53,615 results match your criteria high mobility


Hydrogen Bonding Strength Determines Water Diffusivity in Polymer Ionogels.

J Phys Chem B 2021 May 12. Epub 2021 May 12.

Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara 93106-9010, United States.

Polymeric ionogels, cross-linked gels swollen by ionic liquids (ILs), are useful vehicles for the release and storage of molecular solutes in separation, delivery, and other applications. Although rapid solute diffusion is often critical for performance, it remains challenging to predict diffusivities across multidimensional composition spaces. Recently, we showed that water (a neutral solute) diffuses through alkyl-methylimidazolium halide ILs by hopping between hydrogen bonding sites on relatively immobile cations. Read More

View Article and Full-Text PDF

Social mobility and healthy behaviours from a gender perspective in the Spanish multicase-control study (MCC-Spain).

PLoS One 2021 12;16(5):e0251447. Epub 2021 May 12.

Cancer and Public Health Area, Foundation for the Promotion of the Research in Healthcare and Biomedicine (FISABIO-Salud Pública), Valencia, Valencian Community, Spain.

There is evidence for the influence of socioeconomic status (SES) on healthy behaviours but the effect of social mobility (SM) is not yet well known. This study aims to analyse the influence of origin and destination SES (O-SES and D-SES) and SM on healthy behaviours and co-occurrence, from an integrated gender and age perspective. Data were obtained from the controls of MCC-Spain between 2008-2013 (3,606 participants). Read More

View Article and Full-Text PDF

Generating an Adaptive and Robust Walking Pattern for a Prosthetic Ankle-Foot by Utilizing a Nonlinear Autoregressive Network With Exogenous Inputs.

IEEE Trans Neural Netw Learn Syst 2021 May 12;PP. Epub 2021 May 12.

One of the major challenges in developing powered lower limb prostheses is emulating the behavior of an intact lower limb with different walking speeds over diverse terrains. Numerous studies have been conducted on control algorithms in the field of rehabilitation robotics to achieve this overarching goal. Recent studies on powered prostheses have frequently used a hierarchical control scheme consisting of three control levels. Read More

View Article and Full-Text PDF

Multicomponent compression system use in patients with chronic venous insufficiency: a real-life prospective study.

J Wound Care 2021 May;30(5):400-412

Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany.

Objective: Compression therapy is the cornerstone of therapeutic management of patients with chronic venous insufficiency (CVI). This study aimed to evaluate the efficacy and safety of a multicomponent compression system in an unselected population of patients with CVI problems under real-life conditions.

Method: A prospective, multicentre, observational study with a multicomponent two-bandage compression system (UrgoK2, Laboratoires Urgo, France) was conducted in 103 centres in Germany. Read More

View Article and Full-Text PDF

hsa_circ_0062019 promotes the proliferation, migration, and invasion of prostate cancer cells via the miR-195-5p/HMGA2 axis.

Acta Biochim Biophys Sin (Shanghai) 2021 May 12. Epub 2021 May 12.

Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.

Circular RNA (circRNA) is a new class of non-coding RNA. It was reported that circRNA involves in the metastasis of cancer. The aim of this study is to explore the role and mechanism of circRNA hsa_circ_0062019 in the development of prostate cancer (PCa). Read More

View Article and Full-Text PDF

Fabry-Perot cavity enhanced three-photon luminescence of atomically thin platinum diselenide.

Nanoscale 2021 May 11. Epub 2021 May 11.

Institute of Photonic Chips, University of Shanghai for Science and Technology, Shanghai 200093, China and Centre for Artificial-Intelligence Nanophotonics, School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.

Two-dimensional materials, such as transition metal dichalcogenides (TMDs), exhibit intriguing physical properties that lead to both fundamental research and technology development. The recently emerged platinum diselenide (PtSe2), as a new member of the TMDs, has attracted increasing attention because of its good air stability, large refractive index and high electron mobility. However, being atomically thin significantly hinders its interaction with light, severely limiting the spontaneous or stimulated linear and nonlinear emission. Read More

View Article and Full-Text PDF

Effectiveness of exercise therapy versus occlusal splint therapy for the treatment of painful temporomandibular disorders: a systematic review and meta-analysis.

