20,408 results match your criteria higher bulk

Nutrient composition of mealtimes and its association with the energy intake of subsequent meals among Mexican adults.

Appetite 2021 May 5:105288. Epub 2021 May 5.

CONACYT-Center for Nutrition and Health Research, National Institute of Public Health. 7a Cerrada de Fray Pedro de Gante No. 50, Col. Sección XVI, Tlalpan, Mexico City, Mexico, CP, 14080. Electronic address:

The composition of the diet influences energy intake by affecting satiety. Macronutrients have a hierarchical effect on satiety, where proteins have the greatest influence, followed by carbohydrates and fats. Alcohol consumption has also shown an effect on increasing energy intake in subsequent meals. Read More

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Changes in soil water holding capacity and water availability following vegetation restoration on the Chinese Loess Plateau.

Sci Rep 2021 May 7;11(1):9692. Epub 2021 May 7.

State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau, Institute of Soil and Water Conservation, Chinese Academy of Sciences and Ministry of Water Resources, Yangling, 712100, Shaanxi, People's Republic of China.

Changes in land use type can lead to variations in soil water characteristics. The objective of this study was to identify the responses of soil water holding capacity (SWHC) and soil water availability (SWA) to land use type (grassland, shrubland and forestland). The soil water characteristic curve describes the relationship between gravimetric water content and soil suction. Read More

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The oncogenic E3 ligase TRIP12 suppresses epithelial-mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2.

Cell Death Discov 2021 May 7;7(1):95. Epub 2021 May 7.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.

Thyroid hormone receptor interactor 12 (TRIP12) is an E3 ligase most notably involved in the proteolytic degradation of the tumor suppressor p14ARF. Through this process, it is proposed that TRIP12 plays an oncogenic role in tumor initiation and growth. However, its role in other cancer processes is unknown. Read More

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Nitrous oxide emission from full-scale municipal aerobic granular sludge.

Water Res 2021 Apr 19;198:117159. Epub 2021 Apr 19.

Department of Biotechnology, Delft University of Technology, Van der Maasweg 9, Delft 2629 HZ, the Netherlands; Royal HaskoningDHV, Laan1914 35, Amersfoort 3800 AL, the Netherlands.

The nitrous oxides emission was measured over 7 months in the full-scale aerobic granular sludge plant in Dinxperlo, the Netherlands. Nitrous oxide concentrations were measured in the bulk liquid and the off-gas of the Nereda® reactor. Combined with the batch wise operation of the reactor, this gave a high information density and a better insight into NO emission in general. Read More

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Optical Distance Measurement Based on Induced Nonlinear Photoresponse of High-Performance Organic Near-Infrared Photodetectors.

ACS Appl Mater Interfaces 2021 May 7. Epub 2021 May 7.

Dresden Integrated Center for Applied Physics and Photonic Materials (IAPP) and Institute for Applied Physics, Technische Universität Dresden, Nöthnitzer Str. 61, 01187 Dresden, Germany.

Extraction barriers are usually undesired in organic semiconductor devices since they lead to reduced device performance. In this work, we intentionally introduce an extraction barrier for holes, leading to nonlinear photoresponse. The effect is utilized in near-infrared (NIR) organic photodetectors (OPDs) to perform distance measurements, as delineated in the focus-induced photoresponse technique (FIP). Read More

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GEO Data Mining Identifies OLR1 as a Potential Biomarker in NSCLC Immunotherapy.

Front Oncol 2021 20;11:629333. Epub 2021 Apr 20.

Department of Cellular and Molecular Biology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. The tumor immune microenvironment (TME) in NSCLC is closely correlated to tumor initiation, progression, and prognosis. TME failure impedes the generation of an effective antitumor immune response. Read More

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Removal of bisphenol A from aqueous media using a highly selective adsorbent of hybridization cyclodextrin with magnetic molecularly imprinted polymer.

R Soc Open Sci 2021 Mar 10;8(3):201604. Epub 2021 Mar 10.

Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Penang, Malaysia.

In this study, a unique magnetic molecularly imprinted polymer (MMIP) adsorbent towards bisphenol A (BPA) as a template molecule was developed by bulk polymerization using β-cyclodextrin (β-CD) as a co-monomer with methacrylic acid (MAA) to form MMIP MAA-βCD as a new adsorbent. β-CD was hybridized with MAA to obtain water-compactible imprinting sites for the effective removal of BPA from aqueous samples. Benzoyl peroxide and trimethylolpropane trimethacrylate were used as the initiator and cross-linker, respectively. Read More

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Performance and Diagnostic Value of Genome-Wide Noninvasive Prenatal Testing in Multiple Gestations.

