17,642 results match your criteria hispanics african


Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.

Hum Mol Genet 2021 Jun 24. Epub 2021 Jun 24.

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, 91101, USA.

Central obesity is a leading health concern with a great burden carried by ethnic minority populations, especially Hispanics/Latinos. Genetic factors contribute to the obesity burden overall and to inter-population differences. We aimed to identify loci associated with central adiposity measured as waist-to-hip ratio (WHR), waist circumference (WC), and hip circumference (HIP) adjusted for body mass index (adjBMI), using the Hispanic Community Health Study/Study of Latinos (HCHS/SOL); determine if differences in associations differ by background group within HCHS/SOL; and determine whether previously reported associations generalize to HCHS/SOL. Read More

View Article and Full-Text PDF

Long-term air pollution and other risk factors associated with COVID-19 at the census tract level in Colorado.

Environ Pollut 2021 Jun 14;287:117584. Epub 2021 Jun 14.

Colorado Department of Public Health and Environment, United States.

Previous nationwide studies have reported links between long-term concentrations of fine particulate matter (PM2.5) and COVID-19 infection and mortality rates. In order to translate these results to the state level, we use Bayesian hierarchical models to explore potential links between long-term PM2. Read More

View Article and Full-Text PDF

Bias Issues in Colorectal Cancer Management: A Review.

Ann Surg Oncol 2021 Jun 17. Epub 2021 Jun 17.

Department of Surgery, The University of Illinois at Chicago, Chicago, IL, USA.

Based on census data, over one-third of the US population identifies as a racial or ethnic minority. This group of racial and ethnic minorities is more likely to develop cancer and die from it when compared with the general population of the USA. These disparities are most pronounced in the African American community. Read More

View Article and Full-Text PDF

Common genetic variation in circadian clock genes are associated with cardiovascular risk factors in an African American and Hispanic/Latino cohort.

Int J Cardiol Heart Vasc 2021 Jun 3;34:100808. Epub 2021 Jun 3.

Department of Medicine, Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.

Misalignment of the internal circadian time with external physical time due to environmental factors or due to genetic variantion in circadian clock genes has been associated with increased incidence of cardiovascular risk factors. Common genetic variation in circadian genes in the United States have been identified predominantly in European ancestry individuals. We therefore examined the association between circadian clock single nucleotide polymorphisms (SNPs) in genes and cardiovascular risk factors in African Americans and Hispanic/Latinos. Read More

View Article and Full-Text PDF

Twitter discourse reveals geographical and temporal variation in concerns about COVID-19 vaccines in the United States.

Vaccine 2021 Jun 9. Epub 2021 Jun 9.

Penn Medicine Center for Digital Health, University of Pennsylvania, Philadelphia, PA, United States; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Leondard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia PA, United States.

The speed at which social media is propagating COVID-19 misinformation and its potential reach and impact is growing, yet little work has focused on the potential applications of these data for informing public health communication about COVID-19 vaccines. We used Twitter to access a random sample of over 78 million vaccine-related tweets posted between December 1, 2020 and February 28, 2021 to describe the geographical and temporal variation in COVID-19 vaccine discourse. Urban suburbs posted about equitable distribution in communities, college towns talked about in-clinic vaccinations near universities, evangelical hubs posted about operation warp speed and thanking God, exurbs posted about the 2020 election, Hispanic centers posted about concerns around food and water, and counties in the ACP African American South posted about issues of trust, hesitancy, and history. Read More

View Article and Full-Text PDF

The association of California's Proposition 56 tobacco tax increase with smoking behavior across racial and ethnic groups and by income.

Nicotine Tob Res 2021 Jun 17. Epub 2021 Jun 17.

Institute for Health & Aging, School of Nursing, University of California, San Francisco, CA.

Introduction: On April 1, 2017, California Proposition 56 (Prop 56) was implemented, increasing the excise tax on cigarettes by $2/pack. This study compares the association of Prop 56 with smoking prevalence and smoking intensity across racial/ethnic groups, further examining distinctions across income subgroups within each racial/ethnic group.

Methods: The study used pooled cross-sectional data from the 2012-2018 California Behavioral Risk Factor Surveillance System. Read More

View Article and Full-Text PDF

Can Innovative Technologies Overcome HbA1c Disparity for African-American Youth with Type 1 Diabetes?

