5,668 results match your criteria highest deviation

Examination of How Well Long-Range-Corrected Density Functionals Satisfy the Ionization Energy Theorem.

J Chem Theory Comput 2021 Jul 28. Epub 2021 Jul 28.

Department of Chemistry, Chemical Theory Center, and Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, Minnesota 55455-0431, United States.

We calculated the vertical ionization energies (VIE) of 99 species in two ways to examine the accuracy of several long-range-corrected (LC) hybrid meta functionals in comparison with a gradient approximation (GA), global hybrids, and doubly hybrids. In the category of LC functionals, we examined both those with meta ingredients (i.e. Read More

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Pioglitazone use associated with reduced risk of the first attack of ischemic stroke in patients with newly onset type 2 diabetes: a nationwide nested case-control study.

Cardiovasc Diabetol 2021 Jul 27;20(1):152. Epub 2021 Jul 27.

Department of Psychiatry, Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Background: Pioglitazone use is known to be associated with a reduced risk of recurrent stroke in patients with diabetes mellitus (DM) who have a history of stroke. However, it is unclear whether this benefit extends to patients without a history of stroke. We aimed to evaluate the association between pioglitazone use and development of first attack of ischemic stroke in patients with newly diagnosed type 2 DM. Read More

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Extracellular volume-guided late gadolinium enhancement analysis for non-ischemic cardiomyopathy: The Women's Interagency HIV Study.

BMC Med Imaging 2021 Jul 27;21(1):116. Epub 2021 Jul 27.

Division of Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe Street MR 110, Baltimore, MD, 21287, USA.

Background: Quantification of non-ischemic myocardial scar remains a challenge due to the patchy diffuse nature of fibrosis. Extracellular volume (ECV) to guide late gadolinium enhancement (LGE) analysis may achieve a robust scar assessment.

Methods: Three cohorts of 80 non-ischemic-training, 20 non-ischemic-validation, and 10 ischemic-validation were prospectively enrolled and underwent 3. Read More

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Impact of four kVp combinations available in a dual-source CT on the spectral performance of abdominal imaging: A task-based image quality assessment on phantom data.

J Appl Clin Med Phys 2021 Jul 26. Epub 2021 Jul 26.

Department of medical imaging, Nîmes Medical Imaging Group, CHU Nimes, Univ Montpellier, Nimes, France.

Purpose: To compare the spectral performance of four combinations of kVp available in a third generation dual-source CT (DSCT) on abdominal imaging.

Methods: An image-quality phantom was scanned with a DSCT using four kVp pairs (tube "A" voltage/tube "B" voltage): 100/Sn150 kVp, 90/Sn150 kVp, 80/Sn150 kVp, and 70/Sn150 kVp, classic parameters and dose level for abdomen examination (CTDI : 11 mGy). The noise power spectrum (NPS) and the task-based transfer function (TTF) of two inserts were computed on virtual monochromatic images (VMIs) at 40/50/60/70 keV and for mixed, low-, and high-kVp images. Read More

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Age patterns in overweight and wasting prevalence of under 5-year-old children from low- and middle-income countries.

Int J Obes (Lond) 2021 Jul 22. Epub 2021 Jul 22.

International Center for Equity in Health, Federal University of Pelotas, Pelotas, Brazil.

Objectives: To describe how overweight and wasting prevalence varies with age among children under 5 years in low- and middle-income countries (LMICs).

Methods: We used data from nationally representative Demographic and Health Surveys and Multiple Indicator Cluster Surveys. Overweight and wasting prevalence were defined as the proportions of children presenting mean weight for length/height (WHZ) more than 2 standard deviations above or below 2 standard deviations from the median value of the 2006 WHO standards, respectively. Read More

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Effect of internal design changes on the mechanical properties of laser-sintered cobalt-chromium specimens.

J Prosthet Dent 2021 Jul 19. Epub 2021 Jul 19.

Professor, Cukurova University, Faculty of Dentistry, Department of Prosthodontics, Adana, Turkey.

