46,761 results match your criteria hybrid system

Hybrid capacitive deionization of NaCl and toxic heavy metal ions using Faradic electrodes of silver nanospheres decorated pomegranate peel-derived activated carbon.

Environ Res 2021 Apr 14:111110. Epub 2021 Apr 14.

Department of Chemical Engineering, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates. Electronic address:

Capacitive deionization (CDI) is an evolving technology for eradicating salt and toxic heavy metal ions from brackish wastewater. However, traditional CDI electrodes have lower salt adsorption capacity and inadequate adsorption of selective metal ions for long-term operations. Herein, Ag nanospheres incorporated pomegranate peel-derived activated carbon (Ag/P-AC) was prepared and implied to the CDI process for removing NaCl, toxic mono-, di-, and trivalent metal ions. Read More

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Polymeric lipid hybrid nanoparticles as a delivery system enhance the antitumor effect of Emodin in vitro and in vivo.

J Pharm Sci 2021 Apr 14. Epub 2021 Apr 14.

College of Pharmacy, Jinan University, Guangzhou, 510632, China; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou, 510632, China; Cancer Research Institute of Jinan University, Guangzhou, 510632, China; Interventional Cancer Institute of Chinese Integrative Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China. Electronic address:

This study aimed to evaluate the therapeutic efficacy of Emodin-loaded polymer lipid hybrid nanoparticles (E-PLNs) for breast cancer. The size, Zeta potential, surface morphology, encapsulation efficiency, stability, in vitro drug release of E-PLNs prepared by the nanoprecipitation method were characterized. The uptake, in-vitro cytotoxicities and apoptosis of free drug, E-PLNs were investigated against MCF-7 cells. Read More

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Advanced hybrid closed-loop system: first successful clinical case after total pancreatectomy.

Acta Diabetol 2021 Apr 16. Epub 2021 Apr 16.

Diabetes Care Unit, Catholic University, Universitario Agostino Gemelli, L.Go Agostino Gemelli, 800168, PoliclinicoRome, Italy.

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Bioinspired Hydrophilic-Hydrophobic Janus Composites for Highly Efficient Solar Steam Generation.

ACS Appl Mater Interfaces 2021 Apr 16. Epub 2021 Apr 16.

Key Laboratory of Bionic Engineering (Ministry of Education), College of Biological and Agricultural Engineering, Jilin University, Changchun, Jilin 130022, China.

Solar energy has received extensive attention as a renewable and sufficient energy source. Herein, inspired by the Janus wettability of lotus leaves, we have constructed a bioinspired hydrophilic-hydrophobic Janus hybrid system of carbonized carrot powder (CC powder)-modified cotton cloth with Nafion coating on one side (cotton cloth-NCC) for highly efficient solar steam generation. In cotton cloth-NCC, CC powder functions as a light absorber to achieve high light absorption, whereas the hydrophilic cotton cloth ensures efficient water transport. Read More

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A brain-actuated robotic arm system using non-invasive hybrid brain-computer interface and shared control strategy.

J Neural Eng 2021 Apr 16. Epub 2021 Apr 16.

University of Bath, Claverton Down, Bath, Bath, Somerset, BA2 7AY, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

The electroencephalography (EEG)-based brain-computer interfaces (BCIs) have been used in the control of robotic arms. The performance of non-invasive BCIs may not be satisfactory due to the poor quality of EEG signals, so the shared control strategies were tried as an alternative solution. However, most of the existing shared control methods set the arbitration rules manually, which highly depended on the specific tasks and developer's experience. Read More

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Decoding molecular markers and transcriptional circuitry of naive and primed states of human pluripotency.

Stem Cell Res 2021 Apr 8;53:102334. Epub 2021 Apr 8.

Centre of Bioinformatics, Institute of Interdisciplinary Studies, University of Allahabad, Prayagraj 211002, India. Electronic address:

Pluripotent stem cells (PSCs) have been observed to occur in two distinct states - naive and primed. Both naive and primed state PSCs can give rise to tissues of all the three germ layers in vitro but differ in their potential to generate germline chimera in vivo. Understanding the molecular mechanisms that govern these two states of pluripotency in human can open a plethora of opportunities for studying early embryonic development and in biomedical applications. Read More

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Zinc(II)-Dipicolylamine Analogs Mediated PEI1.8k/pDNA Vector: Effect of Ligand Structure on the Gene Transport Process.

