45 results match your criteria hypholoma fasciculare

White-rot fungi-mediated biodegradation of cytostatic drugs - bleomycin and vincristine.

J Hazard Mater 2021 Apr 5;407:124632. Epub 2020 Dec 5.

Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Łódź, Poland. Electronic address:

The contamination of the environment with anticancer drugs, which show recalcitrance to conventional wastewater treatment, has become a significant ecological threat. Fungi represent a promising non-conventional biological alternative for water conditioning. The aim of this work was to evaluate the efficacy of five white-rot fungi (Fomes fomentarius (CB13), Hypholoma fasciculare (CB15), Phyllotopsis nidulans (CB14), Pleurotus ostreatus (BWPH) and Trametes versicolor (CB8)) in the removal of bleomycin and vincristine. Read More

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Molecular prospecting for cryptic species of the Hypholoma fasciculare complex: toward the effective and practical delimitation of cryptic macrofungal species.

Sci Rep 2020 08 6;10(1):13224. Epub 2020 Aug 6.

Makino Herbarium, Tokyo Metropolitan University, Hachioji, Tokyo, 192-0397, Japan.

Many macrofungal cryptic species remain unidentified. A possible solution is to increase the number of loci analyzed and use rigorous statistics for macrofungal species delimitation. To validate this assumption, cryptic species of the Hypholoma fasciculare complex, a group of common wood-decomposing fungi, were attempted to be delineated. Read More

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Antiproliferative, Immunostimulatory, and Anti-Inflammatory Activities of Extracts Derived from Mushrooms Collected in Haida Gwaii, British Columbia (Canada).

Int J Med Mushrooms 2019 ;21(7):629-643

Chemistry Program, University of Northern British Columbia, Prince George, British Columbia, Canada.

Wild mushrooms, while largely explored for their ecological significance, have not been systematically studied for their medicinal properties. This is the first report of biological activities of mushrooms from Haida Gwaii, British Columbia, Canada. The 17 mushroom species in this study were collected from multiple locations on Haida Gwaii and were screened for antiproliferative, immunostimulatory, and anti-inflammatory activities. Read More

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February 2020

Antimicrobial properties of basidiomycota macrofungi to isolated from patients with cystic fibrosis.

Int J Mycobacteriol 2019 Jan-Mar;8(1):93-97

Northern Ireland Public Health Laboratory, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland, BT9 7AD; School of Medicine, Dentistry and Biomedical Science, Centre for Experimental Medicine, Queen's University, 97 Lisburn Road, Belfast; School of Biomedical Sciences, Ulster University, Cromore Road, Coleraine, Co. Londonderry, Northern Ireland, BT52 1SA, UK.

Background: Antimicrobial resistance (AMR) has now emerged as a global public health crisis. Of particular concern is AMR associated with the genus Mycobacterium, including Mycobacterium tuberculosis and the nontuberculous mycobacteria (NTM). Emergence of the NTM, in particular Mycobacterium abscessus, in patients with cystic fibrosis (CF) represents both a diagnostic and a treatment dilemma. Read More

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Elemental distribution including toxic elements in edible and inedible wild growing mushrooms from South Africa.

Environ Sci Pollut Res Int 2019 Mar 25;26(8):7913-7925. Epub 2019 Jan 25.

School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.

