208,587 results match your criteria hospital stay


Remdesivir Efficacy in COVID-19 Treatment: A Randomized Controlled Trial.

Am J Trop Med Hyg 2021 Sep 10. Epub 2021 Sep 10.

Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University, Tanta, Egypt.

To date, no antiviral therapy has shown proven clinical effectiveness in treating patients with COVID-19. We assessed the efficacy of remdesivir in hospitalized Egyptian patients with COVID-19. Patients were randomly assigned at a 1:1 ratio to receive either remdesivir (200 mg on the first day followed by 100 mg daily for the next 9 days intravenously infused over 30-60 minutes) in addition to standard care or standard care alone. Read More

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September 2021

Assessing the effects of non-pharmaceutical interventions on SARS-CoV-2 transmission in Belgium by means of an extended SEIQRD model and public mobility data.

Epidemics 2021 Oct 2;37:100505. Epub 2021 Oct 2.

KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, Coupure links 653, 9000 Gent, Belgium.

We present a compartmental extended SEIQRD metapopulation model for SARS-CoV-2 spread in Belgium. We demonstrate the robustness of the calibration procedure by calibrating the model using incrementally larger datasets and dissect the model results by computing the effective reproduction number at home, in workplaces, in schools, and during leisure activities. We find that schools and home contacts are important transmission pathways for SARS-CoV-2 under lockdown measures. Read More

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October 2021

Altered mental status predicts length of stay but not death in a community-based cohort of hospitalized COVID-19 patients.

Clin Neurol Neurosurg 2021 Oct 7;210:106977. Epub 2021 Oct 7.

Department of Neurology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Introduction: Altered Mental Status (AMS) is a common neurological complication in patients hospitalized with the diagnosis of COVID-19 (Umapathi et al., 2020; Liotta et al., 2020). Read More

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October 2021

Vasopressin to control blood loss during hysterectomy: a systematic review and meta-analysis of randomized controlled trials.

J Minim Invasive Gynecol 2021 Oct 11. Epub 2021 Oct 11.

Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia. Electronic address:

Objective: Minimizing intraoperative blood loss during hysterectomy is crucial to lessen associated perioperative morbidity. The aim of this investigation is to conduct a systematic review and meta-analysis of all randomized controlled trials (RCTs) that compared vasopressin versus normal saline in controlling intraoperative blood loss during hysterectomy.

Data Sources: We screened five major databases (PubMed, Scopus, Web of Science, Embase, and the Cochrane Central Register of Controlled Trials) from inception till July 18, 2021. Read More

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October 2021

Survival and Surgical Approach among Women with Advanced Ovarian Cancer Treated with Neoadjuvant Chemotherapy.

J Minim Invasive Gynecol 2021 Oct 11. Epub 2021 Oct 11.

Northwestern University Feinberg School of Medicine, Chicago, IL; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Surgical Outcomes and Quality Improvement Center, Institute for Public Health in Medicine, Chicago, IL.

Study Objective: To evaluate the effect of surgical approach on overall survival (OS) for women with advanced, epithelial ovarian cancer (EOC) following neoadjuvant chemotherapy (NACT) and determine the socio-demographic and clinical factors associated with surgical approach.

Design: The primary exposure was surgical approach to interval cytoreduction, minimally invasive versus open, and was evaluated by intention to treat. Primary outcome was OS. Read More

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October 2021

Is Cleft Lip or Palate a Risk Factor for Perioperative Complications in Orthognathic Surgery?

J Oral Maxillofac Surg 2021 Sep 17. Epub 2021 Sep 17.

Associate Professor, Oral & Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA. Electronic address:

Purpose: Perioperative outcomes following cleft orthognathic surgery are not well established. The purpose of this study was to compare the incidence of orthognathic specific complications (OSCs) in patients with and without cleft lip and/or palate.

Methods: The American College of Surgeons National Surgical Quality Improvement Program adult and pediatric databases were used to enroll patients undergoing orthognathic surgery. Read More

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September 2021

Severity of Inpatient Hospitalizations Among Undocumented Immigrants and Medi-Cal Patients in a Los Angeles, California, Hospital: 2019.

Am J Public Health 2021 Oct 14:e1-e8. Epub 2021 Oct 14.