Macromol Biosci 2021 Apr 16:e2100048. Epub 2021 Apr 16.

Key Laboratory, of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China.

Zinc ion complexes of dipicolylamine analogs, due to the strong synergistic effect between the Zn complex of containing polypyridine derivatives and polycations in each key step of pDNA transport, have been used as the third component to mediate polyethyleneimine with molecular weight 1.8 kDa (PEI1.8k)/DNA gene delivery system. Read More

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Programming Colloidal Self-Assembled Patterns (cSAPs) into Thermo-Responsible Hybrid Surfaces for Controlling Human Stem Cells and Macrophages.

ACS Appl Mater Interfaces 2021 Apr 16. Epub 2021 Apr 16.

Shenzhen Key Laboratory of Biomimetic Materials and Cellular Immunomodulation, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.

Hybrid surfaces with tunable topography, chemistry, and stiffness have potential to rebuild native extracellular matrix (ECM) and manipulate cell behavior in vitro. However, the fabrication of controllable hybrid surfaces is still challenging. In this study, colloidal self-assembly technology was used to program particles into highly ordered structures with hybrid chemistry and stiffness at biointerfaces. Read More

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A Protocol for the Diagnosis of Autism Spectrum Disorder Structured in Machine Learning and Verbal Decision Analysis.

Comput Math Methods Med 2021 30;2021:1628959. Epub 2021 Mar 30.

University of Fortaleza (UNIFOR)-Graduate Program in Applied Informatics, Av. Washington Soares, 1321-Bl J Sl 30-60.811-905 Fortaleza, Brazil.

Autism Spectrum Disorder is a mental disorder that afflicts millions of people worldwide. It is estimated that one in 160 children has traces of autism, with five times the higher prevalence in boys. The protocols for detecting symptoms are diverse. Read More

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Genetic Gains in Pearl Millet in India: Insights Into Historic Breeding Strategies and Future Perspective.

Front Plant Sci 2021 30;12:645038. Epub 2021 Mar 30.

SeedWorks International Pvt Ltd, Hyderabad, India.

Pearl millet ( R. Br.) is an important staple and nutritious food crop in the semiarid and arid ecologies of South Asia (SA) and Sub-Saharan Africa (SSA). Read More

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Lipid-Polymer Hybrid Nanoparticle-Based Combination Treatment with Cisplatin and EGFR/HER2 Receptor-Targeting Afatinib to Enhance the Treatment of Nasopharyngeal Carcinoma.

Onco Targets Ther 2021 9;14:2449-2461. Epub 2021 Apr 9.

Department of Ear-Nose-Throat (ENT), The Second Hospital of Tianjin Medical University, Tianjin, 300211, People's Republic of China.

Purpose: Nasopharyngeal carcinoma (NPC) is one of the most prevalent carcinomas among the Cantonese population of South China and Southeast Asia (responsible for 8% of all cancers in China alone). Although concurrent platinum-based chemotherapy and radiotherapy have been successful, metastatic NPC remains difficult to treat, and the failure rate is high.

Methods: Thus, we developed stable lipid-polymer hybrid nanoparticles (NPs) containing cisplatin (CDDP) and afatinib (AFT); these drugs act synergistically to counter NPC. Read More

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Influence of Locomotion Therapy With the Wearable Cyborg HAL on Bladder and Bowel Function in Acute and Chronic SCI Patients.

Global Spine J 2021 Apr 16:21925682211003851. Epub 2021 Apr 16.

Department of Spinal Cord Injuries, BG University Hospital Bergmannsheil, Bochum, Germany.

Study Design: Retrospective survey.

Objectives: Purpose of this study was to explore whether bowel and bladder management can be influenced by locomotion therapy with HAL Robot Suit.

Methods: 35 subjects with acute (< one year since injury, n = 13) or chronic (> one year since injury, n = 22) incomplete paraplegia (American Spinal Injury Association Impairment Scale (AIS) B, n = 1 / AIS C, n = 22 / AIS D, n = 7) or complete paraplegia (AIS A, n = 5) with zones of partial preservation (ZPP) participated. Read More

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Blue/yellow emissive carbon dots coupled with curcumin: a hybrid sensor toward fluorescence turn-on detection of fluoride ion.

