1,219 results match your criteria hypoalbuminemia anemia

A comparison of characteristics and outcomes of patients with community-acquired and hospital-acquired COVID-19 in the United Kingdom: An observational study.

Respir Med 2021 03 28;178:106314. Epub 2021 Jan 28.

Royal Liverpool University Hospital, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, L7 8XP, United Kingdom.

Background And Objectives: Reports comparing the characteristics of patients and their clinical outcomes between community-acquired (CA) and hospital-acquired (HA) COVID-19 have not yet been reported in the literature. We aimed to characterise and compare clinical, biochemical and haematological features, in addition to clinical outcomes, between these patients.

Methods: This multi-centre, retrospective, observational study enrolled 488 SARS-CoV-2 positive patients - 339 with CA infection and 149 with HA infection. Read More

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Profile of Patients With Tuberculous Pleural Effusion in Qatar: A Retrospective Study.

Cureus 2020 Dec 31;12(12):e12391. Epub 2020 Dec 31.

Internal Medicine, Hamad Medical Corporation, Doha, QAT.

Introduction Tuberculosis (TB) remains one of the top 10 causes of death globally. Around 1.7 billion people are infected with mycobacterium TB worldwide, and almost 90% of cases each year are found in 30 high TB burden countries. Read More

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December 2020

High clinical heterogeneity in a Chinese pedigree of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S).

Orphanet J Rare Dis 2021 01 30;16(1):56. Epub 2021 Jan 30.

Department of Geriatric Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China.

Background: Being a newly defined disease, RVCL-S is underrecognized by clinicians globally. It is an autosomal dominantly inherited small vessel disease caused by the heterozygous C-terminal frameshift mutation in TREX1 gene. RVCL-S is featured by cerebral dysfunction, retinopathy, and vasculopathy in multiple internal organs. Read More

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January 2021

Surgical Resection for Crohn's and Cancer: A Comparison of Disease-Specific Risk Factors and Outcomes.

Dig Surg 2021 27;38(2):120-127. Epub 2021 Jan 27.

Department of Visceral Surgery, Lausanne University Hospital CHUV, University of Lausanne, Lausanne, Switzerland,

Background And Objectives: The goal of this study was to compare disease-specific risk factors and 30-day outcomes between patients with Crohn's disease (CD) and colon cancer (CC) undergoing right-sided surgical resection.

Methods: The American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP®) was interrogated to extract all patients ≥18 years undergoing elective right-sided resection for CD versus CC. Independent risk factors for surgical complications were identified through multivariable logistic regression for both groups. Read More

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January 2021

Nutritional status assessment in patients with Covid-19 after discharge from the intensive care unit.

Clin Nutr ESPEN 2021 02 13;41:423-428. Epub 2020 Oct 13.

Pneumology Department, 20 Août Hospital, CHU Ibn Rochd, Casablanca, Morocco; Faculty of Medicine and Pharmacy, University Hassan II, Casablanca, Morocco.

Introduction: The nutritional diagnosis and early nutritional management of COVID-19 patients must be integrated into the overall therapeutic strategy. The aim of our study is to assess the nutritional status of patients with COVID-19 after a stay in intensive care, to describe the prevalence of undernutrition, to determine the factors influencing undernutrition and to describe the nutritional management.

Tools And Methods: This is a descriptive observational study of adult patients admitted to the endocrinology service for additional care after a stay in intensive care during the period from April 17, 2020 to May 26, 2020. Read More

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February 2021

Development and validation of a novel score to predict dialysis inadequacy in continuous ambulatory peritoneal dialysis patients.

J Int Med Res 2021 Jan;49(1):300060520984591

Division of Nephrology, Department of Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Objective: Adequate dialysis is of great importance for continuous ambulatory peritoneal dialysis (CAPD) patients. This study aimed to develop and validate an easily applicable quantitative dialysis adequacy risk scoring system in CAPD patients based on laboratory parameters from a single blood draw.