Obstet Gynecol 2021 May 6. Epub 2021 May 6.

Department of Human Genetics, Katholieke Universiteit Leuven, Leuven, the Center for Human Genetics and the Department of Obstetrics and Gynecology, Universitair Ziekenhuis Leuven, Leuven, the Center for Medical Genetics, Universitair Ziekenhuis Gent, Ghent, the Center for Medical Genetics, Universitair Ziekenhuis Antwerpen, Antwerp, the Center for Medical Genetics, Universiteit Antwerpen, Antwerp, the Center for Medical Genetics, Centre Hospitalier Universitaire de Liège, Liège, the Center for Human Genetics, Université Libre de Bruxelles, Brussels, the Center for Human Genetics, Université Catholique de Louvain, Brussels, the Center for Medical Genetics, Institut de Pathologie et de Génétique Gosselies, Charleroi, the Center for Medical Genetics, Vrije Universiteit Brussel, Brussels, and the Department of Obstetrics, Women's Clinic, Universitair Ziekenhuis Gent, Ghent, Belgium.

Objective: To evaluate the accuracy and diagnostic value of genome-wide noninvasive prenatal testing (NIPT) for the detection of fetal aneuploidies in multiple gestations, with a focus on dichorionic-diamniotic twin pregnancies.

Methods: We performed a retrospective cohort study including data from pregnant women with a twin or higher-order gestation who underwent genome-wide NIPT at one of the eight Belgian genetic centers between November 1, 2013, and March 1, 2020. Chorionicity and amnionicity were determined by ultrasonography. Read More

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Ambient urban N deposition drives increased biomass and total plant N in two native prairie grass species in the U.S. Southern Great Plains.

PLoS One 2021 6;16(5):e0251089. Epub 2021 May 6.

Department of Biology, University of Texas Arlington, Arlington, Texas, United States of America.

Remnants of native tallgrass prairie experience elevated atmospheric nitrogen (N) deposition in urban areas, with potential effects on species traits that are important for N cycling and species composition. We quantified bulk (primarily wet) inorganic N (NH4+-N + NO3--N) deposition at six sites along an urban development gradient (6-64% urban) in the Dallas-Fort Worth metropolitan area from April 2014 to October 2015. In addition, we conducted a phytometer experiment with two common native prairie bunchgrass species--one well studied (Schizachyrium scoparium) and one little studied (Nasella leucotricha)--to investigate ambient N deposition effects on plant biomass and tissue quality. Read More

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Contrasting Patterns of the Resident and Active Rhizosphere Bacterial Communities of Phragmites Australis.

Microb Ecol 2021 May 6. Epub 2021 May 6.

State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, 73 East Beijing Road, Nanjing, 210008, China.

Rhizosphere microbes play a key role in maintaining plant health and regulating biogeochemical cycles. The active bacterial community (ABC) in rhizosphere, as a small fraction of the rhizosphere resident bacterial community (RBC), has the potential to actively participate in nutrient cycling processes at the root-sediment interface. Here, we investigated the ABC and RBC within the rhizosphere of Phragmites australis (P. Read More

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Structural evolution in thermoelectric zinc antimonide thin films studied by X-ray scattering techniques.

IUCrJ 2021 May 13;8(Pt 3):444-454. Epub 2021 Apr 13.

Center for Materials Crystallography, Department of Chemistry and iNANO, Aarhus University, Aarhus C, DK-8000, Denmark.

Zinc antimonides have been widely studied owing to their outstanding thermoelectric properties. Unlike in the bulk state, where various structurally unknown phases have been identified through their specific physical properties, a number of intermediate phases in the thin-film state remain largely unexplored. Here, X-ray diffraction and X-ray total scattering are combined with measurement of electrical resistivity to monitor the crystallization process of as-deposited amorphous Zn-Sb films during post-deposition annealing. Read More

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A hierarchical clustering method of hydrogen bond networks in liquid water undergoing shear flow.

Sci Rep 2021 May 5;11(1):9542. Epub 2021 May 5.

State Key Laboratory of Hydro-Science and Engineering, Department of Hydraulic Engineering, Tsinghua University, Beijing, 100084, China.

Many properties of water, such as turbulent flow, are closely related to water clusters, whereas how water clusters form and transform in bulk water remains unclear. A hierarchical clustering method is introduced to search out water clusters in hydrogen bonded network based on modified Louvain algorithm of graph community. Hydrogen bonds, rings and fragments are considered as 1st-, 2nd-, and 3rd-level structures, respectively. Read More

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Degradation in order: simple and versatile one-pot combination of two macromolecular concepts to encode diverse and spatially regulated degradability functions.

