Ricerca e Formazione in Oftalmologia (IRFO), Forlì, Italy.

Purpose: To examine the ultrastructure of the natural plane of separation in grafted corneas and evaluate the outcomes of stromal peeling.

Design: Interventional case series METHODS: In this multicenter study, stromal peeling was attempted in 96 consecutive eyes with unsatisfactory vision following penetrating keratoplasty (PK) for keratoconus(n=79), herpetic keratitis(n=11) and granular dystrophy(n=6). Stromal exchange was performed by: 1) 9mm partial-thickness trephination; 2) creation of a corneal flap across the PK wound; 3) opening of the stromal component of the PK wound until a smooth, translucent natural plane was identified; 4) severing the attachment of the PK scar; 5) stromal peeling along the identified plane; 6) suturing of donor lamella. Read More

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Description of the Metacercaria of Cardiocephaloides sp. (Digenea, Diplostomoidea), Newly Recorded from the Brain of Gangetic Leaffish (Nandus nandus) and Its Genetic Characterization in India.

Acta Parasitol 2021 Jun 12. Epub 2021 Jun 12.

Molecular Taxonomy Laboratory, Department of Zoology, Chaudhary Charan Singh University, Meerut, 250004, UP, India.

Purpose: Cardiocephaloides comprises strigeid trematodes that represent a small genus. In this study, metacercaria identified as Cardiocephaloides sp. was collected from the Gangetic leaffish Nandus nandus from the Ganga River at Bairaj, Bijnor (29º01'N, 77º45'E) in the state of Uttar Pradesh (U. Read More

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Silencing of transcription factor E93 inhibits adult morphogenesis and disrupts cuticle, wing and ovary development in Locusta migratoria.

Insect Sci 2021 Jun 11. Epub 2021 Jun 11.

Research Institute of Applied Biology, Shanxi University, Taiyuan, China.

Ecdysone-induced protein 93F (E93) plays important roles during the metamorphosis process in insects. In this study, a cDNA of the LmE93 gene was identified from the transcriptome of Locusta migratoria, which consists of the 3378-nucleotide open-reading frame (ORF) and encodes 1125 amino acids with helix-turn-helix (HTH) motifs. Reverse transcription quantitative polymerase chain reaction analysis revealed that LmE93 was highest expressed in ovary. Read More

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Sinonasal adenocarcinoma: A population-based analysis of demographic and socioeconomic disparities.

Head Neck 2021 Jun 12. Epub 2021 Jun 12.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background: Sinonasal adenocarcinoma (SNAC) is a rare tumor. The impact of health disparities on survival, stage at presentation, and utilization of surgery is not well understood in patients with SNAC.

Methods: The Surveillance, Epidemiology, and End Results database was queried for cases of SNAC from 1973 to 2015. Read More

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Anterior chamber angle features in primary congenital glaucoma infants using hand-held anterior segment-oct.

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Faculty of Medicine, Ophthalmology department, Cairo University, Cairo, Egypt.

Purpose: To describe anterior chamber angle (ACA) structures and parameters in primary congenital glaucoma (PCG) and normal infant eyes, using Hand-held anterior segment optical coherence tomography (HH AS-OCT), as an in-office, non-contact technique.

Methods: Normal and PCG-infants <24 months were examined, using HH AS-OCT (RTVue RT- 100, Optovue Inc., Fremont, CA). Read More

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The tracheal system in the stick insect prothorax and prothoracic legs: Homologies to orthoptera and relations to mechanosensory functions.

Johannes Strauß

Arthropod Struct Dev 2021 Jun 8;63:101074. Epub 2021 Jun 8.

AG Integrative Sensory Physiology, Institute for Animal Physiology, Justus-Liebig-Universität Gießen, Gießen, Germany; Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus Liebig University Gießen, Germany. Electronic address:

Arthropod respiration depends on the tracheal system running from spiracles at the body surface through the body and appendages. Here, three species of stick insects (Carausius morosus, Ramulus artemis, Sipyloidea sipylus) are investigated for the tracheae in the prothorax and foreleg. The origin of the tracheae from the mesothoracic spiracle that enter the foreleg is identified: five tracheae originate from the mesothoracic spiracle, of which two enter the foreleg (supraventral trachea, trachea pedalis anterior). Read More

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Impact of Opioid Prescribing Guidelines on Postoperative Opioid Prescriptions Following Elective Spine Surgery: Results From an Institutional Quality Improvement Initiative.