J Diabetes Sci Technol 2021 Jun 17:19322968211021386. Epub 2021 Jun 17.

Endocrinology and Diabetes, The Children's Hospital of New Orleans, New Orleans, LA, USA.

Achieving normal or near-normal glycemic control as reflected by HbA1c levels in patients with type 1 diabetes (T1D) is important for preventing the development and progression of chronic complications. Despite delineation and dissemination of HbA1c management targets and advances in insulin pharmacology, insulin delivery systems, and glucose monitoring, the majority of children with T1D do not achieve HbA1c goals. In particular, African Americans are more likely not to reach HbA1c goals and have persistently higher HbA1c than Non-Hispanic Whites. Read More

View Article and Full-Text PDF

Determinants of Lung Fissure Completeness.

Am J Respir Crit Care Med 2021 Jun 14. Epub 2021 Jun 14.

University Medical Center Groningen, Pulmonary diseases, Groningen, Netherlands.

Rationale: New advanced bronchoscopic treatment options for patients with severe COPD have led to increased interest for COPD phenotyping, including fissure completeness.

Objectives: We investigated clinical, environmental, and genetic factors contributing to fissure completeness in patients with and without COPD.

Methods: We used data of 9926 participants of the COPDGene study who underwent chest computed tomography (CT). Read More

View Article and Full-Text PDF

Temporal transition of racial/ethnic disparities in COVID-19 outcomes in 3108 counties of the United States: Three phases from January to December 2020.

Sci Total Environ 2021 Jun 1;791:148167. Epub 2021 Jun 1.

School of the Environment, Yale University, New Haven, CT, United States of America.

Early studies reported higher risk of COVID-19 outcomes for racial/ethnic minorities in the early phase of the pandemic in the United States. While the initial surge of COVID-19 was concentrated in some areas, COVID-19 became pervasive across the entire continent with high impacts in the northern region and central region in the end of 2020. With this geographical transition, we aim to investigate patterns of these racial/ethnic disparities over time. Read More

View Article and Full-Text PDF

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.

BMC Genomics 2021 Jun 9;22(1):432. Epub 2021 Jun 9.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Background: Circulating white blood cell and platelet traits are clinically linked to various disease outcomes and differ across individuals and ancestry groups. Genetic factors play an important role in determining these traits and many loci have been identified. However, most of these findings were identified in populations of European ancestry (EA), with African Americans (AA), Hispanics/Latinos (HL), and other races/ethnicities being severely underrepresented. Read More

View Article and Full-Text PDF

Impact of alcohol use disorder on stroke risk in geriatric patients with prediabetes: A nationwide analysis.

Int J Clin Pract 2021 Jun 9:e14477. Epub 2021 Jun 9.

Division of Cardiology, Atlanta VA Medical Center, Decatur, GA, USA.

Background: With rising trends of prediabetes in the geriatric population, we aim to assess the impact of alcohol use disorder (AUD) on the outcomes of patients with prediabetes.

Methods: Hospitalisations amongst the patients (≥65 years) with prediabetes were identified with a diagnosis of AUD and in-hospital stroke using the National Inpatient Sample database (2007-2014). We compared demographics, comorbidities, all-cause mortality, stroke rate and resource utilisation in the elderly prediabetes patients with vs without AUD. Read More

View Article and Full-Text PDF

COVID-19 among Minority Children in Detroit, Michigan during the Early National Surge of the Pandemic.

Glob Pediatr Health 2021 31;8:2333794X211022710. Epub 2021 May 31.

Children's Hospital of Michigan, Detroit, MI, USA.

. The COVID-19 pandemic has shed light on communities of racial/ethnic minority groups in the US where long-standing health issues and structural inequities are now known to have resulted in increased risk for infection, severe illness, and death from the virus. The objective of our study was to describe demographic characteristics, clinical presentations, medical interventions and outcomes of pediatric patients with COVID-19 treated at Children's Hospital of Michigan (CHM), a tertiary care center in urban Detroit, an early hotspot during the initial surge of the SARS-CoV-2 pandemic. Read More

View Article and Full-Text PDF

A retrospective cohort study of race/ethnicity, pre-pregnancy weight, and pregnancy complications.

J Matern Fetal Neonatal Med 2021 Jun 8:1-8. Epub 2021 Jun 8.