Macro-elements (Ca, Fe, K, Mg and Na) and trace elements including some toxic (As, Be, Cd, Co, Cu, Mn, Ni, Pb, Se and Zn) were determined in edible and inedible wild-growing mushrooms (Amanita rubescens, Auricularia polytricha, Boletus edulis, Boletus mirabilis, Clavulina cristata, Helvella crispa, Lactarius deliciosus, Suillus luteus, Termitomyces microcarpus, Termitomyces reticulatus, Termitomyces clypeatus, Termitomyces umkowaanii, Amanita foetidissima, Amanita muscaria, Amanita pantherina, Aseroe rubra, Chlorophyllum molybdites, Ganoderma lucidum, Gymnopilus junonius, Hypholoma fasciculare, Lentinus villosus, Lepista caffrorum, Pycnoporus sanguineus, Panaeolus papilionaceus, Pisolithus tinctorius, Pleurotus ostreatus, Podaxis pistillaris, Russula sardonia, Scleroderma citrinum, Scleroderma michiganense). Analyses of samples were carried out using inductively coupled plasma-optical emission spectrometry. The elemental content in both edible and inedible mushrooms, in decreasing order, was found to be K > Na > Ca > Mg > Fe > Mn > Zn > Cu > Se > Co > Ni > Be > Pb ≥ Cd > As. Read More

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Suitability of dried herbarium specimens for NMR metabolomics of mushrooms. A comparison of four species of the genera Kuehneromyces and Hypholoma (Strophariaceae).

Fungal Biol 2018 Feb - Mar;122(2-3):138-146. Epub 2017 Dec 8.

The Instrument Centre, Department of Chemistry, University of Turku, FI-20014 Turku, Finland.

Herbarium specimens are a treasure trove for biochemical studies. However, this implies understanding of the chemical changes during the drying and storage of the specimen. We compared herbarium specimens at different ages and fresh samples of four mushroom species (Kuehneromyces mutabilis, Hypholoma capnoides, Kuehneromyces lignicola, Hypholoma fasciculare) of two genera in the family Strophariaceae by using proton nuclear magnetic resonance (H NMR) spectroscopy combined with principal component analysis (PCA). Read More

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January 2019

Improved vectors for Agrobacterium mediated genetic manipulation of Hypholoma spp. and other homobasidiomycetes.

J Microbiol Methods 2017 11 24;142:4-9. Epub 2017 Aug 24.

Molecular Plant Pathology and Fungal Biology Group, University of Bristol, School of Biological Sciences, 24 Tyndall Avenue Bristol, BS8 1TQ, UK. Electronic address:

The basidiomycete fungi Hypholoma fasciculare and H. sublateritium are both prolific producers of sesquiterpenes and triterpenes, some of which have relevant pharmaceutical properties. Although H. Read More

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November 2017

PCR-Based Method for the Detection of Toxic Mushrooms Causing Food-Poisoning Incidents.

Shokuhin Eiseigaku Zasshi 2017 ;58(3):132-142

Osaka Prefectural Institute of Public Health.

In this study, species-specific identification of five toxic mushrooms, Chlorophyllum molybdites, Gymnopilus junonius, Hypholoma fasciculare, Pleurocybella porrigens, and Tricholoma ustale, which have been involved in food-poisoning incidents in Japan, was investigated. Specific primer pairs targeting internal transcribed spacer (ITS) regions were designed for PCR detection. The specific amplicons were obtained from fresh, cooked, and simulated gastric fluid (SGF)-treated samples. Read More

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September 2017

Monitoring metabolites from Schizophyllum commune interacting with Hypholoma fasciculare combining LESA-HR mass spectrometry and Raman microscopy.

Anal Bioanal Chem 2015 Mar 27;407(8):2273-82. Epub 2014 Dec 27.

Department of Microbial Communication, Institute of Microbiology, Friedrich Schiller University, Neugasse 25, 07743, Jena, Germany.

Microbial competition for territory and resources is inevitable in habitats with overlap between niches of different species or strains. In fungi, competition is brought about by antagonistic mycelial interactions which alter mycelial morphology, metabolic processes, secondary metabolite release, and extracellular enzyme patterns. Until now, we were not able study in vivo chemical interactions of different colonies growing on the same plate. Read More

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Xanthine oxidase inhibitory activity of Hungarian wild-growing mushrooms.

Phytother Res 2014 Aug 16;28(8):1204-10. Epub 2014 Jan 16.

Department of Pharmacognosy, University of Szeged, Eötvös utca 6, H-6720, Szeged, Hungary.