Ann Palliat Med 2021 May 10. Epub 2021 May 10.

Department of Rehabilitation, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

Background: This systematic review of the literature was to compare the effects of exercise therapy and occlusal splint therapy on pain and mobility in individuals with painful temporomandibular disorders (TMD).

Methods: PubMed, Embase and the Cochrane Central Register of Controlled Trials were searched for English publications from database root to March 1, 2020. Search terms were [("temporomandibular joint disorders" or "temporomandibular disorders" or "craniomandibular disorders" or "orofacial pain" or "myofascial pain" or "myofascial pain" or "facial pain") AND (exercise or "physical therapy modalities" or physiotherapy or "exercise therapy") AND ("splints" or "occlusal splints" or "stabilization splint" or "occlusal appliance" or "occlusal splint therapy")]. Read More

View Article and Full-Text PDF

High-Performance Full-Photolithographic Top-Contact Conformable Organic Transistors for Soft Electronics.

Adv Sci (Weinh) 2021 May 18;8(9):2004050. Epub 2021 Feb 18.

Center for Advanced Optoelectronic Functional Materials Research and Key Lab of UV-Emitting Materials and Technology of Ministry of Education Northeast Normal University 5268 Renmin Street Changchun 130024 China.

Organic thin-film transistors (OTFTs) are identified to be the most promising candidate for next-generation wearable and implantable electronics because of their unique advantages including their flexibility, low cost, long-term biocompatibility, and simple packaging. However, commercialization of organic transistors remains an enormous challenge due to their low mobility and lack of scalable strategy for high-precise soft devices. Here, a novel photolithography fabrication strategy is proposed, which is completely compatible with various commercial organic semiconductor materials, for the first demonstration of the fully photolithographic top-contact conformable OTFTs with the device density as high as 1523 transistors cm. Read More

View Article and Full-Text PDF

RNA-binding protein YBX1 promotes cell proliferation and invasiveness of nasopharyngeal carcinoma cells binding to AURKA mRNA.

J Cancer 2021 7;12(11):3315-3324. Epub 2021 Apr 7.

The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.

RNA-binding proteins (RBPs) play essential roles in post-transcriptional control of gene expression. Dysregulation of RBPs is intensively implicated in development and progression of human diseases, including cancers. However, the roles of RBPs in nasopharyngeal carcinoma (NPC), which is a distinct subtype of head and neck cancer, remain elusive. Read More

View Article and Full-Text PDF

Thermoelectric transports in pristine and functionalized boron phosphide monolayers.

Sci Rep 2021 May 11;11(1):10030. Epub 2021 May 11.

School of Materials, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

Recently, a new monolayer Group III-V material, two-dimensional boron phosphide (BP), has shown great potential for energy storage and energy conversion applications. We study the thermoelectric properties of BP monolayer as well as the effect of functionalization by first-principles calculation and Boltzmann transport theory. Combined with a moderate bandgap of 0. Read More

View Article and Full-Text PDF

HBD1 protein with a tandem repeat of two HMG-box domains is a DNA clip to organize chloroplast nucleoids in .

Proc Natl Acad Sci U S A 2021 May;118(20)

Department of Botany, Graduate School of Science, Kyoto University, Kita-Shirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan;

Compaction of bulky DNA is a universal issue for all DNA-based life forms. Chloroplast nucleoids (chloroplast DNA-protein complexes) are critical for chloroplast DNA maintenance and transcription, thereby supporting photosynthesis, but their detailed structure remains enigmatic. Our proteomic analysis of chloroplast nucleoids of the green alga identified a protein (HBD1) with a tandem repeat of two DNA-binding high mobility group box (HMG-box) domains, which is structurally similar to major mitochondrial nucleoid proteins transcription factor A, mitochondrial (TFAM), and ARS binding factor 2 protein (Abf2p). Read More

View Article and Full-Text PDF

Dissecting lipid droplet biology with coherent Raman scattering microscopy.

J Cell Sci 2022 Mar 11;135(5). Epub 2021 May 11.

Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.

Lipid droplets (LDs) are lipid-rich organelles universally found in most cells. They serve as a key energy reservoir, actively participate in signal transduction and dynamically communicate with other organelles. LD dysfunction has been associated with a variety of diseases. Read More

View Article and Full-Text PDF

Structural Heterogeneity of Human Histone H2A.1.

