5,929 results match your criteria hyponatremia case


Hyponatraemia in Adult Patients with Pneumonia in a Medical College Hospital of Bangladesh.

Mymensingh Med J 2021 Apr;30(2):267-273

Dr Mohammed Amdad Ullah Khan, Assistant Professor, Department of Medicine, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

Pneumonia is an acute on chronic infection involving the pulmonary parenchyma. Most cases are caused by microbial pathogens usually bacteria or viruses and less often fungi or parasites. Hyponatraemia on admission is associated with greater risk of death and increased length of hospital stays. Read More

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Type 3 antenatal Bartter syndrome presenting with mild polyuria.

BMJ Case Rep 2021 Apr 7;14(4). Epub 2021 Apr 7.

Department of Pediatrics, Dokkyo Medical University, Shimotsuga-gun, Tochigi, Japan.

Bartter syndrome (BS) is a well-recognised inherited tubular dysfunction that causes polyuria, metabolic alkalosis and hypokalaemia. Among BS cases, antenatal/neonatal BS (ABS) usually shows distinct polyhydramnios prenatally and presents features of BS in the early neonatal period. We encountered a premature infant with type 3 ABS presenting with mild polyuria and discuss the pathogenesis of mild polyuria in type 3 ABS. Read More

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Characteristics of Children With Kawasaki Disease-Like Signs in COVID-19 Pandemic: A Systematic Review.

Front Pediatr 2021 18;9:625377. Epub 2021 Mar 18.

Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.

Recent studies have shown that several children diagnosed with COVID-19 have developed Kawasaki Disease (KD)-like symptoms. This systematic review aims to assess the demographic, laboratory, and clinical characteristics of children with KD-like syndrome during the COVID-19 pandemic and evaluate efficacy of treatments and patients' outcome. A comprehensive search was carried out systematically through PubMed, Scopus, and Web of Science (WoS), medRxiv, and bioRxiv by two reviewers independently for all studies or preprints data on the demographic, laboratory, and clinical characteristics of children with K. Read More

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New Onset Diabetes Mellitus Complicated by Hypertriglyceridemia-Induced Pancreatitis.

Cureus 2021 Feb 26;13(2):e13569. Epub 2021 Feb 26.

Internal Medicine, The Chicago Medical School Internal Medicine Residency Program at Northwestern McHenry Hospital, McHenry, USA.

There is an increasing prevalence of type 2 diabetes mellitus (DM) among adolescents due to obesity. Diabetes can cause hypertriglyceridemia, defined as triglyceride (TG) levels above 150 mg/dl, leading to severe complications, including cardiovascular events, fatty liver disease, and acute pancreatitis. We present a case of acute pancreatitis manifested by both hypertriglyceridemia and new-onset DM. Read More

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February 2021

A systematic review of stereotactic radiofrequency ablation for hypothalamic hamartomas.

J Neurol Sci 2021 Mar 27;424:117428. Epub 2021 Mar 27.

Departments of Neurosurgery, Los Angeles (UCLA), Los Angeles, CA, United States; Departments of Radiation Oncology, Los Angeles (UCLA), Los Angeles, CA, United States; Departments of Head and Neck Surgery, Los Angeles (UCLA), Los Angeles, CA, United States; Jonsson Comprehensive Cancer Center, Los Angeles (UCLA), Los Angeles, CA, United States; Los Angeles Biomedical Research Institute, Los Angeles (UCLA), Los Angeles, CA, United States; Harbor-UCLA Medical Center, Los Angeles (UCLA), Los Angeles, CA, United States; David Geffen School of Medicine, Los Angeles (UCLA), Los Angeles, CA, United States. Electronic address:

Background: The seizure activity associated with hypothalamic hamartomas (HHs) is refractory to medical management and surgical intervention is often required. Stereotactic Radiofrequency Ablation (SRFA) is a minimally invasive technique offering targeted lesion ablation with a reduced risk of complications.