Methods: A total of 634 CAPD patients from four study centers were enrolled in this study (345 and 289 patients in development and validation groups, respectively). Read More

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January 2021

Management of Anaemia of Chronic Disease: Beyond Iron-Only Supplementation.

Nutrients 2021 Jan 15;13(1). Epub 2021 Jan 15.

Department of Internal Medicine, University of Cagliari, 9128 Cagliari, Italy.

Chronic diseases are characterised by altered autophagy and protein metabolism disarrangement, resulting in sarcopenia, hypoalbuminemia and hypo-haemoglobinaemia. Hypo-haemoglobinaemia is linked to a worse prognosis independent of the target organ affected by the disease. Currently, the cornerstone of the therapy of anaemia is iron supplementation, with or without erythropoietin for the stimulation of haematopoiesis. Read More

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January 2021

Gallbladder and Liver Lobe Torsion in a Young Cat Presented with Hemoabdomen.

J Am Anim Hosp Assoc 2021 Jan 15. Epub 2021 Jan 15.

An 11 mo old domestic shorthair presented with acute lethargy. The cat was hypothermic and bradycardic and had pale pink mucous membranes, poor pulses, and a distended abdomen. Point-of-care ultrasound identified significant abdominal effusion, which was diagnosed to be a hemoabdomen. Read More

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January 2021

The Hardship of Recovering a Patient from Liver Failure after One Anastomosis Gastric Bypass.

Obes Surg 2021 Mar 8;31(3):1395-1398. Epub 2021 Jan 8.

Gastrintestinal, Bariatric, and Metabolic Center (GBMC), Jordan Hospital, Queen Noor St., 4th Circle, P.O BOX 3073, Amman, 11181, Jordan.

Background: The one anastomosis gastric bypass (OAGB) was first described in 2001 as a safe and effective procedure that meets the criteria for the "ideal" weight loss operation. However, revisions for malnutrition and liver failure were reported.

Case Report: We report a patient who was transferred to our institution with protein calorie malnutrition and liver failure after undergoing OAGB. Read More

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A severe case of thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly syndrome with myocardial and skeletal muscle calcification despite hypocalcemia: a case report.

J Med Case Rep 2021 Jan 6;15(1). Epub 2021 Jan 6.

Department of General Internal Medicine, Musashino Red Cross Hospital, 1-26-1, Kyonancho, Musashino-shi, Tokyo, 1808610, Japan.

Background: TAFRO (thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly) syndrome is a recently recognized disease with a variety of presentations of variable severity. In acute settings, this disease also involves organ dysfunction because of the associated systemic inflammation. However, cases of TAFRO syndrome with myocardial and/or skeletal muscle calcification have never been reported. Read More

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January 2021

[Clinical and genetic characteristics of patients with chronic enteropathy associated with SLCO2A1 gene].

Zhonghua Nei Ke Za Zhi 2021 Jan;60(1):45-50

Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To determine the clinical features and genetic characters of patients with chronic enteropathy associated SLCO2A1 gene (CEAS). Five CEAS patients diagnosed at Peking Union Medical College Hospital from January 2012 to December 2019 were enrolled in this study. The clinical manifestations, laboratory test, radiological and endoscopic findings, gene detections, treatments and prognosis of these patients were reviewed and analyzed. Read More

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January 2021

Di(2-ethylhexyl) adipate plasticizer triggers hepatic, brain, and cardiac injury in rats: Mitigating effect of Peganum harmala oil.

Ecotoxicol Environ Saf 2021 Jan 13;208:111620. Epub 2020 Nov 13.