Annie Ro is with the Department of Health, Society, and Behavior at the University of California, Irvine. At the time the study was conducted, Helen W. Yang was a chief resident in Internal Medicine at the Keck School of Medicine of University of Southern California (USC), Los Angeles. Senxi Du is a medical student at the Keck School of Medicine of Medicine. Courtney L. Hanlon is with the Los Angeles County and USC Medical Center, Los Angeles. Andrew Shane Young is with the Division of Geriatric, Hospital, Palliative, and General Internal Medicine, Department of Medicine, Keck School of Medicine.

To compare the severity of inpatient hospitalizations between undocumented immigrants and Medi-Cal patients in a large safety-net hospital in Los Angeles, California. We conducted a retrospective analysis of all 2019 inpatient stays at a Los Angeles hospital (n = 22 480), including patients of all races/ethnicities. We examined 3 measures by using insurance status to approximate immigration status: illness severity, length of hospital stay, and repeat hospitalizations. Read More

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October 2021

Effects of different anesthesia methods on maternal and neonatal outcomes in pregnant patients with pulmonary arterial hypertension: a meta-analysis.

Arch Gynecol Obstet 2021 Oct 14. Epub 2021 Oct 14.

Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.

Purpose: To investigate the effects of different anesthesia methods on maternal and neonatal outcomes in pregnant patients with pulmonary arterial hypertension (PAH).

Methods: We searched PubMed, Excerpta Medica Database (EMBASE), Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Wanfang and QVIP for investigating the effects of general anesthesia (GA) and local anesthesia (LA) in pregnant patients with PAH. Results were expressed as weighted mean difference (WMD) or risk ratio (RR) with 95% confidence intervals (CIs). Read More

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October 2021

Changes in burn wound microbiology profile over 14 years of an adult tertiary burn center.

J Burn Care Res 2021 Oct 14. Epub 2021 Oct 14.

Scar Free Foundation Birmingham Centre for Burns Research, University Hospitals Birmingham Foundation Trust, Mindelsohn Way, Birmingham, B15 2WB, UK.

Burn wound colonization can progress to invasive infection. During 14 years of this study, the burn center was relocated to a center with improved infrastructure. This study investigates the association that infrastructure, geography and time may have on colonization. Read More

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October 2021

Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults: A Randomized Clinical Trial.

JAMA Netw Open 2021 Oct 1;4(10):e2128886. Epub 2021 Oct 1.

Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei, China.

Importance: Postoperative ileus is common after abdominal surgery, and small clinical studies have reported that intraoperative administration of dexmedetomidine may be associated with improvements in postoperative gastrointestinal function. However, findings have been inconsistent and study samples have been small. Further examination of the effects of intraoperative dexmedetomidine on postoperative gastrointestinal function is needed. Read More

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October 2021

Non-robotized frameless stereotactic magnetic resonance guided laser interstitial thermal therapy for hypothalamic hamartoma: preliminary results of 2 cases and review of the literature.

J Neurosurg Sci 2021 Oct 14. Epub 2021 Oct 14.

Division of Neurosurgery, IRCCS Istituto Giannina Gaslini, Genova, Italy.

Background: Various strategies have been proposed for the treatment of gelastic seizures due to hypothalamic hamartomas (HH), advancing from surgical removal techniques toward functional disconnection strategies. One of the most recent procedure is the Magnetic Resonance guided Laser Interstitial Thermal Therapy (MRg-LITT), which has progressively proved to be a safe and effective technique for hamartomas ablation. In this paper, the authors' preliminary experience with the first two patients treated with this technique in Italy is presented, in order to underline the feasibility of a pure non robotized frameless technique (FS MRg-LITT) while confirming the procedure effectiveness on seizure control. Read More

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October 2021

Should intravenous acetaminophen be considered for post craniotomy pain management? A Meta-analysis of randomized controlled trials.

J Neurosurg Sci 2021 Oct 14. Epub 2021 Oct 14.

Faculty of Medicine, Zagazig University, Zagazig, El-Sharkia, Egypt -

Introduction: Post craniotomy pain management with opioids is challenging due to their side effects, which might mask neurological deterioration symptoms. Recently, intravenous (IV) acetaminophen has been tested in this population. This meta-analysis aimed to synthesize evidence from published randomized controlled trials (RCTs) about the efficacy of IV acetaminophen in reducing pain scores in postoperative craniotomy patients. Read More

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October 2021

Title: Persistence of Sleep Disturbance among Post-Covid Patients: Findings from a two-month follow-up study in a Bangladeshi cohort.

J Med Virol 2021 Oct 14. Epub 2021 Oct 14.

Head and Professor of Medicine, Universal Medical College Research Center, Dhaka, Bangladesh.

