68,737 results match your criteria hemodynamic parameters


Evaluation and verification of patient-specific modelling of type B aortic dissection.

Comput Biol Med 2021 Nov 23;140:105053. Epub 2021 Nov 23.

Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK. Electronic address:

Quantitative assessment of the complex hemodynamic environment in type B aortic dissection (TBAD) through computational fluid dynamics (CFD) simulations can provide detailed insights into the disease and its progression. As imaging and computational technologies have advanced, methodologies have been developed to increase the accuracy and physiological relevance of CFD simulations. This study presents a patient-specific workflow to simulate blood flow in TBAD, utilising the maximum amount of in vivo data available in the form of CT images, 4D-flow MRI and invasive Doppler-wire pressure measurements, to implement the recommended current best practice methodologies in terms of patient-specific geometry and boundary conditions. Read More

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November 2021

Pharmacokinetics of Commonly Used Medications in Children Receiving Continuous Renal Replacement Therapy: A Systematic Review of Current Literature.

Clin Pharmacokinet 2021 Nov 30. Epub 2021 Nov 30.

School of Pharmacy, University of Waterloo, 10 Victoria St S. Kitchener, Waterloo, ON, N2G 1C5, Canada.

Background And Objective: The use of continuous renal replacement therapy (CRRT) for renal support has increased substantially in critically ill children compared with intermittent modalities owing to its preferential effects on hemodynamic stability. With the expanding role of CRRT, the quantification of extracorporeal clearance and the effect on primary pharmacokinetic parameters is of the utmost importance. Within this review, we aimed to summarize the current state of the literature and compare published pharmacokinetic analyses of commonly used medications in children receiving CRRT to those who are not. Read More

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November 2021

PEGylated Graphene Quantum Dot Improved Cardiac Function in Rats with Myocardial Infarction: Morphological, Oxidative Stress, and Toxicological Evidences.

Oxid Med Cell Longev 2021 20;2021:8569225. Epub 2021 Nov 20.

Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Introduction: The biocompatibility and potential application of graphene-based nanomaterials in biomedicine have been documented. The effects of polyethylene glycol-graphene quantum dots (GQDs-PEG) on cardiac function in rats with myocardial infarction (MI) were examined.

Methods: Wistar rats were randomly assigned to two main groups, each consisting of sham-Veh. Read More

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November 2021

Indoor cycling training in rehabilitation of patients after myocardial infarction.

BMC Sports Sci Med Rehabil 2021 Nov 29;13(1):151. Epub 2021 Nov 29.

Faculty of Health Science, Jan Dlugosz University, 42-200, Czestochowa, Poland.

Background: Standard endurance training used from the second stage of cardiac rehabilitation has many common features with indoor cycling training which is used in fitness clubs. In the study, an attempt was made to evaluate the usefulness of this form of training in a 24-day rehabilitation program for patients after myocardial infarction. The study examined a group of 64 patients (51. Read More

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November 2021

[Invasive Cardiopulmonary Exercise Testing: A Review].

Pneumologie 2021 Nov 29. Epub 2021 Nov 29.

DRK Kliniken Berlin Westend, Klinik für Innere Medizin, Schwerpunkt Kardiologie, Berlin.

Right heart catheterization (RHC) is the internationally standardized reference method for measuring pulmonary hemodynamics under resting conditions. In recent years, increasing efforts have been made to establish the reliable assessment of exercise hemodynamics as well, in order to obtain additional diagnostic and prognostic data. Furthermore, cardiopulmonary exercise testing (CPET), as the most comprehensive non-invasive exercise test, is increasingly performed in combination with RHC providing detailed pathophysiological insights into the exercise response, so-called invasive cardiopulmonary exercise testing (iCPET). Read More

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November 2021

Arterial stiffness, carotid intima-media thickness, endocan and A disintegrin-like and metalloprotease with thrombospondin type I motif 9 levels and their relationship with disease activity in acromegaly patients with and without cardiovascular risk factors.

Endocr Pract 2021 Nov 26. Epub 2021 Nov 26.

Department of Endocrinology and Metabolism, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.

Objective: Cardiovascular complications such as cardiomyopathy and endothelial dysfunction, which are frequently seen in patients with acromegaly, are among the most important causes of morbidity and mortality. In this study, we aimed to investigate arterial stiffness, carotid intima-media thickness, endocan and A disintegrin-like and metalloprotease with thrombospondin type I motif 9 (ADAMTS9) levels and their relationship with disease activity in acromegaly patients with and without cardiovascular risk factors.