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt. Electronic address:

Di(2-ethylhexyl) adipate (DEHA) is a widely used plasticizer and prevalent environmental contaminant. In this study, DEHA concentrations in the milk, cheese, and butter samples wrapped with food-grade commercial polyethylene films and stored at 4 °C for 30 days were detected using gas chromatographic analysis. Also, the effects of exposure to a high dose of DEHA for a long duration on the liver, brain, and heart of Wistar rats were assessed. Read More

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January 2021

A case report of diffuse hyperplastic gastropathy with multiple polypoid formations in a patient with pernicious anemia, Helicobacter pylori infection, hypergastrinemia and hypoalbuminaemia: Do not forget of Ménétrier's disease.

Int J Surg Case Rep 2020 12;77:498-502. Epub 2020 Nov 12.

Department of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.

Introduction: Ménétrier's disease is a rare condition, frequently associated with Helicobacter pylori infection, hypergastrinemia and hypoalbuminaemia.

Presentation Of The Case: A case of a 55 years-old female patient with a previous diagnosis of pernicious anemia complaining of epigastric discomfort, hyporexia, vomiting, and weight loss is reported. Endoscopy showed multiple gastric polyploid formations and Helicobacter pylori infection was detected. Read More

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November 2020

Clinical epidemiology and outcome of HIV-associated talaromycosis in Guangdong, China, during 2011-2017.

HIV Med 2020 12;21(11):729-738

Infectious Disease Center, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.

Objectives: Talaromycosis is an invasive mycosis endemic to Southeast Asia. This study aimed to investigate the epidemiology, clinical features and prognostic factors of HIV-associated talaromycosis in Guangdong, China.

Methods: We retrospectively evaluated HIV patients hospitalized with histopathology- or culture-confirmed talaromycosis between 2011 and 2017. Read More

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December 2020

Fatal murine typhus with hemophagocytic lymphohistiocytosis in a child.

Rev Inst Med Trop Sao Paulo 2020 18;62:e99. Epub 2020 Dec 18.

Universidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Laboratorio de Enfermedades Emergentes y Reemergentes, Mérida, Yucatán, México.

Hemophagocytic lymphohistiocytosis is a rare complication in Rickettsia typhi infections. We report the case of a 2-year-old boy with sudden night-onset fever, pallor, neck adenopathy and erythematous macular rash on the thorax, thighs and buttocks. During admission, he developed hyponatremia, hypoalbuminemia, anemia, thrombocytopenia, leukopenia, neutropenia, liver damage, hemorrhages and persistent fever. Read More

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January 2021

Chronic Enteropathy Associated with SLCO2A1 with Pachydermoperiostosis.

Intern Med 2020 15;59(24):3147-3154. Epub 2020 Dec 15.

Department of General Internal Medicine, Saitama Medical University, Japan.

A 49-year-old man complained of chronic palpitation and shortness of breath, which had recently become exacerbated. A blood examination indicated severe refractory anemia and hypoproteinemia. Physical examinations revealed anemia, a systolic murmur, and spoon nails. Read More

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Clinical features and outcome of maintenance hemodialysis patients with COVID-19 from a tertiary nephrology care center in Romania.

Ren Fail 2021 Dec;43(1):49-57

"Dr. Carol Davila" Teaching Hospital of Nephrology, Bucharest, Romania.

Background: There is limited information about the clinical characteristics, treatment and outcome of maintenance hemodialysis patients with COVID-19. Moreover, regional differences are also conceivable since the extend and severity of outbreaks varied among countries.

Methods: In this retrospective, observational, single-center study, we analyzed the clinical course and outcomes of 37 maintenance hemodialysis patients (median age 64 years, 51% men) hospitalized with COVID-19 from 24 March to 22 May 2020 as confirmed by real-time PCR. Read More

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December 2021

Base Deficit, Serum Albumin Level And Blood Haemoglobin Concentration Can Be Used As Predictor Factors For Mortality In Major Burn Patients.

Ann Burns Fire Disasters 2020 Sep;33(3):209-215

Chest and Plastic Surgery Department, Faculty of Medicine, Menoufia University, Egypt.