Mushrooms represent a remarkable and yet largely unexplored source of new, biologically active natural products. In this work, we report on the xanthine oxidase (XO) inhibitory activity of 47 wild-growing mushrooms native to Hungary. Aqueous and organic (n-hexane, chloroform, and 50% methanol) extracts of selected mushrooms from different families were screened for their XO inhibitory activities. Read More

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Screening of ecologically diverse fungi for their potential to pretreat lignocellulosic bioenergy feedstock.

Appl Microbiol Biotechnol 2014 Apr 7;98(7):3355-70. Epub 2014 Feb 7.

Department of Bioenergy, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, 04318, Leipzig, Germany.

A widespread and hitherto by far underexploited potential among ecologically diverse fungi to pretreat wheat straw and digestate from maize silage in the future perspective of using such lignocellulosic feedstock for fermentative bioenergy production was inferred from a screening of nine freshwater ascomycetes, 76 isolates from constructed wetlands, nine peatland isolates and ten basidiomycetes. Wheat straw pretreatment was most efficient with three ascomycetes belonging to the genera Acephala (peatland isolate) and Stachybotrys (constructed wetland isolates) and two white-rot fungi (Hypholoma fasciculare and Stropharia rugosoannulata) as it increased the amounts of water-extractable total sugars by more than 50 % and sometimes up to 150 % above the untreated control. The ascomycetes delignified wheat straw at rates (lignin losses between about 31 and 40 % of the initial content) coming close to those observed with white-rot fungi (about 40 to 57 % lignin removal). Read More

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Contrasting effects of elevated temperature and invertebrate grazing regulate multispecies interactions between decomposer fungi.

PLoS One 2013 23;8(10):e77610. Epub 2013 Oct 23.

Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom.

Predicting the influence of biotic and abiotic factors on species interactions and ecosystem processes is among the primary aims of community ecologists. The composition of saprotrophic fungal communities is a consequence of competitive mycelial interactions, and a major determinant of woodland decomposition and nutrient cycling rates. Elevation of atmospheric temperature is predicted to drive changes in fungal community development. Read More

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February 2015

Clues for regulatory processes in fungal uptake and transfer of minerals to the basidiospore.

Biol Trace Elem Res 2013 Jul 12;154(1):140-9. Epub 2013 Jun 12.

Institute of Geosciences, Friedrich-Schiller-University, Burgweg 11, 07749 Jena, Germany.

Several fungal species are notorious for the preferential acquisition of toxicants such as AsCdHgPbU in their wild-grown basidiomes, but it is not known how, or whether at all, mineral uptake is regulated. In this study, basidiomes of Kuehneromyces mutabilis, Pleurotus ostreatus, and Hypholoma fasciculare were grown on Fagus sylvatica logs embedded in sand, uranium-overburden soil, and garden soil (SIO) at a lab scale to raise the accessible mineral resources 30 to >1,000 times over those available in the timber alone. Non-embedded logs and a field culture established on SIO served as controls. Read More

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Extracellular enzymes of the white-rot fungus Fomes fomentarius and purification of 1,4-β-glucosidase.

Appl Biochem Biotechnol 2013 Jan 14;169(1):100-9. Epub 2012 Nov 14.

Laboratory of Environmental Microbiology, Institute of Microbiology of the ASCR, v.v.i., Vídeňská 1083, 14220 Praha 4, Czech Republic.

Production of the lignocellulose-degrading enzymes endo-1,4-β-glucanase, 1,4-β-glucosidase, cellobiohydrolase, endo-1,4-β-xylanase, 1,4-β-xylosidase, Mn peroxidase, and laccase was characterized in a common wood-rotting fungus Fomes fomentarius, a species able to efficiently decompose dead wood, and compared to the production in eight other fungal species. The main aim of this study was to characterize the 1,4-β-glucosidase produced by F. fomentarius that was produced in high quantities in liquid stationary culture (25. Read More

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January 2013

A new effective assay to detect antimicrobial activity of filamentous fungi.