Design: A total of 60 patients with acromegaly, 25 with active disease, 26 with well-controlled disease, and 9 newly diagnosed, and 60 age-, sex- and body mass index (BMI)-matched healthy control subjects were enrolled in this study. Read More

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November 2021

Patient-specific hemodynamic analysis of IVCS-induced DVT.

Comput Methods Biomech Biomed Engin 2021 Nov 29:1-11. Epub 2021 Nov 29.

Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

The aim of this study is to perform patient-specific hemodynamic simulations of patients with iliac vein compression syndrome (IVCS) and evaluate the deep venous thrombosis (DVT) potential, with clinical observations as reference. 15 patient-specific IVCS models were reconstructed from computed tomography venography (CTV) data, and divided into three groups, i.e. Read More

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November 2021

Near-Term Cerebroplacental Doppler, Heart Morphology, and Neonatal Biometry in Hypoplastic Left Heart Syndrome.

J Ultrasound Med 2021 Nov 29. Epub 2021 Nov 29.

Department of Obstetrics and Gynecology in Ruda Slaska, Medical University of Silesia, Ruda Śląska, Poland.

Objectives: To analyze near-term cerebroplacental Doppler, heart morphology, and neonatal biometry in isolated hypoplastic left heart syndrome (HLHS) relative to healthy controls.

Methods: This retrospective study included 55 fetuses with HLHS (29 with mitral valve stenosis [MS]/aortic valve atresia [AA], 14 with MS/aortic valve stenosis, and 12 with mitral valve atresia [MA]/[AA]) diagnosed prenatally between 2010 and 2019 at 2 referral centers and 101 healthy controls. Ultrasound assessment included umbilical artery (UA), middle cerebral artery (MCA) pulsatility index (PI), and cerebroplacental ratio (CPR), with neonatal weight, length, head circumference (HC), Apgar score, and UA pH measured at birth. Read More

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November 2021

Adenosine, Lidocaine, and Magnesium for Attenuating Ischemia Reperfusion Injury from Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in a Porcine Model.

J Trauma Acute Care Surg 2021 Nov 29. Epub 2021 Nov 29.

Madigan Army Medical Center Madigan Army Medical Center Madigan Army Medical Center Madigan Army Medical Center Madigan Army Medical Center Madigan Army Medical Center Madigan Army Medical Center University of North Carolina Medical Center Madigan Army Medical Center.

Background: Minimally invasive REBOA following non-compressible hemorrhage results in significant ischemia reperfusion injury (IRI). Adverse outcomes from IRI include organ dysfunction and can result in profound hemodynamic and molecular compromise. We hypothesized that ALM attenuates organ injury and inflammation responses following REBOA IRI in a porcine model of hemorrhage. Read More

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November 2021

Whole Blood Versus Conventional Blood Component Massive Transfusion Protocol Therapy in Civilian Trauma Patients.

Am Surg 2021 Nov 27:31348211049752. Epub 2021 Nov 27.

Department of Trauma and Acute Care Surgery, 2604University of Colorado Health Memorial Hospital, Colorado Springs, CO, USA.

Background: Military data demonstrating an improved survival rate with whole blood (WB) have led to a shift toward the use of WB in civilian trauma. The purpose of this study is to compare a low-titer group O WB (LTOWB) massive transfusion protocol (MTP) to conventional blood component therapy (BCT) MTP in civilian trauma patients.

Methods: Trauma patients 15 years or older who had MTP activations from February 2019 to December 2020 were included. Read More

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November 2021

Intranasal Dexmedetomidine in Elderly Patients (Aged > 65 Years) During Maxillofacial Surgery: Sedative Properties and Safety Analysis.

J Oral Maxillofac Surg 2021 Oct 30. Epub 2021 Oct 30.

Assistant Professor, Department of Anesthesiology, People's hospital of beilun district, Ningbo city, Zhejiang province, Ningbo, Zhejiang, China.

Purpose: Light sedation rather than intravenous sedation is preferred when patients have a low heart rate and blood pressure during maxillofacial surgery. Intranasal administration of dexmedetomidine is reported to be efficacious and safe in adults. However, dexmedetomidine could be unsuitable for routine clinical use in elderly patients because many of these patients take β-blockers, which increase the cardiovascular effects of dexmedetomidine. Read More

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October 2021

Implantable devices for heart failure monitoring.

Prog Cardiovasc Dis 2021 Nov 25. Epub 2021 Nov 25.

Division of Cardiovascular Medicine, Lahey Hospital and Medical Center, Burlington, MA, United States of America.