J Phys Chem B 2021 May 11. Epub 2021 May 11.

Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.

Histones are highly basic chromatin proteins that tightly package and order eukaryotic DNA into nucleosomes. While the atomic structure of the nucleosomes has been determined, the three-dimensional structure of DNA-free histones remains unresolved. Here, we combine tandem nonlinear and linear ion mobility spectrometry (FAIMS-TIMS) coupled to mass spectrometry in parallel with molecular modeling to study the conformational space of a DNA-free histone H2A type 1 (H2A. Read More

View Article and Full-Text PDF

Low-Temperature and High-Quality Growth of BiOSe Layered Semiconductors Cracking Metal-Organic Chemical Vapor Deposition.

ACS Nano 2021 May 11. Epub 2021 May 11.

Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

Ternary metal-oxy-chalcogenides are emerging as next-generation layered semiconductors beyond binary metal-chalcogenides (, MoS). Among ternary metal-oxy-chalcogenides, especially BiOSe has been demonstrated in field-effect transistors and photodetectors, exhibiting ultrahigh performance with robust air stability. The growth method for BiOSe that has been reported so far is a powder sublimation based chemical vapor deposition. Read More

View Article and Full-Text PDF

HMGB1-like dorsal switch protein 1 of the mealworm, Tenebrio molitor, acts as a damage-associated molecular pattern.

Arch Insect Biochem Physiol 2021 May 11:e21795. Epub 2021 May 11.

Department of Plant Medicals, College of Life Sciences, Andong National University, Andong, Korea.

High-mobility group box 1 (HMGB1) is a nuclear protein highly conserved in eukaryotes and ubiquitously expressed to regulate transcription and chromatin remodeling. Dorsal switch protein 1 (DSP1) is its insect homolog. A lepidopteran DSP1 acts as a damage-associated molecular pattern (DAMP) in response to immune challenge. Read More

View Article and Full-Text PDF

Uptake and bio-transformation of telmisartan by cress (Lepidium sativum) from sewage treatment plant effluents using high-performance liquid chromatography/drift-tube ion-mobility quadrupole time-of-flight mass spectrometry.

Environ Sci Pollut Res Int 2021 May 10. Epub 2021 May 10.

Institute of Analytical Chemistry, Johannes Kepler University, Altenberger Strasse 69, 4040, Linz, Austria.

In the present study, the uptake and metabolization of the sartan drug telmisartan by a series of plants was investigated. Thereby for seven potential metabolites, modifications on the telmisartan molecule such as hydroxylation and/or glycosylation could be tentatively identified. For two additional signals detected at accurate masses m/z 777. Read More

View Article and Full-Text PDF

Alligators employ intermetatarsal reconfiguration to modulate plantigrade ground contact.

J Exp Biol 2021 May 11. Epub 2021 May 11.

Department of Ecology and Evolutionary Biology, Division of Biology and Medicine, Brown University, Providence, RI, USA.

Feet must mediate substrate interactions across an animal's entire range of limb poses used in life. Metatarsals, the 'bones of the sole,' are the dominant pedal skeletal elements for most tetrapods. In plantigrade species that walk on the entirety of their sole, such as living crocodylians, intermetatarsal mobility offers the potential for a continuum of reconfiguration within the foot itself. Read More

View Article and Full-Text PDF

Large-scale growth of few-layer two-dimensional black phosphorus.

Nat Mater 2021 May 10. Epub 2021 May 10.

Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, People's Republic of China.

Two-dimensional materials provide opportunities for developing semiconductor applications at atomistic thickness to break the limits of silicon technology. Black phosphorus (BP), as a layered semiconductor with controllable bandgap and high carrier mobility, is one of the most promising candidates for transistor devices at atomistic thickness. However, the lack of large-scale growth greatly hinders its development in devices. Read More

View Article and Full-Text PDF

Cytotoxic effects of wildfire ashes: In-vitro responses of skin cells.

Environ Pollut 2021 Apr 30;285:117279. Epub 2021 Apr 30.

CESAM (Centre for Environmental and Marine Studies), University of Aveiro, Aveiro, Portugal; Department of Environment and Planning, University of Aveiro, Aveiro, Portugal.