Neurosurgery 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background: With a dramatic rise in prescription opioid use, it is imperative to review postsurgical prescribing patterns given their contributions to the opioid epidemic.

Objective: To evaluate the impact of departmental postoperative prescribing guidelines on opioid prescriptions following elective spine surgery.

Methods: Patients undergoing elective cervical or lumbar spine surgery between 2017 and 2018 were identified. Read More

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Spatial relationship between the pulmonary trunk and the left coronaries: Systematic risk assessment based on automated three-dimensional distance measurements.

Heart Rhythm O2 2020 Apr 27;1(1):14-20. Epub 2020 Apr 27.

Informatics for Life, Heidelberg, Germany.

Background: Catheter ablation of right ventricular outflow tract ventricular arrhythmias from above the pulmonary valve is being increasingly reported.

Objective: The purpose of this study was to systematically analyze the spatial relationship between the pulmonary trunk and the left coronaries.

Methods: Contrast-enhanced computed tomographic scans from 58 patients were analyzed. Read More

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A case of Wolff-Parkinson-White syndrome in which two-dimensional speckle-tracking echocardiography was useful for identifying the location of the accessory atrioventricular pathway.

Eur Heart J Case Rep 2021 Mar 4;5(3):ytab078. Epub 2021 Mar 4.

Division of Cardiology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo 693-8501, Japan.

Background: In Wolff-Parkinson-White (WPW) syndrome, accessory atrioventricular pathways (AP) result in abnormal pre-excitation around the atrioventricular annuli and produce a dyssynchronous contraction of cardiac chambers. Identification of the AP affects the outcome of catheter ablation.

Case Summary: We report a case of WPW syndrome and paroxysmal atrial fibrillation in a 65-year-old man. Read More

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Redefining postmastectomy radiation contouring in the era of immediate breast reconstruction: An accurate assessment of local recurrence risk.

Clin Transl Radiat Oncol 2021 Jul 6;29:33-39. Epub 2021 May 6.

Dept. Oncology, London Regional Cancer Program, London, ON, Canada.

Introduction: Most studies report post-mastectomy local recurrences as chest wall recurrences without clarifying whether the recurrence is in the subcutaneous tissue, muscle or underlying rib. Post-mastectomy chest wall radiation is recommended in patients at increased risk of locoregional recurrence. Chest wall radiation-related fibrosis has become an important clinical consideration in the era of immediate implant-based breast reconstruction. Read More

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Coronary Artery Fistula Aneurysm: Pathological Analysis After Surgery.

Cureus 2021 May 8;13(5):e14903. Epub 2021 May 8.

Cardiology, Kawasaki Municipal Ida Hospital, Kawasaki, JPN.

An asymptomatic 75-year-old woman was identified with a 40-mm-sized, round-shaped lesion beside the pulmonary artery on computed tomography (CT). Coronary angiography showed a coronary artery fistula (CAF) with an aneurysm branching from the left anterior descending artery toward the pulmonary artery. The CAF aneurysm (CAFA) was resected and coronary artery bypass graft surgery using the left internal thoracic artery was performed successfully. Read More

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High false-negative rate of the anterior spinal artery by intercostobronchial trunk arteriography alone compared to CT during arteriography.

Br J Radiol 2021 Jun 11:20210402. Epub 2021 Jun 11.

Department of Respiratory medicine, Teine Keijinkai Hospital, Sapporo, Japan.

Objectives: This study aimed to assess the frequencies of the anterior spinal arteries identified by CT during arteriography (CTA) and arteriography alone.

Methods: This retrospective study included 137 vessels in 83 patients who performed both bronchial arteriography and CTA and categorized them into three groups based on the catheter tip locations: intercostobronchial trunk (ICBT), bronchial artery (BA), and intercostal artery (ICA). The frequencies of anterior spinal artery identified by CTA and arteriography alone were compared for each group. Read More

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Feasibility and Outcomes of Multivisceral Resection in Locally Advanced Colorectal Cancer: Experience of a Tertiary Cancer Center in North-East India.