Objective: To evaluate the persistence and factors associated with sleep disturbances among COVID-19 patients with a history of sleep disturbances two months after discharge from the hospital METHODOLOGY: A total of 400 patients admitted at Dhaka Medical College Hospital during July and August were diagnosed as suffering from sleep disturbances during their hospital stay using a standardized scale. They were followed up two months later through telephone, and a total of 322 participants were interviewed (excluding 63 non-responders and five deceased) regarding the persistence of disturbances in sleep through a structured questionnaire. Patient demographic, clinical, and epidemiological data including history regarding in-hospital sleep disturbance were retrieved from hospital treatment sheets. Read More

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October 2021

What happens to patients undergoing cancer surgery with psychiatric comorbidities?: A nationwide retrospective cohort study.

J Surg Oncol 2021 Oct 14. Epub 2021 Oct 14.

Department of Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA.

Objective: We aimed to describe the surgical outcomes and readmissions rates in patients with psychological comorbidities who underwent surgical intervention for cancer.

Background: The Hospital Readmission Reduction Program, a campaign by the Affordable Care Act, penalizes hospitals for greater readmission rates. One prevalent patient risk factor associated with hospital readmission is a comorbid psychiatric condition. Read More

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October 2021

Effects of Dipeptidyl Peptidase-4 Inhibitors and Sulfonylureas on Cognitive and Physical Function in Nursing Home Residents.

Diabetes Obes Metab 2021 Oct 13. Epub 2021 Oct 13.

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI.

Aims: Dipeptidyl peptidase-4 inhibitors (DPP4Is) may mitigate hypoglycemia-mediated declines in cognitive and physical functioning compared to sulfonylureas (SUs), yet comparative studies are unavailable among older adults, especially nursing home (NH) residents. We evaluated the effects of DPP4Is versus SUs on cognitive and physical functioning among NH residents.

Materials And Methods: This new-user cohort study included long-stay NH residents aged ≥65 years from the 2007-2010 national US Minimum Data Set (MDS) clinical assessments and linked Medicare claims. Read More

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October 2021

Placement of Simultaneous Inferior Vena Cava Filter During Emergent Open Pulmonary Thromboembolectomy.

Surg Technol Int 2021 10 13;39. Epub 2021 Oct 13.

Thoracic and Cardiovascular Surgery, Baylor Scott White Clinic, Temple, Texas.

Background: This study retrospectively reviewed results of simultaneous (SIM) inferior vena cava (IVC) filter and separate (SEP) IVC filter placement with open pulmonary thromboembolectomy (PTE) in pulmonary embolism and its clinical outcomes.

Materials And Methods: From November 2006 to May 2014, 23 patients (14 females and 9 males; median age 58 years; range, 21-88 years) underwent emergent PTE for submassive (12) or massive (11) pulmonary embolism (PE). All had a preoperative computed tomography (CT) scan and echocardiography consistent with right ventricular (RV) strain. Read More

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October 2021

Image-guided combined ablation and resection in thoracic surgery for the treatment of multiple pulmonary metastases: A preliminary case series.

JTCVS Tech 2021 Oct 13;9:156-162. Epub 2021 Mar 13.

Department of Thoracic Surgery, University Hospital Southampton, Southampton, United Kingdom.

Objectives: To demonstrate the feasibility and preliminary outcomes of a novel hybrid technique combining percutaneous microwave ablation and wire-assisted wedge resection for patients with multiple pulmonary metastases using intraoperative imaging.

Methods: We describe our technique and present a retrospective case series of 4 patients undergoing iCART at our institution between August 2018 and January 2020. Procedures were performed in a hybrid operating suite using the ARTIS Pheno cone beam computerized tomography scanner (Siemens Healthineers, Erlangen, German). Read More

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October 2021

Robotics-assisted epicardial left atrial appendage clip exclusion.

JTCVS Tech 2021 Oct 21;9:59-68. Epub 2021 Jul 21.

Department of Anesthesiology, Health First Holmes Regional Medical Center, Melbourne, Fla.

Objectives: We demonstrate the feasibility and safety of robotics-assisted left atrial appendage clip exclusion in clinical practice.

Methods: Analysis of a single center robotics-assisted left atrial appendage clip exclusion experience using an epicardial linear clip device in patients with atrial fibrillation with high-risk of thromboembolic stroke and intolerance to oral anticoagulants.