J Hazard Mater 2021 Jun 19;411:125184. Epub 2021 Jan 19.

School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, China; Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Ningbo University, Ningbo 315211, China; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. Electronic address:

Trace detection of fluoride ion has gained increasing attention due to fluoride's close association with biological and environmental processes. Herein, we construct a novel hybrid nanosystem consisting of carbon dots and curcumin for sensitive and selective sensing of F. Carbon dots are synthesized by hydrothermal treatment of 2,3-diaminopyridine and selenourea in hydrochloric acid. Read More

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Study of cuffless blood pressure estimation method based on multiple physiological parameters.

Physiol Meas 2021 Apr 15. Epub 2021 Apr 15.

College of Biomedical Engineering and Instrument Science, Zhejiang University, Zhejiang Province ZheDa road 38#, Hangzhou, Zhejiang, 310027, CHINA.

Objective: Non-invasive blood pressure measurement technologies have been widely studied, but they still have the disadvantages of low accuracy, require frequent calibration and limited subjects. This work considers the regulation of vascular activity by the sympathetic nervous system and proposes a method for estimating blood pressure using multiple physiological parameters.

Approach: The parameters used in the model consist Heart Rate Variability(HRV), pulse transit time(PTT) and pulse wave morphology features extracted from ECG and PPG signals. Read More

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Photo generated charge transport studies of defects-induced shuttlecock-shaped ZnO/Ag hybrid nanostructures.

Nanotechnology 2021 Apr 15. Epub 2021 Apr 15.

Department of Physics and Astrophysics, Delhi University, Delhi, INDIA.

We report the stimulating effects of interfacial charge transfer process between spherical Ag nanoparticles and shuttlecock-shaped ZnO nanostructures observed by UV-visible spectroscopy and X-ray absorption spectroscopy. In specific, ZnO nanorods and shuttlecock-shaped ZnO/Ag nanostructures were developed using a simple chemical colloidal method and characterized for structural variations using XRD. The observed red shift in plasmonic peak and the increase in Urbach energy signify interfacial interactions and increased randomness in the hybrid ZnO/Ag nanostructures. Read More

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COVID-19: Impact on Orthopaedic Graduate Medical Education in the U.S.: AOA Critical Issues Symposium.

J Bone Joint Surg Am 2021 Apr 15. Epub 2021 Apr 15.

Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, Florida.

Abstract: The COVID-19 crisis has challenged the U.S. health-care system in a variety of ways, including how we teach and train orthopaedic surgery residents and fellows. Read More

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A Hybrid DCNN-SVM Model for Classifying Neonatal Sleep and Wake States Based on Facial Expression in Video.

IEEE J Biomed Health Inform 2021 Apr 15;PP. Epub 2021 Apr 15.

Sleep is a natural phenomenon controlled by the central nervous system. The sleep-wake pattern, which functions as an essential indicator of neurophysiological organization in the neonatal period, has profound meaning in the prediction of cognitive diseases and brain maturity. In recent years, unobtrusive sleep monitoring and automatic sleep staging have been intensively studied for adults, but much less for neonates. Read More

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Polyaniline-Coated MOFs Nanorod Arrays for Efficient Evaporation-Driven Electricity Generation and Solar Steam Desalination.

Adv Sci (Weinh) 2021 Apr 1;8(7):2004552. Epub 2021 Feb 1.

State Key Laboratory of Silicon Materials School of Materials Science and Engineering ERC of Membrane and Water Treatment Zhejiang University Hangzhou 310027 P. R. China.

Though evaporation-driven electricity generation has emerged as a novel eco-friendly energy and attracted intense interests, it is typically demonstrated in pure water or a very low salt concentration. Integrating evaporation-driven electricity generation and solar steam desalination simultaneously should be more promising. Herein, a polyaniline coated metal-organic frameworks (MOFs) nanorod arrays membrane is synthesized which inherits the merits of both polyaniline and MOFs, demonstrating nice stability, good interfacial solar steam desalination, and evaporation-driven electricity generation. Read More

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Postsurgical Prosthetic Rehabilitation after Mandibular Ameloblastoma Resection: A 7-Year Follow-Up Case Report.