Hypoalbuminemia as seen in major burn injury results in widespread endothelial dysfunction. Base deficit provides the best estimate for degree of tissue anoxia. Acute blood loss describes anemia present in burn patients. Read More

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September 2020

Valvular endocarditis in the horse: 20 cases (1993-2020).

Can Vet J 2020 12;61(12):1290-1294

Rivendell Equine Veterinary Services, 72 Leeson Street South, Grand Valley, Ontario L9W 5S5 (Henderson); Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Diaz, Martins, Kenney, Baird, Arroyo).

Medical records of 20 horses with a confirmed diagnosis of valvular endocarditis at the Ontario Veterinary College between January 1, 1993 and February 3, 2020 were reviewed. The diagnosis was based on physical examination findings, complete blood (cell) count (CBC), serum biochemistry, echocardiography, blood culture, and post-mortem findings. Common presenting signs included tachycardia, pyrexia, weight loss, lameness/joint distension, and a heart murmur. Read More

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December 2020

[Interleukin-6-producing paraganglioma mimicking multicentric Castleman disease].

Rinsho Ketsueki 2020 ;61(11):1605-1610

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine.

Multicentric Castleman disease (MCD) comprises a heterogeneous group of lymphoproliferative disorders. Interleukin 6 (IL-6) plays an important role in the MCD pathophysiology. Here, we report the case of a 17-year-old Japanese man who presented with fever, headache, fatigue, and weight loss, with normal blood pressure. Read More

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February 2021

Toxicity of L19-Interleukin 2 Combined with Stereotactic Body Radiation Therapy: A Phase 1 Study.

Int J Radiat Oncol Biol Phys 2021 Apr 4;109(5):1421-1430. Epub 2020 Dec 4.

The D-Lab & The M-Lab, Department of Precision Medicine, GROW-School for Oncology, Maastricht University, Maastricht, The Netherlands. Electronic address:

Purpose: The immunocytokine L19-IL2 delivers interleukin-2 to the tumor by exploiting the selective L19-dependent binding of extradomain B of fibronectin on tumor blood vessels. In preclinical models, L19-IL2 has been shown to enhance the local and abscopal effects of radiation therapy. The clinical safety of L19-IL2 monotherapy has been established previously. Read More

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Impact of Surgery on Older Patients Hospitalized With an Acute Abdomen: Findings From the Older Persons Surgical Outcome Collaborative.

Front Surg 2020 16;7:583653. Epub 2020 Nov 16.

Department of Geriatric Medicine, Cardiff University, Cardiff, United Kingdom.

The impact of surgery compared to non-surgical management of older general surgical patients is not well researched. We examined the association between management and adverse outcomes in a cohort of emergency general surgery patients aged > 65 years. This multi-center study included 727 patients (mean+/-SD, 77. Read More

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November 2020

Five-Year Mortality Analysis in Hemodialysis Patients in a Single-Center in Dubai.

Saudi J Kidney Dis Transpl 2020 Sep-Oct;31(5):1062-1068

Department of Nephrology, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.

The purpose of this study is to determine the mortality among patients on hemodialysis (HD). This observational cohort study was conducted at Dubai Hospital during the period between January 2012 and December 2016. All adults' patients with end-stage renal disease (ESRD) on HD irrespective of their age, gender, and duration of dialysis were enrolled. Read More

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November 2020

Prevalence, associated factors and cardiocerebral vascular prognosis of anaemia among patients on chronic haemodialysis in South Guangdong, China.

J Int Med Res 2020 Nov;48(11):300060520965791

Department of Nephrology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province, China.

Objective: To assess the prevalence, associated factors and cardiocerebral vascular prognosis of anaemia in patients undergoing haemodialysis.

Methods: This multicentre, retrospective, observational cohort study included patients on maintenance haemodialysis in South Guangdong, China. Anaemia in haemodialysis was defined as haemoglobin (Hb) <90 g/l. Read More

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November 2020

A Multicenter Study of Docetaxel at a Dose of 100 mg/m in Japanese Patients with Advanced or Recurrent Breast Cancer.

