PLoS One 2018 1;13(2):e0190986. Epub 2018 Feb 1.
Guangzhou KingMed Center for Clinical Laboratory, Guangzhou, China.
Inadequate discriminatory power to distinguish between L. pneumophila isolates, especially those belonging to disease-related prevalent sequence types (STs) such as ST1, ST36 and ST47, is an issue of SBT scheme. In this study, we developed a multilocus sequence typing (MLST) scheme based on two non-virulence loci (trpA, cca) and three virulence loci (icmK, lspE, lssD), to genotype 110 L. Read More