Wildfires are a complex environmental problem worldwide. The ashes produced during the fire bear metals and PAHs with high toxicity and environmental persistence. These are mobilized into downhill waterbodies, where they can impair water quality and human health. Read More

View Article and Full-Text PDF

Function and disability status among women with fistula using WHODAS2.0: A descriptive study from Rwanda and Democratic Republic of Congo.

Int J Gynaecol Obstet 2021 May 10. Epub 2021 May 10.

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Objective: To assess function and disability among women in Rwanda and Democratic Republic of Congo living with fistula and identify characteristics associated with higher disability scores.

Methods: Women presenting for fistula care were recruited. Eligible participants underwent a physical examination to classify fistula type and completed WHODAS 2. Read More

View Article and Full-Text PDF

The End of the Partnership With a Guide Dog: Emotional Responses, Effects on Quality of Life and Relationships With Subsequent Dogs.

Front Vet Sci 2021 22;8:543463. Epub 2021 Apr 22.

Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.

Guide dogs are mobility aids that facilitate independent travel of people who are blind or visually impaired. Additional benefits imparted to the guide dog handler include companionship, and increased: social-function, self-esteem and confidence. Some evidence shows that the end of the guide dog partnership can result in reduced mobility, and may have profound psychosocial effects on the handler due to feelings of bereavement and loss of self-esteem. Read More

View Article and Full-Text PDF

DDX54 Plays a Cancerous Role Through Activating P65 and AKT Signaling Pathway in Colorectal Cancer.

Front Oncol 2021 21;11:650360. Epub 2021 Apr 21.

Department of Pathology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Colorectal cancer (CRC) is one of the most malignant cancers, and its incidence is still steadily increasing. The DDX RNA helicase family members have been found to play a role in various cancers; however, the role of DDX54 in colorectal cancer is still unclear and needed to be defined. Here, we found DDX54 was overexpressed in CRC tissues by the label-free mass spectrum, which was also verified in tissue microarray of colon cancer, as well as the CRC cell lines and TCGA database. Read More

View Article and Full-Text PDF

Quality of life in patients with Marfan syndrome: a cross-sectional study of 102 adult patients.

Cardiovasc Diagn Ther 2021 Apr;11(2):602-610

Department of Sport and Health Sciences, Chair of Sport Psychology, Technical University Munich, Munich, Germany.

Background: Marfan syndrome (MFS) is a genetically determined multiorgan disease that leads to severe physiological and psychological impairments in adult life. Little consensus exists regarding quality of life (QOL) in individuals with MFS. The present study sought to investigate QOL in a representative cohort of adults with MFS. Read More

View Article and Full-Text PDF

Revealing the dynamic adsorption and diffusion of peptide amphiphile on supported lipid bilayer by single molecule experiment and simulation.

Colloids Surf B Biointerfaces 2021 May 1;204:111809. Epub 2021 May 1.

Key Laboratory of Materials Chemistry for Energy Conversion and Storage (HUST) of Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST), Wuhan, 430074, China.

Dynamic adsorption and diffusion of peptide amphiphiles (PAs) with different numbers of alkyl tails on supported lipid bilayers (SLBs) were investigated by single molecule tracking experiment and molecule dynamic simulation. Experimental results show two distinct populations of PAs with different residence time. Residence time of adsorbed PAs increases with the increase of the alkyl tails, whereas diffusion coefficient monotonically decreases with rising the number of alkyl tails and also decreases with increasing the mobility of SLBs. Read More

View Article and Full-Text PDF

Evaluation of four field portable devices for the rapid detection of mitragynine in suspected kratom products.

J Pharm Biomed Anal 2021 Apr 30;201:114104. Epub 2021 Apr 30.

U.S. Food and Drug Administration, Forensic Chemistry Center, 6751 Steger Drive, Cincinnati, OH, 45237, USA. Electronic address:

The development of a method for the rapid screening of food and drug products for constituents such as mitragynine, the most abundant alkaloid found in Mitragyna speciosa (kratom) plant leaves, has become increasingly important. The use of kratom is said to produce stimulant or narcotic effects and poses risks of addiction, abuse, and dependence, much like other opioids. Direct Analysis in Real Time with thermal desorption mass spectrometry (DART-TD-MS), hand-held mass spectrometry, portable ion mobility spectrometry (IMS), and portable Fourier-transform infrared spectroscopy (FT-IR) were each evaluated as field-deployable screening techniques for the detection of mitragynine in food and drug products. Read More

View Article and Full-Text PDF

Distribution, behaviour, bioavailability and remediation of poly- and per-fluoroalkyl substances (PFAS) in solid biowastes and biowaste-treated soil.