Intern Med 2021 Apr 16;60(8):1183-1190. Epub 2020 Nov 16.

Departments of Breast and Endocrine Surgery, Okayama University Hospital, Japan.

Objective This study examined the pharmacokinetics, safety and anti-tumor activity of docetaxel at a dose of 100 mg/m in Japanese patients with advanced or recurrent breast cancer. Methods Japanese patients with advanced or recurrent breast cancer received docetaxel at a dose of 100 mg/m intravenously every three weeks. The pharmacokinetics were assessed during the first cycle. Read More

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[Wilkie's syndrome caused by exogenous hyperthyroidism in a patient with primary autoimmune hypothyroidism: a case report and literature review].

Rev Gastroenterol Peru 2020 Jul-Sep;40(3):274-277

Departamento de Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Ciudad de México, México.

Wilkie's syndrome or superior mesenteric artery syndrome is an unusual cause of proximal intestinal obstruction, primarily attributed to recent weight loss. We report the case of a 19-year-old woman comes to our clinic and reports weight loss, abdominal pain, nausea, and vomiting. Laboratory tests revealed anemia, hypoalbuminemia, hypomagnesemia, and a suppressed thyroid stimulating hormone secondary to levothyroxine. Read More

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November 2020

The necessity of routine postoperative laboratory tests after total hip arthroplasty for hip fracture in a semi-urgent clinical setting.

J Orthop Traumatol 2020 Nov 10;21(1):19. Epub 2020 Nov 10.

Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuanjiagang, Yuzhong District, Chongqing, 400016, China.

Background: Recent studies suggest that routine postoperative laboratory tests are not necessary after primary elective total hip arthroplasty (THA). This study aims to evaluate the utility of routine postoperative laboratory tests in patients undergoing THA for hip fracture in a semi-urgent clinical setting.

Materials And Methods: This retrospective study included 213 consecutive patients who underwent primary unilateral THA for hip fractures. Read More

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November 2020

Clinical characteristics of 10 children with a pediatric inflammatory multisystem syndrome associated with COVID-19 in Iran.

BMC Pediatr 2020 11 9;20(1):513. Epub 2020 Nov 9.

Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Although symptoms and signs of COVID-19 (Coronavirus disease 2019) in children are milder than adults, there are reports of more severe cases which were defined as pediatric inflammatory multisystem syndrome (PIMS). The purpose of this report was to describe the possible association between COVID-19 and PIMS in children.

Methods: From 28 March to 24 June 2020, 10 febrile children were admitted with COVID-19 infection showing characteristics of PIMS in Buali tertiary hospital of Sari, in Mazandaran province, northern Iran. Read More

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November 2020

Lysinuric protein intolerance: Pearls to detect this otherwise easily missed diagnosis.

Transl Sci Rare Dis 2020 Aug 3;5(1-2):81-86. Epub 2020 Aug 3.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

Background: Lysinuric protein intolerance (LPI) is a rare autosomal recessive disorder characterized by deficient membrane transport of cationic amino acids. It is caused by pathogenic variants in SLC7A7, resulting in impairment of intestinal import and renal proximal tubule loss of the affected amino acids. LPI typically presents with gastrointestinal symptoms, such as vomiting, diarrhea, and failure to thrive. Read More

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Influence of intradialytic systolic blood pressure changes on arteriovenous access thrombosis in maintenance hemodialysis patients.

Int J Clin Pract 2021 Mar 20;75(3):e13799. Epub 2020 Nov 20.

Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Background: Arteriovenous access (AV) thrombosis is an important and preventable problem amongst chronic hemodialysis (HD) patients. Systolic blood pressure (SBP) fluctuation relates to higher cardiovascular mortality amongst these patients. We proposed there is a close relation between SBP changes and arteriovenous (AV) access thrombosis. Read More

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