Neuroimage 2014 Nov 17;102 Pt 1:49-59. Epub 2013 Jun 17.
Department of Neurological, and Movement Sciences, Section of Neurology, University of Verona, Italy; Department of Neurophysiology, Foundation IRCCS San Camillo Hospital, Venice, Italy; Clinical Neurophysiology and Functional Neuroimaging Unit, AOUI of Verona, Verona, Italy.
When localization of the epileptic focus is uncertain, the epileptic activity generator may be more accurately identified with non-invasive imaging techniques which could also serve to guide stereo-electroencephalography (sEEG) electrode implantation. The aim of this study was to assess the diagnostic value of perfusion magnetic resonance imaging with arterial spin labeling (ASL) in the identification of the epileptogenic zone, as compared to the more invasive positron-emission tomography (PET) and other established investigation methods for source imaging of electroencephalography (EEG) data. In 6 patients with drug-resistant focal epilepsy, standard video-EEG was performed to identify clinical seizure semeiology, and high-density EEG, ASL and FDG-PET to non-invasively localize the epileptic focus. Read More