Ann Coloproctol 2021 Jun 10. Epub 2021 Jun 10.

Department of Surgical Oncology, Dr. B. Borooah Cancer Institute, Guwahati, India.

Purpose: Locally advanced colorectal cancer may require an en bloc resection of surrounding organs or structures to achieve complete tumor removal. This decision must weigh the risk of complications of multivisceral resection against the potential survival benefit. The purpose of this study is to review a single-center experience of feasibility of en bloc multivisceral resections for locally advanced colorectal carcinoma and to examine the effect of surgical experience on immediate outcome and rate of R0 resections. Read More

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Efficacy of a robotic stapler on symptomatic anastomotic leakage in robotic low anterior resection for rectal cancer.

Surg Today 2021 Jun 10. Epub 2021 Jun 10.

Division of Colon and Rectal Surgery, Shizuoka Cancer Center, 1007 ShimonagakuboNagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.

Purpose: Clinical evidence demonstrating risk factors for anastomotic leakage including robotic staplers has remained limited, even though the use of robotic surgery has increased substantially. The purpose of this study was to evaluate the effects of robotic staplers on symptomatic anastomotic leakage in robotic low anterior resection for rectal cancer.

Methods: A total of 427 consecutive patients with primary rectal cancer who underwent robotic low anterior resection without diverting stoma were investigated retrospectively. Read More

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Stride-to-Stride Variability of the Center of Mass in Male Trained Runners After an Exhaustive Run: A Three Dimensional Movement Variability Analysis With a Subject-Specific Anthropometric Model.

Front Sports Act Living 2021 24;3:665500. Epub 2021 May 24.

BioMotion Center, Institute of Sports and Sports Science (IfSS), Karlsruhe Institute of Technology, Karlsruhe, Germany.

The motion of the human body can be described by the motion of its center of mass (CoM). Since the trajectory of the CoM is a crucial variable during running, one can assume that trained runners would try to keep their CoM trajectory constant from stride to stride. However, when exposed to fatigue, runners might have to adapt certain biomechanical parameters. Read More

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Cardiac Involvement in Facioscapulohumeral Muscular Dystrophy (FSHD).

Front Neurol 2021 24;12:668180. Epub 2021 May 24.

Department of Neurology, Mayo Clinic, Rochester, MN, United States.

Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common muscular dystrophies and predominantly affects facial and shoulder girdle muscles. Previous case reports and cohort studies identified minor cardiac abnormalities in FSHD patients, but their nature and frequency remain incompletely characterized. We reviewed cardiac, neurological and genetic findings of 104 patients with genetically confirmed FSHD. Read More

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A bronchopulmonary artery fistula in a horse.

J Vet Med Sci 2021 Jun 10. Epub 2021 Jun 10.

Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University.

A 24-year-old, Thoroughbred gelding presented with difficulty breathing for a few days and intermittent nose bleeding before dying. At necropsy, the bronchoesophageal artery and the bronchial artery that flowed into the left anterior lobe were tortuous and dilated, and it was found that dilated tortuous branches of the bronchial artery ran over the dorsal and ventral surfaces of the left anterior lobe. Histopathologically, an anastomosis between a muscular artery and an elastic artery were demonstrated, which were identified as bronchial and pulmonary arteries, respectively. Read More

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Diffusion-weighted imaging reveals distinct patterns of cytotoxic edema in patients with subdural hematomas.

J Neurotrauma 2021 Jun 9. Epub 2021 Jun 9.

University of Cincinnati, 2514, Neurology and Rehabilitation Medicine, Cincinnati, Ohio, United States;

Subdural hematomas (SDHs) are increasingly common and can cause ischemic brain injury. Prior work has suggested that this is driven largely by vascular compression from herniation, although this work was done prior to the era of magnetic resonance imaging (MRI). We thus sought to study SDH-related ischemic brain injury by looking at patterns of cytotoxic edema on diffusion-weighted MRI. Read More

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Oral Myofunctional and Articulation Disorders in Children with Malocclusions: A Systematic Review.

