Ecotoxicol Environ Saf 2021 Apr 7;216:112202. Epub 2021 Apr 7.
Nature Research Centre, Laboratory of Geoenvironmental Research, Akademijos St. 2, LT-08412 Vilnius, Lithuania; Vilnius University, Faculty of Chemistry and Geosciences, Naugarduko St. 24, LT-03225 Vilnius, Lithuania.
The present study tested the biological consequences of exposure to a multimetal mixture as a multiple chemical stressor on Oncorhynchus mykiss at molecular, cellular, physiological and whole-organism levels and on biomarker responses of this fish during the depuration period. To represent environmentally relevant multiple chemical stressors, in our study, we used the mixture of Zn, Cu, Ni, Cr, Pb and Cd at the concentrations corresponding to Maximum-Permissible-Concentrations (MPCs) acceptable for the EU inland waters. This study was undertaken with a view to elucidate if changes in the MPC of the test mixture components (Ni, Pb, Cd) could cause significantly different biomarker responses in O. Read More