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Obesity and the Risk of Infertility, Gestational Diabetes, and Type 2 Diabetes in Polycystic Ovary Syndrome.

Semin Reprod Med 2021 Apr 19. Epub 2021 Apr 19.

Monash Centre for Health Research and Implementation, Monash University, Victoria, Australia.

This review describes the relationship between obesity and the most common reproductive (infertility) and metabolic (gestational diabetes mellitus [GDM] and type 2 diabetes mellitus [T2DM]) consequences in polycystic ovary syndrome (PCOS). It also describes the vital role of lifestyle management for PCOS. PCOS is a heterogeneous endocrine disorder common in reproductive-age women. Read More

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Injuries after Forklift Trucks Accidents - Injury Patterns, Therapy and Outcome in the Context of the Statutory Accident Insurance.

Z Orthop Unfall 2021 Apr 19. Epub 2021 Apr 19.

Department of General and Trauma Surgery, BG University Hospital, Bochum, Germany.

Introduction: The use of forklift trucks during work has a high accident potential. The aim of this study is to describe injury patterns, treatment and outcome after forklift truck accidents in the context of the employers' liability insurance association.

Methods: Retrospective data collection of all cases between 2004 and 2019. Read More

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Anterior Locking Plate Osteosynthesis of Patellar Factures - Analysis of Complications and Functional Outcome.

Z Orthop Unfall 2021 Apr 19. Epub 2021 Apr 19.

Orthopaedic Clinic, Hannover Medical University (MHH), DIAKOVERE Annastift, Hannover, Germany.

Background: Tension band wiring is the standard procedure for patellar fractures, but is associated with a high rate of implant related complications and implant failure. Tension band wiring may fail, especially with multifragmentary and comminuted fractures. Plate fixation of complex patellar fractures seems to be superior to wiring, both clinically and biomechanically. Read More

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Insufficiency Fractures vs. Low-Energy Pelvic Ring Fractures - Epidemiological, Diagnostic and Therapeutic Characteristics of Fragility Fractures of the Pelvic Ring.

Z Orthop Unfall 2021 Apr 19. Epub 2021 Apr 19.

Department of Trauma and Orthopaedic Surgery, Erlangen University Medical Centre, Erlangen, Germany.

Background: Fragility fractures of the pelvis (FFP) encompass two fracture entities: fracture after low-energy trauma and insufficiency fracture without trauma. It is unclear whether the two subgroups differ in terms of diagnosis and therapy. The aim of this retrospective study was to evaluate insufficiency fractures with regard to defined parameters and to compare specific parameters with the fractures after low-energy trauma. Read More

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How Safe and Time Consuming is the Surgical Training of Young Orthopaedic Surgeons? A Retrospective Analysis of Proximal Femur Fractures.

Z Orthop Unfall 2021 Apr 19. Epub 2021 Apr 19.

Department of Trauma, Hand and Reconstructive Surgery, University of Ulm, Germany.

Background: Fractures of the proximal femur in the elderly population are rising. Teaching the appropriate surgical treatment of these fractures is of paramount importance. The aim of the study was to evaluate differences in outcome of surgical procedures between supervised trainees and senior surgeons. Read More

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Identification of Potential High-Risk Patients on the Basis of PROMs in a Certified Centre for Joint Replacement (EndoProthetikZentrum) Using the Example of Hip Arthroplasty.

Z Orthop Unfall 2021 Apr 19. Epub 2021 Apr 19.

Department of Orthopaedics, Rostock University Medical Centre, Germany.

Background: In addition to clinical parameters, the subjective assessment by the patient to evaluate the operative outcome of an arthroplasty is becoming increasingly important. Questionnaires are used to identify patients who have not achieved the treatment goal at an early stage so that further interventions can be indicated.

Material And Methods: A questionnaire consisting of different PROMs was completed pre- and 3 months postoperatively by patients who had been treated with a hip arthroplasty. Read More

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Agreement between the Skull Vibration-Induced Nystagmus Test and Semicircular Canal and Otolith Asymmetry.

J Am Acad Audiol 2021 Apr 19. Epub 2021 Apr 19.

Vestibular and Balance Program, Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota.

Background:  How significant asymmetries in otolith organ function in the presence of symmetrical and asymmetrical semicircular canal function influence skull vibration-induced nystagmus testing (SVINT) has not been well described.