Statement Of Problem: Changing the internal design of a metal framework may decrease the manufacturing time, the weight of the restoration, and the amount of alloy powder used, as well as simplify the fabrication process.

Purpose: The purpose of this in vitro study was to evaluate the effect of framework internal design changes on the mechanical properties of cobalt-chromium (Co-Cr) specimens manufactured by using direct metal laser sintering (DMLS).

Material And Methods: Dumbbell-shaped test specimens were designed as per the International Organization for Standardization (ISO) 22674(E) standard by using a 3-dimensional software program. Read More

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Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry.

Mitochondrion 2021 Jul 21. Epub 2021 Jul 21.

Framingham Heart Study, Framingham, MA 01702, USA; Population Sciences Branch, NHLBI/NIH, Bethesda, MD 20892, USA.

We investigated the concordance of mitochondrial DNA heteroplasmic mutations (heteroplasmies) in 6,745 maternal pairs of European (EA, n=4,718 pairs) and African (AA, n=2,027 pairs) Americans in whole blood. Mother-offspring pairs displayed the highest concordance rate, followed by sibling-sibling and more distantly-related maternal pairs. The allele fractions of concordant heteroplasmies exhibited high correlation (R=0. Read More

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Wide-field optical coherence tomography deviation map for early glaucoma detection.

Br J Ophthalmol 2021 Jul 22. Epub 2021 Jul 22.

Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of Korea

Background/aims: This study aimed to establish a wide-field optical coherence tomography (OCT) deviation map obtained from swept-source OCT (SS-OCT) scans. Moreover, it also aimed to compare the diagnostic ability of this wide-field deviation map with that of the peripapillary and macular deviation maps currently being used for the detection of early glaucoma (EG).

Methods: Four hundred eyes, including 200 healthy eyes and 200 eyes with EG were enrolled in this retrospective observational study. Read More

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3D Modelling of Mass Transfer into Bio-Composite.

Polymers (Basel) 2021 Jul 9;13(14). Epub 2021 Jul 9.

IATE, Univ Montpellier, CIRAD, INRAE, Institut Agro, 34060 Montpellier, France.

A three-dimensional model structure that allows considering interphase layer around permeable inclusions is developed to predict water vapor permeability in composite materials made of a matrix Poly(3-HydroxyButyrate--3-HydroxyValerate) (PHBV) including Wheat Straw Fiber (WSF) particles. About 500 two-phase structures corresponding to composites of different particles volume fractions (5.14-11. Read More

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Body Mass Index and Dental Caries, a Five-Year Follow-Up Study in Mexican Children.

Int J Environ Res Public Health 2021 Jul 11;18(14). Epub 2021 Jul 11.

Laboratorio de Microbiología, Posgrado de la Facultad de Odontología, Universidad Nacional Autónoma de México, Ciudad de México 04360, Mexico.

There are conflicting reports on a possible association between body mass index (BMI) and caries. Given the ongoing worldwide increase in obesity, we undertook a 5-year follow-up study on 201 Mexican schoolchildren to analyse their BMI and dental caries experience. The children's weight and height were recorded, and their BMI was calculated using the WHO tables. Read More

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Triglyceride-Glukose Index Predicts Adverse Events in Patients with Acute Coronary Syndrome: A Meta-Analysis of Cohort Studies.

Horm Metab Res 2021 Jul 23. Epub 2021 Jul 23.

Department of Cardiovascular Medicine, The First People's Hospital of Yibin City, Yibin, China.

The triglyceride-glucose (TyG) index, a recently proposed indicator for insulin resistance, has been related with cardiovascular risks. We aimed to summarize the association between TyG index and incidence of major adverse cardiovascular events (MACEs) in patients with acute coronary syndrome (ACS). Cohort studies demonstrating the association between TyG index and incidence of MACEs in ACS patients with multivariate adjusted analyses were identified by search of PubMed, Embase, and Web of Science databases. Read More

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Provider attitudes and satisfaction with rapid preoperative point-of-care COVID-19 testing using ID NOW™.