Microbiol Res 2013 Jan 5;168(1):1-5. Epub 2012 Oct 5.

CIMO/School of Agriculture, Polytechnic Institute of Bragança, Campus de Santa Apolónia, Apartado 1172, 5301-854 Bragança, Portugal.

The search for new antimicrobial compounds and the optimization of production methods turn the use of antimicrobial susceptibility tests a routine. The most frequently used methods are based on agar diffusion assays or on dilution in agar or broth. For filamentous fungi, the most common antimicrobial activity detection methods comprise the co-culture of two filamentous fungal strains or the use of fungal extracts to test against single-cell microorganisms. Read More

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January 2013

Outcomes of fungal interactions are determined by soil invertebrate grazers.

Ecol Lett 2011 Nov 19;14(11):1134-42. Epub 2011 Sep 19.

Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK.

Saprotrophic fungal community composition, determined by the outcome of competitive mycelial interactions, is one of the many key factors affecting soil nutrient mineralisation and decomposition rates. Fungal communities are not generally predicted to be regulated by top-down factors, such as predation, but rather by bottom-up factors, including resource availability. We show that invertebrate grazers can exert selective pressures on fungal decomposer communities in soil, reversing the outcomes of competitive interactions. Read More

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November 2011

Simulated nitrogen deposition affects wood decomposition by cord-forming fungi.

Oecologia 2011 Dec 7;167(4):1177-84. Epub 2011 Jul 7.

Earthwatch Institute, Oxford, UK.

Anthropogenic nitrogen (N) deposition affects many natural processes, including forest litter decomposition. Saprotrophic fungi are the only organisms capable of completely decomposing lignocellulosic (woody) litter in temperate ecosystems, and therefore the responses of fungi to N deposition are critical in understanding the effects of global change on the forest carbon cycle. Plant litter decomposition under elevated N has been intensively studied, with varying results. Read More

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December 2011

Saprotrophic basidiomycete mycelia and their interspecific interactions affect the spatial distribution of extracellular enzymes in soil.

FEMS Microbiol Ecol 2011 Oct 26;78(1):80-90. Epub 2011 May 26.

Laboratory of Environmental Microbiology, Institute of Microbiology of the ASCR, Prague, Czech Republic.

Saprotrophic cord-forming basidiomycetes are important decomposers of lignocellulosic substrates in soil. The production of extracellular hydrolytic enzymes was studied during the growth of two saprotrophic basidiomycetes, Hypholoma fasciculare and Phanerochaete velutina, across the surface of nonsterile soil microcosms, along with the effects of these basidiomycetes on fungi and bacteria within the soil. Higher activities of α-glucosidase, β-glucosidase, cellobiohydrolase, β-xylosidase, phosphomonoesterase and phosphodiesterase, but not of arylsulphatase, were recorded beneath the mycelia. Read More

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October 2011

Effect of competitive interactions between ectomycorrhizal and saprotrophic fungi on Castanea sativa performance.

Mycorrhiza 2012 Jan 12;22(1):41-9. Epub 2011 Apr 12.

CIMO/School of Agriculture, Polytechnic Institute of Bragança, Bragança, Portugal.

In Northeast of Portugal, the macrofungal community associated to chestnut tree (Castanea sativa Mill.) is rich and diversified. Among fungal species, the ectomycorrhizal Pisolithus tinctorius and the saprotroph Hypholoma fasciculare are common in this habitat. Read More

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January 2012

Ethanolic and aqueous extracts derived from Australian fungi inhibit cancer cell growth in vitro.

Mycologia 2011 May-Jun;103(3):458-65. Epub 2011 Jan 24.

School of Pharmacy, Griffith University, Gold Coast campus, Queensland 4222, Australia.