Purpose:  The aim of the study is to examine the agreement between SVINT and caloric testing, ocular vestibular-evoked myogenic potentials (oVEMP), and cervical vestibular-evoked myogenic potentials (cVEMP) for detecting asymmetric vestibular function.

Research Design:  This is a retrospective study of patients presenting with the chief complaint of vertigo, dizziness, or imbalance. Read More

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[Social Inequalities in Access to and Utilization of Medical Rehabilitation - Results of the Third German Sociomedical Panel of Employees (GSPE-III)].

Rehabilitation (Stuttg) 2021 Apr 19. Epub 2021 Apr 19.

Institut für Medizinische Soziologie, Martin-Luther-Universität Halle-Wittenberg.

Aim Of The Study: The influence of social status on health is well documented. Preliminary research provides initial evidence for social inequalities in rehabilitation care. Our study examines the role of social inequalities with respect to access and utilisation of medical rehabilitation services by analysing a risk cohort of the German Statutory Pension Insurance Scheme (Deutsche Rentenversicherung Bund). Read More

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[Update on diagnosis and therapy in frequent vestibular and balance disorders].

Fortschr Neurol Psychiatr 2021 Apr 19. Epub 2021 Apr 19.

LMU Klinikum, Neurologische Klinik und Deutsches Schwindel- und Gleichgewichtszentrum (DSGZ).

The 8 most frequent vestibular disorders account for more than 70% of all presentations of vertigo, dizziness, and imbalance. In acute (and mostly non-repetitive) vestibular disorders acute unilateral vestibulopathy and vestibular stroke are most important, in episodic vestibulopathies benign paroxysmal positional vertigo (BPPV), Menière's disease and vestibular migraine, and in chronic vestibular disorders bilateral vestibulopathy/presbyvestibulopathy, functional dizziness and cerebellar dizziness. In the last decade, internationally consented diagnostic criteria and nomenclature were established for the most frequent vestibular disorders, which can be easily applied in clinical practice. Read More

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[Orthokeratology - a Perfect Vision Overnight - An Update and Overview].

Klin Monbl Augenheilkd 2021 Apr 19. Epub 2021 Apr 19.

Orthokeratology offers the unique possibility of correcting myopia: a special reverse geometry contact lens used exclusively during sleeping hours at nighttime. The authors give a comprehensive overview about the evolving technique, including the careful selection of patients, and practical contact lens fitting. They explain a series of daily life situations and point out dos and don'ts. Read More

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Utility of True Fast Imaging with Steady-State Precession in Detecting Arachnoid Veils of the Posterior Fossa.

Pediatr Neurosurg 2021 Apr 19:1-8. Epub 2021 Apr 19.

Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Introduction: Arachnoid membranes are well recognized as a cause of cerebrospinal fluid (CSF) flow impairment in disorders such as obstructive hydrocephalus and syringohydromyelia, but can be difficult to detect with standard noninvasive imaging techniques. True fast imaging with steady-state precession (TrueFISP) can exhibit brain pulsations and CSF dynamics with high spatiotemporal resolution. Here, we demonstrate the utility of this technique in the diagnosis and management of arachnoid membranes in the posterior fossa. Read More

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Baseline Characteristics and Survival of an Australian Interstitial Pneumonia with Autoimmune Features Cohort.

Respiration 2021 Apr 19:1-12. Epub 2021 Apr 19.

Department of Respiratory, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Background And Objective: The research term "interstitial pneumonia with autoimmune features" (IPAF) encompasses interstitial lung disease (ILD) patients with autoimmune features not meeting diagnostic criteria for a defined connective tissue disease (CTD). It remains unclear if IPAF is a distinct disease entity with implications for management and prognosis. We describe an Australian IPAF population and compare their baseline characteristics and outcomes with distinct cohorts of idiopathic interstitial pneumonia (IIP), CTD-ILD, and unclassifiable ILD. Read More

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Induction of Immune Responses and Immune Evasion by Human Bocavirus.

Int Arch Allergy Immunol 2021 Apr 19:1-8. Epub 2021 Apr 19.

