J Biol Chem 2021 Mar 10:100533. Epub 2021 Mar 10.
MRC Laboratory Molecular Cell Biology, University College London, Gower Street, WC1E 6BT, London, UK; UCL Cancer Institute, University College London, Gower Street, WC1E 6BT, London, UK. Electronic address:
Saccharomyces cerevisiae exhibits gene expression homeostasis, which is defined as the buffering of transcription levels against changes in DNA copy number during the S phase of the cell cycle. It has been suggested that S. cerevisiae employs an active mechanism to maintain gene expression homeostasis through Rtt109-Asf1-dependent acetylation of histone H3 on lysine 56 (H3K56). Read More