Histochem Cell Biol 2019 Nov 13;152(5):355-363. Epub 2019 Sep 13.
Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, v.v.i, Academy of Sciences of the Czech Republic, Veveri 97, Brno, Czech Republic.
Tuftelin was originally discovered and mostly studied in the tooth, but later found also in other organs. Despite its wide distribution among tissues, tuftelin's function has so far been specified only in the formation of enamel crystals. Nevertheless, in many cases, tuftelin was suggested to be associated with cellular adaptation to hypoxia and recently even with cell differentiation. Read More