Tiziana Fuoco

Angew Chem Int Ed Engl 2021 May 5. Epub 2021 May 5.

Kungliga Tekniska Hogskolan, Fibre and Polymer Technology, Teknikringen 56-58, 10044, Stockholm, SWEDEN.

The clever one-pot combination of two macromolecular concepts, ring-opening polymerization (ROP) and step-growth polymerization (SGP), is demonstrated to be a simple yet, powerful tool to design a library of sequence-controlled polymers with diverse and spatially regulated degradability functions. ROP and SGP, sequentially, occur at room temperature by switching the organo-catalytic conditions from basic to acidic, each allowing the encoding of specific degradable bonds. The ROP controls the sequence length and position of the degradability functions, while the SGP between the complementary vinyl ether and hydroxyl chain-end, enables the formation of acetal bonds and high molar mass copolymers. Read More

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Uncertainty of exchange-correlation functionals in density functional theory calculations for lithium-based solid electrolytes on the case study of lithium phosphorus oxynitride.

J Comput Chem 2021 May 5. Epub 2021 May 5.

Institute of Physical Chemistry, Justus-Liebig University Giessen, Giessen, Germany.

Amorphous lithium phosphorus oxynitride (LIPON) has emerged as a promising solid electrolyte for all-solid-state thin-film lithium batteries. In this context, the use of theoretical modeling to characterize, understand, or screen material properties is becoming increasingly important to complement experimental analysis or elucidate features at atomistic level that are difficult to obtain through experimental studies. Density functional theory (DFT) is the method of choice for quantum mechanical material modeling at the atomistic scale. Read More

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Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values, and antioxidant activity of shiitake mushroom.

J Sci Food Agric 2021 May 5. Epub 2021 May 5.

Department of Traditional Chinese Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China.

Background: Shiitake mushroom is one of the most popular delicious vegetables, but fresh shiitake mushroom has short shelf life due to biochemical degradation. Drying can prolong the shelf life of mushroom. Additionally, application of cold plasma pretreatments (CPT) before drying can preserve the product quality, processing cost, and nutritional values. Read More

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Collapse-induced phase transitions in binary interfacial microgel monolayers.

Soft Matter 2021 May;17(17):4504-4516

Institute of Particle Technology, Friedrich-Alexander University Erlangen-Nürnberg, Cauerstrasse 4, 91058 Erlangen, Germany.

Microgels, consisting of a swollen polymer network, exhibit a more complex self-assembly behavior compared to incompressible colloidal particles, because of their ability to deform at a liquid interface or collapse upon compression. Here, we investigate the collective phase behavior of two-dimensional binary mixtures of microgels confined at the air/water interface. We use stimuli-responsive poly(N-isopropylacrylamide) microgels with different crosslinking densities, and therefore different morphologies at the interface. Read More

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Floating particles with high copper concentration in the sea-surface microlayer.

Environ Sci Pollut Res Int 2021 May 4. Epub 2021 May 4.

School of Spatial Planning and Development, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

This study sought to clarify whether suspended particles containing high Cu concentrations are present in the sea-surface microlayer (S-SML). For this reason, suspended particles (10-2000 μm) in the S-SML were collected periodically from a ship mooring pond during 2018-2020, and the acid-soluble Cu concentration in the suspended particles was measured as particulate Cu (P-Cu). The highest concentration of P-Cu in the S-SML of the pond was 75 μg L with a 90th percentile value of 2. Read More

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Angiogenesis is associated with an attenuated tumor microenvironment, aggressive biology, and worse survival in gastric cancer patients.

Am J Cancer Res 2021 15;11(4):1659-1671. Epub 2021 Apr 15.

Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center Buffalo, New York 14263, USA.

Angiogenesis is a cornerstone of cancer as it allows tumors to receive oxygen and nutrients. A high level of angiogenesis within a tumor may therefore be indicative of its aggressiveness. In this study, we examined this hypothesis in gastric cancer. Read More

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Floquet Second-Order Topological Phases in Momentum Space.

Longwen Zhou

Nanomaterials (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

Department of Physics, College of Information Science and Engineering, Ocean University of China, Qingdao 266100, China.