Fifteen Australian macrofungi were investigated for cytotoxic activity. Ethanol, cold and hot water extracts of each species were screened for cytotoxic activity against normal mouse fibroblast cells (NIH/3T3), healthy human epithelial kidney cells (HEK-293), four cancer cell lines, gastric adenocarcinoma cells (AGS), two mammary gland adenocarcinoma cells (MDA-MB-231, MCF7) and colorectal adenocarcinoma cells (HT-29) with a validated MTT assay. Most extracts derived from Omphalotus nidiformis, Cordyceps cranstounii and Cordyceps gunnii demonstrated significant cytotoxic activity toward a variety of cancer cell lines. Read More

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September 2011

Microarray analysis of differential gene expression elicited in Trametes versicolor during interspecific mycelial interactions.

Fungal Biol 2010 Aug 31;114(8):646-60. Epub 2010 May 31.

School of Biosciences, Cardiff University, Main Building, Park Place, Cardiff CF10 3TL, UK.

Trametes versicolor is an important white rot fungus of both industrial and ecological interest. Saprotrophic basidiomycetes are the major decomposition agents in woodland ecosystems, and rarely form monospecific populations, therefore interspecific mycelial interactions continually occur. Interactions have different outcomes including replacement of one species by the other or deadlock. Read More

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Mutual influence of soil basidiomycetes and white mustard plants on their enzymatic and catabolic activities.

J Basic Microbiol 2011 Feb 30;51(1):40-51. Epub 2010 Aug 30.

Institute of Earth Sciences, Friedrich-Schiller-University, Burgweg 11, D-07749 Jena, Germany.

Liquid and volatile emanations in interactions of soil basidiomycetes with herbs affect fungal oxidoreductases and stress-related plant peroxidases (PO). In this study, gnotobiotic co-cultures between 6 non-pathogenic saprobes and 2 ectomycorrhizal basidiomycetes with the non-host plant white mustard were established on glucose-salt medium with the respective controls. Determined were oxidoreductase activities for culture fluids and plant tissues at initial fungal idiophase and degradation rates of Remazol-BBR and 5 PAHs. Read More

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February 2011

Mechanism of antibacterial activity of the white-rot fungus Hypholoma fasciculare colonizing wood.

Can J Microbiol 2010 May;56(5):380-8

Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Boterhoeksestraat 48, Heteren 6666 GA, Netherlands.

In a previous study it was shown that the number of wood-inhabiting bacteria was drastically reduced after colonization of beech (Fagus sylvatica) wood blocks by the white-rot fungus Hypholoma fasciculare, or sulfur tuft (Folman et al. 2008). Here we report on the mechanisms of this fungal-induced antibacterial activity. Read More

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Methylovirgula ligni gen. nov., sp. nov., an obligately acidophilic, facultatively methylotrophic bacterium with a highly divergent mxaF gene.

Int J Syst Evol Microbiol 2009 Oct 21;59(Pt 10):2538-45. Epub 2009 Jul 21.

S. N. Winogradsky Institute of Microbiology, Russian Academy of Sciences, Moscow 117312, Russia.

Two strains of Gram-negative, aerobic, non-pigmented, non-motile, rod-shaped bacteria were isolated from beechwood blocks during decay by the white-rot fungus Hypholoma fasciculare and were designated strains BW863(T) and BW872. They are capable of methylotrophic growth and assimilate carbon via the ribulose-bisphosphate pathway. In addition to methanol, the novel isolates utilized ethanol, pyruvate and malate. Read More

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October 2009

Phylogenetic composition and properties of bacteria coexisting with the fungus Hypholoma fasciculare in decaying wood.

ISME J 2009 Oct 11;3(10):1218-21. Epub 2009 Jun 11.

Laboratory of Environmental Microbiology, Institute of Microbiology of the ASCR, v.v.i., Prague 4 14220, Czech Republic.

White-rot fungi are major degraders of woody materials in terrestrial environments because of their ability to decompose lignin. However, little is known on the possible associations of white-rot fungi with other microorganisms during wood decay. We investigated the numbers, community composition and functional traits of bacteria present in natural wood samples under advanced decay by the white-rot basidiomycete Hypholoma fasciculare. Read More

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October 2009

Substrate role in the accumulation of heavy metals in sporocarps of wild fungi.