Heart failure (HF) is associated with considerable morbidity and mortality. The increasing prevalence of HF and inpatient HF hospitalization has a considerable burden on healthcare cost and utilization. The recognition that hemodynamic changes in pulmonary artery pressure (PAP) and left atrial pressure precede the signs and symptoms of HF has led to interest in hemodynamic guided HF therapy as an approach to allow earlier intervention during a heart failure decompensation. Read More

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November 2021

Abdominal applications of quantitative 4D flow MRI.

Abdom Radiol (NY) 2021 Nov 27. Epub 2021 Nov 27.

Department of Radiology, University of Wisconsin, 600 Highland Ave, Madison, WI, 53792, USA.

4D flow MRI is a quantitative MRI technique that allows the comprehensive assessment of time-resolved hemodynamics and vascular anatomy over a 3-dimensional imaging volume. It effectively combines several advantages of invasive and non-invasive imaging modalities like ultrasound, angiography, and computed tomography in a single MRI acquisition and provides an unprecedented characterization of velocity fields acquired non-invasively in vivo. Functional and morphological imaging of the abdominal vasculature is especially challenging due to its complex and variable anatomy with a wide range of vessel calibers and flow velocities and the need for large volumetric coverage. Read More

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November 2021

Maximal exercise outcomes with a face mask: the effects of gender and age differences on cardiorespiratory responses.

Ir J Med Sci 2021 Nov 26. Epub 2021 Nov 26.

Physiotherapy and Rehabilitation Department, School of Health Sciences, KTO Karatay University, Alaaddin Kap St. No:130, 42020, Karatay, Konya, Turkey.

Background: Surgical masks have become an important accessory of physical activity in daily life due to the COVID-19 pandemic.

Aims: To determine the effects of the surgical mask on respiratory gas exchange parameters, dyspnoea, and hemodynamic responses during maximal exercise in different age groups and gender.

Methods: Twenty-six healthy participants between 18 and 65 years (mean 37. Read More

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November 2021

Leaky Gut Syndrome Is Associated with Endotoxemia and Serum (1→3)-β-D-Glucan in Severe Dengue Infection.

Microorganisms 2021 Nov 19;9(11). Epub 2021 Nov 19.

Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

The hallmark of severe dengue infection is the increased vascular permeability and hemodynamic alteration that might be associated with an intestinal permeability defect. However, the mechanisms underlying the gastrointestinal-related symptoms of dengue are not well characterized. A prospective observational study was conducted on patients with dengue who were categorized according to: (i) febrile versus critical phase and (ii) hospitalized patients with versus without the warning signs to evaluate the gut barrier using lactulose-to-mannitol excretion ratio (LEMR). Read More

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November 2021

An Anti-Jamming Method against Two-Dimensional Deception Jamming by Spatial Location Feature Recognition.

Sensors (Basel) 2021 Nov 19;21(22). Epub 2021 Nov 19.

The Institute of Information and Navigation, Air Force Engineering University, Xi'an 710077, China.

Interrupted sampling repeater jamming (ISRJ) is an effective method for implementing deception jamming on chirp radars. By means of frequency-shifting jamming processing of the target echo signal and pulse compression during image processing, a group of false targets will appear in different spatial locations around the true target. Extracting the features of these false targets is complex and limited to existing countering methods against ISRJ. Read More

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November 2021

Invisible ECG for High Throughput Screening in eSports.

Sensors (Basel) 2021 Nov 16;21(22). Epub 2021 Nov 16.

IT-Instituto de Telecomunicações, 1049-001 Lisboa, Portugal.

eSports is a rapidly growing industry with increasing investment and large-scale international tournaments offering significant prizes. This has led to an increased focus on individual and team performance with factors such as communication, concentration, and team intelligence identified as important to success. Over a similar period of time, personal physiological monitoring technologies have become commonplace with clinical grade assessment available across a range of parameters that have evidenced utility. Read More

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November 2021

Mitochondria Isolated from Hearts Subjected to Ischemia/Reperfusion Benefit from Adenine Nucleotide Translocase 1 Overexpression.

Membranes (Basel) 2021 Oct 29;11(11). Epub 2021 Oct 29.

Physiologisches Institut, Justus-Liebig-Universität Gießen, 35392 Gießen, Germany.

Reperfusion is the only feasible therapy following myocardial infarction, but reperfusion has been shown to damage mitochondrial function and disrupt energy production in the heart. Adenine nucleotide translocase 1 (ANT1) facilitates the transfer of ADP/ATP across the inner mitochondrial membrane; therefore, we tested whether ANT1 exerts protective effects on mitochondrial function during ischemia/reperfusion (I/R). The hearts of wild-type (WT) and transgenic ANT1-overexpressing (ANT1-TG) rats were exposed to I/R injury using the standard Langendorff technique, after which mitochondrial function, hemodynamic parameters, infarct size, and components of the contractile apparatus were determined. Read More

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October 2021

Immediate Effects of Whole-Body Vibration Associated with Squatting Exercises on Hemodynamic Parameters in Sarcopenic Older People: A Randomized Controlled Trial.