Environ Int 2021 May 5;155:106600. Epub 2021 May 5.

Department of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA; Department of Agronomy, Kansas State University, Manhattan, KS 66506, USA.

Aqueous film-forming foam, used in firefighting, and biowastes, including biosolids, animal and poultry manures, and composts, provide a major source of poly- and perfluoroalkyl substances (PFAS) input to soil. Large amounts of biowastes are added to soil as a source of nutrients and carbon. They also are added as soil amendments to improve soil health and crop productivity. Read More

View Article and Full-Text PDF

Hydrothermally-altered feldspar as an environmentally-friendly technology to promote heavy metals immobilization: Batch studies and application in smelting-affected soils.

J Environ Manage 2021 May 5;291:112711. Epub 2021 May 5.

School of Agricultural Sciences, Department of Soil Science, Federal University of Lavras, Lavras, MG, Brazil. Electronic address:

Hydrothermally-altered feldspar (HydroPotash, HYP) possesses, among other physicochemical properties, high pH buffering and cation exchange capacity. Therefore, it may potentially remove heavy metals from aqueous solutions and immobilize these metals in contaminated soil. This study aimed to evaluate the capabilities of two types of HydroPotash (HYP-1 and HYP-2) and a zeolite sample (a commercial adsorbent) for immobilizing cadmium (Cd), zinc (Zn), and lead (Pb) from both aqueous solution and contaminated soils from a Zn-smelting area (classified as soil, soil, and soil based on their level of soluble metal concentration). Read More

View Article and Full-Text PDF

Regulating Utilization Efficiency of the Photogenerated Charge Carriers by Constructing Donor-π-Acceptor Polymers for Upgrading Photocatalytic CO2 Reduction.

ChemSusChem 2021 May 7. Epub 2021 May 7.

CAS Institute of Process Engineering: Institute of Process Engineering Chinese Academy of Sciences, Innovation Academy for Green Manufacture, CHINA.

Photocatalytic CO 2 reduction offers a promising approach for managing global carbon balance. The smooth delivery of the photoexcited electrons to the active sites without the extra photosensitizers is still challenges. Herein, we reported a series of donor-π-acceptor conjugated organic polymers (COPs) using anthracene, cobalt-coordinated bipyridyl and benzene as donor, acceptor, and π linker units, respectively. Read More

View Article and Full-Text PDF

Prevalence of Venous Thromboembolism Following Acute Spinal Cord Injury in an Urban Inner City Hospital.

Int J Spine Surg 2021 May 7. Epub 2021 May 7.

Temple University Department of Orthopedic Surgery and Sports Medicine, Philadelphia, Pennsylvania.

Background: Venous thromboembolism (VTE) is known to occur at high rates in patients who suffer spinal cord injury (SCI). Large population studies in the United States have shown a prevalence of approximately 4-5%, with some studies suggesting higher prevalence. While the specific mechanism behind increased VTE incidence in the SCI population is unknown, it is likely tied to immobility and functional decline. Read More

View Article and Full-Text PDF

How to Select the Lower Instrumented Vertebra in Traditional Growing Rods Index Surgery.

Int J Spine Surg 2021 May 7. Epub 2021 May 7.

Spine Unit, Department of Orthopedic Surgery, Hospital Universitario La Paz, Madrid, Spain.

Background: There are still no consensus criteria on how to select the lower instrumented vertebra (LIV) for traditional growing rods (TGRs) at index surgery. The aim was to evaluate whether the criteria used for adolescent idiopathic scoliosis fusion adapts to early onset scoliosis (EOS).

Methods: Retrospective analysis of prospectively longitudinal collected data in a consecutive cohort of patients with EOS treated with TGR, expanding from index surgery to 2 years after graduation. Read More

View Article and Full-Text PDF