Can J Anaesth 2021 Jul 22. Epub 2021 Jul 22.

Department of Anesthesia and Perioperative Medicine, Royal Columbian Hospital, 330 E Columbia St, New Westminster, BC, V3L 3W7, Canada.

Purpose: Healthcare workers have experienced high levels of anxiety during the COVID-19 pandemic, particularly when caring for patients with unknown infection status. We trialled rapid preoperative point-of-care COVID-19 testing using the Abbott ID NOW™ COVID-19 for clinical validation in an urgent surgical population at a single centre in British Columbia, Canada. Here, we sought to determine the opinions and beliefs of operating room (OR) staff on the usefulness and effectiveness of point-of-care tests on workflow and wellbeing in the OR. Read More

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Clinical presentation of inguinal hernia among adults in Uyo, Nigeria.

I A Udo

Niger J Clin Pract 2021 Jul;24(7):1082-1085

Department of Surgery, University of Uyo/University of Uyo Teaching Hospital, Uyo, Nigeria.

Background: Inguinal hernia is a common pathology seen by the general surgeon in the outpatient clinic. Its spectrum of clinical features on presentation significantly varies from the asymptomatic to the complicated.

Objective: To identify and audit the common clinical presentation and presence of known risk factors for inguinal hernia among adult patients with inguinal hernias presenting to an outpatient clinic. Read More

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CBCT image artefacts generated by implants located inside the field of view or in the exomass.

Dentomaxillofac Radiol 2021 Jul 21:20210092. Epub 2021 Jul 21.

Division of Oral Radiology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.

Objectives: To compare artefacts in cone-beam computed tomography (CBCT) arising from implants of different materials located either inside the field-of-view (FOV) or in the exomass, and to test different image-acquisition parameters to reduce them.

Methods: CBCT scans of a human mandible prepared with either a titanium, titanium-zirconium, or zirconia implant were acquired with the Planmeca ProMax utilizing FOV sizes of 8 × 5 cm and 4 × 5 cm, which placed the implant inside the FOV (8 × 5 cm) or in the exomass (4 × 5 cm). The scanning parameters considered three conditions of metal artefact reduction (MAR), disabled, low, and high, and two kVp levels (80 and 90). Read More

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Simple benchmarking method for determining the accuracy of depth cameras in body landmark location estimation: Static upright posture as a measurement example.

PLoS One 2021 21;16(7):e0254814. Epub 2021 Jul 21.

Human Augmentation Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.

To evaluate the postures in ergonomics applications, studies have proposed the use of low-cost, marker-less, and portable depth camera-based motion tracking systems (DCMTSs) as a potential alternative to conventional marker-based motion tracking systems (MMTSs). However, a simple but systematic method for examining the estimation errors of various DCMTSs is lacking. This paper proposes a benchmarking method for assessing the estimation accuracy of depth cameras for full-body landmark location estimation. Read More

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Impact of home blood pressure variability on cardiovascular outcome in patients with arterial stiffness: Results of the J-HOP study.

J Clin Hypertens (Greenwich) 2021 Jul 20. Epub 2021 Jul 20.

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan.

This study sought to investigate whether the relation between increased blood pressure (BP) variability and increased arterial stiffness confers a risk for cardiovascular disease (CVD) events. We analyzed 2648 patients from a practitioner-based population (mean ± SD age 64.9 ± 11. Read More

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Combined effect of visit-to-visit variations in heart rate and systolic blood pressure on all-cause mortality in hypertensive patients.

Hypertens Res 2021 Jul 20. Epub 2021 Jul 20.

Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China.

Elevated resting heart rate (RHR) and systolic blood pressure (SBP) are independent risk factors for all-cause mortality in hypertensive patients. However, the association of the visit-to-visit variation (VVV) in SBP and RHR with the risk of mortality in hypertensive patients remains unknown. The aim of this study was to investigate the effects of the VVVs in SBP and RHR on the risk of all-cause mortality. Read More

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Frequency of Visit-to-Visit Variability of Resting Heart Rate and the Risk of New-Onset Atrial Fibrillation in the General Population.