Objective: Here, we review the current literature on the use of SRFA for HHs. Read More

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A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism.

Vet Sci 2021 Mar 7;8(3). Epub 2021 Mar 7.

Earth Animal Hospital, 4-3-43 Hokushin-cho, Kitami, Hokkaido 090-0052, Japan.

This report describes the first clinical case, to our knowledge, of a dog with polyglandular deficiency syndrome with diabetes mellitus and hypoadrenocorticism. A six-year-old female Cavalier King Charles Spaniel presented with a history of lethargy and appetite loss. The dog was diagnosed with diabetic ketoacidosis based on hyperglycemia and renal glucose and ketone body loss. Read More

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[Hyperosmolar Hyperglycemic State (HHS) with extreme hyperglycemia and hyperglycemia-induced hyponatremia in a patient with previously known diabetes mellitus type 2].

Lakartidningen 2021 03 26;118. Epub 2021 Mar 26.

överläkare, VO internmedicin, Visby lasarett.

This case report covers a patient presenting unconscious to the emergency department with a serum glucose level of 125.6 mmol/L and an associated hyperglycemia-induced hyponatremia with a sodium level of 101 mmol/L. The glucose level is, to our knowledge, one of the most extreme values described in medical literature. Read More

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Herbal Supplements: Can They Cause Hypomania?

Cureus 2021 Feb 21;13(2):e13476. Epub 2021 Feb 21.

Psychiatry, State University of New York Upstate Medical University, Syracuse, USA.

Herbal medication use is prevalent and increasing in the general population. A comprehensive review of complementary and alternative medicine use including herbal medications and supplements is often overlooked by physicians. Patients generally believe that all herbal products are safe without any side-effects. Read More

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February 2021

Secondary Pseudohypoaldosteronism Associated With Mild Hydronephrosis in a Newborn.

Cureus 2021 Feb 20;13(2):e13462. Epub 2021 Feb 20.

Department of Pediatrics, Saiseikai Kyoto Hospital, Kyoto, JPN.

Neonatal hyponatremia with hyperkalemia is a rare but potentially life-threatening occurrence. Aldosterone deficiency secondary to congenital adrenal hyperplasia (CAH) is often suspected in these cases, although it is not easy to accurately diagnose it initially. We report the case of a 12-day-old female infant presenting with poor sucking, hyperkalemia, and hyponatremia. Read More

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February 2021

Inappropriate Secretion of Antidiuretic Hormone after Pancreatoduodenectomy for Pancreatic Head Cancer: A Case Report and Literature Review.

Case Rep Oncol 2021 Jan-Apr;14(1):134-140. Epub 2021 Mar 1.

Department of Surgery, National Hospital Organization Higashihiroshima Medical Center, Higashihiroshima, Japan.

Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disease that leads to dilute hyponatremia through excessive secretion of antidiuretic hormone. SIADH has various causes, including ectopic ADH-producing tumors, drug properties, and can be idiopathic. But there have been very few reports of cases in which SIADH has developed after surgery for malignant tumors. Read More

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Early recognition of PIMS-TS: a single centre retrospective review.

BMJ Paediatr Open 2021 8;5(1):e001011. Epub 2021 Mar 8.

Paediatrics, North Middlesex University Hospital, London, UK.

Introduction: Research into paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) has focused on tertiary level management. This review reports on symptoms and investigations at presentation.

Methods: Single centre retrospective case note analysis of patients fulfilling PIMS-TS diagnostic criteria from March to May 2020 in a London district level university hospital. Read More

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Osmotic demyelination syndrome in patients with non-Hodgkin lymphoma: A case report and literature review.

Int J Neurosci 2021 Mar 25:1-6. Epub 2021 Mar 25.

Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.