Department of Health Services, School of Public Health, University of Washington, Seattle, WA, USA.

Objective: To examine the relationship between race/ethnicity, pre-pregnancy overweight/obesity status, and pregnancy complications.

Methods: We conducted a retrospective cohort study among mothers with singleton live births using data from hospitals contributing to the Obstetrical Care Outcomes Assessment Program database ( = 72,697). Race was categorized as Non-Hispanic (NH) White, NH African-American, Hispanic, NH Asian, NH American Indian/Alaskan Native, and NH Native-Hawaiian/Other Pacific Islander. Read More

View Article and Full-Text PDF

Mitochondrial DNA haplogroups and domain-specific neurocognitive performance in adults with HIV.

J Neurovirol 2021 Jun 8. Epub 2021 Jun 8.

Vanderbilt University Medical Center, Nashville, TN, USA.

Neurocognitive (NC) impairment (NCI) is an important cause of morbidity in persons with HIV (PWH). In the high-energy environment of the central nervous system, mitochondria contribute to neuroinflammation and aging, which may ultimately drive the pathogenesis of neurodegenerative diseases. Mitochondrial DNA (mtDNA) haplogroups are associated with health outcomes in PWH. Read More

View Article and Full-Text PDF

Associations of Race/Ethnicity and Food Insecurity With COVID-19 Infection Rates Across US Counties.

JAMA Netw Open 2021 06 1;4(6):e2112852. Epub 2021 Jun 1.

College of Agricultural Sciences, Pennsylvania State University, University Park.

Importance: Food insecurity is prevalent among racial/ethnic minority populations in the US. To date, few studies have examined the association between pre-COVID-19 experiences of food insecurity and COVID-19 infection rates through a race/ethnicity lens.

Objective: To examine the associations of race/ethnicity and past experiences of food insecurity with COVID-19 infection rates and the interactions of race/ethnicity and food insecurity, while controlling for demographic, socioeconomic, risk exposure, and geographic confounders. Read More

View Article and Full-Text PDF

Rural-Urban Disparity in Mortality in the US From 1999 to 2019.

JAMA 2021 Jun;325(22):2312-2314

Department of Medicine, VA Boston Healthcare System, Boston, Massachusetts.

View Article and Full-Text PDF

Association of Lower Socioeconomic Status and SARS-CoV-2 Positivity in Los Angeles, California.

J Prev Med Public Health 2021 May 13;54(3):161-165. Epub 2021 Apr 13.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads heterogeneously, disproportionately impacting poor and minority communities. The relationship between poverty and race is complex, with a diverse set of structural and systemic factors driving higher rates of poverty among minority populations. The factors that specifically contribute to the disproportionate rates of SARS-CoV-2 infection, however, are not clearly understood. Read More

View Article and Full-Text PDF

Changes in cannabis, tobacco, and alcohol use among sexually active female adolescents and young adults over a twelve-year period ending in 2019.

Addict Behav 2021 10 24;121:106994. Epub 2021 May 24.

Department of Cancer Prevention & Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

Background: The United States has experienced an increasing divergence in cannabis, tobacco, and alcohol use among adolescents and young adults (AYA). We assessed the changes in cannabis, tobacco and alcohol use in an inner-city population of predominantly minority AYA females attending a large adolescent-specific health center in New York City.

Methods: This was a longitudinal study of AYA women recruited and followed over a twelve-year period between 2007 and 2019. Read More

View Article and Full-Text PDF
October 2021

Racial and Ethnic Disparities in Access to Local Anesthesia for Inguinal Hernia Repair.

J Surg Res 2021 Jun 1;266:366-372. Epub 2021 Jun 1.

Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas; North Texas VA Healthcare System, Dallas, Texas; University of Texas Southwestern Surgical Center for Outcomes, Implementation, and Novel Interventions (S-COIN), Dallas, Texas.

Background: Many studies have identified racial disparities in healthcare, but few have described disparities in the use of anesthesia modalities. We examined racial disparities in the use of local versus general anesthesia for inguinal hernia repair. We hypothesized that African American and Hispanic patients would be less likely than Caucasians to receive local anesthesia for inguinal hernia repair. Read More

View Article and Full-Text PDF

Addressing Racial and Ethnic Disparities in COVID-19 Among School-Aged Children: Are We Doing Enough?