Virology Research Group, Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

Respiratory tract infections are the primary cause of morbidity and mortality globally. Human bocavirus 1 (HBoV1), a member of the Parvoviridae family causes a wide spectrum of respiratory diseases in children, and gastroenteritis in adults. The mechanisms of latency, persistence, and reinfection of Bocavirus are poorly understood at present due to the lack of permissive cell lines and efficient animal models. Read More

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Microwave thermoacoustic tomographic (MTT) imaging.

Authors:
James C Lin

Phys Med Biol 2021 Apr 19. Epub 2021 Apr 19.

Department of Electrical Engineering & Computer Science, University of Illinois at Chicago, Science & Engineering Offices, 851 South Morgan Street (M/C 154), Chicago, IL 60607-7053, USA, Chicago, Illinois, 60607, UNITED STATES.

Microwave thermoacoustic tomography (MTT) uses microwave-pulse-induced thermoelastic pressure waves to form planar or tomographic images. Since the generation and detection of thermoelastic pressure waves depends on dielectric permittivity, specific heat, thermal expansion, and acoustic properties of tissue, microwave thermoacoustic imaging possesses the characteristic features of a duel-modality imaging system. The unique attributes of the high contrast offered by microwave absorption and the fine spatial resolution furnished by ultrasound are being explored to provide a nonionizing and noninvasive imaging modality for characterization of tissues, especially for early detection of breast cancer. Read More

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Spin correlations and spin-density wave phase in a finite-temperature quasi-one-dimensional electron gas.

J Phys Condens Matter 2021 Apr 19. Epub 2021 Apr 19.

Physics, Kurukshetra University Faculty of Science, Department of Physics, Kurukshetra University Kurukshetra, Haryana, INDIA, Kurukshetra, Haryana, 136119, INDIA.

In this paper, we theoretically investigate the effect of temperature on spin correlations in an unpolarized quasi-one-dimensional electron gas (Q1DEG). The correlations are treated dynamically within quantum version of the self-consistent mean-field approach of Singwi {\it et al}. Numerical results for the $\uparrow\uparrow$ and $\uparrow\downarrow$ components of static structure factor and pair-correlation function, and the wave vector dependent static spin and charge susceptibilities are presented over a wide range of temperature $T$ and electron coupling $r_s$. Read More

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Organic optical agents for image-guided combined cancer therapy.

Biomed Mater 2021 Apr 19. Epub 2021 Apr 19.

College of Life Sciences, Nankai University, 94 Weijin Road, Tianjin, 300071, CHINA.

As a promising non-invasive treatment method, phototherapy has attracted extensive attention in the field of combined cancer therapy. Among various optical agents, organic ones have been considered as a promising clinical phototheranostic agent due to its high safety and non-toxic property. In addition, due to the clear structure, facile processability, organic optical agents can be easily endowed with multiple imaging and phototherapeutic functions, significantly simplifying the relatively complex system of imaging-guided combined cancer therapy. Read More

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Biocompatibility of platinum-based bulk metallic glass in orthopedic applications.

Biomed Mater 2021 Apr 19. Epub 2021 Apr 19.

Department of Pathology, Yale University School of Medicine, 10 Amistad Str, new haven, 060520, UNITED STATES.

Bulk Metallic Glasses (BMGs) are a class of amorphous metals that exhibit high strength, ductility paired with wear and corrosion resistance. These properties suggest that they could serve as an alternative to conventional metallic implants that suffer wear and failure. In the present study, we investigated Platinum (Pt)-BMG biocompatibility in bone applications. Read More

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Size effect of hybrid carbon nanofillers on the synergetic enhancement of the properties of HDPE-based nanocomposites.

Nanotechnology 2021 Apr 19. Epub 2021 Apr 19.

Polymer Institute, Slovak Academy of Sciences - Polymer Institute, Dubravska cesta 9, Bratislava, S, Bratislava, 845 41, SLOVAKIA.

High-density polyethylene (HDPE)-based hybrid nanocomposites containing graphene nanoplatelets (GnPs) and multiwall carbon nanotubes (MWCNTs) were fabricated using melt mixing followed by compression molding. The influences of size and weight ratio of both carbon-based nanofillers on the electrical, thermal, and mechanical properties of hybrid nanocomposites were evaluated. This study proves that the size and weight ratio of carbon-based nanofillers play a critical role in determining these properties. Read More

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Ag@ZnO/MWCNT Ternary Nanocomposite as an Active and Stable Catalyst for the 4-Nitrophenol Reduction in Water.

