Circ Cardiovasc Interv 2020 06 10;13(6):e009019. Epub 2020 Jun 10.
School of Cardiovascular Medicine and Sciences, British Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre (H.R., O.M.D., M.R., H.M., H.E., A.W., D.P.), King's College London, United Kingdom.
Background: Among patients with angina and nonobstructive coronary artery disease, those with coronary microvascular dysfunction have a poor outcome. Coronary microvascular dysfunction is usually diagnosed by assessing flow reserve with an endothelium-independent vasodilator like adenosine, but the optimal diagnostic threshold is unclear. Furthermore, the incremental value of testing endothelial function has never been assessed before. Read More