Am J Cardiol 2021 Jul 17. Epub 2021 Jul 17.

Department of Cardiology, Chinese PLA General Hospital, Beijing, China. Electronic address:

Resting heart rate (RHR) has been an established predictor for atrial fibrillation (AF). However, the association of visit-to-visit heart rate variability (VVHRV) with new-onset AF risk over long term remains unclear. Our study investigates the relation of VVHRV to new-onset AF in general population in the prospective study of the Kailuan cohort. Read More

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Identifying Communities at Risk for COVID-19-Related Burden Across 500 U.S. Cities and within New York City: Unsupervised Learning of Co-Prevalence of Health Indicators.

JMIR Public Health Surveill 2021 Jul 15. Epub 2021 Jul 15.

XY.ai, 56 JFK Street, Cambridge, US.

Background: While it is well-known that older individuals with certain comorbidities are at highest risk for complications related to COVID-19 including hospitalization and death, we lack tools to identify communities at highest risk with fine-grained spatial resolution. Information collected at a county level obscures local risk and complex interactions between clinical comorbidities, the built environment, population factors, and other social determinants of health.

Objective: Development of a COVID-19 Community Risk Score that summarizes complex disease prevalence together with age and sex, and compare the score to different social determinants of health indicators and built environment measures derived from satellite images using deep-learning. Read More

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Influence of agricultural activities on atmospheric pollution during post-monsoon harvesting seasons at a rural location of Indo-Gangetic Plain.

Sci Total Environ 2021 Jul 7;796:148903. Epub 2021 Jul 7.

Department of Environment Studies, Panjab University, Chandigarh 160014, India. Electronic address:

The emissions from agricultural activities significantly impact the air quality at local (rural) and regional scales. The study monitored the near real-time concentrations of emission from agrarian activities, i.e. Read More

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A catalog of validity indices for step counting wearable technologies during treadmill walking: the CADENCE-Kids study.

Int J Behav Nutr Phys Act 2021 07 16;18(1):97. Epub 2021 Jul 16.

College of Health and Human Services, University of North Carolina at Charlotte, 9201 University City Blvd., Charlotte, NC, 28223, USA.

Background: Wearable technologies play an important role in measuring physical activity (PA) and promoting health. Standardized validation indices (i.e. Read More

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Hyperpolarized Xe magnetic resonance imaging for functional avoidance treatment planning in thoracic radiation therapy: a comparison of ventilation- and gas-exchange-guided treatment plans.

Int J Radiat Oncol Biol Phys 2021 Jul 12. Epub 2021 Jul 12.

Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC, USA.

Purpose: To present a methodology to use pulmonary gas exchange maps to guide functional avoidance treatment planning in radiation therapy (RT), and evaluate its efficacy compared to ventilation-guided treatment planning.

Methods: Prior to receiving conventional RT for non-small cell lung cancer, eleven patients underwent hyperpolarized Xe gas exchange magnetic resonance imaging (MRI) to map the distribution of xenon in its gas phase (ventilation) and transiently bound to red blood cells in the alveolar capillaries (gas exchange). Both ventilation and gas exchange maps were independently used to guide development of new functional avoidance treatment plans for every patient, while adhering to institutional dose-volume constraints for normal tissues and target coverage. Read More

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Assessment of trace levels of aflatoxins AFB1 and AFB2 in non-dairy beverages by molecularly imprinted polymer based micro solid-phase extraction and liquid chromatography-tandem mass spectrometry.

Anal Methods 2021 Jul 14. Epub 2021 Jul 14.

Trace Element, Spectroscopy and Speciation Group (GETEE), Strategic Grouping in Materials (AEMAT), Department of Analytical Chemistry, Nutrition and Bromatology, Faculty of Chemistry, Universidade de Santiago de Compostela, Avenida das Ciencias, s/n, 15782-Santiago de Compostela, Spain.

