Am J Gastroenterol 2021 Apr;116(4):700-709
1Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA; 2Division Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah, USA; 3Division Gastroenterology and Hepatology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA; 4Borland-Groover Clinic, Jacksonville, Florida, USA; 5Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA; 6Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA; 7Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburg, Pennsylvania, USA; 8Division of Gastroenterology, Hepatology and Nutrition, The Ohio state University Wexner Medical Center, Columbus, Ohio, USA; 9Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA; 10Biostatistics & Bioinformatics Shared Resource, Winship Cancer Institute of Emory University, Atlanta, Georgia, USA; 11Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Introduction: Endoscopic necrosectomy has emerged as the preferred treatment modality for walled-off pancreatic necrosis. This study was designed to evaluate the safety and efficacy of direct endoscopic necrosectomy with and without hydrogen peroxide (H2O2) lavage.
Methods: Retrospective chart reviews were performed for all patients undergoing endoscopic transmural management of walled-off pancreatic necrosis at 9 major medical centers from November 2011 to August 2018. Read More