Folia Phoniatr Logop 2021 Jun 9:1-16. Epub 2021 Jun 9.

Department of Rehabilitation Sciences, Language, and Hearing Sciences, Ghent University, Ghent, Belgium.

Background: Relationships between malocclusion and orofacial myofunctional disorders (OMD), as well as malocclusions and articulation disorders (AD) have been described, though the exact relationships remain unclear. Given the high prevalence of these disorders in children, more clarity is needed.

Summary: The purpose of this study was to determine the association between OMD (specifically, bruxism, deviate swallowing, caudal resting tongue posture, and biting habits), AD, and malocclusions in children and adolescents aged between 3 and 18 years. Read More

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Use of Cryotherapy for Managing Epistaxis in the First Aid Setting: A Scoping Review.

Cureus 2021 May 4;13(5):e14832. Epub 2021 May 4.

Australian Resuscitation Council, Australian and New Zealand Committee on Resuscitation (ANZCOR) Evidence Reviewer, East Melbourne, AUS.

Epistaxis, or nosebleed, is bleeding from the nostril(s), nasal cavity, or nasopharynx. Anterior nasal bleeding is the most common location for spontaneous nontraumatic epistaxis and is commonly treated with manual compression to the nasal alae. Cryotherapy is also routinely recommended in conjunction with manual compression in the first aid and ED setting. Read More

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Newborn twins with perineal grooves.

SAGE Open Med Case Rep 2021 30;9:2050313X211020222. Epub 2021 May 30.

Department of Pediatrics, Wake Forest Baptist Medical Center, Wake Forest University Health Sciences, Winston-Salem, NC, USA.

Twin girls born at term were noted to have hypertrophic and erythematous mucosal sulci extending from the posterior vaginal fourchette to the anterior ridge of the anus on their newborn exams. Pregnancy was complicated by gestational hypertension and dichorionic diamniotic twin pregnancy. No known traumas were sustained during delivery to either twin. Read More

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Reconstruction of the external auditory canal: The tragal flap revisited and review of contemporary reconstructive techniques.

Am J Otolaryngol 2021 May 31;42(6):103094. Epub 2021 May 31.

Thyroid, Head, and Neck Cancer (THANC) Foundation, 10 Union Square East, Suite 5B, New York, NY 10003, USA; Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, 10 Union Square East, Suite 5B, New York, NY 10003, USA.

Background: Primary malignancies arising in the external auditory canal (EAC) are rare and usually are treated surgically. We review techniques to reconstruct the EAC following ablative surgery, and introduce a rarely utilized tragal skin flap which has particular advantages for reconstruction of limited anterior EAC defects.

Methods: The terms "tragal flap", "external auditory canal", "preauricular tragal flap", "reconstructive techniques" were searched on PubMed and Google Scholar. Read More

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Graft Failure, Revision ACLR, and Reoperation Rates After ACLR With Quadriceps Tendon Versus Hamstring Tendon Autografts: A Registry Study With Review of 475 Patients.

Am J Sports Med 2021 Jun 8:3635465211015172. Epub 2021 Jun 8.

Sports Orthopedic Research Center-Copenhagen (SORC-C), Department of Orthopedic Surgery, Copenhagen University Hospital Amager-Hvidovre, Denmark.

Background: It has been indicated that anterior cruciate ligament reconstruction (ACLR) with a quadriceps tendon (QT) graft has a higher risk of revision compared with ACLR performed with a hamstring tendon (HT) graft.

Purpose/hypothesis: To investigate whether ACLR with QT graft had a higher risk of graft failure, revision ACLR, or reoperation compared with HT graft in a high-volume center. We hypothesized that there would be no between-group differences. Read More

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The Potential of Closed-Loop Endovascular Neurostimulation as a Viable Therapeutic Approach for Drug Resistant Epilepsy: A Critical Review.

Artif Organs 2021 Jun 8. Epub 2021 Jun 8.

The Department of Neuroscience, Central Clinical School, Monash University, Department of Neurology, Alfred Health.