Prev Chronic Dis 2021 06 3;18:E55. Epub 2021 Jun 3.

Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

The disproportionate impact of COVID-19 and associated disparities among Hispanic, non-Hispanic Black, and non-Hispanic American Indian/Alaska Native children and teenagers has been documented. Reducing these disparities along with overcoming unintended negative consequences of the pandemic, such as the disruption of in-person schooling, calls for broad community-based collaborations and nuanced approaches. Based on national survey data, children from some racial and ethnic minority groups have a higher prevalence of obesity, asthma, type 2 diabetes, and hypertension; were diagnosed more frequently with COVID-19; and had more severe outcomes compared with their non-Hispanic White (NHW) counterparts. Read More

View Article and Full-Text PDF

Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials.

Breast Cancer Res Treat 2021 Jun 2;187(3):605-611. Epub 2021 Jun 2.

Department of Biology, Georgia State University, 100 Piedmont Ave, Atlanta, GA, 30303, USA.

Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity. Read More

View Article and Full-Text PDF

Factors Associated with Viral Suppression among Racial/Ethnic Minority Women in the Miami-Dade County Ryan White Program, 2017.

AIDS Res Hum Retroviruses 2021 Jun 3. Epub 2021 Jun 3.

Florida International University, 5450, 11200 SW 8th St, Miami, Florida, United States, 33199-2156;

Background: The study's objective was to identify factors associated with differences in the rate of viral suppression among minority women with HIV/AIDS in care in the Miami-Dade County Ryan White Program (RWP).

Methods: A retrospective cohort study was conducted using social characteristics and laboratory data of minority women enrolled in the Miami-Dade County RWP in 2017. Viral suppression was defined as <200 copies/ml using the last viral load test of 2017. Read More

View Article and Full-Text PDF

Structural Racism and the COVID-19 Experience in the United States.

Health Secur 2021 Jun 1;19(S1):S14-S26. Epub 2021 Jun 1.

Katherine L. Dickinson, PhD, is an Assistant Professor and Natalie Banacos, MS, is a Professional Research Assistant; both in the Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Anschutz, Aurora, CO. Jennifer D. Roberts, DrPH, is an Assistant Professor, Department of Kinesiology, School of Public Health, University of Maryland, College Park, MD. Lindsay Neuberger, PhD, is an Associate Professor, Nicholson School of Communication and Media, University of Central Florida, Orlando, FL. Elizabeth Koebele, PhD, is an Assistant Professor, Department of Political Science, University of Nevada, Reno, Reno, NV. Danielle Blanch-Hartigan, PhD, MPH, is Associate Professor of Health Studies, Department of Natural and Applied Sciences, Bentley University, Waltham, MA. Elizabeth A. Shanahan, DA, MPA, MS, is a Professor and Associate Vice President of Research Development, Department of Political Science, Montana State University, Bozeman, MT.

The long, fallacious history of attributing racial disparities in public health outcomes to biological inferiority or poor decision making persists in contemporary conversations about the COVID-19 pandemic. Given the disproportionate impacts of this pandemic on communities of color, it is essential for scholars, practitioners, and policymakers to focus on how structural racism drives these disparate outcomes. In May and June 2020, we conducted a 6-state online survey to examine racial/ethnic differences in exposure to COVID-19, risk mitigation behaviors, risk perceptions, and COVID-19 impacts. Read More

View Article and Full-Text PDF

Factors Associated with Influenza Vaccination Uptake among U.S. Adults: Focus on Nativity and Race/Ethnicity.

Int J Environ Res Public Health 2021 05 17;18(10). Epub 2021 May 17.

College of Nursing and Research Institute of Nursing Science, Seoul National University, Seoul 03080, Korea.

To support implementation strategies for upcoming influenza (flu) vaccinations for foreign-born and racial/ethnic minority groups, we analyzed the 2018 National Health Interview Survey (NHIS) database and performed logistic regression to examine the factors associated with, and the interaction between nativity and race/ethnicity in directing flu vaccination rates during the past 12 months ( = 25,045). As a result, we found nativity and race/ethnicity were associated with flu vaccination rates; foreign-born and non-Hispanic black respondents were less likely to take the vaccine than U.S. Read More

View Article and Full-Text PDF

Long-term depression incidence and associated mortality among African American and White prostate cancer survivors.