Osmotic demyelination syndrome (ODS) is a non-inflammatory process of the central nervous system caused by extracellular osmotic changes, which leads to oligodendrocyte apoptosis and disruption of myelin sheaths, usually affecting patients with underlying systemic conditions that impose susceptibility to osmotic stress. Description of ODS in patients with non-Hodgkin lymphoma (NHL) is limited to a few case reports. Here, we report a 44-year-old man with NHL that had an incidental diagnosis of ODS. Read More

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Hyponatremia and Encephalopathy in a 55-Year-old Woman with Syndrome of Inappropriate Antidiuretic Hormone Secretion as an Isolated Presentation of SARS-CoV-2 Infection.

Am J Case Rep 2021 Mar 24;22:e930135. Epub 2021 Mar 24.

Department of Nephrology, Brookdale University Hospital Medical Center, Brooklyn, NY, USA.

BACKGROUND During the coronavirus disease 2019 (COVID-19) pandemic of 2020, varied presentations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. The present report is of a case of hyponatremia and encephalopathy due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) as the main presentation of SARS-CoV-2 infection in a 55-year-old woman. CASE REPORT A 55-year-old woman with type II diabetes mellitus presented with confusion and slurring of speech, with a temperature of 38. Read More

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Addison's Disease: A Diagnosis Easy to Overlook.

Cureus 2021 Feb 15;13(2):e13364. Epub 2021 Feb 15.

Endocrinology, Hospital de Braga, Braga, PRT.

Addison's disease is a rare and potentially life-threatening clinical condition that often presents with an insidious onset of nonspecific symptoms and signs, frequently resulting in a significant delay in diagnosis. Clinical presentation usually includes fatigue and electrolyte imbalance disorders such as hyponatremia. However, specific diagnostic features, such as hyperpigmentation, should raise clinical suspicion. Read More

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February 2021

Therapeutic hypothermia and outcome in hyponatraemic encephalopathy secondary to maternal water intoxication.

BMJ Case Rep 2021 Mar 17;14(3). Epub 2021 Mar 17.

Regional Neonatal Intensive Care Unit, St Michael's Hospital, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK

Misguided encouragement to consume large volumes of water during labour for pain relief results in dilutional hyponatraemia in mothers and their babies presenting with neurological dysfunction. We report three babies who were encephalopathic with seizures in the background of hyponatraemia secondary to maternal ingestion of large volumes of water and mild perinatal asphyxia. All babies underwent therapeutic hypothermia in addition to sodium supplementation with fluid restriction. Read More

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Prolonged Altered Mental Status in a Diabetic Hemodialysis Patient.

Cureus 2021 Feb 4;13(2):e13132. Epub 2021 Feb 4.

Internal Medicine/Nephrology, Metropolitan Hospital Center, New York Medical College, New York, USA.

Osmotic demyelination syndrome (ODS) is a demyelinating disorder of the central nervous system. It usually occurs with rapid correction of severe chronic hyponatremia. ODS is rarely seen as a complication of hyperglycemia. Read More

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February 2021

Pituitary tumor apoplexy associated with extrapontine myelinolysis during pregnancy: A case report.

Medicine (Baltimore) 2021 Mar;100(10):e25075

Department of Radiology.

Rationale: Pituitary tumor apoplexy (PTA) is a rare clinical syndrome which requires urgent diagnosis and treatment due to its life-threatening consequences. Management of undiagnosed pituitary tumor before pregnancy is a problem during pregnancy.

Patient Concerns: We reported a case with PTA which was not diagnosed before pregnancy presenting with vomiting associated with hyponatremia during the third trimester. Read More

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The Diagnosis and Management of Endocrine Side Effects of Immune Checkpoint Inhibitors.

Dtsch Arztebl Int 2021 Jun 11;118(Forthcoming). Epub 2021 Jun 11.

Background: The immunologically mediated side effects of immune checkpoint inhibitors (CPI) often involve the endocrine system as well, and they can even be fatal, as in the case of unrecognized hypophysitis. Distinguishing such side effects from tumor-related changes is often difficult, because their clinical features can be nonspecific.