Results: During the period from December 2017 to September 2020, we performed 42 robotics-assisted left atrial appendage clip exclusions in response to increased risk of bleeding in patients with atrial fibrillation and intolerance to oral anticoagulants. Read More

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October 2021

Survival impact of bowel resection at the time of interval cytoreductive surgery for advanced ovarian cancer.

Gynecol Oncol Rep 2021 Nov 25;38:100870. Epub 2021 Sep 25.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA.

Objectives: To evaluate the impact of bowel resection at the time of interval cytoreductive surgery on survival.

Methods: We identified patients with advanced ovarian cancer who underwent neoadjuvant chemotherapy and interval cytoreductive surgery between 2008 and 2018 from a single-institution tumor registry. Kaplan-Meier survival analysis and Cox proportional hazards models were performed comparing patients who underwent bowel resection to those who did not. Read More

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November 2021

Impact of a Multiplex Polymerase Chain Reaction Panel on Duration of Empiric Antibiotic Therapy in Suspected Bacterial Meningitis.

Open Forum Infect Dis 2021 Oct 30;8(10):ofab467. Epub 2021 Sep 30.

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

Background: Multiplex polymerase chain reaction (PCR) panels allow for rapid detection or exclusion of pathogens causing meningitis and encephalitis (ME). The clinical impact of rapid multiplex PCR ME panel results on the duration of empiric antibiotic therapy is not well characterized.

Methods: We performed a retrospective prepost study at our institution that evaluated the clinical impact of a multiplex PCR ME panel among adults with suspected bacterial meningitis who received empiric antibiotic therapy and underwent lumbar puncture in the emergency department. Read More

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October 2021

Comparison of the Efficacy of ShuoTong Ureteroscopy and Simple Flexible Ureteroscopy in the Treatment of Unilateral Upper Ureteral Calculi.

Front Surg 2021 27;8:707022. Epub 2021 Sep 27.

The Key Laboratory of Urinary Tract Tumors and Calculi, Department of Urology Surgery, The First Affiliated Hospital, School of Medicine, Xiamen University, Xiamen, China.

ShuoTong ureteroscopy (Sotn-ureteroscopy, ST-URS), a new lithotripsy operation method developed on the basis of ureteroscopy, is widely used to treat ureteral stones in China. Its composition includes rigid ureteral access sheath, standard mirror, lithotripsy mirror, and ShuoTong perfusion aspirator (ST-APM). Here, we compared the efficacy and safety of the ST-URS and the flexible ureteroscope (F-URS) holmium laser lithotripsy in the treatment of unilateral upper ureteral calculi. Read More

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September 2021

The Effectiveness of Convalescent Plasma for the Treatment of Novel Corona Virus Disease 2019: A Systematic Review and Meta-Analysis.

Front Med (Lausanne) 2021 27;8:641429. Epub 2021 Sep 27.

Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.

Coronavirus disease 2019 (COVID-19), sweeping across the world, has created a worldwide pandemic. Effective treatments of COVID-19 are extremely urgent. To analyze the efficacy and safety of convalescent plasma (CCP) on patients with COVID-19. Read More

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September 2021

Impact of Acute Confusional State in Patients With COVID-19 and a Predictive Score.

Cureus 2021 Sep 28;13(9):e18360. Epub 2021 Sep 28.

Neurology, University of Texas Medical Branch at Galveston, Galveston, USA.

Background: Acute confusional state (ACS) in COVID-19 is shown to be associated with poor clinical outcomes.

Methods: We assessed the impact of ACS - defined as a documented deterioration of mental status from baseline on the alertness and orientation to time, place, and person - on inpatient mortality and the need for intensive care unit (ICU) transfer in inpatient admissions with active COVID-19 infection in a single-center retrospective cohort of inpatient admissions from a designated COVID-19 tertiary care center using an electronic health record system. Furthermore, we developed and validated a neurological history and symptom-based predictive score of developing ACS. Read More

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September 2021

The Effect on Length of Stay After Implementation of Discharging Low Acuity Patients From Triage.

Cureus 2021 Sep 1;13(9):e17640. Epub 2021 Sep 1.

Emergency Medicine, HCA Healthcare, Riverside Community Hospital, Riverside, USA.

Introduction Overcrowding in the emergency department is a complex and challenging issue across the nation. The increasing number of patients seeking care in the emergency department leads to overcrowding and therefore decreased available rooms and slower throughput. As part of a quality improvement project to improve throughput, we implemented a policy encouraging the discharge of non-emergent patients directly from triage. Read More

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September 2021

Awake Craniotomy for Resection of Cerebral Arteriovenous Malformation: Initial Experience From a Low- and Middle-Income Country.