Cancer 2021 Jun 1. Epub 2021 Jun 1.

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.

Background: Depression is common after a diagnosis of prostate cancer and may contribute to poor outcomes, particularly among African Americans. The authors assessed the incidence and management of depression and its impact on overall mortality among African American and White veterans with localized prostate cancer.

Methods: The authors used the Veterans Health Administration Corporate Data Warehouse to identify 40,412 African American and non-Hispanic White men diagnosed with localized prostate cancer from 2001 to 2013. Read More

View Article and Full-Text PDF

New Drug Formulary Management and Utilization: Evidence in Sex, Race, and Ethnicity: 2019-2020.

Ann Pharmacother 2021 May 28:10600280211019765. Epub 2021 May 28.

Clinical Pharmacy Associates, Laurel, MD, USA.

Background: It is well established that females and persons of racial and ethnic minorities are frequently underrepresented in clinical trials. These disparities are potentially important aspects of evidence-based formulary management and drug utilization review (DUR) processes.

Objective: The purpose of this study was to review the demographic composition of pivotal trials and post-approval study requirements for recent FDA-approved drugs, analyzing the representation of minority groups and its generalizability to the US population or corresponding disease state. Read More

View Article and Full-Text PDF

Race and ethnicity representation in clinical trials: findings from a literature review of Phase I oncology trials.

Future Oncol 2021 May 28. Epub 2021 May 28.

University of Iowa, Holden Comprehensive Cancer Center, Iowa City, IA 52242, USA.

To provide an assessment of published literature on the demographic representation in Phase I trials of biopharmaceutical oncology agents. We conducted a rapid evidence assessment to identify demographic representation reported in Phase I clinical trials for biopharmaceutical oncology agents published in 2019. Globally, the population was predominantly White/Caucasian (62. Read More

View Article and Full-Text PDF

Barriers for Ethnic Minorities and Low Socioeconomic Status Pediatric Patients for Behavioral Health Services and Benefits of an Integrated Behavioral Health Model.

Pediatr Clin North Am 2021 Jun;68(3):651-658

Department of Neurology, University of Minnesota Medical Center, 516 Delaware Street, SE 12-100 Phillips Wangensteen Building, Minneapolis, MN 55455, USA.

The integrated behavioral health care model in primary care has the potential to reduce barriers to care experienced by children and families from ethnic minorities and low socioeconomic status. Limited access to pediatric behavioral health care is a significant problem, with up to 40% of children and adolescents with identified mental disorders and only 30% of them receiving care. Barriers include transportation, insurance, and shortage of specialists. Read More

View Article and Full-Text PDF

Factors Associated With Racial/Ethnic Group-Based Medical Mistrust and Perspectives on COVID-19 Vaccine Trial Participation and Vaccine Uptake in the US.

JAMA Netw Open 2021 05 3;4(5):e2111629. Epub 2021 May 3.

Faith-Based Genetic Research Institute, Detroit, Michigan.

Importance: The impact of COVID-19 in the US has been far-reaching and devastating, especially in Black populations. Vaccination is a critical part of controlling community spread, but vaccine acceptance has varied, with some research reporting that Black individuals in the US are less willing to be vaccinated than other racial/ethnic groups. Medical mistrust informed by experiences of racism may be associated with this lower willingness. Read More

View Article and Full-Text PDF

Understanding Risk Factors for Poor Outcomes in a Multiethnic Longitudinal Cohort: The LUMINA (Lupus in Minorities: Nature vs. Nurture) Experience (LUMINA LXXXII).

Rheum Dis Clin North Am 2021 Feb 29;47(1):55-64. Epub 2020 Oct 29.

Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham, USA; Department of Medicine, School of Medicine, Universidad Peruana Cayetano Heredia. Lima, Perú. Electronic address:

The Lupus in Minorities: Nature Vs Nurture (LUMINA) cohort has placed Hispanics on the lupus map in the United States. Texan Hispanic and African American patients experience, overall, worse outcomes than the Caucasian and Puerto Rican Hispanic patients. The genetic component of ethnicity is important early in the disease course whereas socioeconomic factors become more important subsequently. Read More

View Article and Full-Text PDF
February 2021