Methods: This review is based on publications retrieved by a selective search in PubMed, with special attention to international recommendations. Read More

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The Value of Screening for Bicuspid Aortic Valve in First Degree Family Members.

Cureus 2021 Feb 7;13(2):e13201. Epub 2021 Feb 7.

Internal Medicine, McLaren Health Care, Michigan State University, Flint, USA.

A 54-year-old male with a history of hypertension, diabetes, and sleep apnea presented with a two-week history of dyspnea. The patient was hypoxic with bilateral leg edema. Initial workup showed elevated troponin at 0. Read More

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February 2021

Patient with Bartter syndrome in whom chronic potassium depletion was considered one of the causes of hyponatremia.

BMJ Case Rep 2021 Mar 10;14(3). Epub 2021 Mar 10.

Department of Internal Medicine, Shitennoji Hospital, Osaka, Japan

A 53-year-old man was admitted to our hospital because of general fatigue and disorientation. He had been diagnosed with Bartter syndrome in his teens and had been taking potassium preparations since then. However, his serum potassium concentration (K) remained persistently low. Read More

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Distinguishing cerebral salt wasting syndrome and syndrome of inappropriate ADH in a patient with traumatic brain injury.

BMJ Case Rep 2021 Mar 10;14(3). Epub 2021 Mar 10.

Department of Anaesthesia and Intensive Care, University College Cork, Cork, Ireland.

A previously healthy 48-year-old woman was referred to our intensive care unit (ICU) from a neurosurgical ward due to deterioration of her conscious level. She had a road traffic accident 6 days earlier. On admission to the hospital, a brain CT demonstrated subarachnoid haemorrhage which was considered not amenable to surgical intervention. Read More

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An Unusual Presentation of ST Elevation Myocardial Infarction Complicated with Cardiogenic Shock Due to Myxedema Coma: A Case Report.

Am J Case Rep 2021 Mar 10;22:e929573. Epub 2021 Mar 10.

Department of Cardiology, United Health Services Hospitals, Wilson Regional Medical Center, Johnson City, NY, USA.

BACKGROUND Myxedema coma is an endocrine emergency with a high mortality rate, defined as a severe hypothyroidism leading to hypotension, bradycardia, decreased mental status, hyponatremia, hypoglycemia, and cardiogenic shock. Although hypothyroidism and cardiac disease has been interlinked, ST elevation myocardial infarction in the setting of myxedema coma have not been reported previously. CASE REPORT We report the case of a 70-year-old man who presented to the Emergency Department with chest pain and confusion. Read More

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Duloxetine-induced hyponatraemia in a patient with hypocortisolaemia.

J Family Med Prim Care 2020 Dec 31;9(12):6282-6284. Epub 2020 Dec 31.

Department of Pharmacy, Kuwana City Medical Center, Kuwana, Japan.

Duloxetine-induced hyponatraemia is a known adverse effect that can lead to potentially life-threatening complications. In addition, hypocortisolaemia is associated with the development of hyponatraemia. Here, we report a case of severe hyponatraemia rapidly presenting after duloxetine treatment in a patient with hypocortisolaemia. Read More

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December 2020

Sweet Taste Dysgeusia in a Patient with Indapamide-Related Hyponatremia: Case Report and Review of the Literature.

Cureus 2021 Feb 2;13(2):e13079. Epub 2021 Feb 2.

Internal Medicine, Serviço de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, PRT.

Sweet taste dysgeusia is a rare symptom where patients experience all food as having a sweet taste. While its cause is still unknown, it has been increasingly reported in the setting of lung cancer and syndrome of inappropriate secretion of antidiuretic hormone-related hyponatremia. In this case report, we present what we believe to be the first case of sweet taste dysgeusia in a non-cancer context. Read More

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February 2021

[Central nervous system toxicity caused by bortezomib: five case reports and a review of literature].

