10 results match your criteria hu-b hu-a

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N-Terminal Extensions Appear to Frustrate HU Heterodimer Formation by Strengthening Intersubunit Contacts and Blocking the Formation of a Heterotetrameric Intermediate.

Biochemistry 2021 Jun 21;60(23):1836-1852. Epub 2021 May 21.

Centre for Protein Science, Design and Engineering (CPSDE), Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector-81, SAS Nagar, Punjab 140306, India.

HU is a bacterial nucleoid-associated protein. Two homologues, known as HU-A, and HU-B, are found in within which the early, late, and stationary phases of growth are dominated by HU-AA, HU-BB, and HU-AB dimers, respectively. Here, using genetic manipulation, mass spectrometry, spectroscopy, chromatography, and electrophoretic examination of glutaraldehyde-mediated cross-linking of subunits, in combination with experiments involving mixing, co-expression, unfolding, and refolding of HU chains, we show that the spontaneous formation of HU-AB heterodimers that is reported to occur upon mixing of wild-type HU-AA and HU-BB homodimers does not occur if chains possess N-terminal extensions. Read More

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HU-AB simulacrum: Fusion of HU-B and HU-A into HU-B-A, a functional analog of the Escherichia coli HU-AB heterodimer.

Biochem Biophys Res Commun 2021 Jun 5;560:27-31. Epub 2021 May 5.

Centre for Protein Science, Design and Engineering (CPSDE), Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector-81, SAS Nagar, Punjab, 140306, India. Electronic address:

In enteric bacteria such as Escherichia coli, there are two homologs of the DNA-binding nucleoid associated protein (NAP) known as HU. The two homologs are known as HU-A and HU-B, and exist either in the form of homodimers (HU-AA, or HU-BB) or as heterodimers (HU-AB), with different propensities to form higher-order oligomers. The three different dimeric forms dominate different stages of bacterial growth, with the HU-AB heterodimer dominating cultures in the stationary phase. Read More

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Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial.

J Clin Anesth 2021 May 6;69:110150. Epub 2021 Jan 6.

Department of Anesthesiology, Shenzhen People's Hospital, Shenzhen, China; The Second Clinical Medical College, Jinan University, Shenzhen, China; First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, China. Electronic address:

Study Objective: This study aimed to evaluate the effects of low versus high mean arterial pressure (MAP) levels on the incidence of postoperative delirium during non-cardiothoracic surgery in older patients.

Design: Multicenter, randomized, parallel-controlled, open-label, and assessor-blinded clinical trial.

Setting: University hospital. Read More

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Comparison of the effect of high versus low mean arterial pressure levels on clinical outcomes and complications in elderly patients during non-cardiothoracic surgery under general anesthesia: study protocol for a randomized controlled trial.

Trials 2017 Nov 21;18(1):554. Epub 2017 Nov 21.

Clinical Medical Research Center, The Second Clinical Medicine College, Jinan University, Shenzhen, 518001, China.

Background: Intraoperative blood pressure (BP) is a concern in daily clinic anesthesia and contributes to the differences in clinical outcome. We conducted a randomized controlled trial (RCT) to compare the effect of high vs. low mean arterial pressure (MAP) levels on clinical outcomes and complications in elderly patients under general anesthesia (GA). Read More

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November 2017

Relationship between low tube voltage (70 kV) and the iodine delivery rate (IDR) in CT angiography: An experimental in-vivo study.

PLoS One 2017 20;12(3):e0173592. Epub 2017 Mar 20.

MR and CT Contrast Media Research, Bayer Healthcare, Berlin, Germany.

Objective: Very short acquisition times and the use of low-kV protocols in CTA demand modifications in the contrast media (CM) injection regimen. The aim of this study was to optimize the use of CM delivery parameters in thoraco-abdominal CTA in a porcine model.

Materials And Methods: Six pigs (55-68 kg) were examined with a dynamic CTA protocol (454 mm scan length, 2. Read More

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Distribution and diversity of anaerobic ammonium-oxidizing bacteria in the sediments of the Qiantang River.

Environ Microbiol Rep 2012 Oct 19;4(5):540-7. Epub 2012 Jun 19.

Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China.

Anaerobic ammonium oxidation (anammox) is an important process in the marine nitrogen cycle. However, little is known about the distribution, diversity and abundance of anammox bacteria in inland river ecosystems. Here, we found the presence of diverse anammox bacteria in a freshwater river - the Qiantang River, Zhejiang Province (China). Read More

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October 2012

Metabolic properties of a mixed culture of aerobic ammonia oxidizers and its optimal reaction conditions.

Bioresour Technol 2012 Jan 31;104:571-8. Epub 2011 Oct 31.

Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China.

The aerobic ammonia oxidation is an important process for nitrogen removal from wastewater with high ammonia concentration. Here, we investigated the metabolic properties of a mixed culture of aerobic ammonia oxidizers and determined its optimal reaction conditions. The maximum specific rate of NO(2)(-)-N formation of the culture was 14. Read More

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January 2012

Respiration induced heart motion and indications of gated delivery for left-sided breast irradiation.

Int J Radiat Oncol Biol Phys 2012 Apr 12;82(5):1605-11. Epub 2011 Apr 12.

Department of Radiation Oncology, University of Colorado Denver, Aurora, CO, USA.

Purpose: To investigate respiration-induced heart motion for left-sided breast irradiation using a four-dimensional computed tomography (4DCT) technique and to determine novel indications to assess heart motion and identify breast patients who may benefit from a gated treatment.

Methods And Materials: Images of 4DCT acquired during free breathing for 20 left-sided breast cancer patients, who underwent whole breast irradiation with or without regional nodal irradiation, were analyzed retrospectively. Dose distributions were reconstructed in the phases of 0%, 20%, and 50%. Read More

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Multidetector CT imaging of pleura: comparison of two contrast infusion protocols.

Br J Radiol 2011 Sep 15;84(1005):796-9. Epub 2010 Dec 15.

Department of Radiology, Glenfield Hospital, University Hospitals of Leicester, Leicester, UK.

Objectives: Imaging of the pleura by multidetector CT (MDCT) can be challenging. There is no clear evidence or guidelines on contrast infusion parameters for imaging pleura. We compared two contrast protocols for assessing pleural pathology on MDCT. Read More

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September 2011

Quantitative comparison of stability of ANAMMOX process in different reactor configurations.

Bioresour Technol 2008 Apr 25;99(6):1603-9. Epub 2007 May 25.

Department of Environmental Engineering, Zhejiang University, Hangzhou, PR China.

A new stability evaluating system for ANAMMOX comprising three instability indices i.e. coefficient of variation ratio, coefficient of range ratio and coefficient of regression function derivative was established. Read More

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