Biometals 2009 Oct 31;22(5):835-41. Epub 2009 Mar 31.

Departamento de Producción Vegetal y Tecnología Agrícola, Universidad de Castilla-La Mancha, RD de Calatrava 7, Ciudad Real, Spain.

The distribution of neodymium, lead, thorium and uranium was investigated in about 100 samples of 12 different species of common, edible and non-edible mushrooms collected in unpolluted areas in the province of Ciudad Real, Central Spain. The quantitative analysis of heavy metals was performed by X-ray fluorescence spectrometry (a simple, accurate and non-destructive method). The concentration of these elements was related to three factors: mushroom specie, life style/substrate and study area. Read More

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October 2009

Chemical composition and biological properties of portuguese wild mushrooms: a comprehensive study.

J Agric Food Chem 2008 May 25;56(10):3856-62. Epub 2008 Apr 25.

CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Apartado 1172, 5301-855 Bragança, Portugal.

The chemical composition and biological properties of Portuguese wild mushrooms ( Cantharellus cibarius, Hypholoma fasciculare, Lepista nuda, Lycoperdon molle, Lycoperdon perlatum, Ramaria botrytis, Tricholoma acerbum) were evaluated in order to assess these products as sources of nutrients and nutraceuticals. The analyzed mushrooms contain very useful phytochemicals such as phenolics, tocopherols, ascorbic acid, and carotenoids. All of the species proved to have antioxidant activity (measured by four different methods), being more significant for R. Read More

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Evaluation of trace metal contents of some wild edible mushrooms from Black sea region, Turkey.

J Hazard Mater 2008 Dec 13;160(2-3):462-7. Epub 2008 Mar 13.

Karadeniz Technical University, Fatih Faculty of Education, Department of Biology, 61335 Söğutlu, Trabzon, Turkey.

Fructification organs of Calvatia excipuliformis, Lycoperdon perlatum, Laccaria amethystea, Armillaria mellea, Marasmius oreades, Xerula radicata, Cantharellus cibarius, Craterellus cornucopioides, Cantharellus tubaeformis, Hypholoma fasciculare, Clitocybe gibba, Collybia dryophila, Lepista nuda and Mycena aetites were collected from different localities in Black sea region of Turkey. Their trace metals concentrations were determined by atomic absorption spectrometry after wet and microwave digestion. The results were (as mg/kg) 150-1741 for iron, 15. Read More

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December 2008

Impact of white-rot fungi on numbers and community composition of bacteria colonizing beech wood from forest soil.

FEMS Microbiol Ecol 2008 Feb;63(2):181-91

Department of Plant Microorganism Interactions, NIOO-Centre for Terrestrial Ecology, ZG Heteren, The Netherlands.

White-rot fungi are important wood-decomposing organisms in forest ecosystems. Their ability to colonize and decompose woody resources may be strongly influenced by wood-inhabiting bacteria that grow on easily utilizable compounds e.g. Read More

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February 2008

Wood-decay fungi in fine living roots of conifer seedlings.

New Phytol 2007 ;174(2):441-446

Department of Forest Mycology and Pathology, Swedish University of Agricultural Sciences, PO Box 7026, SE-750 07 Uppsala, Sweden.

The mycorrhizal basidiomycetes are known to have multiple, independent evolutionary origins from saprotrophic ancestors. To date, a number of studies have revealed functional resemblance of mycorrhizal fungi to free-living saprotrophs, but information on the ability of saprotrophic fungi to perform as mycorrhizal symbionts is scarce. Here, the objective was to investigate the ability of three wood-decay fungi, Phlebiopsis gigantea, Phlebia centrifuga and Hypholoma fasciculare, to colonize fine roots of conifer seedlings. Read More

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