Nanotechnology 2021 Apr 19. Epub 2021 Apr 19.

Universidad Autonoma de San Luis Potosi Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología, San Luis Potosi, 78210, MEXICO.

The nitroaromatic compounds, known as organic pollutants, have arising attention due to their carcinogenic character, highly dangerous to human health. In this work, the Ag@ZnO/MWCNT ternary nanocomposite synthesized via conjugation of sonochemical and solvothermal treatments manifests high performance in the reduction of 4-nitrophenol in the aqueous media (TOF value of 246 min-1mol-metal-1). The incorporation of MWCNT onto the nanocomposite structure favored the reusing of the catalysts even after eight consecutive catalytic runs without catalysts cleaning nor product removal. Read More

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A liquid scintillation analysis method for low-Level radioactive wastewater.

J Radiol Prot 2021 Apr 19. Epub 2021 Apr 19.

Xi'an Research Institute of High-Tech, Xi'an, CHINA.

There is currently general concern over low-level radioactive wastewater from the development of nuclear industry.In this paper, a method based on ultralow-level liquid scintillation spectrometer for measuring uranium radioactivity in low-level radioactive wastewater is proposed. This method can easily and quickly measure the radioactivity level of uranium in samples and can even distinguish the main isotopes of uranium. Read More

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Weaker McGurk Effect for Rubin's Vase-Type Speech in People With High Autistic Traits.

Multisens Res 2021 Apr 16:1-17. Epub 2021 Apr 16.

School of Psychology, Chukyo University, 101-2 Yagoto Honmachi, Showa-ku, Nagoya-shi, Aichi, 466-8666, Japan.

While visual information from facial speech modulates auditory speech perception, it is less influential on audiovisual speech perception among autistic individuals than among typically developed individuals. In this study, we investigated the relationship between autistic traits (Autism-Spectrum Quotient; AQ) and the influence of visual speech on the recognition of Rubin's vase-type speech stimuli with degraded facial speech information. Participants were 31 university students (13 males and 18 females; mean age: 19. Read More

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Water-Based Interventions for People With Neurological Disability, Autism, and Intellectual Disability: A Scoping Review.

Adapt Phys Activ Q 2021 Apr 19:1-20. Epub 2021 Apr 19.

University of South Australia.

The purpose of this study was to produce a descriptive overview of the types of water-based interventions for people with neurological disability, autism, and intellectual disability and to determine how outcomes have been evaluated. Literature was searched through MEDLINE, EMBASE, Ovid Emcare, SPORTDiscus, Google Scholar, and Google. One hundred fifty-three papers met the inclusion criteria, 115 hydrotherapy, 62 swimming, 18 SCUBA (self-contained underwater breathing apparatus), and 18 other water-based interventions. Read More

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Improvement of meat protein digestibility in infants and the elderly.

Food Chem 2021 Mar 26;356:129707. Epub 2021 Mar 26.

Division of Animal and Dairy Science, Chungnam National University, Daejeon 34134, South Korea. Electronic address:

Meat is a valuable protein source with a balanced composition of essential amino acids and various nutrients. This review aims to identify methods to improve digestion of meat proteins, as well as evaluate the digestive characteristics of infants and the elderly. Immature digestive conditions in infants, including a high gastric pH and low protease concentration, can hinder protein digestion, thus resulting in inhibited growth and development. Read More

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Changes in microbial communities and their predictive functionalities during fermentation of toddy, an alcoholic beverage of India.

Microbiol Res 2021 Apr 6;248:126769. Epub 2021 Apr 6.

DAICENTER (DBT-AIST International Centre for Translational and Environmental Research) and Bioinformatics Centre, Department of Microbiology, School of Life Sciences, Sikkim University, Gangtok, 737102, Sikkim, India. Electronic address:

Toddy is a traditional mild-alcoholic drink of India, which is produced from fresh palm saps by natural fermentation. We studied the successional changes in bacterial and fungal communities during the natural fermentation (0 h-96 h) of toddy. During fermentation, alcohol content of the fermenting saps increased significantly from 0. Read More

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The Association Between Physical Performance and Health-Related Quality of Life Based on the EuroQol 5-Dimensional Questionnaire in Patients With Chagas Disease.