Int J Environ Res Public Health 2021 Nov 12;18(22). Epub 2021 Nov 12.

MATIM, Department of Sport Science, Université de Reims, CEDEX 2, 51687 Reims, France.

Whole-body vibration (WBV) exercises have recently been introduced as a nonpharmacological therapeutic strategy for sarcopenic older people. The present study aimed to evaluate the effect of WBV exercise on hemodynamic parameters in sarcopenic older people. Forty older people, divided into groups of nonsarcopenic (NSG = 20) and sarcopenic (SG = 20), participated in the study and were cross randomized into two interventions of eight sets of 40 s each, these being squatting with WBV and squatting without WBV. Read More

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November 2021

Long-Term Cardiac Sequelae in Patients Referred into a Diagnostic Post-COVID-19 Pathway: The Different Impacts on the Right and Left Ventricles.

Diagnostics (Basel) 2021 Nov 6;11(11). Epub 2021 Nov 6.

Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.

Most patients who had COVID-19 are still symptomatic after many months post infection, but the long-term outcomes are not yet well defined. The aim of our prospective/retrospective study was to define the cardiac sequelae of COVID-19 infection. This monocentric cohort study included 160 consecutive patients who had been discharged from the ward or from the outpatient clinic after a diagnosis of COVID-19 and subsequently referred for a follow-up visit. Read More

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November 2021

Effect of Roller Pump Pulse in the Arterial Needle Area during Hemodialysis.

Diagnostics (Basel) 2021 Oct 29;11(11). Epub 2021 Oct 29.

3rd Department Internal Medicine and General University Hospital, First Medical Faculty, Charles University, U Nemocnice 1, 128 08 Prague, Czech Republic.

Vascular access is a lifeline for hemodialysis patients. Its lifetime is affected by many hemodynamic factors such as pressure, flow regime and wall shear stress. During hemodialysis, changes in hemodynamic parameters occur due to the flow from needles inserted into the vascular system. Read More

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October 2021

Integration of the Cortical Haemodynamic Response Measured by Functional Near-Infrared Spectroscopy and Amino Acid Analysis to Aid in the Diagnosis of Major Depressive Disorder.

Diagnostics (Basel) 2021 Oct 25;11(11). Epub 2021 Oct 25.

Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

Background: Major depressive disorder (MDD) is a debilitating condition with a high disease burden and medical comorbidities. There are currently few to no validated biomarkers to guide the diagnosis and treatment of MDD. In the present study, we evaluated the differences between MDD patients and healthy controls (HCs) in terms of cortical haemodynamic responses during a verbal fluency test (VFT) using functional near-infrared spectroscopy (fNIRS) and serum amino acid profiles, and ascertained if these parameters were correlated with clinical characteristics. Read More

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October 2021

Performance of the Jarvik 2000 left ventricular assist device on mid-term hemodynamics and exercise capacity.

J Artif Organs 2021 Nov 26. Epub 2021 Nov 26.

Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.

The hemodynamic and exercise capacity performance of the Jarvik 2000 left ventricular assist device (LVAD), which is generally used in patients with small body size and relatively preserved cardiac function, is not well understood. We retrospectively examined 18 patients implanted with the Jarvik 2000 LVAD. Pump rotation speed was optimized by the hemodynamic ramp test one year after implantation based on the criteria of mean pulmonary capillary wedge pressure (PCWP) < 18 mmHg, mean right atrial pressure (RAP) < 12 mmHg, and cardiac index (CI) > 2. Read More

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November 2021

Hemodynamic Changes Provoked through Intravascular Injection of the Venom in Rats.

Arch Razi Inst 2021 1;76(3):599-607. Epub 2021 Sep 1.

Department of Pharmacology, Bushehr University of Medical Sciences, Bushehr, Iran.

() is known for its hematological and nephrotoxic properties in the envenomed patients. Based on the limited data upon the cardiovascular changes associated with this dangerous venomous snake in Iran, the current study purposed to evaluate the venom-induced hemodynamic manifestations in rats. Venom (120 µg/kg) was administered intravenously within one minute through the left femoral vein, and the hemodynamic parameters were continuously recorded using a pressure transducer (MLT844, ADInstruments, Australia). Read More

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November 2021

Selexipag for the treatment of chronic thromboembolic pulmonary hypertension.