A selective molecularly imprinted polymer (MIP) adsorbent was synthesised and used in a batch micro-solid phase extraction format for isolating aflatoxins (AFB1, and AFB2) from non-dairy beverages before liquid chromatography-tandem mass spectrometry determination. MIP synthesis (precipitation polymerization in 3 : 1 acetonitrile/toluene as a porogen) was performed with 5,7-dimethoxycoumarin (DMC), methacrylic acid (MAA) and divinylbenzene-80 (DVB) as a dummy template, functional monomer and cross-linker, respectively (1 : 4 : 20 molar ratio). 2,2'-Azobisisobutyronitrile (AIBN) was used as a polymerization initiator. Read More

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Relationship Between Protein Intake and Sarcopenia in the Elderly with Nonalcoholic Fatty Liver Disease Based on the Fourth and Fifth Korea National Health and Nutrition Examination Survey.

Metab Syndr Relat Disord 2021 Jul 13. Epub 2021 Jul 13.

Department of Human Ecology, Graduate School, Korea University, Seoul, Korea.

The association between sarcopenia and protein intake has been well studied. However, limited data are available on the association between sarcopenia and protein intake in people with nonalcoholic fatty liver disease (NAFLD). This study aimed to investigate the association between protein intake and sarcopenia among elderly participants with NAFLD using the Korea National Health and Nutrition Examination Survey (KNHANES). Read More

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Firearm licenses associated with elevated pediatric blood lead levels in Massachusetts.

Environ Res 2021 Jul 9;202:111642. Epub 2021 Jul 9.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Objective: To determine the association between firearm-related lead exposure and pediatric blood lead levels.

Methods: Using data available through the Massachusetts Departments of Public Health and Criminal Justice Information Services, we examined the association between active class A firearm licenses in a community with the prevalence of elevated blood lead levels in children aged 0-4. Correlational and hierarchical multiple regression analyses were conducted with potential confounders and other exposures such as lead paint, lead in water, presence of firing ranges, and social, economic, and occupational variables. Read More

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Association Between Visceral Fat and Brain Cortical Thickness in the Elderly: A Neuroimaging Study.

Front Aging Neurosci 2021 23;13:694629. Epub 2021 Jun 23.

Department of Neurology, Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea.

Background: Despite emerging evidence suggesting that visceral fat may play a major role in obesity-induced neurodegeneration, little evidence exists on the association between visceral fat and brain cortical thickness in the elderly.

Purpose: We aimed to examine the association between abdominal fat and brain cortical thickness in a Korean elderly population.

Methods: This cross-sectional study included elderly individuals without dementia ( = 316). Read More

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Form and content of Jamaican cannabis edibles.

J Cannabis Res 2021 Jul 10;3(1):29. Epub 2021 Jul 10.

Faculty of Medical Sciences Teaching and Research Complex (FMSTRC), University of the West Indies, Mona, Kingston, Jamaica.

Background: In 2017, the Jamaican government banned the sale of cannabis-infused edibles after reports of over-intoxication in adults and children. There is a general lack of public awareness regarding the risk involved with edible dosage. Vandrey et al. Read More

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TIFA protein expression is associated with pulmonary arterial hypertension.

Sci Rep 2021 Jul 8;11(1):14140. Epub 2021 Jul 8.

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Road, Beitou District, Taipei, Taiwan.

Tumor necrosis factor receptor-associated factor-interacting protein with a forkhead-associated domain (TIFA), a key regulator of inflammation, may be involved in the pathogenesis of pulmonary arterial hypertension (PAH). A total of 48 PAH patients (age 50.1 ± 13. Read More

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Determinants and Predictors of Body Fat in Indian Children and Adolescents.

Indian J Pediatr 2021 Jul 8. Epub 2021 Jul 8.

Department of Pediatric Endocrinology, Regency Center for Diabetes Endocrinology & Research, Regency City Clinic, The Mall, Kanpur, Uttar Pradesh, 208001, India.

Objective: To study determinants and predictors of body fat in Indian children and adolescents.

Methods: In this cross-sectional study, 5175 children and adolescents [3014 boys, age 12.8 (3) y, 5-18 y] participated. Read More

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