Over the last few decades, biomedical implants have successfully delivered therapeutic electrical stimulation to reduce the frequency and severity of seizures in people with drug-resistant epilepsy. However, neurostimulation approaches require invasive surgery to implant stimulating electrodes, and surgical, medical and hardware complications are not uncommon. An endovascular approach provides a potentially safer and less invasive surgical alternative. Read More

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Mapping of Vertical Femoral Neck Fractures in Young Patients Using Advanced 2 and 3-Dimensional Computed Tomography.

J Orthop Trauma 2021 Jun 5. Epub 2021 Jun 5.

Objective: To better describe the pathoanatomy of young patients' femoral neck fractures with the goal of improving surgeons' decisions for treatment including reduction and fixation.

Design: This is a retrospective study of patient records, plain radiographs, and the modern computed tomography scans to study the pathoanatomy of Pauwels II and III femoral neck fractures (coronal angle >30 degrees) in young adults.

Setting: One American College of Surgeons Level 1 trauma center. Read More

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Evaluation of critical shoulder angle and acromion index in patients with anterior shoulder instability and rotator cuff tear.

Acta Orthop Traumatol Turc 2021 May;55(3):220-226

Department of Radiology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey.

Objective: The aim of this study was to evaluate glenohumeral morphologic differences and their correlation between glenohumeral instability and rotator cuff pathology.

Methods: Two-hundred radiographs and 100 MRI scans of 100 patients in whom the diagnosis of Anterior Shoulder Instability (Anl) or Rotator Cuff Tear (RCT) was arthroscopically verified were retrospectively identified and included in the study. All the patients were categorized into two groups: 50 patients with Anl (23 female, 28 male; mean age = 29 ± 7. Read More

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In Situ Neurolysis of Ulnar Nerve for Patients With Failed Anterior Subcutaneous Transposition - A Case Series.

Oper Neurosurg (Hagerstown) 2021 Jun 7. Epub 2021 Jun 7.

Department of Orthopaedic Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea.

Background: Various surgical techniques have been attempted to treat patients with failed anterior subcutaneous transposition performed for cubital tunnel syndrome.

Objective: To analyze intraoperative findings of failed anterior subcutaneous transposition and to report the outcome of in Situ neurolysis of ulnar nerve.

Methods: Patients who, under diagnosis of failed anterior subcutaneous transposition of ulnar nerve, underwent in Situ neurolysis between 2001 and 2018 were included in this study. Read More

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Anatomical variant of physeal blood supply to the fibula.

BMJ Case Rep 2021 Jun 7;14(6). Epub 2021 Jun 7.

Plastic Surgery, Guy's and St Thomas' Hospitals NHS Trust, London, UK.

Vascularised epiphysial fibula bone transfers in the paediatric population provides a solution to growth suppression in extremity reconstruction. We report a case of an anatomical variant to the epiphysial blood supply that has never been reported in literature. A 6-year-old girl underwent a free vascularised fibula flap for reconstruction of her right humerous following osteosarcoma resection. Read More

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Prevalence of carotid web in a French cohort of cryptogenic stroke.

J Neurol Sci 2021 May 28;427:117513. Epub 2021 May 28.

Unité Neurovasculaire, Département de Neurologie, Hôpital Gui de Chauliac, Montpellier, France. Electronic address:

Background And Purpose: Carotid webs (CaW) may be an under-recognized cause of anterior circulation cryptogenic ischemic stroke (ACIS). Prevalence is still unknown in European patients with ACIS.

Objective: To evaluate the prevalence of CaW in ACIS and describe patients with CaW phenotype in a cohort of patients from a French stroke center. Read More

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The relationship between injury-related fear and physical activity in people with a history of anterior cruciate ligament reconstruction.

Phys Ther Sport 2021 May 30;50:201-205. Epub 2021 May 30.

Department of Athletic Training and Clinical Nutrition, University of Kentucky, 900 South Limestone Street, Lexington, KY, 40536, USA. Electronic address:

Objective: The objective of this study was to examine the relationship between fear-avoidance beliefs and physical activity (PA) in people with a history of anterior cruciate ligament reconstruction (ACLR).

Design: Modified cross-sectional.

Setting: Research laboratory Participants: A total of 19 participants with a history of unilateral ACLR. Read More

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