Higher-order topological phases (HOTPs) are characterized by symmetry-protected bound states at the corners or hinges of the system. In this work, we reveal a momentum-space counterpart of HOTPs in time-periodic driven systems, which are demonstrated in a two-dimensional extension of the quantum double-kicked rotor. The found Floquet HOTPs are protected by chiral symmetry and characterized by a pair of topological invariants, which could take arbitrarily large integer values with the increase of kicking strengths. Read More

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Sequential Modulation of the Equine Fecal Microbiota and Fibrolytic Capacity Following Two Consecutive Abrupt Dietary Changes and Bacterial Supplementation.

Animals (Basel) 2021 Apr 29;11(5). Epub 2021 Apr 29.

Unité Mixte de Recherche Procédés Alimentaires et Microbiologiques (UMR PAM) A 02.102, AgroSup Dijon, University Bourgogne Franche-Comté, 21000 Dijon, France.

In horses, abrupt changes from high-fiber (HF) to high-starch (HS) diets can affect the cecal and colonic microbiota. This study investigated modifications and recovery of fecal microbiota after two consecutive abrupt dietary changes. Twelve horses fed HF for 2 weeks were changed to HS for 5 days then returned to HF for 7 weeks. Read More

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Polydispersity vs. Monodispersity. How the Properties of Ni-Ag Core-Shell Nanoparticles Affect the Conductivity of Ink Coatings.

Materials (Basel) 2021 Apr 29;14(9). Epub 2021 Apr 29.

Jerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Niezapominajek 8, 30239 Kraków, Poland.

The effect of polydispersity of nickel-silver core-shell nanoparticles (Ni-Ag NPs) on the conductivity of ink coatings was studied. Ni-Ag NPs of various average diameters (100, 220, and 420 nm) were synthesized and utilized for the preparation of conductive inks composed of monodisperse NPs and their polydisperse mixtures. The shell thickness of synthesized Ni-Ag NPs was found to be in the range of 10-20 nm and to provide stability of a core metal to oxidation for at least 6 months. Read More

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Photocross-Linked Antimicrobial Amino-Siloxane Elastomers.

ACS Appl Mater Interfaces 2021 May 4. Epub 2021 May 4.

Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.

Mechanically robust bulk antimicrobial polymers are one way to address disease transmission via contaminated surfaces. Here, we demonstrate the visible light photo-oxidative cross-linking of amine-containing PDMS using a single-component, solvent-free system where amines have a dual role as antimicrobial functionalities and cross-linking sites. Rose Bengal, a xanthene dye used as a fluorescent stain, is thermally reacted with the polymer to give a solvent-free liquid siloxane that can generate reactive singlet oxygen upon aerobic green light irradiation, coupling the amine functionalities into imine cross-links. Read More

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News from Mars: Two-Tier Paradox, Intracellular PCR, Chimeric Junction Shift, Dark Matter mRNA and Other Remarkable Features of Mammalian RNA-Dependent mRNA Amplification. Implications for Alzheimer's Disease, RNA-Based Vaccines and mRNA Therapeutics.

Ann Integr Mol Med 2021 ;2:131-173

Division of Molecular Medicine, Children's Hospital, USA.

Molecular Biology, a branch of science established to examine the flow of information from "letters" encrypted into DNA structure to functional proteins, was initially defined by a concept of DNA-to-RNA-to-Protein information movement, a notion termed the Central Dogma of Molecular Biology. RNA-dependent mRNA amplification, a novel mode of eukaryotic protein-encoding RNA-to-RNA-to-Protein genomic information transfer, constitutes the extension of the Central Dogma in the context of mammalian cells. It was shown to occur in cellular circumstances requiring exceptionally high levels of production of specific polypeptides, e. Read More

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January 2021

Association of dietary fiber and risk of hip fracture in men from the Framingham Osteoporosis Study and the Concord Health and Ageing in Men Project.

Nutr Health 2021 May 4:2601060211011798. Epub 2021 May 4.

Centre for Health Systems and Safety Research, Australian Institute of Health Innovation Faculty of Medicine, Health and Human Sciences, Macquarie University, NSW 2109, Australia.

Background: Data in the Offspring Framingham Osteoporosis Study (FOS) suggested that higher intake of dietary fiber was modestly protective against loss of bone mineral density at the femoral neck in men but not in women.

Aim: To examine the relationship of fiber intake with risk of hip fractures in men.

Methods: We included 367 men from the FOS Original cohort, 1730 men from the FOS Offspring cohort, and 782 men from the Concord Health and Ageing in Men Project (CHAMP) in the analysis. Read More

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Confinement effects on the solvation structure of solvated alkaline metal cations in a single-digit 1T-MoS nanochannel: A first-principles study.