Zhonghua Xue Ye Xue Za Zhi 2021 Jan;42(1):63-69

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.

To investigate the clinical features, diagnosis, and treatment of the central nervous system (CNS) toxicity caused by bortezomib. This study reports five new cases of CNS toxicity caused by bortezomib to elucidate its characteristics along with a review of the literature. CNS toxicity caused by bortezomib presents in three clinical forms: syndrome of inappropriate antidiuresis (SIAD) , posterior reversible encephalopathy syndrome (PRES) , and central fever, which is the most common clinical manifestation. Read More

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January 2021

Addison's disease with primary hypothyroidism in a case of visceral leishmaniasis and HIV coinfection.

BMJ Case Rep 2021 Mar 5;14(3). Epub 2021 Mar 5.

Department of Endocrinology and Medicine, Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences, Rohtak, India

A 41-year-old man presented with vomiting and loose stools. He had a history of long-term intermittent fever, generalised skin hyperpigmentation, dragging sensation in the left hypochondrium and unintentional weight loss. He was receiving combination antiretroviral therapy since 2010 for HIV infection. Read More

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Cotrimoxazole-induced hyperkalaemia in a patient with known hypoaldosteronism.

BMJ Case Rep 2021 Mar 4;14(3). Epub 2021 Mar 4.

Department of Diabetes and Endocrinology, Mater Dei Hospital, Msida, Malta.

A70-year-old man, with established hypoadrenalism due to a previous bilateral adrenalectomy, was admitted with recurrent episodes of postural dizziness and presyncope. He had been discharged from hospital 3 weeks earlier on a 1-month course of cotrimoxazole following a diagnosis of prostatitis. His electrolytes on admission showed new onset hyponatraemia and hyperkalaemia. Read More

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Successful Treatment with Percutaneous Balloon Kyphoplasty for Syndrome of Inappropriate Secretion of Antidiuretic Hormone Associated with Vertebral Compression Fracture: A Case Report.

Am J Case Rep 2021 Mar 4;22:e928055. Epub 2021 Mar 4.

Division of Community Medicine, Kanazawa Medical University Himi Municipal Hospital, Himi, Toyama, Japan.

BACKGROUND The etiology of syndrome of inappropriate antidiuretic hormone secretion (SIADH) is highly variable. With little evidence, much of the guidance and recommendations available for management are based on clinical judgement. Although percutaneous balloon kyphoplasty can effectively relieve the severe pain associated with osteoporotic vertebral compression fractures that do not respond to conventional treatments, the effect of balloon kyphoplasty on SIADH associated with vertebral compression fracture remains unknown. Read More

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Hyponatraemia due to hypothyroidism: a rare side effect from pomalidomide.

BMJ Case Rep 2021 Mar 2;14(3). Epub 2021 Mar 2.

Internal Medicine, Greater Baltimore Medical Center, Towson, Maryland, USA

Pomalidomide is an immunomodulatory drug used for relapsed and refractory multiple myeloma (RRMM). Hypothyroidism is an uncommon side effect of pomalidomide. We present a 70-year-old male patient with RRMM on daratumumab, pomalidomide and dexamethasone, who presented with 2 weeks of fatigue. Read More

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Pyoderma gangrenosum and cobalamin deficiency in systemic lupus erythematosus: a rare but non fortuitous association.

BMC Rheumatol 2021 Mar 3;5(1). Epub 2021 Mar 3.

Department of Medicine, Rheumatology Unit, Sarawak General Hospital, Kuching, Sarawak, Malaysia.

Background: Pyoderma gangrenosum (PG) is an uncommon, idiopathic, ulcerative neutrophilic dermatosis. In many cases, PG is associated with a wide variety of different disorders but SLE in association with PG is relatively uncommon. In this article we present the case of a middle aged patient with PG as the initial clinical presentation of SLE. Read More

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