Case Rep Dent 2021 28;2021:5593973. Epub 2021 Mar 28.

Department of Odontostomatology, Faculty of Medicine and Health Sciences (Dentistry), University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.

Ameloblastomas are benign but locally invasive odontogenic tumors most frequently located in the mandible. The gold standard of treatment is the surgical resection of the tumor with safety margins. Postsurgical defects generate a significant morbidity that needs reconstruction and oral rehabilitation to restore the oral functions. Read More

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Clinical Influencing Factors of Acute Myocardial Infarction Based on Improved Machine Learning.

J Healthc Eng 2021 27;2021:5569039. Epub 2021 Mar 27.

Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.

At present, there is no method to predict or monitor patients with AMI, and there is no specific treatment method. In order to improve the analysis of clinical influencing factors of acute myocardial infarction, based on the machine learning algorithm, this paper uses the K-means algorithm to carry out multifactor analysis and constructs a hybrid model combined with the ART2 network. Moreover, this paper simulates and analyzes the model training process and builds a system structure model based on the KNN algorithm. Read More

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A dynamic center and multi threshold point based stable feature extraction network for driver fatigue detection utilizing EEG signals.

Cogn Neurodyn 2021 Apr 25;15(2):223-237. Epub 2020 May 25.

College of Engineering, Department of Computer Science, Effat University, Jeddah, 21478 Saudi Arabia.

Driver fatigue is the one of the main reasons of the traffic accidents. The human brain is a complex structure, whose function can be evaluated with electroencephalogram (EEG). Automated driver fatigue detection utilizing EEG decreases the incidence probability of related traffic accidents. Read More

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Silica optical fiber integrated with two-dimensional materials: towards opto-electro-mechanical technology.

Light Sci Appl 2021 Apr 14;10(1):78. Epub 2021 Apr 14.

College of Engineering and Applied Sciences, National Laboratory of Solid State Microstructures and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, 210093, China.

In recent years, the integration of graphene and related two-dimensional (2D) materials in optical fibers have stimulated significant advances in all-fiber photonics and optoelectronics. The conventional passive silica fiber devices with 2D materials are empowered for enhancing light-matter interactions and are applied for manipulating light beams in respect of their polarization, phase, intensity and frequency, and even realizing the active photo-electric conversion and electro-optic modulation, which paves a new route to the integrated multifunctional all-fiber optoelectronic system. This article reviews the fast-progress field of hybrid 2D-materials-optical-fiber for the opto-electro-mechanical devices. Read More

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Solid-Binding Proteins: Bridging Synthesis, Assembly, and Function in Hybrid and Hierarchical Materials Fabrication.

Annu Rev Chem Biomol Eng 2021 Apr 14. Epub 2021 Apr 14.

Department of Chemical Engineering, University of Washington, Seattle, Washington 98115, USA; email:

There is considerable interest in the development of hybrid organic-inorganic materials because of the potential for harvesting the unique capabilities that each system has to offer. Proteins are an especially attractive organic component owing to the high amount of chemical information encoded in their amino acid sequence, their amenability to molecular and computational (re)design, and the many structures and functions they specify. Genetic installation of solid-binding peptides (SBPs) within protein frameworks affords control over the position and orientation of adhesive and morphogenetic segments, and a path toward predictive synthesis and assembly of functional materials and devices, all while harnessing the built-in properties of the host scaffold. Read More

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A new approach: information gain algorithm-based k-nearest neighbors hybrid diagnostic system for Parkinson's disease.

Phys Eng Sci Med 2021 Apr 14. Epub 2021 Apr 14.

Electrical-Electronics Engineering Department, Hakkari University, 30000, Hakkari, Turkey.

Parkinson's disease (PD) is a slow and insidiously progressive neurological brain disorder. The development of expert systems capable of automatically and highly accurately diagnosing early stages of PD based on speech signals would provide an important contribution to the health sector. For this purpose, the Information Gain Algorithm-based K-Nearest Neighbors (IGKNN) model was developed. Read More

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PaccMann: De novo generation of hit-like anticancer molecules from transcriptomic data via reinforcement learning.

iScience 2021 Apr 5;24(4):102269. Epub 2021 Mar 5.