Eur Respir J 2021 Nov 25. Epub 2021 Nov 25.

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan.

Treatment options for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) remain limited. Selexipag, an oral selective IP prostacyclin-receptor agonist approved for pulmonary arterial hypertension, is a potential treatment option for CTEPH.In this multicentre, randomised, double-blind, placebo-controlled study, 78 Japanese patients with inoperable CTEPH or persistent/recurrent pulmonary hypertension after pulmonary endarterectomy and/or balloon pulmonary angioplasty were randomly assigned to receive placebo or selexipag. Read More

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November 2021

Potentilla reptans L. postconditioning protects reperfusion injury via the RISK/SAFE pathways in an isolated rat heart.

BMC Complement Med Ther 2021 Nov 26;21(1):288. Epub 2021 Nov 26.

Ischemic Disorders Research Center, Golestan University of Medical Sciences, P.O.BOX. 4934174515, Gorgan, Iran.

Background: Our previous study indicated that Potentilla reptans root has a preconditioning effect by its antioxidant and anti-apoptotic effects in an isolated rat heart ischemia/reperfusion (IR) model. In the present study, we investigated the post-conditioning cardio-protective effects of Potentilla reptans and its active substances.

Methods: The ethyl acetate fraction of P. Read More

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November 2021

Non-invasive fetal electrocardiography, electrohysterography and speckle-tracking echocardiography in the second trimester: study protocol of a longitudinal prospective cohort study (BEATS-study).

BMC Pregnancy Childbirth 2021 Nov 25;21(1):791. Epub 2021 Nov 25.

Department of Gynaecology and Obstetrics, Máxima MC, P.O. Box 7777, 5500 MB, Veldhoven, The Netherlands.

Background: Worldwide, hypertensive disorders of pregnancy (HDP), fetal growth restriction (FGR) and preterm birth remain the leading causes of maternal and fetal pregnancy-related mortality and (long-term) morbidity. Fetal cardiac deformation changes can be the first sign of placental dysfunction, which is associated with HDP, FGR and preterm birth. In addition, preterm birth is likely associated with changes in electrical activity across the uterine muscle. Read More

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November 2021

Fetal pulmonary hemodynamics: Doppler reference values in low risk pregnancies.

J Matern Fetal Neonatal Med 2021 Nov 25:1-7. Epub 2021 Nov 25.

European Medical and Research Center (CEMER), Perugia, Italy.

Objective: To investigate fetal pulmonary hemodynamics in normal pregnancy using pulsed and color Doppler ultrasonography and to define Doppler reference ranges values in the whole fetal pulmonary circulation during different gestational ages.

Materials And Methods: A prospective observational study was conducted to evaluate 190 healthy singleton pregnancies between 20 and 38 weeks of gestation, including 10 cases for each gestational age. The main pulmonary artery, right pulmonary artery, left pulmonary artery, ductus arteriosus and pulmonary veins waveforms were evaluated. Read More

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November 2021

Efficacy of intranasal ketamine and midazolam for pediatric sedation: A double-blind, randomized clinical trial.

Caspian J Intern Med 2021 ;12(4):539-543

Student Research Committee, Guilan University of Medical Sciences, Rasht, Iran.

Background: Pediatric patients feel significant fear and anxiety when undergoing surgeries. The ideal drug and its administration route have not been found yet. The aim of this study was to compare the efficacy and safety of intranasal (IN) ketamine and midazolam as premedication in children. Read More

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January 2021

The Effect of Early Mobilization on Respiratory Parameters of Mechanically Ventilated Patients With Respiratory Failure.

Crit Care Nurs Q 2022 Jan-Mar 01;45(1):74-82

School of Nursing and Midwifery (Mr Rezvani), Nursing and Midwifery Care Research Center, School of Nursing and Midwifery (Dr Esmaeili), and Advanced Thoracic Research Center (Dr Rahimi), Tehran University of Medical Sciences, Tehran, Iran; and Department of Biostatistics, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran (Dr Maroufizadeh).

The effect of early mobilization on hemodynamic parameters of patients under mechanical ventilation has been associated with positive results and yet its effect on specific respiratory parameters is less well appreciated. This article reports the results of a study of a randomized clinical trial of intensive care unit patients receiving mechanical ventilation. The findings of this study confirmed that a 4-step protocol for early mobilization can improve Pao2, O2 saturation, Pao2/Fio2 (fraction of inspired oxygen) ratio, and pulmonary compliance. Read More

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November 2021