Radiol Imaging Cancer 2020 Nov 27;2(6):e200033. Epub 2020 Nov 27.
Department of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Purpose: To determine whether MR spectroscopic assessment of fine-needle aspiration (FNA) biopsy specimens from suspicious breast lesions could be used to improve the diagnostic utility of FNA biopsies for the characterization of breast lesions.
Materials And Methods: In this prospective study, a previously reported technique using high-spatial-resolution proton MR spectroscopy was modified and used to examine the utility of FNA biopsies in the evaluation of suspicious breast lesions. Tissue samples from 115 lesions (from 102 women; average age, 54 years) were excised by using FNA and core biopsies and were collected between September 7, 2012, and April 11, 2014. Read More