Cureus 2021 Aug 31;13(8):e17596. Epub 2021 Aug 31.

Neurosurgery, Aga Khan University Hospital, Karachi, PAK.

Global health has shown progress over the years; however, neurosurgical care has not followed the same trajectory due to it being presumably resource intensive. Awake craniotomy (AC) is a neurosurgical technique that can improve neurological outcomes, can potentially reduce costs and hospital stay, and can be easily employed in low- and middle-income countries (LMICs). It has proven to be beneficial in surgical resection of tumors located in the critical areas of the brain, but there is limited literature to support AC for resection of arteriovenous malformations (AVM). Read More

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Early Psychiatric Consultation Is Associated With Decreased Cost and Length of Stay in the Patient Population at a Level I Trauma Center.

Cureus 2021 Aug 30;13(8):e17572. Epub 2021 Aug 30.

Department of Trauma/Acute and General Surgery, St. Joseph's Hospital and Medical Center, Phoenix, USA.

Introduction Psychiatric illness impacts nearly one-quarter of the US population. Few studies have evaluated the impact of psychiatric illness on in-hospital trauma patient care. In this study, we conducted a retrospective cohort study to evaluate hospital resource utilization for trauma patients with comorbid psychiatric illnesses. Read More

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Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis.

Sci Rep 2021 Oct 13;11(1):20333. Epub 2021 Oct 13.

Department of Critical Care Medicine, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, No. 16, Jichang Road, Baiyun District, Guangzhou, 510405, Guangdong Province, China.

Levosimendan and dobutamine are extensively used to treat sepsis-associated cardiovascular failure in ICU. Nevertheless, the role and mechanism of levosimendan in patients with sepsis-induced cardiomyopathy remains unclear. Moreover, previous studies on whether levosimendan is superior to dobutamine are still controversial. Read More

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October 2021

Effect of nocturnal oxygen therapy on exercise performance of COPD patients at 2048 m: data from a randomized clinical trial.

Sci Rep 2021 Oct 13;11(1):20355. Epub 2021 Oct 13.

Department of Respiratory Medicine, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

This trial evaluates whether nocturnal oxygen therapy (NOT) during a stay at 2048 m improves altitude-induced exercise intolerance in lowlanders with chronic obstructive pulmonary disease (COPD). 32 lowlanders with moderate to severe COPD, mean ± SD forced expiratory volume in the first second of expiration (FEV) 54 ± 13% predicted, stayed for 2 days at 2048 m twice, once with NOT, once with placebo according to a randomized, crossover trial with a 2-week washout period at < 800 m in-between. Semi-supine, constant-load cycle exercise to exhaustion at 60% of maximal work-rate was performed at 490 m and after the first night at 2048 m. Read More

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October 2021

A Retrospective Study of Postoperative Outcomes in 98 Patients Diagnosed with Gastrointestinal Stromal Tumor (GIST) of the Upper, Middle, and Lower Gastrointestinal Tract Between 2009 and 2019 at a Single Center in Poland.

Med Sci Monit 2021 Oct 14;27:e932809. Epub 2021 Oct 14.

Department of Gastrointestinal Surgery, Medical University of Silesia, Katowice, Poland.

BACKGROUND Gastrointestinal stromal tumors (GISTs) arise in the smooth muscle pacemaker interstitial cells of Cajal, or similar cells. The aim of this retrospective study between 2009 and 2019 from a single center in Poland was to assess the selected prognostic factors (location, tumor size, mitotic index, body mass index (BMI), length of hospital stay, age, sex, and coexistent neoplasm) and to investigate postoperative outcomes in 98 patients with GIST of the upper, middle, and lower gastrointestinal tract. MATERIAL AND METHODS Between 2009 and 2019, 98 patients (50 women and 48 men) with an average age of 63. Read More

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October 2021

Use of pacemaker in GBS dysautonomia.

BMJ Case Rep 2021 Oct 13;14(10). Epub 2021 Oct 13.

Neurology Department, Mayo Hospital, Lahore, Pakistan.

Autonomic dysfunction in Guillain-Barrè syndrome (GBS) involves labile hypotension, hypertension, resting tachycardia and sweating. While autonomic involvement affects 66% of patients with GBS, the changes are usually transient and reversible. We hereby delineate a case of a female who presented to our medical centre with flaccid, painless progressive quadriparesis with features of dysautonomia. Read More

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October 2021