Value Health Reg Issues 2021 Apr 15;25:112-117. Epub 2021 Apr 15.

Research Division, National Institute of Cardiology, Ministry of Health, Rio de Janeiro, Brazil; State University of Rio de Janeiro, Internal Medicine Department, Rio de Janeiro, Brazil. Electronic address:

Objectives: Chagas disease (CD) is a chronic disease to millions worldwide, and many patients develop heart disease. In addition, they are part of an aging population. These characteristics can be associated with a reduction in physical performance and health-related quality of life (HRQoL). Read More

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Integrated H NMR fingerprint with NIR spectroscopy, sensory properties, and quality parameters in a multi-block data analysis using ComDim to evaluate coffee blends.

Food Chem 2021 Mar 19;355:129618. Epub 2021 Mar 19.

Universidade Tecnológica Federal do Paraná, Campus Campo Mourão (UTFPR-CM), Campo Mourão, Paraná, Brazil. Electronic address:

Coffee quality is determined by several factors and, in the chemometric domain, the multi-block data analysis methods are valuable to study multiple information describing the same samples. In this industrial study, the Common Dimension (ComDim) multi-block method was applied to evaluate metabolite fingerprints, near-infrared spectra, sensory properties, and quality parameters of coffee blends of different cup and roasting profiles and to search relationships between these multiple data blocks. Data fusion-based Principal Component Analysis was not effective in exploiting multiple data blocks like ComDim. Read More

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Lower extremity muscle contributions to ACL loading during a stop-jump task.

J Biomech 2021 Apr 9;121:110426. Epub 2021 Apr 9.

Department of Kinesiology, Recreation, and Sport Studies, The University of Tennessee, Knoxville, TN, USA. Electronic address:

Landing is considered a high-risk movement, especially landings from a stop-jump task, as they are often associated with lower extremity injuries, such as anterior cruciate ligament injuries (ACL). Females demonstrate lower extremity landing mechanics that often place them at a larger risk of injury compared to their male counterparts. While efforts have been made to understand lower extremity mechanics during stop-jump landings, little is known regarding the musculature function during these tasks and how they may influence ACL loading. Read More

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Development of an in vitro test method to simulate intra-operative impaction loading on lumbar intervertebral body fusion devices.

J Biomech 2021 Apr 5;121:110412. Epub 2021 Apr 5.

U.S. Food and Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, Silver Spring, MD 20993, USA.

Intervertebral body fusion devices (IBFDs) are commonly used in the treatment of various spinal pathologies. Intra-operative fractures of polyether-ether-ketone (PEEK) implants have been reported in the literature and to the FDA as device-related adverse events. The device and/or implant inserter failures typically occur during device impaction into the disc space and require implant removal and replacement. Read More

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Anti-seizure medication correlated changes of cortical morphology in childhood epilepsy with centrotemporal spikes.

Epilepsy Res 2021 Mar 23;173:106621. Epub 2021 Mar 23.

Department of Medical Imaging, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, 210002, China; Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002, China; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, 210093, China; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 Thirteenth Street, Suite 2301, Charlestown, MA, 02129, USA. Electronic address:

To investigate the morphological changes of cerebral cortex correlating with anti-seizure medication in Childhood Epilepsy with Centrotemporal Spikes (CECTS), and their relationships with seizure control. This study included a total of 188 children, including 62 patients with CECTS taking anti-seizure drugs, 56 patients with drug-naive, and 70 healthy controls. A portion of cases were also followed-up for longitudinal analysis. Read More

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Prevalence and associations of co-morbid insomnia and sleep apnoea in an Australian population-based sample.

Sleep Med 2021 Mar 31;82:9-17. Epub 2021 Mar 31.

The Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute: Sleep Health, College of Medicine and Public Health, Flinders University, SA, 5042, Australia.

Introduction: Insomnia and obstructive sleep apnoea (OSA) are the two most prevalent sleep disorders, and frequently co-occur (COMISA) in sleep clinic samples. However, few studies have investigated the prevalence or associations of COMISA in the general population.

Methods: We used population-based online survey data from 2044 Australian adults. Read More

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