IBM Research Europe, 8803 Rüschlikon, Switzerland.

With the advent of deep generative models in computational chemistry, drug design is undergoing an unprecedented transformation. Although deep learning approaches have shown potential in generating compounds with desired chemical properties, they disregard the cellular environment of target diseases. Bridging systems biology and drug design, we present a reinforcement learning method for de novo molecular design from gene expression profiles. Read More

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Effect of supercapacitors on the operation of an air-cooled hydrogen fuel cell.

Heliyon 2021 Mar 23;7(3):e06569. Epub 2021 Mar 23.

DST HySA Infrastructure Center of Competence, Faculty of Engineering, North West University, Potchefstroom 2520, South Africa.

One of the greatest challenges associated with efficient energy use in unmanned aerial vehicles (drones) is that of the energy storage systems - more specifically it's weight and capacity. Current hydrogen fuel cell drones have very promising flight durations, but have a low power density thus performing poorly at peak power demands. Supercapacitors are known to have high power densities and respond significantly well to peak power demands. Read More

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Bio-convective and chemically reactive hybrid nanofluid flow upon a thin stirring needle with viscous dissipation.

Sci Rep 2021 Apr 13;11(1):8066. Epub 2021 Apr 13.

Program in Applied Statistics, Department of Mathematics and Computer Science, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, Thanyaburi, Pathumthani, 12110, Thailand.

In this work, the thermal analysis for bio-convective hybrid nanofluid flowing upon a thin horizontally moving needle is carried out. The chemical reaction and viscous dissipation has also considered for flow system in the presence of microorganism. The hybrid nanoparticles comprising of Copper [Formula: see text] and Alumina [Formula: see text] are considered for current flow problem. Read More

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Comparison of bicortical, miniplate and hybrid fixation techniques in mandibular advancement and counterclockwise rotation: A finite element analysis study.

J Stomatol Oral Maxillofac Surg 2021 Apr 10. Epub 2021 Apr 10.

Professor, Marmara University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Istanbul, Turkey. Electronic address:

Objective: This study aims to evaluate biomechanical stability and stress distribution of five different fixation types with finite element analysis using 10-mm advancement with or without counterclockwise rotation of the mandible.

Materials And Methods: After sagittal split osteotomy, 10-mm advancement was performed in the first group and 10-mm advancement and 10-degree counterclockwise rotation were performed in the second group. One miniplate (M-1), two-miniplate (M-2), one miniplate and a bicortical screw (H), L-shaped bicortical screw (B-1), and inverted L-shaped bicortical screw (B-2) systems were placed. Read More

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COVID-19 information retrieval with deep-learning based semantic search, question answering, and abstractive summarization.

NPJ Digit Med 2021 Apr 12;4(1):68. Epub 2021 Apr 12.

Salesforce Research, Palo Alto, CA, USA.

The COVID-19 global pandemic has resulted in international efforts to understand, track, and mitigate the disease, yielding a significant corpus of COVID-19 and SARS-CoV-2-related publications across scientific disciplines. Throughout 2020, over 400,000 coronavirus-related publications have been collected through the COVID-19 Open Research Dataset. Here, we present CO-Search, a semantic, multi-stage, search engine designed to handle complex queries over the COVID-19 literature, potentially aiding overburdened health workers in finding scientific answers and avoiding misinformation during a time of crisis. Read More

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Development and characterization of self-etching adhesives doped with 45S5 and niobophosphate bioactive glasses: Physicochemical, mechanical, bioactivity and interface properties.

Dent Mater 2021 Apr 10. Epub 2021 Apr 10.

Discipline of Dental Materials, School of Dentistry, Federal University of Maranhão (UFMA), Av. dos Portugueses, 1966, 65080-805 São Luís, Maranhão, Brazil. Electronic address:

Objective: The aim of study was to develop and characterize experimental bioactive glasses (45S5 and niobophosphate bioactive glass (NbG)) and evaluate the effects of their addition in self-etching adhesive systems on physicochemical, mechanical, and bioactive properties, microtensile bond strength (μTBS), and nanoleakage (NL).

Methods: Two-step self-etching adhesive systems containing 5, 10, and 20 wt.% of 45S5 and NbG bioactive glasses were developed. Read More

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