J Chem Phys 2021 Apr;154(16):164706

Material Science Division, Lawrence Livermore National Laboratory, Livermore, California 94550, USA.

Confinement plays an important role in determining ion transport in porous materials, which, in turn, may influence the performance of many energy storage and desalination devices. In this work, we combined density functional theory (DFT) with an implicit solvation model and ab initio molecular dynamics (AIMD) to investigate the effects of nanoconfinement on several solvated alkaline metal cations in a single-digit 1T-MoS nanochannel. Our DFT calculations with a solvation model indicated that cations with stronger hydration energy introduce a higher number of co-intercalated water molecules into the channel, consistent with early experimental observation obtained for MXene (2D transition metal carbide) channels. Read More

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Solar to hydrocarbon production using metal-free water-soluble bulk heterojunction of conducting polymer nanoparticle and graphene oxide.

J Chem Phys 2021 Apr;154(16):164707

Center for Condensed Matter Sciences, National Taiwan University, Taipei, Taiwan.

This work demonstrates the first example of interfacial manipulation in a hybrid photocatalyst based on poly(3-hexylthiophene-2,5-diyl) (P3HT) nanoparticle and graphene oxide (GO) bulk heterojunctions to efficiently reduce CO into selective industrial hydrocarbons under gas-phase reaction and visible-light illumination. High selectivity of chemical products (methanol and acetaldehyde) was observed. Moreover, the hybrid photocatalyst's solar-to-fuel conversion efficiency was 13. Read More

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The study of the chromatographic behavior and a mass spectrometric approach to differentiating the diastereomer pair of the β-O-4 lignin dimer series.

Anal Bioanal Chem 2021 May 2. Epub 2021 May 2.

Department of Chemistry, University of Kentucky, Lexington, KY, 40506, USA.

Lignin and lignans are natural products found in plant cell walls. Lignin research has historically focused on lignin degradation techniques in the hope of converting lignin into useful aromatic carbon feedstocks. In contrast, investigations of lignans existing as natural product dimers, have been focused on thier interesting biological activities. Read More

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Epidemiological study of Coxiella burnetii in dairy cattle and small ruminants in Québec, Canada.

Prev Vet Med 2021 Apr 25;191:105365. Epub 2021 Apr 25.

Groupe de recherche en épidémiologie des zoonoses et santé publique (GREZOSP), Faculté de médecine vétérinaire, Université de Montréal, 3200 Sicotte, St-Hyacinthe, Québec, J2S 2M2, Canada; Faculté de médecine vétérinaire, Université de Montréal, 3200 Sicotte, St-Hyacinthe, Québec, J2S 2M2, Canada; Swine and Poultry Infectious Diseases Research Center (CRIPA) - Fonds de Recherche du Québec, Faculté de médecine vétérinaire, Université de Montréal, 3200 Sicotte, St-Hyacinthe, Québec, J2S 2M2, Canada. Electronic address:

The bacterium Coxiella burnetii (C. burnetii) can infect a wide range of animals, most notably ruminants where it causes mainly asymptomatic infections and, when clinical, it is associated with reproductive disorders such as abortion. It is also the etiological agent of Q fever in humans, a zoonosis of increasingly important public health concern. Read More

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Relevance of dietary glycemic index, glycemic load and fiber intake before and during pregnancy for the risk of gestational diabetes mellitus and maternal glucose homeostasis.

Clin Nutr 2021 Apr 5;40(5):2791-2799. Epub 2021 Apr 5.

Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address:

Background & Aims: To date, the prevalence of Gestational diabetes mellitus (GDM) in China was 17.5%. Given the substantial relevance of GDM for medium- and long-term health of both mother and offspring and the paucity of existing data on the link between maternal diet and glucose homeostasis during pregnancy in Asian population, additional studies are needed. Read More

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Dietary fiber deficiency as a component of malnutrition associated with psychological alterations in alcohol use disorder.

Clin Nutr 2021 Mar 30;40(5):2673-2682. Epub 2021 Mar 30.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, UCLouvain, Brussels, Belgium. Electronic address:

Background & Aims: Chronic alcohol consumption can cause malnutrition that may contribute to alcohol-induced organ injury and psychological disorders. We evaluated the link between nutrient intake, especially dietary fibers (DF) and different parameters reflecting mental health and well being, namely anxiety, depression, alcohol craving, sociability, fatigue and intestinal comfort in alcohol use disorder (AUD) patients.

Methods: Cross-sectional data from 50 AUD patients, hospitalized for a 3-week detoxification program were used. Read More

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